Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Irene Mbatidde
ID:
ANTIMICROBIAL USE AND RESISTANCE IN POULTRY PRODUCTION CHAINS IN SOROTI AND WAKISO DISTRICT, AND THE ASSOCIATED OCCUPATIONAL HEALTH RISKS
REFNo: A166ES

General Objective Understanding antimicrobial use patterns, their influence on the development of AMR along the poultry value chains and associated health risk factors among value chain workers in Wakiso and Soroti districts Specific Objectives Describe antimicrobial use patterns under intensive and free-range poultry production systems in Wakiso and Soroti respectively • Explain AMR for selected antibiotics at various points along the poultry production chain in Wakiso and Soroti districts • Develop a risk pathway for poultry associated AMR in Wakiso and Soroti • Quantify residues of (sulphurdiazine, tetracycline, neomycin) in poultry meat
Uganda 2022-04-28 2025-04-28 Agricultural Sciences Non-Clinical Trial Degree Award
Simon Peter Kibira Peter Sebina
ID: UNCST-2019-R000492
Covid-19 vaccine hesitancy among school teachers: a qualitative exploration of the driving factors
REFNo: SS1242ES

1.To explore the contextual, vaccine-specific, individual and group-specific drivers of Covid-19 vaccine hesitancy among school teachers in Uganda.
2.To explore facilitators of vaccine uptake for Covid-19 among school teachers in Uganda.
3.To describe the product attributes of the ideal Covid-19 vaccine from the perspective of school teachers.
Uganda 2022-04-27 2025-04-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
Evaluation of the Safety , Efficacy and Stability of Sangatraz®-125 & Sangatraz®-250: A Randomised Single-Blinded Positive Controlled Multi-Site Acaricides Field Trial
REFNo: A186ES

General objectives To determine the efficacy, safety and stability of Sangatraz®-125 & Sangatraz®-250(Sanga Vet. Chem. Ltd, Kampala Industrial Park, Namanve ) when applied onto cattle by hand spraying and plunge dipping for tick control. Specific objectives The specific objectives of this acaricide field trial will to to determine; i.efficacy of Sangatraz®-125 & Sangatraz®-250 when applied onto cattle by hand spraying and plunge dipping for tick control. ii.safety of Sangatraz®-125 & Sangatraz®-250 when applied onto cattle by hand spraying and plunge dipping for tick control. iii.Stability of Sangatraz®-125 & Sangatraz®-250 when applied onto cattle by plunge dipping for tick control.
Uganda 2022-04-25 2025-04-25 Agricultural Sciences Clinical Trial Non-degree Award
Marie Sabacka
ID:
Microbial diversity of disappearing tropical glaciers in Uganda
REFNo: NS348ES

Study microbial diversity of disappearing glaciers in Uganda
Czech Republic 2022-04-25 2025-04-25 Natural Sciences Non-Clinical Trial Non-degree Award
Gladys Ayot Florence
ID:
Exploring Experiences of Domestic Violence for Female Teachers in Secondary Schools in Uganda
REFNo: SS1273ES

4. Explore the support mechanism available to female teachers affected by domestic violence.,3. Provide a description of female teachers’ reports on how staff affected by domestic violence negotiates through the challenges of domestic violence in performing their duties.,2. Assess the female teachers’ perspectives about the impact of domestic violence on the administrative roles of teachers.,1. Assess from the female teachers’ perspective how domestic violence affects teachers’ teaching function/roles.,The purpose of this study is to explore the experiences of female teachers affected by domestic violence, describe how domestic violence affects the professional roles of a teacher of secondary schools and to establish how administrators manage the situation for affected staff in schools in northern Uganda.,
Uganda 2022-04-22 2025-04-22 Social Science and Humanities Non-Clinical Trial Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
LINKAGES BETWEEN SUSTAINABLE DEVELOPMENT GOALS IN UGANDA - A FOCUS ON HEALTH
REFNo: HS2015ES

To understand how stakeholders in Uganda perceive and assess linkages between health and non-health determinants and their impact.,To determine the strength, position, and nature of linkages between health and other SDGs in Uganda using the SDG synergies approach. ,The overall aim of this project is to identify, describe, and classify linkages between SDGs focusing on health at the country level in Uganda.,
Uganda 2022-04-22 2025-04-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
EXPLORING THE PATHWAYS OF LEPROSY FROM COMMUNITIES TO DIAGNOSIS TO FINE-TUNE INTERVENTIONS IN THE DISTRICTS OF MAYUGE, YUMBE AND KASESE, UGANDA
REFNo: SS1182ES

1. To describe the reasons for delay in seeking health care for leprosy patients diagnosed in three districts of Mayuge, Yumbe and Kasese
2. To describe the knowledge, attitude and practice among members of communities and health care providers in reference to leprosy

