Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ALEX NDYABAKIRA
ID:
Assessing use of SolarSack for treatment of safe drinking water in Uganda
REFNo: HS1680ES

1. To determine the willingness to buy and acceptability of SolarSack water treatment device
2. To determine the most appropriate cost per unit for SolarSack for rural, peri-urban and urban settings
3. To explore user preferences for the SolarSack device
4. To determine the effect of SolarSack use on prevalence of waterborne diseases

 Uganda 2021-10-11 2024-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phyllis Kisa
ID: UNCST-2023-R007952
 SURGICAL NEONATES IN A LOW-RESOURCE SETTING: AN AUDIT OF NUTRITION AND OUTCOME
REFNo: HS1736ES

To audit our current the nutritional regime among newborns with gastro-intestinal anomalies admitted to the Paediatric Surgical Unit at Mulago National Referral Hospital(MNRH).
Uganda 2021-10-11 2024-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tukwasiibwe Moses
ID:
Impact of forced displacement on labour markets in Uganda
REFNo: SS1039ES

Objective 1) Provide strong empirical evidence of the direct and indirect impacts. Against the backcloth of a comprehensive literature survey, and investigating non-camp urban refugee populations in Kampala and as well as camp based refugees in Nakivale refugee settlement in Uganda.

Objective 2) Identify the mechanism(s?) through which impacts occur. Analyzing the empirical evidence we will: i) explore direct and indirect (partial equilibrium) impacts and outcomes on the dynamics of labor market and business behavior, assessing impact-attribution and correlating variables such as labor supply and wages, capital investment/ labor trade-offs and demand side factors, productivity and skills, national and international investment patterns; ii) assess the role of political economy, regulatory and policy frameworks; iii) generate qualitative analysis of household and individual livelihood/life course experiences in relation to labor market outcomes, iv) generate local, national and comparative findings.

Objective 3) Support the development of evidence-based, effective, and context-specific jobs policy advice. The analytical outputs will provide a robust evidence base for jobs policy advice envisaged at different levels (local, national, and international), and for different stakeholders (e.g. municipal and national governments, donors, intergovernmental and non-governmental organizations, private sector investors, entrepreneurs and SME sector, and displaced and host populations). Policy advice will include, inter alia: finance and investment strategies, regulatory framework e.g. rights to work/rights at work and employer conditions for decent work), spatial planning, training and skills, role of investment incentives, socio-economic policies for displaced and host populations vis à vis labor markets.

Objective 4) Generate new data that will be in the public domain for use in further research. The proposed study will generate new statistical (survey) data sets for three of the four case countries: Colombia, Ethiopia and Uganda. In Jordan, the study team is already in possession of sufficient data through previous surveys conducted by Fafo and partners. When designing the new surveys, special attention will be given to establish robust baselines that can be applied in future impact analyses. Responding to this objective and the general TOR requirements, we shall place all the data generated in the proposed project in the public domain.

Uganda 2021-10-11 2024-10-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
PETER OMASWA
ID:
Relevance and Factors Affecting Exchange of Plant Material and Data to Conservation
REFNo: NS156ES

General Objective
To assess the importance of plant material and data exchange between African and European Institutions for conservation.

Specific Objectives
1. To review the extent to which plant material and data are exchanged between African and European institutions.

2. To evaluate the opportunities and constraints to plant material and plant data exchange between African and European Botanical Institutions.

3. To evaluate the proportion of exchanged plant material and data translated into conservation applications.


 Uganda 2021-10-08 2024-10-08 Natural Sciences Degree Award
Carolyn Nakisige
ID:
Preventing cervical cancer in HIV-infected Kenyan and Ugandan women
REFNo: HS1372ES

1. To evaluate HR-HPV DNA testing of self-collected vaginal swabs combined with VIA in screening for cervical cancer in HIV-infected women.
2. Determine if aflatoxin is a risk factor for cervical cancer among HIV-infected Kenyan and Ugandan women.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alice  Emasu
ID: UNCST-2021-R013920
 EXPERIENCES OF LIVING WITH OBSTETRIC FISTULA AMIDST COVID -19 PANDEMIC IN EAST AND CENTRAL UGANDA: Qualitative study.
REFNo: HS1464ES

General Objective
To document the experiences of living with fistula amidst the COVID-19 pandemic among women who developed OF during corona virus pandemic, those who had fistula and had started seeking for care, those who were repaired and were at the stage of reintegration and those declared as incurable between 15-49 years of age from Eastern and Central Uganda

Specific objectives

1) To document participant’s awareness about COVID 19 Pandemic

2) To explore the perceptions of women living with OF amidst COVID 19 Pandemic

3) To explore the effect of COVID -19 on the livelihood of women with OF.

