Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
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Optimising dissemination mechanisms for Malaria clinical practice guidelines in the evidence ecosystem.
(MARC-SE-MAGIC)
REFNo: HS5591ES
To study different dissemination mechanisms, customized to health care professionals or other end users of clinical practice guidelines.
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Uganda |
2025-03-04 13:11:00 |
2028-03-04 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Kayabula Alex
ID: UNCST-2023-R005649
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Leaders' Personality, Leadership Styles, and Employee Retention in Selected Universities in Central Uganda
REFNo: SS3673ES
Specific Objectives
1. To examine the relationship between introversion and employee retention in in selected universities in central Uganda.
2. To investigate the influence of extroversion on employee retention in selected universities in central Uganda
3. To explore the impact of democratic leadership style on employee retention in selected universities in central Uganda
4. To assess the combined effect of leaders’ personality and leadership styles on employee retention in selected universities in central Uganda
5. To analyze the moderating role of work environment on the relationship between leaders’ personality, leadership styles, and employee retention in selected universities in central Uganda.
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Uganda |
2025-03-04 13:03:54 |
2028-03-04 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Moses Joloba Lutaakome
ID: UNCST-2022-R011558
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Antibiotic Resistance Surveillance and Antimicrobial Stewardship
Strengthening in the Karamoja Sub-region (ARSK)
REFNo: HS5566ES
2.2.1 To determine the patterns and prevalence of antimicrobial resistance (AMR) in Napak and Moroto districts of Uganda.
2.2.2 To evaluate the knowledge, attitudes, and practices (KAP) related to antimicrobial resistance (AMR), antibiotic use, and antimicrobial stewardship (AMS) among healthcare workers (HCWs), patients, and their caretakers in Napak and Moroto districts.
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Uganda |
2025-03-04 13:01:32 |
2028-03-04 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Lorna Atikoro
ID: UNCST-2024-R002527
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Improving diagnostics of Antimicrobial Resistance (AMR) in Sub-Saharan Africa- A multicenter project of the COMBAT AMR in Africa network
REFNo: HS5555ES
. To determine the concordance of the point of care tests NG-Test CTX-M MULTI©, NGTest CARBA 5© and NG Test MCR-1© in the diagnosis of extended spectrum beta
lactamases, carbapenemases and colistin resistant bacteria respectively with conventional
phenotypic culture.
• To determine the 28- day clinical outcomes of patients with multi drug resistant gram negative bacteria.
• To identify the mechanisms leading to inconsistent results between the POCTs and
conventional phenotypic culture.
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Uganda |
2025-03-04 12:23:18 |
2028-03-04 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Jenny Löfgren
ID: UNCST-2024-R005428
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Orthopaedic trauma, infections and cancer care in Uganda - Disease panorama, management and barriers to care
REFNo: HS5535ES
Investigate complication rates after orthopaedic surgery performed in the study hospitals.,To investigate the proportion of patients with traumatic, infectious and malignant orthopaedic conditions that receive surgical versus non-surgical treatment in the study hospitals,The main objective of the study is to study the management and outcomes of a variety of traumatic, infectious and malignant orthopaedic conditions that are common in secondary and tertiary level hospital settings,To identify current health care gaps in the provision of management of traumatic, infectious and malignant orthopaedic conditions in Uganda. ,To investigate barriers and promoting factors to accessing care for pathological fractures ,Identify rates of complications (revision due to malalignment, infection, technical error) from surgery performed in low-resource settings.,Compare patient functional outcomes if the patient is treated non-surgically, treated surgically within 2 weeks of injury or treated surgically later than 2 weeks after the injury.,
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Sweden |
2025-03-04 11:09:42 |
2028-03-04 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Sarah Kiguli
ID: UNCST-2021-R013020
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Observational Study to Assess the Incidence of Malaria among Children Living with Sickle Cell Disease in Jinja Regional Referral Hospital Eastern Uganda.
REFNo: HS5583ES
General Objective
To describe the epidemiology of malaria in SCD patients in Uganda.
Specific objectives:
Primary Objective
1. To determine the incidence of malaria cases in SCD patients over a 12-month period.
1. Secondary objectives
2. To determine the incidence of asymptomatic parasitemia aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period?.
3. To determine the incidence of submicroscopic parasitemia aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period?.
4. To determine the severity of malaria in SCD patients, including the prevalence of WHO-defined severe malaria complications such as cerebral malaria, respiratory distress, and severe anemia aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period?.
5. To determine the frequency of sickle cell disease complications associated with a malaria case.
6. To identify temporal patterns in malaria incidence aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period
7. To examine the risk and protective factors associated with malaria susceptibility and severity among malaria-infected SCD patients using malaria chemoprophylaxis.
Exploratory endpoints:
8. To investigate and determine the parasite molecular diversity among SCD patients attending Jinja Regional Referral Hospital?
9. To examine and determine the antimalarial parasite drug resistance patterns among SCD patients
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Uganda |
2025-03-04 10:54:17 |
2028-03-04 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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HIRALY ASABAHEBWA
ID: UNCST-2024-R016374
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A QUALITATIVE STUDY EXPLORING THE EXPERIENCES OF UNIVERSITY STUDENTS LIVING WITH HIV AND COMPLETING A UNIVERSITY-LEVEL QUALIFICATION IN KAMPALA, UGANDA
REFNo: SS3684ES
To explore the experiences of newly HIV-diagnosed university students in Kampala, Uganda ,
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Uganda |
2025-03-04 10:29:29 |
2028-03-04 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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ISMAHIL ADENIYI ADEKUNLE
ID: UNCST-2024-R002602
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EFFECTS OF ETHYL-ACETATE FRACTION OF Bidens pilosa LEAVES ON TESTES AND PITUITARY GLAND OF MALE MICE EXPOSED TO BISPHENOL A
REFNo: HS5372ES
The purpose of this study is to evaluate the impact of B. pilosa on testicular integrity and the pituitary gland of male mice exposed to BPA.