Uganda 2022-04-22 2025-04-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Kakooza
ID:
Molecular Epidemiology and Antimicrobial Resistance Determinants of Neisseria gonorrhoeae among males with urethritis in Kampala, Uganda
REFNo: HS2191ES

Main Objective
To elucidate the genomic epidemiology and AMR determinants associated with NG strains circulating in Kampala Uganda
Specific Objectives
• To describe the NG AMR Surveillance Programme in Kampala, Uganda and the emerging phenotypic antimicrobial susceptibility data generated using E-test method
• To determine the genomic epidemiology of NG strains circulating in Kampala, Uganda using WGS and compare findings with behavioural, demographic and clinical metadata
• To identify the molecular AMR determinants associated with decreased susceptibility and/or resistance to NG using WGS and correlate with phenotypic AMR data

Uganda 2022-04-22 2025-04-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Shana Warren
ID:
Vitamin A Supplementation (VAS) Post Event Coverage Survey (PECS) in Uganda
REFNo: SS1261ES

To conduct a PEC survey for the October-November 2021 round of the ICHD in Uganda,
USA 2022-04-21 2025-04-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Routine SARS CoV-2 screening using Antigen Rapid diagnostic test to detect and control transmission of infections in markets and trade hubs in Kampala City – A pilot study.
REFNo: HS2197ES

4. To estimate the cost of implementing routine use of SARS CoV-2 Ag RDTs in markets and trade hubs,3. To assess the feasibility of use of Ag-RDTs in contact tracing for early identification of SARS-CoV-2 infections,2. To identify high risk groups that drive SARS-CoV-2 transmission in markets and trade hubs ,1. To pilot the use of routine SARS-CoV-2 Ag-RDT for the early detection of SARS-CoV-2 infections in markets and trading hubs within Kampala to control transmission ,
Uganda 2022-04-21 2025-04-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phillip Ssekamatte
ID:
IMMUNOLOGICAL, METABOLIC AND GENETIC CHANGES AMONG PATIENTS WITH TUBERCULOSIS AND TYPE 2 DIABETES MELLITUS IN UGANDA
REFNo: HS1696ES

Study objectives

General objective
To assess the effect of type 2 DM on Mtb-specific T-cell subset functional phenotypes during metformin and isoniazid therapy, and type 2 DM on the immunological, metabolic and genetic TB responses.

Specific objectives
(i) To determine the effect of type 2 DM on frequency, function (activation and cytokine secretion), and survival of Mtb-specific T-cell subsets (CD4+ and CD8+) in patients having both type 2 DM and LTBI during metformin and isoniazid therapy.
(ii) To assess baseline differences in Mtb-specific T-cell subset functional phenotypes to LTBI between people with and without type 2 DM.
(iii) To profile baseline immune-metabolic changes among type 2 DM and LTBI patients.
(iv) To investigate baseline differences in gene expression signatures (TB Risk-11) to LTBI between people with and without type 2 DM.

Uganda 2022-04-21 2025-04-21 Medical and Health Sciences Non-Clinical Trial Degree Award
Barnabas Bakamutumaho
ID: UNCST-2021-R012636
Maintenance and transmission of Rift Valley Fever Virus and other emerging infectious diseases in East and Central Africa: Version number: 1.0
REFNo: HS1713ES


(i) Determine whether low-level RVF virus transmission and disease among or between animals and humans occurs during the inter-epidemic periods (IEPs)
(a). To describe host immune responses to RVF infections in humans and livestock during inter-epidemic periods.
(ii) Conduct detailed niche modelling of RVF high risk and low risk ecologies to determine the important ecological risk factors associated with persistence of RVF virus and recurrence of outbreaks in animals and humans.
(iii) Investigate impact of climate change on the RVF permissive ecologies and its effect on RVF virus transmission
2.2.2 Secondary objective
(iv) Conduct pathogen discovery on human, livestock, and wildlife samples collected from ECA countries to identify other circulating emerging infectious pathogens which are of epidemic or pandemic potential.

