Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
Impact of Unmet Needs on the Health Outcomes of Cancer Patients and their Family Caregivers in Uganda
REFNo: HS4842ES

1. What are the unmet needs of adult cancer patients (ACPs) with solid tumors in Uganda?
2. What are the unmet needs of family caregivers (FCs) of ACPs with solid tumors in Uganda?
3. What is the relationship between unmet needs and health outcomes (depressive symptoms, anxiety, and quality of life) of ACPs with solid tumors?
4. What is the relationship between unmet needs and health outcomes (depressive symptoms, anxiety, and quality of life) of FCs?

Uganda 2024-09-10 9:51:03 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
Dynamics of host immunity in the setting of malaria control interventions.
REFNo: HS4815ES

1. To quantify longitudinal changes in clinical phenotypes of
immunity by exploring relationships between key malaria metrics.
2. To comprehensively and longitudinally profile antibody immune
responses in individuals living in an area with or without sustained
IRS.
3. To profile the innate and adaptive cellular immune response
comprehensively and longitudinally in individuals living in an area
with or without sustained IRS.
Uganda 2024-09-10 18:00:40 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John William Okello
ID: UNCST-2024-R004558
Learning Entrepreneurship and Agriculture Practically - LEAP Programme
REFNo: SS3039ES

The longitudinal follow-up study will measure and analyse the self-efficacy in teaching of agriculture and entrepreneurship student-teachers/instructors and newly qualified teachers/instructors (NQTs/NQIs) over time – in particular, their self-efficacy in using gender responsive project-based learning (PBL), study and career guidance (SCG) and, in the case of instructors also work-based learning (WBL) (internships) in collaboration with the agri-WoW. This is one of the core outcomes of LEAP interventions with NTC Mubende, NTC Unyama, NICA and Gulu University related to their school practice and industrial training trajectories. Besides self-efficacy, career commitment to teaching will also be measured, to explore its’ interplays with self-efficacy.,
Uganda 2024-09-10 12:36:56 2027-09-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Mutiu Bakare Mutiu
ID: UNCST-2024-R004123
AN OPTIMIZED ANFIS WITH GENE EXPRESSION PROGRAMMING BASED DEMAND SIDE ENERGY MANAGEMENT CONTROLLER WITH GRID AND SOLAR PV/BATTERY ENERGY SOURCES
REFNo: SIR393ES

V. To compare and validate the models developed in II and III using ANFIS and HOMER software.,IV. Assessment of the optimal system configuration to determine the techno-economic analysis to quantify Solar PV to save the cost of Energy of the proposed system configuration.,III. To develop a GEP-ANFIS energy management scheme for operation of industrial loads while ensuring maximum user comfort without waiting time;,II. To use (GEP-ANFIS) model and historical load data to accurately forecast the energy consumption and renewable energy generation;,I. To integrate MPPT Algorithms into the system design,The aim of this research is to examine the potential of applying optimization-based TOU DSM in the industrial sector by utilizing grid-connected solar and battery energy sources to reduce peak electricity demands as well as the costs associated with annual electricity consumption,
Nigeria 2024-09-10 11:07:47 2027-09-10 Engineering and Technology Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Assessing the reliability and test performance of malaria rapid diagnostic tests after expiration.
REFNo: HS4760ES

AIM 1: Estimate the reliability, defined as the proportion of malaria RDTs that function (i.e., appearance of control band) at various time-points up to one year after expiration. AIM 2: Determine the test performance (e.g., sensitivity, specificity) of malaria RDTs for the diagnosis of P. falciparum malaria at various time-points up to one year after expiration compared to non-expired RDTs and routine light microscopy performed in parallel. AIM 3: Estimate the time-to-negativity after treatment among participants with a positive RDT on enrollment.,The primary objective of the proposed project is to evaluate the performance of malaria RDTs at various states of expiration (e.g., 1-, 2-, 3-months post-expiration) compared to non-expired RDTs in routine use. If our hypothesis is correct, our results may facilitate (i) use beyond the stated expiration and/or production of RDTs with longer expiration periods, both of which could reduce medical waste. ,
Uganda 2024-09-10 11:02:24 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MICHAEL KAWOOYA GRACE
ID: UNCST-2020-R014672
The African Breast Imaging Dataset for Equitable Cancer Care (The ABreast Data set)
REFNo: HS4709ES