1.3.1 Specific Objectives
i. To assess the effect of B. Pilosa on spermatogenic metrics of the testes such as sperm motility, sperm count, morphology, agglutination, and vitality using routine and extended semen analysis.
ii. To determine the impact of B. pilosa on serum concentration of follicle-stimulating hormone, testosterone, and luteinizing hormone using enzyme-linked immunosorbent assay (ELISA) following BPA exposure.
iii. To assess the changes in testicular oxidative stress biomarkers (such as CAT, SOD, and GSH) and lipid peroxidation using MDA.
iv. To assess the histology, histochemical, and immunohistochemical changes in the testes and pituitary gland following treatment with B. pilosa in BPA exposure using Masson Trichrome, Periodic Acid Schiff (PAS), Hematoxylin and Eosin (H&E), Caspase 3, antiproliferating cell nuclear antigen (PCNA), Bcl-2, alpha-smooth muscle actin (?-SMA), and Bax.
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Nigeria |
2025-03-03 11:40:21 |
2028-03-03 |
Medical and Health Sciences |
Clinical Trial |
Degree Award |
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Agapitus Kato Babumba
ID: UNCST-2021-R013866
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Linking infectious disease front-liners control efforts with central public health authorities in the African Great Lakes region (Great-Life) project
REFNo: HS5293ES
Study Objectives: The study objectives and their specific objectives are outlined in A to D below.
OBJECTIVE A – CAPACITY BUILDING
This objective involves testing the integrated nanopore sequencing capacity (DNA and RNA—single isolates and metagenomics) in the study area.
Specific objectives:
? Set -up sampling, sequencing, and simple bioinformatic/epidemiological capacity in Bidibidi Health Centre.
? Set up advanced bioinformatics/ epidemiological capacity at UVRI and cascade it to the study area health facilities
? Build capacity in genomic data interpretation and risk communication in genomic epidemiology.
OBJECTIVE B - BIOINFORMATICS, EPIDEMIOLOGY, AND INFRASTRUCTURE
This objective involves the testing of standardized laptop analysis and compression of the data generated from nanopore runs, including base calling and standard analysis for use at the frontline health facility (Bidibidi HC III). Following analysis, the analytic data (now the size of kilobytes) can be easily and in real-time shared with stakeholders.
Specific objectives:
? Develop a common understanding of the key data analytics and infrastructure needs.
? Set up a project-specific frontline laptop-based data-entering and bioinformatic pipeline.
? Set up a central data portal for storing, aggregating, and sharing raw data and analytic output.
? Provide operational user support to the use-case scenarios and external users
? Support high-throughput computation capacity
OBJECTIVE C – TRAINING IN RESEARCH TRANSLATION SKILLS, AND EQUITABLE PARTNERSHIP
One of the key elements of this project is to generate data that should be transformed into information that will result in public health actions and social impact in the country. The project will involve key stakeholders from the health facility and local and central governments to meet this goal. The stakeholders will be trained in research data interpretation and utilization. The stakeholders will use the training obtained from this project to develop measures and policies.
Specific objectives:
? Conduct training of public health authorities and researchers in public health uptake of genomic epidemiological data
? Determine how obtained data will result in local and national guidelines for individual patient treatment
? Determine how data will influence local, national, and regional public health interventions
? Investigate how cross-border disease outbreaks can be coordinated between national and regional authorities
OBJECTIVE D - EPIDEMIOLOGICAL AND GENOMIC INVESTIGATIONS
The objectives will be fulfilled by conducting three use cases
? Real-time diagnostic and characterization of diarrheal and persistent malaria cases
? Environmental surveillance for antimicrobial resistance genes in the study area.
? Horizon scanning for pathogens of novel unknown infections of epidemic nature (Disease X identification)
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Uganda |
2025-02-28 17:30:31 |
2028-02-28 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Karim Nanyiri
ID: UNCST-2024-R002952
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Role of Mother Tongue in Learning Productive and Receptive Skills in English language: An Analysis of Perceptions of Stakeholders in Secondary Schools of Bugisu Sub-Region, Eastern Uganda
REFNo: SS3393ES
Objectives of the Study
The study will be guided by the main objective and specific objectives.
Main Objective of the Study
The main objective of the study is to investigate the role of mother tongue in learning productive and receptive skills in English language through the analysis of perceptions of stakeholders in secondary schools of Bugisu sub-region, eastern Uganda.
Specific Objectives of the Study
The study will be conducted with the following specific objectives;
1. To determine the influence of students’ productive skills in mother tongue on the learning of productive skills in English language.
2. To determine the influence of students’ receptive skills in mother tongue on the learning of receptive skills in English language.
3. To explore students’ perception of the role of mother tongue in learning productive skills in English language.
4. To explore students’ perception of the role of mother tongue in learning receptive skills in English language.
5. To explore teachers’ perception of the role of mother tongue in learning productive skills in English language.
6. To explore teachers’ perception of the role of mother tongue in learning receptive skills in English language.
7. To explore the barriers encountered by lower secondary school students in the learning of productive and receptive skills in English language.
|
Uganda |
2025-02-28 16:02:44 |
2028-02-28 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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