Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Fred Abila
ID:
PREVALENCE AND RISK FACTORS ASSOCIATED WITH PLASMODIUM FALCIPARUM HISTIDINE-RICH PROTEINS 2/3 GENOMIC LOCI DELETIONS IN LANGO AND ACHOLI SUB-REGIONS, NORTHERN UGANDA
REFNo: HS4067ES

3. To determine the risk factors associated with PfHRP2/3 gene deletions among patients with confirmed P. falciparum malaria cases in selected health facilities in the sub regions.,2. To determine the parasite density among patients with confirmed PfHRP2/3 genes deletion in selected health facilities in Lango and Acholi Sub region, Northern Uganda,1. To determine the prevalence of suspected false-negative PfHRP2 RDT results and PfHRP2/3 genes deletion among patients with confirmed P. falciparum malaria cases in health facilities in Lango and Acholi sub regions, Northern Uganda.,To assess the prevalence and factors associated with PfHRP23 gene deletions leading to false negative PfHRP2/3 RDT results among patients with confirmed malaria in selected health facilities in Lango and Acholi Sub regions, Northern Uganda,
 Uganda 2024-06-21 18:01:59 2027-06-21 Medical and Health Sciences Non-Clinical Trial Degree Award
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
 Tuberculosis (TB) Differentiated Service Delivery (DSD) approaches to support continuity of essential services during COVID and beyond in Uganda
REFNo: HS3122ES

5. To improve IPT coverage among children <5 years who are contacts of index TB clients in select health facilities in Kampala and Soroti regions,4. To improve identification of contacts of index TB clients in select health facilities in Kampala and Soroti regions, and improve their access to comprehensive diagnostic workup ,3. To improve TB treatment success (lower death rates, lower interruption rates, higher completion/cure rates) through implementation of DSD approaches in select health facilities in Kampala and Soroti regions ,2. To improve TB treatment initiation for newly identified TB cases through timely commencement of TB treatment in select health facilities in Kampala and Soroti regions ,1. To design and implement DSD models, to evaluate the models’ ability to effectively provide TPT and TB treatment, and to inform national TB/TPT DSD guidelines,To implement and evaluate innovative approaches and client care models to improve health care access, increase TB case detection and strengthen TB service delivery through DSD models. ,
 Uganda 2024-06-21 18:00:08 2027-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charles Mukundane Godfrey
ID:
Gendered Power Relations, Food Production and Socioeconomic Livelihoods of Female Headed Households in Ankole Region
REFNo: SS2293ES

1. To examine how gendered power relations has affected food production among female headed households in Ankole Region. 2. To determine the mediating effect of food production on socioeconomic livelihoods of female headed households in Ankole Region. 3. To examine how gendered power relations has affected socioeconomic livelihoods of female headed households in Ankole Region.,To examine how gendered power relations influence food production and socioeconomic livelihoods of female headed households in Ankole Region.,
 Uganda 2024-06-21 17:58:16 2027-06-21 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Katumba
ID:
A Machine Learning-aided Platform for Point-of-Care Pregnancy Risk Assessment from 2D Ultrasound
REFNo: HS4144ES

1. To develop a predictive ML model based on ultrasound, clinical, and demographic data to categorize pregnancy risk and enable the community health worker to make appropriate and timely intervention recommendations.
2. To integrate the ML model in the image processing pipeline of a hand-held portable ultrasound system.
3. To pilot and evaluate the efficacy of the predictive and diagnostic models in managing high-risk pregnancies.

 Uganda 2024-06-21 17:54:02 2027-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martin Bikorwomuhangi
ID:
INCIDENCE, INDICATIONS AND SHORT-TERM OUTCOMES OF NON-CONVENTIONAL INTRA-ABDOMINAL DRAINS AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: SS2689ES

4.To determine the association between different types of non-conventional intra-abdominal drains and short-term outcomes among patients who undergo intra-abdominal surgery at Surgical ward MRRH,3.To describe the different short-term outcomes among patients with non-conventional intra-abdominal drains among patients who undergo intra-abdominal surgery at Surgical ward MRRH,2.To document the various indications of non-conventional intra-abdominal drains among patients who undergo intra-abdominal surgery at Surgical ward MRRH,1.To determine the incidence of non-conventional intra-abdominal drains among patients who undergo intra-abdominal surgery at Surgical ward MRRH,To determine the incidence, indications and short-term outcomes of non-conventional intra-abdominal drains among patients who undergo intra-abdominal surgery at Surgical ward MRRH,
 Uganda 2024-06-21 17:53:08 2027-06-21 Social Science and Humanities Non-Clinical Trial Degree Award
Stevens Bechange
ID: UNCST-2022-R009190
 Eye Health Systems Assessment – Uganda
REFNo: HS4368ES

