Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jackson Orem
ID: UNCST-2021-R012016
 AMC-104, Feasibility study of ocular surface squamous neoplasia (OSSN) surgical excision in people living with HIV in sub-Saharan Africa (SSA)
REFNo: HS2366ES

To assess the feasibility of conducting multi-center prospective studies on surgical excision of suspected OSSN lesions in SSA in people living with HIV/AIDS (PLWHA).,
 Uganda 2022-10-28 13:28:27 2025-10-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clovice Kankya
ID: UNCST-2020-R010154
 Capacitating One Health in Eastern and Southern Africa (COHESA)
REFNo: SS1482ES

To understand One Health performance, capacity, and bottlenecks within Uganda,To understand Current One Health Research and Innovation within Uganda,To understand One Health challenges, gaps and capacities within Uganda,
 Uganda 2022-10-27 9:26:54 2025-10-27 Social Science and Humanities Clinical Trial Non-degree Award
EDITH  NAKKU-JOLOBA NAKKU
ID: UNCST-2021-R013931
 MULT-COUNTRY AETIOLOGY OF GENITAL ULCER STUDY
REFNo: HS2498ES

To determine the prevalence of other sexually transmitted infections in individuals with GUD,To assess the Aetiology of genital ulcer diseases in Low and Middle Income Countries.,
 Uganda 2022-10-27 7:52:03 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 STANDARD i-Q COVID-19 Ag Home Test - Laymen study including Usability.
REFNo: HS2511ES

The objective of this laymen study is to establish the usability of the STANDARD i-Q COVID-19 Ag Home Test in a self-testing environment. More specifically, the study will assess whether the instructions for use and labels are clear and understandable and whether the test can be performed correctly by laypersons.,
 Uganda 2022-10-27 7:48:55 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Kibuuka Musoke
ID: UNCST-2021-R011749
 Survey Protocol Zone of Influence Survey Uganda 2022 Feed the Future Phase Two Zone of Influence and Resilience Focus Zone Midline Indicator Assessment
REFNo: A232ES

The Midline Survey will collect primary data to generate estimates for a total of 25 indicators—14 Feed the Future P2-ZOI indicators, plus a new indicator on water security, and 10 RFZ indicators, which will only be collected in the RFZ. ,
 Uganda 2022-10-27 7:38:03 2025-10-27 Agricultural Sciences Non-Clinical Trial Non-degree Award
David Musoke
ID:
Experiences of Village Taskforce members and Community Health Workers in COVID-19 prevention and control in Uganda
REFNo: HS2502ES

To assess the experiences of village task force members and community health workers (CHWs) in response to COVID-19 so as to provide information to strengthen community response to the pandemic in Uganda.
Uganda 2022-10-27 7:35:53 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clara HOZER
ID: UNCST-2022-R010004
 Inter-individual variation in sleep strategies and consequences for fitness and cognition in wild chimpanzees (Pan troglodytes)
REFNo: NS433ES

- To assess whether chimpanzees display inter-individual variation in sleep strategies
- To determine if these strategies are driven by endogenous and social factors
- To explore if these sleep strategies have specific fitness consequences
- To investigate if these sleep strategies are in a trade-off relation with cognitive performance

 France 2022-10-27 7:33:37 2025-10-27 Natural Sciences Non-Clinical Trial Degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
 Feasibility, Usability and Acceptability of stool-based qPCR to diagnose TB in children aged up to 8-years and HIV- positive adults in Mozambique, Eswatini and Uganda: a qualitative study
REFNo: SS1492ES

To identify cultural, socioeconomic and health system barriers and facilitators to the diagnostic tool’s implementation and uptake,To assess healthcare professionals’ perception of usefulness and applicability and related factors,To assess patients’ compliance and satisfaction with the intervention,To assess the participants’ (caretakers and PLWHA)/health professionals’ interpretation of a procedure involving stool collection for TB diagnosis in the light of current information, education communication messages regarding TB transmission,To describe participants’ views on, experiences with, and reactions towards the intervention,To explore participant’s perceptions and attitudes regarding TB in general and diagnosis in particular,To assess the feasibility of stool-based TB diagnostics from the healthcare professionals, patients and caregiver’s perspective in Uganda, Eswatini and Mozambique,
 Uganda 2022-10-27 7:29:40 2025-10-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paul Kiptis Kipyator
ID:
PITYRIASIS ROSEA: PREVALENCE, CLINICAL VARIANTS, AND DERMOSCOPIC FEATURES AMONG PATIENTS ATTENDING THE SKIN CLINIC AT MBARARA REGIONAL REFERRAL HOSPITAL, UGANDA
REFNo: NS435ES

