Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Claire Norcross Valerie
ID: UNCST-2024-R004641
An observational study evaluating archived and emergent HIV drug resistance in people with a history of sub-optimal HIV control in East and Southern Africa
REFNo: HS4761ES

1. To describe archived resistance mutation patterns (major/minor mutations and minority variants) in adults in East and Southern Africa with a recent history of sub-optimal adherence to dolutegravir-based ART; through next-generation sequencing of pro-viral DNA 2. To describe emergent resistance patterns (major/minor mutations and minority variants) in people living with HIV (PLWH) who fail treatment with long-acting injectable cabotegravir/rilpivirine (LAI-CAB/RPV) and the implications for future treatment, and in those who experience blips on LAI-CAB/RPV, through next-generation sequencing on stored plasma 3. To identify predictors of treatment failure on LAI-CAB/RPV in PLWH in East and Southern Africa, and consider how these predictors can influence policy
UK 2024-08-26 14:52:18 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
David Okimait
ID: UNCST-2019-R000095
We Can Work Baseline for Youth With Disability
REFNo: SS3023ES

To provide relevant recommendations and insights that will further inform the program design and adaptation during the implementation period.,To measure all goal, outcome, and output level indicators as a benchmark for purposes of setting performance targets and measurement of the program progress,The overall purpose of this baseline survey is to establish a benchmark of the program indicators across all five outcomes to inform implementation. This will enable systematic measurement of progress towards the intended results annually and at final evaluation,
Uganda 2024-08-26 14:45:41 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
FREDRICK MAKUMBI
ID:
Rapid Assessment of Bottlenecks Inhibiting the Scale-up of Evidence-based Family Planning Practices in Uganda
REFNo: HS4723ES

Broad objective To understand enablers and inhibitors to the scale-up of three EBPs (PPFP, task sharing/expansion, and SBCC) and FP broadly through a BNA approach to inform strategies that can accelerate the uptake of family planning services and programme implementation in Uganda. Specific objectives 1.To synthesize what is known about scaling up FP EBPs and broader FP in Uganda, including implementation status, alignment of guidance with national and international standards, and the lessons learned from successful implementation (including approaches that aim to address gender norms and inequalities) 2.To understand the perspectives of key stakeholders (policymakers, programme managers, healthcare managers, service providers and civil society) on the various health systems factors inhibiting the scale-up of the EBPs. 3.Build consensus among key stakeholders on the most important bottlenecks to EBP scale-up and on solutions that address the root causes inhibiting scale-up
Uganda 2024-08-26 14:41:30 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
What works to prevent and respond to childhood sexual violence in resource-constrained settings: The Case of the 3RT Model implemented by The Remnant Generation in Uganda
REFNo: SS3005ES

4. To study the contribution of girls’ agency in promoting social norms change to prevent childhood sexual violence.,3. To identify critical enablers for effective implementation of interventions to prevent and respond to childhood sexual violence.,2. To explore the role of communities in leading sustainable change for safe environments free from childhood sexual violence. ,To document the effectiveness of the 3RT model in preventing and responding to childhood sexual violence among adolescents in Uganda.,To scientifically examine what works in preventing and responding to childhood sexual violence in resource-constrained settings using the 3RT model of the Remnant Generation as a case. ,
Uganda 2024-08-26 14:40:04 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Warren Aryeija
ID:
Experiences of People with Infertility in Uganda: Empirical Study of Couples with Infertility Challenges at Selected Hospitals in Kampala City
REFNo: SS2807ES

1. Assess knowledge about the causes of infertility among infertile male and female couples. 2. Identify socio-economic challenges experienced by infertile male and female couples. 3. Examine the psycho-emotional impact of infertility on infertile male and female couples. 4. Explore Coping strategies used by infertile male and female couples in living and dealing with infertility. 5. Determine the Socio-demographic correlates of Coping Strategies adopted by infertile male and female couples.
Uganda 2024-08-26 14:21:31 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Monicah Agaba
ID: UNCST-2024-R004221
The Health-Beauty Paradox among Women in Mbarara City Uganda
REFNo: HS4708ES

iii. To characterise the cardio-metabolic profile of WRA.,ii. To document the risk behaviours and their factors related to these societal beauty perceptions.,i. To document societal beauty perceptions and their determinants.,To understand what, why and how the health-beauty paradox is so deeply entrenched in the culture.,
Uganda 2024-08-26 10:18:37 2027-08-26 Medical and Health Sciences Clinical Trial Degree Award
George William Ddaaki
ID: UNCST-2022-R009216
Exploring perceptions, concerns, and perceived benefits of pregnant women and those intending to become pregnant towards participating in HIV cure research.
REFNo: SS2866ES

a) To identify concerns and perceived benefits among women in south central Uganda regarding their participation in HIV cure studies.
b) To explore the perceptions and attitudes of pregnant women and those intending to become pregnant in south central Uganda towards participating in a study focused on impact of pregnancy on the HIV viral reservoir and HIV cure.

Uganda 2024-08-26 10:14:01 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
Implementing comprehensive malaria surveillance at sentinel sites in Uganda
REFNo: HS4692ES

To monitor geographic and temporal trends in malaria burden and assess the impact of population level control interventions across a range of epidemiological settings in Uganda.
Uganda 2024-08-26 10:12:47 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRANCIS KIBIRIGE
ID:
GENDER REFORMS AND POLITICAL SYSTEMS IN UGANDA
REFNo: SS2985ES

The broad objective is to put in context the emerging gender programming reforms in Uganda, particularly the persistent narrative that despite the success in policies that promote women in governance, leadership and employment roles, women voices continue to lag behind.

As a secondary objective, the survey also seeks to increase our understanding of how physical and psychological violence targeting political candidates impacts adult Ugandans’ willingness to engage in electoral politics.


Uganda 2024-08-22 16:38:35 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Irene Mutuzo Esther
ID:
Usability Context and Adoption of Human Capital Management Systems in Ugandan Public Universities: Application of the Unified Theory of Acceptance and Use of Technology
REFNo: SS2972ES

Purpose
This study aims to investigate the influence of usability context on the adoption of HCMS in Ugandan Public Universities by using variables from Venkatesh et al.’s (2003) UTAUT theory.

Objectives
The study will focus on the following objectives:
1. To investigate the influence of performance expectancy on Ugandan public university staff behaviour intention to adopt HCMS.
2. To assess the influence of effort expectancy on Ugandan public university staff behaviour intention to adopt HCMS.
3. To investigate the influence of social influence on Ugandan public university staff behaviour intention to adopt HCMS.
4. To examine the influence of facilitating conditions on Ugandan public university staff’s actual use of HCMS.
5. To investigate the influence of Ugandan public university staff behaviour intention on their actual use of HCMS.
6. To investigate the moderating effect of user background characteristics (gender, voluntariness of use, age, and experience) on the relationship between usability context constructs and the adoption of HCMS among Ugandan public university staff.

Research Questions
The study will focus on the following research questions:
1. What are the obstacles impeding the adoption of HCMS in Ugandan public universities, and how can they be addressed?
2. What are the enabling factors facilitating the adoption of HCMS in Ugandan public universities, and how can they be enhanced?

Uganda 2024-08-22 16:35:54 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
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