Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Isaac Ssewanyana
ID: UNCST-2020-R014336
Performance Evaluation of the Alinity m HIV-1 Assay using DBS
REFNo: HS2595ES

• To describe the operational characteristics and ease of use of the assays and their suitability for use in countries with limited infrastructure. ,• To assess the assay’s agreement with cobas HIV-1 Quantitative nucleic acid test for use on the cobas 6800/8800 Systems (Roche Diagnostics GmbH) on clinical specimens, including: o Quantitative assessment of bias, limits of agreement and correlation, o Misclassification above or below the clinical threshold;,The overall objective of the performance evaluation is to evaluate the performance and operational characteristics of Alinity m HIV-1 Assay (using DBS) intended for the quantification of HIV viral load in HIV-infected individuals.,
Uganda 2022-12-12 16:06:22 2025-12-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIET  NAKIGANDA
ID:
Private Sector Malaria Vector Control Scoping in Uganda: A Land Scape Analysis
REFNo: SS1512ES

To understand the public (consumers) perspectives and practices in accessing vector control commodities from the private sector, specifically (enter commodities),3. To identify the capacity and technical challenges that affect the quality of products and services of private sector vector control ,2. To map out the private sector supply chain systems of vector control products from importation to consumption in Uganda.,1. To understand the current regulations governing the quality and product range of imported and locally manufactured vector control commodities,To identify immediate and core gaps in the policies, access, supply, and use of malaria vector control interventions in the private sector so that the NMCD can channel focal interventions to increase access to quality vector control interventions in the private sector. ,
Uganda 2022-12-12 16:00:29 2025-12-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
KENNETH MUGABE
ID: UNCST-2022-R010732
Using lactate testing to improve maternal sepsis identification: a multi-country test accuracy study: LACTate in mATernal sEpsis
REFNo: HS2589ES

VI. Conduct a validation study of an alternative reference standard in which the SOFA score is modified to incorporate maternity specific ranges for creatinine and platelet concentration.,V. Exploratory analysis will examine the effect of adjusting the threshold values for both vital sign and lactate assessment on the sensitivity and specificity of the index tests.,IV. To explore if the test accuracy of lactate in addition to maternal vital sign monitoring alone varies by the pre-specified subgroups of pregnancy status (pregnant or post-delivery (including abortion or miscarriage)) and recruitment country.,III. To explore if baseline venous lactate, in addition to vital sign measurements, improves prediction of severe morbidity and mortality from infection.,II. To assess short-term predictive value of lactate testing, by comparing the baseline index test with 24-hour reference standard, in those without sepsis at baseline.,I. Immediate diagnostic value of lactate testing by comparing the baseline index test with baseline reference standard.,Determine the diagnostic accuracy of maternal venous lactate measurement in addition to maternal vital sign thresholds, in maternal sepsis in low-resource health facility settings in Malawi, Uganda and Pakistan.,
Uganda 2022-12-12 15:55:39 2025-12-12 Medical and Health Sciences Clinical Trial Non-degree Award
Amrei von Braun
ID:
RAPID SURVEILLANCE OF MOLECULAR MARKERS FOR ARTEMISININ RESISTANCE
REFNo: HS2546ES

To describe the type and prevalence of Plasmodium falciparum mutations conferring artemisinin resistance
Germany 2022-12-12 15:42:25 2025-12-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BEATRICE KATUSIIME
ID:
UNDERSTANDING THE COMMUNITY’S AND RESEARCH PARTICIPANTS’ PERCEPTIONS AND KNOWLEDGE OF VULNERABILITY IN RESEARCH: A QUALITATIVE STUDY IN UGANDA
REFNo: SS1495ES

3. To examine the determinants of vulnerability in health research conducted in Mbarara city,2. To explore the perception of research participants regarding vulnerability in health research in Mbarara city,1. To assess the community’s understanding of vulnerability in health research in Mbarara city,To describe community and research participants’ perceptions and knowledge of vulnerability in health research in Mbarara city,
Uganda 2022-12-12 15:32:51 2025-12-12 Social Science and Humanities Non-Clinical Trial Degree Award
YUKO NAKANO
ID:
How Effective is Formalization of Land Rental Agreement for Dispute Prevention? Evidence from Randomized Control Trial in Uganda’s Refugee Camp
REFNo: SS1540ES

To investigate if formal land rental agreement increase refugees’ income,To investigate if the access to the land rental market increased by the formalization of land rental transactions,To investigate if formal land rental agreement reduce conflicts between refugees and local Ugandans,
Japan 2022-12-12 15:26:49 2025-12-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Performance Evaluation of the Alinity m HIV-1 Assay using DBS for Detection of HIV-1 in Infants.
REFNo: HS2586ES