4) To explore experience in accessing fistula services among women reintegrating and screened for surgeries during the COVID-19 pandemic.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
 Aging with HIV: Experiences and challenges of older adults 50 years and above living with HIV
REFNo: HS1759ES

3. To explore determine the challenges faced by older adults 50 years and above aging with HIV.,2. To describe the experiences of older adults 50 years and above aging with HIV.,The goal of this study is to explore the experiences, perceptions, and challenges of older adults 50 years and above aging with HIV.,
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Juma Kalyegira
ID:
The Role of Basic Psychological Needs Satisfaction for the Psychological Wellbeing and Social-Cultural integration of Refugees in Rhino Camp Refugee Settlement, Uganda
REFNo: SS905ES

• To estimate the relationship between the three psychological basic needs satisfaction (Autonomy, relatedness and competence) to the psychological wellbeing of refugees.
• To determine whether the basic psychological needs satisfaction influences refugee integration.
• To find out what factors influence the need satisfaction/frustration for refugees and how?
• To estimate whether physical and psychological need satisfaction interact in an “unprepared to benefit” or “buffering against adversity” direction?

Uganda 2021-10-08 2024-10-08 Social Science and Humanities Non-Clinical Trial Degree Award
John Byabagambi Bekiita
ID:
Ability and willingness to pay for voluntary medical male circumcision in Uganda: A mixed-methods study
REFNo: HS1523ES

1. To identify the factors that determine the ability to pay for VMMC in Uganda.
2. To determine the factors associated with willingness to pay for VMMC services in Uganda.
3. To find out the reasons that inform the choice of either the willingness to pay or not to pay for VMMC services in Uganda.

 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Julian Adong
ID: UNCST-2021-R013487
 Pandmic-related disruptions in HIV care among adolescents and young adults with HIV (AYAWHIV) and the potential for mHealth interventions.
REFNo: HS1686ES

To examine the effects of the COVID-19 restrictions on HIV treatment of AYALWHIV and assess the potential of mHealth intervention in bridging these disruptions.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
 Transactional sex and HIV among men in Rakai, Uganda
REFNo: SS984ES

The overall goal of this research is to understand the characteristics of men who engage in transactional sex and the causal pathways that lead from transactional sex to incident HIV in Rakai, Uganda.
• Aim 1. To measure perceptions, content validity, and response processes of transactional sex measures in the Rakai Community Cohort Study
• Aim 2. To examine men’s experiences in transactional sex relationships and factors that may heighten risk for HIV

Uganda 2021-10-08 2024-10-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dorothy Stamps Sarah
ID: UNCST-2019-R001036
 Dry Rifting in the Albertine-Rhino graben, Uganda (DRIAR)
REFNo: NS294ES

Investigating the physics of strain accommodation in the magma-poor Albertine- Rhino Graben of the East African Rift System using geodynamic modeling and GNSS geodesy
 USA 2021-10-08 2024-10-08 Natural Sciences Non-Clinical Trial Non-degree Award
Marsiale Kamugisha
ID:
'Analysing the Impact of Transformative Governance and Agroforestry on Household Food Security in Southwestern Uganda'
REFNo: A130ES

1)To assess contributory factors responsible for determining household transition to food security.
2)To evaluate the household governance system that enhances agroforestry-based food security.
3)To assess households’ potential benefits of agroforestry beyond food security.

Uganda 2021-10-06 2024-10-06 Agricultural Sciences Non-Clinical Trial Degree Award
Nadine Schubert
ID:
Genetically-based social communication in an inbred group-living wild mammal
REFNo: NS273ES

The aim is to investigate the role of immune genes of the major histocompatibility complex (MHC) in affecting odour cues used for social communication in banded mongooses. Furthermore, we want to investigate the link between MHC composition of an individual and fitness parameters as well as the impact of the MHC on microbiota communities. Last, it is crucial to test the ability of banded mongooses to discriminate MHC-based differences in odour cues in a natural setting.
 Germany 2021-10-05 2024-10-05 Natural Sciences Non-Clinical Trial Degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 Clinical Predictors of 3-Months Isoniazid Rifapentine (3HP)- Related Adverse Drug Reactions (ADR) During Tuberculosis Preventive Therapy (PAnDoRA-3HP study)
REFNo: HS1582ES

Primary Objectives
1.To describe the safety profile of 3HP among people receiving tuberculosis preventive therapy.
2.To describe the effect of adverse drug reactions on tuberculosis preventive therapy completion rates
Secondary Objective
1.To describe the pharmacokinetic and pharmacogenomic determinants of ADRs among people receiving tuberculosis preventive therapy in Uganda
2.To determine the efficacy of 3HP when used for tuberculosis preventive therapy.