1. To train community health workers to conduct breast examination using hand held ultrasound machines in the community
2. To develop the first publicly available expert-labelled ultrasound imaging data with mammograms, a wealth of clinical profiles, and where available biopsy pathology data.
3. Introduce the Abreast Challenge, as a new image segmentation grand challengevii at the 2024 Medical Image Computing and Computer Assisted Intervention Society (MICCAI) annual meeting, happening for the first time in Africa (Morocco).
4. Introduce a baseline state of the art (SOTA) model of a deep learning approach for lesion detection of breast lesions on low-cost (also low-resolution) POC-US for wider screening accessibility.
5. Train up to 70 African clinicians and researchers to develop SOTA ML lesion detection methods to ensure that SSA retains a local community of skilled experts who are knowledgeable on how to use ML data to solve local health needs.
Uganda 2024-09-10 10:56:03 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
Evaluating the Impact of DESC Approach: Comparative Quasi-Experimental Study of Community Health Worker Performance in Moyo and Adjumani Districts, West Nile Uganda
REFNo: HS4756ES

1) To evaluate the impact of the DESC Approach on CHW performance metrics, including CHW reporting rates, household visits, health services provided, and engagement in activities.
2) To generate evidence on performance-based pay options to inform policies on CHW compensation at the district level by October 2024
3) To compare CHW performance between intervention (Moyo District) and non-intervention (Adjumani District) areas.
4) To assess the effectiveness of mobile technology utilization, training, and performance-based incentives in enhancing CHW performance.
Uganda 2024-09-10 10:52:55 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JUDITH AWACORACH
ID: UNCST-2024-R004547
GREEN FINANCE INCENTIVES AND SUSTAINABLE LIVELIHOOD OUTCOMES IN UGANDA
REFNo: SS2993ES

To examine the mediating role of competitive advantage of green charcoal value chain in the relationship between Green Finance incentives and sustainable Livelihood outcomes in Uganda,To examine the mediating roles of green charcoal value chain in the relationship between Green Finance incentives and sustainable livelihood outcomes of green charcoal production in Uganda.,To examine the competitiveness of green finance incentive for green charcoal in sustainable livelihood outcomes in Uganda,To assess the contributions of green finance incentives in the green charcoal value chain to enhance sustainable livelihood outcomes in Uganda.,To assess the green finance use in green charcoal production to enhance sustainable livelihood outcomes in Uganda,To assess availability and accessibility of green finance incentives and its contributions to sustainable livelihood outcomes in Uganda,
Uganda 2024-09-10 10:49:52 2027-09-10 Social Science and Humanities Non-Clinical Trial Degree Award
Alison Elliott
ID: UNCST-2023-R006524
OBTAINING SINGLE-CELL LEVEL INSIGHTS INTO THE IMMUNOLOGICAL AND METABOLIC PATHWAYS ASSOCIATED WITH VACCINE HYPO-RESPONSIVENESS [REVERSE]
REFNo: HS4782ES

1. To measure the SARS-CoV-2 antibody response at baseline, 3 months after prime vaccination and 1 month after boost vaccination in European and Ugandan adults. 2. To characterise peripheral blood mononuclear cells (PBMCs) and their response to prime/booster vaccination with the AstraZeneca ChadOx1 nCoV-19 vaccine in European and Ugandan adults using single-cell technologies
UK 2024-09-10 10:45:15 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brandon Maser
ID: UNCST-2024-R005142
Understanding How Policies, Politics, and National Contexts Influence Access to Opioid Medicines in Uganda
REFNo: HS4768ES

1) To elucidate the policy mechanisms that are used by policymakers to govern access to and safe use of opioid medicines in Uganda. 2) To understand how political factors and national context influence the political priority for improving access to opioid medicines within Uganda’s national government’s policy agenda. 3) To understand how political factors and national context influence how governmental, non-governmental, and transnational actors formulate alternative policy options for ensuring access to opioid medicines in Uganda. 4) To understand how policies governing opioid analgesics and those governing OAT have been uniquely influenced by political factors and national contexts during Uganda’s opioid policy reforms.
Canada 2024-09-10 10:26:35 2027-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
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