To verify the performance (sensitivity and specificity) of the Alinity m HIV-1 Qualitative Test against routine Cobas Ampliprep/Taqman HIV-1 Qualitative Test Version 2.0 (DBS)- for early diagnosis of HIV-1 in exposed infants. ,
Uganda 2022-12-12 15:23:01 2025-12-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brian Kiira Alex
ID:
Emerging Ethics and Human Rights Issues in the Digitization of Population Register Systems
REFNo: SS1383ES

1. To nurture a new generation of scholars and practitioners via direct mentoring from senior scholars and experienced practitioners in the field, immersion into academic, policy and practitioner networks, debates and institutions, exposure and visibility through publications and communications based in the global South. 2. To support active collaboration between fellows as well as between IUSSP, WiSER, ISER and IIGH-USC. 3. To nurture a generation of scholars who will challenge experienced practitioners, senior scholars and established systems to consider new perspectives, rethink established assumptions and question dominant paradigms for population register systems. 4. To facilitate stronger engagement by population scientists on contemporary issues and support interdisciplinary collaboration with established scholars from other disciplines and early career researchers and practitioners around ethics and human rights in the digitization of population register systems.
Uganda 2022-12-09 12:35:52 2025-12-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
FRED SEMITALA COLLINS
ID: UNCST-2020-R014096
Differentiated Services Delivery Outcomes in Uganda: Facilitators, barriers, and qualitative systems mapping.
REFNo: HS2497ES

To evaluate the performance and quality of DSD models in the delivery of HIV/TB services in Uganda.
Specific Objectives:
1. To assess the performance and Quality of intensive and less intensive DSD models of care for HIV/TB TB services in Uganda.
2. To elicit stakeholders’ perspectives on facilitators of and barriers to improved DSD performance in Uganda.

3. To identify system elements (systems mapping) and determine how their relationships in health care affect both positively and negatively the performance of DSD service delivery in Uganda.

Uganda 2022-12-08 15:05:56 2025-12-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Mafigiri Kaawa
ID: UNCST-2019-R001276
Rapid Anthropological Study in Districts Affected by Ebola (Sudan Strain) in Uganda
REFNo: SS1542ES

The general objective of this study is to explore the socio-cultural construction of the drivers of the current Ebola virus disease (EBV) transmission and community resistance to Ebola response strategies in Uganda
Uganda 2022-12-08 13:08:41 2025-12-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Barasa Chemutai Mercy
ID:
LEVERAGING TEACHER CONCERNS IN CURRICULUM REFORM: A MIXED METHODS STUDY OF SELECTED GOVERNMENT SCHOOLS IN UGANDA
REFNo: SS1541ES

iv. To explain the relationships between curriculum reform strategies, teacher concerns and the quality of implementation of the LSC using themes emerging from interviews with teachers, school administrators, and national education officials. ,iii. To compare the influence of support strategies by school administrators on the nature of teacher concerns and the quality of implementation of the curriculum in three different school contexts.,ii. To determine the extent to which teacher concerns mediate the relationship between the curriculum reform strategies and the quality of implementation of the CBC.,i. To investigate the nature of the concerns of Ugandan secondary school teachers about the CBC.,to determine the role of teacher concerns in the lower secondary curriculum reform process in Uganda by investigating the relationships between the strategies of curriculum reform, the concerns of teachers implementing the reform, and the quality of the curriculum implementation, and hence to explore ways in which change facilitators can leverage teacher concerns for successful reform.,
Uganda 2022-12-08 12:19:11 2025-12-08 Social Science and Humanities Non-Clinical Trial Degree Award
Simon Nampindo Takozekibi
ID: UNCST-2022-R009914
Population Census of African Lion and Spotted Hyena in Murchison Falls Protected Area, Uganda
REFNo: NS447ES

To estimate the density and abundance of the African lion and spotted hyena in Murchison Falls National Park, Bugungu and Karuma Wildlife Reserves using the Spatially Explicit Capture-Recapture (SECR) framework.
Uganda 2022-12-08 12:16:46 2025-12-08 Natural Sciences Non-Clinical Trial Non-degree Award
Rose  Nabatanzi
ID:
Characterization of the latent reservoir among HIV-infected individuals on long-term antiretroviral therapy
REFNo: HS2454ES

1. To validate the intact proviral DNA assay in measuring the latent HIV reservoir size for HIV subtypes A and D
2. To compare the size of the latent HIV reservoir among HIV-infected optimal and suboptimal immune responders on long-term ART
3. To compare the size of the latent HIV reservoir between subtypes A and D among HIV-infected individuals on long-term ART
4. Determine the levels of T cell immune activation/exhaustion among ART-treated individuals comparing subtypes A and D.