To describe the dermoscopic features of Pityriasis rosea at MRRH Skin clinic.,To describe the clinical variants of Pityriasis rosea at MRRH Skin clinic.,To determine the prevalence of Pityriasis rosea at MRRH Skin clinic.,To determine the prevalence, clinical variants, and dermoscopic features of Pityriasis rosea among patients attending the Skin clinic at MRRH.,
 Kenya 2022-10-27 7:26:09 2025-10-27 Natural Sciences Non-Clinical Trial Degree Award
Allison Ross
ID:
Behavioral Nudges to Encourage Appropriate Antibiotic Use Among Health Professionals in Uganda
REFNo: HS2429ES

Collect immediate post-intervention and follow up data to analyze and assess the short- and medium-term impact of the behavioral intervention. Implement the behavioral intervention developed in Phase II to impact prescribing behaviors. Develop a culturally appropriate behavioral intervention based on findings from Phase I. Gain an improved understanding of the cultural context around prescriptions in Ugandan hospitals to inform intervention development. Additionally, collect baseline data on prescribing behaviors among staff. Increase adherence to national antibiotic prescribing guidelines among hospital-based health care providers in Uganda by implementing a behavioral “nudge” intervention, contributing to the containment of AMR in the country.
 USA 2022-10-27 7:21:19 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jordan Lwanga Byekwaso
ID:
Towards an inclusive higher education for non-traditional students in Uganda
REFNo: SS1458ES

4) To develop a model of teaching-learning strategies that Makerere University can use to support learners to succeed in rapidly changing learning and working environments,3) To explain the different opportunities that the enrollment and participation of NTS at Makerere University provide to re-align HE systems and practices for inclusivity,2) To explain the different understandings of the central meaning of NTS’s return for higher education at Makerere University ,1) To establish an understanding of what Makerere University conceptualises as the target and purpose of widening access routes for its admission for undergraduate studies,
 Uganda 2022-10-25 5:14:45 2025-10-25 Social Science and Humanities Non-Clinical Trial Degree Award
Derrick Mimbe Emmanuel
ID:
Evaluate the existing Digital Tools to support COVID-19 response in Uganda
REFNo: SIR140ES

Provide recommendation on performance and use of existing digital tools including ODK, mTrac, and RDS applications to improve results dispatching, contact tracing, and case reporting., Evaluate existing COVID-19 digital tools to understand their core determinants and their operational usability and acceptability among key end-users to improve the COVID-19 response in Uganda.,
 Uganda 2022-10-25 5:13:07 2025-10-25 Engineering and Technology Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Extension of SEARCH SAPPHIRE Dynamic Choice Prevention Study
REFNo: HS2447ES

To compare biomedical prevention coverage achieved using a Dynamic prevention model that includes a patient-centered CAB-LA delivery intervention to biomedical prevention coverage under the standard of care over 48 weeks.

Secondary Objectives: To determine the reach, effectiveness, adoption, implementation and maintenance of a patient-centered CAB-LA program embedded in 3 ongoing trials in the setting of antenatal clinic, outpatient clinic, and community.

Tertiary Objectives: To evaluate change in knowledge, awareness and acceptability/satisfaction at the staff and provider level with CAB-LA before and after provider and staff training and education in CAB-LA with patient-centered delivery model.


 Uganda 2022-10-25 15:31:11 2025-10-25 Medical and Health Sciences Clinical Trial Non-degree Award
Terence Odoch
ID: UNCST-2022-R010584
 AN EXPLORATIVE INVESTIGATION TO IDENTIFY ECONOMIC, BEHAVIOURAL, SOCIO-CULTURAL AND GENDER-BASED RISK FACTORS FOR DISEASE SPILLOVER AT BAT-HUMAN INTERFACE IN BUNDIBUGYO, UGANDA
REFNo: HS2472ES

To explore the community behavioural, socio-cultural and gender-based factors that contribute to increased risk of human-bat interaction,To describe local knowledge and beliefs about bat species, risks, and benefits,To explore and document economic, behavioral, socio-cultural and gender-based risk factors that expose and enhance spillover of zoonotic disease pathogens at bat-human interface,To determine the level of bat-human interaction in Bundibugyo district by age and gender,
 Uganda 2022-10-25 14:56:35 2025-10-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Angelina Kakooza-Mwesige
ID: UNCST-2020-R014529
 Epilepsy in Uganda: Clinical characterization and co-morbidities, their relation to stigma among adolescents and impact of a community-based engagement program. (AWE Change project) REF: TASO-2022-102
REFNo: HS2421ES