 Uganda 2021-10-04 2024-10-04 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
 An International Multicenter, Randomized, Double-Blind, PlaceboControlled Trial of the Safety and Efficacy of Anti-Coronavirus Hyperimmune Intravenous Immunoglobulin for the Treatment of Adult Outpatients in Early Stages of COVID-19
REFNo: HS1715ES

Primary Objective
Primary objective: Among outpatients with recently diagnosed SARS-CoV-2 infection to compare the safety and efficacy of a single infusion of hIVIG (pooled for the 2 hIVIG

products) versus placebo, each given with SOC, on clinical status after seven days. Two hypotheses will be tested to address this primary objective, which compares the primary endpoint among two study populations: 1) participants where neutralizing MAb was not specified as part of SOC treatment (stratum 1, see Section 6.1 Overall Study Design); and 2) all randomized participants (stratum 1 and stratum 2 combined). hIVIG will be considered superior to placebo if either of the two hypotheses are rejected.
Secondary Objectives and Endpoints
Secondary objectives, including subgroup analyses and safety outcomes, will be addressed for all randomized participants and for those in stratum 1 and 2 separately.
Secondary Endpoints
The clinical status as classified on the ordinal outcome scale will be assessed with a number of additional analyses comparing hIVIG (pooled for the 2 hIVIG products) with placebo, among the overall study population as well as for the key subgroup of those not receiving anti-SARS-CoV-2 monoclonal antibodies as part of SOC (stratum 1), including:
1. All-cause hospitalization or death through 28 days.
2. All-cause mortality through 28 days.
3. Significant disease progression through 28 days, using a time to event analysis with outcome defined by fulfilling criteria for category 4 or 5 on the ordinal scale.
4. Distribution of ordinal scale outcome at Day 4, 14, and 28.
5. The proportion of participants with any disease progression at Day 7, using a sliding dichotomous scale progression defined by a categorization on the ordinal scale that is worse than the status at entry

 Uganda 2021-10-04 2024-10-04 Medical and Health Sciences Clinical Trial Non-degree Award
Joyce  Nankumbi
ID:
The status of OFSP production, utilization and the nutritional status and welfare of sweet potato growing households in northern and eastern Uganda
REFNo: A152ES

1. To characterise the consumption of vitamin A rich foods among households in the selected northern and eastern districts of Uganda 2. What is the food security status in the households in the selected northern and eastern districts in Uganda? 3. To document the production and consumption of orange-fleshed sweet potato among households in the selected northern and eastern districts in Uganda? 4. To identify infant feeding practices of women in the selected districts of northern and eastern regions in Uganda? 5. To identify water, hygiene and sanitation practices of households in the selected northern and eastern districts in Uganda 6. To establish the knowledge, attitudes and perception on the consumption of beta carotene-rich orange-fleshed sweet potatoes/ vitamin A-rich foods among households in the northern and eastern regions in Uganda,To determine status of orange-fleshed sweet potato production, utilization and the nutritional status and welfare of sweet potato growing households. in northern and eastern Uganda ,
 Uganda 2021-10-01 2024-10-01 Agricultural Sciences Non-Clinical Trial Non-degree Award
Arthur Nuwagaba
ID:
TOP MANAGEMENT TEAM CHARACTERISTICS AND PERFORMANCE OF UGANDAN STATE AGENCIES
REFNo: SS999ES

iv. Establish the joint effect of top management team characteristics, strategy implementation and external environment on the performance of Ugandan state agencies.,iii. Determine the moderating effect of the external environment on the relationship between top management team characteristics and the performance of Ugandan state agencies.,ii. Establish the mediating effect of strategy implementation on the relationship between top management team characteristics and performance of Ugandan state agencies.,i. Determine the influence of top management team characteristics on the performance of Ugandan state agencies.,The main objective of the study is to determine the influence of strategy implementation and external environment on the relationship between the TMT characteristics and the performance of state agencies in Uganda.,
 Uganda 2021-10-01 2024-10-01 Social Science and Humanities Non-Clinical Trial Degree Award
Wang Vibeke
ID:
Supporting Parenting Care Corners in Markets to Reduce Unpaid Care Work for the Vulnerable Business Women in Uganda
REFNo: SS944ES

1. To deepen the evidence base on whether and how reducing women’s unpaid childcare burden increases their productivity and income.
2. To examine the factors that impede access to parenting care facilities among vulnerable women engaged in business markets in Uganda and how these could be mitigated.
3. Evaluate the effects of parenting care facilities, financial subsidy and parents’ training on the productivity of mothers and profitability of their businesses.
4. To inform government action through tested and proven models for scaling up parenting care corners to both structured and unstructured markets
5. To provide proof of concept on how governments can introduce affordable, effective, and sustainable childcare models that work for vulnerable mothers who work in informal markets in Uganda.

Norway 2021-10-01 2024-10-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aida Cuni Sanchez
ID:
Monitoring forest dynamics in Bwindi National Park
REFNo: NS282ES

• Does tree growth change with increasing altitude?
• How do taxonomic, forest structural and environmental attributes affect tree growth?
• How do carbon stocks change over time at different altitudes?

 Spain 2021-10-01 2024-10-01 Natural Sciences Non-Clinical Trial Non-degree Award
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