Examine how the above components of the eye health system recognise and address the needs of groups identified as vulnerable to exclusion from services,Assess the available eye care infrastructure,Assess the information system for eye health,Determine available medical products, vaccines and technologies for eye care,Determine available human resources for eye health,Describe eye care service delivery ,Assess the health financing mechanisms in operation,Describe the governance and leadership function ,The overall objective of this study is to examine and document the strengths and weaknesses of all components of the eye health care delivery system and health system linkages – thus providing a basis for targeted programmatic work to strengthen the eye health systems infrastructure and improving outcomes for eye conditions in Uganda.,
 Uganda 2024-06-21 17:51:54 2027-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
George Kasule William
ID: UNCST-2023-R006891
 EVALUATION OF NON-SPUTUM-BASED DIAGNOSTICS AND BIOMARKERS FOR DETECTION OF M. TUBERCULOSIS AMONG CHILDREN AND PEOPLE LIVING WITH HIV
REFNo: HS4344ES

To assess literature review of Mycobacterium tuberculosis biomarkers in non-invasively collected non-sputum samples of the Oral-Gut and Nasal pharynx parts of humans. To determine the diagnostic performance of novel stool-based biomarkers for detecting tuberculosis in children and among PLHIV using stool samples.To determine the diagnostic performance of breath-based biomarkers for detecting tuberculosis in children and among PLHIV.To determine the diagnostic performance of novel urine-based biomarkers for detecting tuberculosis in children and among PLHIV.To explore health workers’ and policymakers’ perceptions on the use of non-sputum-based assays for detecting tuberculosis in children and among PLHIV in Uganda.
 Uganda 2024-06-21 17:50:21 2027-06-21 Medical and Health Sciences Non-Clinical Trial Degree Award
Rose Nabirye Chalo
ID: UNCST-2020-R014645
 DEVELOPMENT OF AN INTER-PROFESSIONAL EDUCATIONAL PROGRAMME FOR THE ASSESSMENT OF MENTAL HEALTH OF PREGNANT TEENAGERS
REFNo: SS2691ES

The proposed project seeks to promote inter-professional education by developing an educational programme that will be used for inter-professional training of students in the health professions on the mental health assessment of pregnant teenagers.,
 Uganda 2024-06-21 17:48:53 2027-06-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Daniel Iraguha Ndungutse
ID: UNCST-2024-R003686
 DETECTION OF PAROXYSMAL ATRIAL FIBRILLATION AMONG RHEUMATIC HEART DISEASE REGISTRY PATIENTS AT THE UGANDA HEART INSTITUTE, A PREVENTIVE STRATEGY AGAINST STROKE
REFNo: HS4389ES

• To determine the prevalence of paroxysmal
atrial fibrillation using ambulatory ECG
monitoring among participants with severe
RHD in the Uganda Heart registry
• To determine factors associated with
paroxysmal atrial fibrillation among
participants with severe RHD in the Uganda
RHD registry

 Uganda 2024-06-21 17:47:52 2027-06-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
 Integrating Tuberculosis Treatment into Community Pharmacies to improve TB/HIV outcomes in Uganda: the Community Pharmacy Tuberculosis Treatment (COPHAT) study
REFNo: HS4397ES

To evaluate the implementation and preliminary effectiveness of integrating TB treatment into community pharmacies among people with TB/HIV.,To adapt a person-centered strategy for integrating TB treatment into community pharmacies using a human-centered design methodology.,To explore the barriers and facilitators to integrating TB treatment into community pharmacies among people with TB/HIV.,The main objective of this Community Pharmacy Tuberculosis Treatment (COPHAT) study is to develop and pilot an implementation strategy focused on integrating TB treatment into community pharmacies among people with TB/HIV in Kampala, Uganda. ,
 Uganda 2024-06-21 17:46:35 2027-06-21 Medical and Health Sciences Clinical Trial Non-degree Award
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