1.TO CLINICALLY CHARACTERIZE EPILEPSY AND ITS IMPACTS AMONG CHILDREN AND ADULT CASES IN UGANDA. 2.DESCRIBE THE MAGNITUDE, DRIVERS, AND IMPACT OF EPILEPSY-RELATED STIGMA ON ADOLESCENTS IN UGANDA. 3.TO CO-CREATE AND EVALUATE THE IMPACT OF A COMMUNITY-BASED ENGAGEMENT PROGRAM TO REDUCE STIGMA ON EPILEPSY AMONG ADOLESCENTS IN UGANDA.
 Uganda 2022-10-25 14:54:28 2025-10-25 Medical and Health Sciences Clinical Trial Non-degree Award
JULIET SSEMATIMBA
ID:
INDIGENOUS SALT MAKING TECHNOLOGY AT KIBIRO SALT GARDENS IN BUNYORO 1894-2015.
REFNo: SS1450ES

The main objective of the study is to investigate and discuss the historical trends of indigenous salt making technology , its persistence and how that shapes the gender relation at kibiro salt gardens.
 Uganda 2022-10-21 17:04:00 2025-10-21 Social Science and Humanities Non-Clinical Trial Degree Award
Jemimah Kyeyune Kiboss
ID: UNCST-2021-R013163
 Prevalence of Metabolic Syndrome and Associated Factors Among Corporate Company Employees in Uganda
REFNo: HS2098ES

III. To determine the lifestyle factors associated with metabolic syndrome among corporate company employees in Kampala.,II. To identify individual factors associated with metabolic syndrome among corporate company employees in Kampala.,I. To assess the prevalence of metabolic syndrome among corporate employees in Kampala.,The main aim of this study will be to evaluate the prevalence of metabolic syndrome and its associated factors among corporate company employees in Kampala, Uganda.,I. To assess the prevalence of metabolic syndrome among corporate employees in Kampala. II. To identify individual factors associated with metabolic syndrome among corporate company employees in Kampala. III. To determine the lifestyle factors associated with metabolic syndrome among corporate company employees in Kampala.,
 Kenya 2022-10-21 17:01:28 2025-10-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick Opondo
ID: UNCST-2022-R010446
 A Monitoring and Evaluation of Managing Animal Health and Acaricides for a Better Africa (MAHABA): A landscaping study in Uganda
REFNo: A233ES

Assess protocols selected in controlling ticks and tickborne diseases, Assess acaricide availability to the farmers ,Assess extent of farmer observed acaricide resistance and treatment failures, Determine farm size and management systems of farmers, Determine the number and proportion of farmers using acaricides ,Assess other production constraints among farmers ,Assess the cost controlling of ticks and tick borne diseases among farmers, Assess farmers practices, knowledge, perceptions, attitudes and challenges on use of acaricide products for cattle in the control of Ticks and tickborne diseases in selected districts of Uganda with high burden of ticks and tickborne diseases, Assess the role of gender in ticks and tick borne disease management, Assess opportunities for developing new routes for communication, Determine sources of information on acaricides, ticks and tickborne diseases
 Uganda 2022-10-21 14:11:50 2025-10-21 Agricultural Sciences Non-Clinical Trial Non-degree Award
Fredrick Kabi
ID:
EVALUATION OF THE SAFETY, EFFICACY AND EFFECTIVENESS OF THE SUBOLESIN BASED ANTI-TICK VACCINE: A RANDOMISED DOUBLE BLINDED MULTI-SITE CONFINED FIELD TRIAL
REFNo: A191ES

OVERALL OBJECTIVE
Evaluation of the Safety, Efficacy and Effectiveness of Subolesin based Anti-tick Vaccine for control of ticks naturally infesting different cattle breeds under confined field conditions in Uganda.

SPECIFIC OBJECTIVES
I. To determine the safety of the injectable Subolesin based Anti-tick vaccine for control of tick infestations under natural confined field conditions.
II. To determine the efficacy of the injectable Subolesin based Anti-tick vaccine for control of tick infestations under natural confined field conditions.
III. To determine the effectiveness of the injectable Subolesin based Anti-tick vaccine for control of tick infestations under natural confined field conditions.

 Uganda 2022-10-21 12:58:12 2025-10-21 Agricultural Sciences Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 A Phase Ib trial to evaluate the safety and immunogenicity of R21/Matrix-MTM in African children living with HIV.
REFNo: HS2496ES

Primary objective a) To assess the safety and reactogenicity profile of the malaria vaccine candidate R21/Matrix-MTM in 5-36-month-old African children living with HIV Secondary objectives a) To assess the humoral immunogenicity of R21/Matrix- MTM in 5-36-month-old African children, comparing children living with HIV with HIV negative children b) To assess the impact of vaccination on HIV reservoir c) To assess whether increasing age and nadir CD4 count are associated with immunogenicity of R21/Matrix-MTM in 5-36- month-old African children living with HIV Tertiary objectives a) To assess the immunogenicity profile of R21/Matrix-MTM in 5- 36-month-old African children, comparing children living with HIV with HIV negative children
 Uganda 2022-10-20 18:13:49 2025-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
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