Uganda 2022-04-21 2025-04-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Etheldreda Nakimuli-Mpungu
ID: UNCST-2020-R014808
Tele-Psychotherapy for Youth using Mobile Phones during Covid-19 Pandemic
REFNo: HS2106ES

1. We aim to conduct online and community-based participatory qualitative research to obtain information on the potential usefulness of individual tele-support psychotherapy in addressing depression during the Covid-19 pandemic.
2. We will compare the effectiveness of individual tele-support psychotherapy (TSP) delivered by trained lay counsellors in combination with standard mental health services (SMHS) for depression with use of SMHS alone.
3. We aim to compare the effects of TSP combined with SMHS and SMHS alone on other psychosocial variables including self-esteem, anxiety, alcohol and substance use, social support, stigma, number of disability days, asset possession, poverty indices, and cost-effectiveness measures.
4. To conduct a process evaluation of trial activities informed by Linnan and Steckler’s process evaluation frameworks to specifically determine indicators of feasibility, acceptability, fidelity, and to explore causal mediating processes and contextual influences
5. We will also explore whether or not the effects of TSP and SMHS are moderated by alcohol and drug use.
6. We shall explore whether the strength of a therapeutic relationship will mediate the effects of TSP and SMHS on depression
Uganda 2022-04-21 2025-04-21 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Erume
ID:
Profiling virulence markers and drivers enabling Escherichia coli to cause neo-natal and post-weaning piglet diarrhea in major pig producing districts of Uganda
REFNo: A190ES

1. To determine the adhesins in the 157 E. coli previously isolated from Kayunga and Mityana districts, Central Uganda
2. To determine the significance of E. coli species in the etiology of piglet diarrhea in the major pig producing districts of Uganda.
3. To determine drivers which underlie the dynamics and perpetuation of E. coli infections of pigs in the major pig producing districts of Uganda.
4. To molecularly characterize virulence markers of E. coli species involved in diarrheal outbreaks in piglets in the small holder pig production systems in major pig producing districts of Uganda.
5. To determine the antimicrobial susceptibility of E. coli isolates isolated from diarrheic piglets in the small holder pig production systems in selected major pig producing districts of Uganda.
Uganda 2022-04-21 2025-04-21 Agricultural Sciences Non-Clinical Trial Non-degree Award
Paula Rabaey Ann
ID:
A seat for every child: Ensuring safe and dignified mealtimes for children with disabilities
REFNo: SS1247ES

Determine in country stakeholder interest in promoting and using the chair,Determine percent change in caregiver stress level while feeding child in the chair versus current position (without adaptive equipment),Determine ability and level of ease/difficulty with which caregivers can independently position their child correctly in the chair ,Determine change in feeding position and tolerance for using the chair (from child’s current feeding position to being fed in the chair),To pilot test SPOON Foundation’s low-cost feeding chair for acceptability, usability, and feasibility for families with a child with a disability (CWD) in Uganda. ,
USA 2022-04-20 2025-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ali Ssetaala
ID: UNCST-2021-R011817
CHILI- Analysis of Cervical cancer burden and screening practices in Uganda
REFNo: HS2167ES

1. To understand the current cervical cancer burden, screening, and management practices in Uganda.
2. To obtain relevant stakeholders’ input before starting the development of the cervical cancer screening intervention with a self-sampling device.
Uganda 2022-04-20 2025-04-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
An exploratory, mixed-method study of family planning self-care in Nepal, Niger, and Uganda
REFNo: HS2117ES

1. To explore perceptions of FP self-care among women of reproductive age (15-49 years) and men age 18 years and above. 2. To describe FP self-care behaviors and preferences among women of reproductive age (15-49 years) and men age 18 years and above. 3. To examine provider perspectives on FP self-care
Uganda 2022-04-20 2025-04-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
Effect of maternal exposure to air pollution on birth weight outcomes: A cohort Study among Urban Communities in Wakiso District, Uganda
REFNo: HS2141ES

To describe the association between maternal exposure to air pollution and pregnancy complications of antepartum haemorrhage and pre-eclampsia.,To describe the factors associated with the levels of PM 2.5 personal exposure among pregnant women in Urban Communities in Wakiso District, Uganda,To describe the association between maternal air pollution exposure (PM 2.5 and birth weight of their babies.,To assess the effect of maternal exposure to particulate matter on birth outcomes in Urban Communities in Wakiso District, Uganda,
Uganda 2022-04-20 2025-04-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Janepher Nyakake
ID:
Supporting young and female entrepreneurs for SME growth in Uganda and Somalia
REFNo: SS1256ES

To analyze the “potential impacts” of the interventions of these two innovation agencies on their supported SME clients to develop a package for rigorous evaluation.
Uganda 2022-04-20 2025-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rebecca PAHULJE Rose
ID:
Examining the northward shift in the distribution of African fishes in association with climate change
REFNo: NS345ES

To understand how climate is affecting the physiology and distribution of tropical fishes.

Specifically;
- To quantify the thermal limits and hypoxia tolerance of tropical fishes and the degree to which these limits are plastic
- To understand and predict how tropical fishes will respond to climate change – either via persistence in situ or changing their distribution by moving to more favourable thermal/oxygen regimes.
Canada 2022-04-20 2025-04-20 Natural Sciences Non-Clinical Trial Degree Award
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