Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
 Maternal Ultrasound Prospective Observational Study for Machine Leaning Model Training
REFNo: HS6020ES

1. Collect ultrasound data from pregnant and non-pregnant individuals presenting at Kawempe national referral hospital. 2. Use the collected data and ultrasound images to train and validate MOBUS algorithms.,
 Uganda 2025-07-04 14:00:42 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID: UNCST-2021-R011663
 SEROPREVALENCE OF MARBURG VIRUS INFECTION AND OTHER WHO-PRIORITY PATHOGEN IN THREE (3) COUNTRIES IN AFRICA
REFNo: HS6241ES

Primary objectives 1.To assess previous exposure to Marburg Virus (MARV) Infection in the general population in three (3) African countries, determined by measuring circulating IgG antibodies.
2.To estimate MARV force of infection (FOI) in the three (3) African countries. 3.To develop a platform for the implementation of seroprevalence of WHO priority pathogens in Africa Secondary objectives 1.
To characterize age-specific and gender-specific seroprevalence trends. 2.To determine risk factors associated with prior infection with MARV in the three (3) African countries. 3. To assess host genetic factors including single nucleotide polymorphism (SNP) of candidate genes that could be associated with susceptibility/protection from infection with MARV and other outbreak-worthy pathogens. 4.To estimate the seroprevalence of other WHO priority filovirus pathogens, including EBOV, SUDV, BDBV, TAFV, RAVN, etc. Exploratory objectives 1.To evaluate potential cross-reactivity of MARV IgG with other filoviruses. 2.To investigate neutralizing capacity of human monoclonal antibodies against MARV
Uganda 2025-07-04 13:58:59 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ERIC WOBUDEYA
ID: UNCST-2019-R001047
 Paediatric Post-TB home-based Pulmonary Rehabilitation Feasibility Study
REFNo: HS6222ES

Primary objective:
• To explore the feasibility of implementing a 6-week at home pulmonary rehabilitation program in children with diagnosed with PTLD, including measures of participant retention and adherence.

Secondary objectives:
• To evaluate the change in health-related quality of life following the pulmonary rehabilitation intervention.
• To assess the change in exercise capacity following the 6-week pulmonary rehabilitation intervention.
• To explore the experiences and perceptions of children, caregivers, and healthcare providers related to the acceptability and feasibility of the pulmonary rehabilitation program

 Uganda 2025-07-04 13:57:06 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tarekegn Abeku Abose
ID: UNCST-2023-R005864
 improving early warning and control of mosquito-borne disease outbreaks caused by extreme weather in Uganda
REFNo: HS5162ES

Main Objective
1. The project’s main objective is to strengthen the health system capacity in Uganda for improved early warning and rapid control of mosquito-borne disease outbreaks caused by extreme weather events, focussing on malaria RVF and YF.
Specific Objectives
1. 1. To document past mosquito-borne disease outbreaks in Uganda and analyse their association with extreme weather
2. 2. To develop and validate a risk index and early warning models to forecast the outbreaks
3. 3. To develop a platform that maps risks and generates predictions continuously, where real-time surveillance data feed into, for routine use by disease control programmes
4. 4. To develop an outbreak preparedness and response plan for various risk scenarios
5. 5. To facilitate adoption and use of the system
6. 6. To engage communities in the research activities
 UK 2025-07-04 13:55:42 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Kiweewa
ID: UNCST-2020-R014929
 Longitudinal observation of cardiovascular diseases among people living with HIV in Lango Sub-region, Northern-Uganda.
REFNo: HS5900ES

Primary Objective
Assess the burden, risks and correlates of cardiovascular diseases (CVD) among people living with HIV (PLWH) in Northern Uganda to inform strategies for prevention, care and treatment in Sub-Saharan Africa.
The primary objective will be achieved through several secondary an explorative objective themed around forming a comprehensive understanding of the epidemiological, clinical, socio-behavioural, immunological, genetic, and microbiome-related factors influencing CVD among PLWH. The secondary and exploratory objectives are detailed in the attached protocol
 Uganda 2025-07-04 13:54:27 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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