Uganda 2022-12-08 12:15:54 2025-12-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
ACCESS TO HIV, TUBERCULOSIS AND MALARIA SERVICES: A GENDER-BASED ASSESSMENT FOR UGANDA
REFNo: HS2549ES

1. To determine the extent to which Uganda is achieving targets of gender interventions in the National HIV&AIDS Strategic Plan (NSP) 2020/21 to 2024/25 and the Sustainable Development Goals.
2. To determine progress against national gender-related targets, highlight key issues affecting gender and HIV, TB as well as malaria responses and the actions needed.
3. To explore communities’ perspectives on the performance and benefits of gender and HIV, TB and malaria response interventions.
4. To generate recommendations aimed at enhancing social accountability, quality and efficiency of interventions in the gender and HIV, TB and malaria response in Uganda.

Uganda 2022-12-08 11:40:48 2025-12-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Muzaale
ID: UNCST-2022-R009515
Investigating the predictors of acceptability of cervical cancer screening among women living with HIV in Kalungu district.
REFNo: HS2573ES

Goal of the study:
To investigate the predictors of acceptability of cervical cancer screening among women living with HIV in Kalungu district.

Specific objectives:
a) To examine the individual factors influencing acceptability of cervical cancer screening among women living with HIV in Kalungu district.
b) To assess the institutional/health facility factors that influence acceptability of cervical cancer screening among women living with HIV in Kalungu district.
c) To investigate the socio-economic factors influencing cervical cancer screening acceptability among women living with HIV in Kalungu district.

Uganda 2022-12-06 16:31:30 2025-12-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Bjorn Van Campenhout -
ID: UNCST-2020-R014080
Quality and food safety in the Ugandan dairy value chain
REFNo: SS1520ES

To measure the impact of visualizing milk quality attributes to farmers and milk collection centers (MCCs) on the compositional quality of milk (butter fat content and solid non-fat content) at both levels.
Belgium 2022-12-06 16:29:54 2025-12-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
PEACE MUTUUZO REGIS
ID:
Public Policy and Gender Transformation: A Case of affirmative action for Women’s Political Participation in Uganda
REFNo: SS1504ES

Main objective

To examine the effect of affirmative action for women’s political participation on gender transformation in Uganda between 2011-2021.


Specific objectives

1. To assess the existing policies that promote women’s political participation in Uganda.
2. To examine the effect of affirmative action for women’s political participation on gender relations in Parliament and District Local Councils.

3. To examine the effect of affirmative action for women’s political participation on gender relations in the local community.

4. To explore the structural barriers that prevent women in the political space from achieving gender transformation.

5. To identify other strategies that can be employed to achieve gender equality in Uganda other than affirmative action.

Uganda 2022-12-06 16:27:05 2025-12-06 Social Science and Humanities Non-Clinical Trial Degree Award
Santorino Data
ID: UNCST-2019-R001487
MamaOpe Pneumonia Diagnostic device: A feasibility, acceptability and effectiveness evaluation in Uganda
REFNo: HS2533ES

We aim to determine the feasibility and acceptability of a wearable device by frontline health workers in the chest examination Determine the accuracy of the wearable pneumonia diagnostic device in measuring the respiratory rate, determination and interpretation of lung sounds using an algorithm to inform the likely presence or absence of pneumonia. ,
Uganda 2022-12-06 16:21:06 2025-12-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sarah Walker
ID:
The regional dynamics of deforestation. Evidence from Kenya and Uganda
REFNo: SS1485ES

Given the pervasiveness of insecure land tenure institutions around the developing world, and the role of historical institutions in shaping preferences and behavior, it is important to understand how the design of PES programs may interact with historical land tenure structures. In this project, we design a willingness to accept experiment, and framed field experiment, across three regions of Uganda to answer the following questions:

1. What is the optimal design of an avoided deforestation PES program in Uganda?
2. How do land tenure institutions impact the design of an avoided PES program in Uganda?
3. How does the security of land tenure impact deforestation behavior and trust in Uganda?
USA 2022-12-05 12:03:29 2025-12-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paddy Asiimwe Junior
ID:
ADVANCED LOCALIZATION TECHNIQUES ON SMART DEVICES FOR INCLUSIVE LOCATION-BASED SERVICES: A FOCUS ON HEALTHY AGING FOR THE ELDERLY WITH DEMENTIA IN RURAL COMMUNITIES
REFNo: SIR169ES

The main objective is to develop a remote-based comprehensive monitoring and positioning system for people with dementia in rural communities.
Specific objectives
1. To conduct a site survey in Apac district to identify homes and explore the challenges people living with dementia face.
2. To analyze data collected.
3. To design a comprehensive energy efficiency monitoring and positioning system for people with dementia in rural communities.
4. To develop and test the system in Apac District.

Uganda 2022-12-01 10:53:14 2025-12-01 Engineering and Technology Non-Clinical Trial Non-degree Award
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