Sebastian Linnemayr
ID: UNCST-2021-R012696
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R01 Study “INcentives and ReMINDers to Improve Long-term Medication Adherence” (INMIND)
REFNo: SS3732ES
Main Objective
1. We propose to optimize an adaptive intervention using the INMIND approach in a Stage III efficacy randomized trial using a two-stage SMART design in Uganda. All clients (including the control group) will receive information about the importance of behavioral routines, as is part of the standard adherence counseling for treatment initiators and create personalized ART adherence anchoring strategies. We will first enroll patients into an Wisepill use only phase for one month. We will then randomize them to receive either usual care / information only or low-cost daily text messages. All clients will have the opportunity to select a new anchoring plan in the first two months, so that they then have another 4-month period during which to establish a routine. Those who if fail to take their ART pills very regularly, meaning at the same time for at least 80% of the days at the end of month three will be re-randomized to one of two more intensive interventions for the subsequent three months: monthly or monthly escalating prizes.
The Specific Aims are to:
SA1 (Primary): Test the first-stage main effect of Messages vs. Control on the maintenance of ART adherence (primary outcome) and viral suppression (secondary outcome).
SA2 (Secondary): Examine (a) the second-stage main effect of receiving monthly vs. monthly escalating incentives on the primary and secondary outcomes among first-stage non-responders, and (b) whether changing one’s anchoring plan at month two moderates the effect of monthly and monthly escalating incentives.
SA3. Synthesis Phase: Perform a cost-effectiveness analysis including a comparative analysis of the INMIND components among first-stage responders and non-responders and conduct information dissemination activities in Uganda after completion of the trial.
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USA |
2025-04-02 9:23:18 |
2028-04-02 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Henry Kyobe Bosa
ID: UNCST-2021-R013941
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UNDERSTANDING THE SOCIO-ECOLOGICAL AND BEHAVIORAL DRIVERS OF MPOX DISEASE IN AFRICA
REFNo: HS5719ES
General Objective
To assess the state of knowledge, attitudes, and practices, including socio-ecological and behavioral determinants of health considerations, regarding MPXV acquisition and vaccine uptake in Uganda.
Specific Objectives
1. To assess the determinants of the Mpox disease spread and modes of transmission
2. To determine the community’s knowledge, attitude, practices, and perception on Mpox disease
3. To evaluate health-seeking behavior for Mpox disease
4. To identify the barriers and facilitators to Mpox vaccine uptake
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Uganda |
2025-04-02 9:21:50 |
2028-04-02 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Walter Akwat
ID: UNCST-2024-R003452
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Uganda Multi-Sectoral Needs Assessment (MSNA) 2024
REFNo: SS3727ES
• Conduct a thorough inter-sectoral analysis to assess the magnitude and
severity of humanitarian needs and conditions among refugee and host
community households across all 13 formal refugee settlements across
the country and refugee concentrations in Kampala.
• Identify variations in humanitarian needs across different areas of study,
population groups, and household vulnerability profiles.
• Compare key findings of the 2024 MSNA with the Vulnerability and
Essential Needs Assessment (VENA) (2019) and 2018 MSNA.
• Offer insights into inter-sectoral needs to inform prioritization of refugee
response efforts and strategic planning.
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Uganda |
2025-04-02 9:20:09 |
2028-04-02 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Agrace Atwikirize
ID: UNCST-2024-R002716
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Stressors, Coping Strategies, Hope and Academic Perfomance of Teacher-Trainees in Universities in Central Region, Uganda
REFNo: SS3485ES
i. To find out the variations of stressors with biodata among teacher-trainees in universities in Central Region, Uganda.
ii. To investigate the relationship between stressors and coping strategies among teacher-trainees in universities in Central Region, Uganda.
iii. To establish the relationship between coping strategies and academic performance among teacher-trainees in universities in Central Region, Uganda.
iv. To assess if the relationship between stress and academic performance is mediated by coping strategies among teacher-trainees in universities in Central Region, Uganda.
v. To determine the mediating effect of coping strategies and hope on the relationship between stressors and academic performance among teacher-trainees in universities in Central Region, Uganda.
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Uganda |
2025-04-02 9:18:20 |
2028-04-02 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Mohamed Ali Bashir
ID: UNCST-2024-R002641
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PREVALANCE AND FACTORS ASSOCIATED WITH IMMEDIATE ADVERSE PERINATAL OUTCOMES AMONG WOMEN WITH UNINTENDED PREGNANCIES DELIVERING AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5383ES
General Objectives
To determine prevalence and factors associated with immediate adverse perinatal outcome among women with unintended pregnancies delivering at Mbarara Regional Referral Hospital.
Specific Objectives
1. To determine prevalence of immediate adverse perinatal outcomes among women with unintended pregnancies delivering at Mbarara Regional Referral Hospital.
2. To determine factors associated with immediate adverse perinatal outcome among women with unintended pregnancies delivering at Mbarara Regional Referral Hospital.
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Somalia |
2025-04-02 9:16:24 |
2028-04-02 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Cecilia Akatukwasa
ID: UNCST-2024-R002112
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Feasibility and acceptability of the Vxnaid-Immunization Information System (Vxnaid-IIS) for improved Immunization Monitoring and Data Management through Digitization in Wakiso district.
REFNo: SS3734ES
4. To explore stakeholder’s insights and perspectives into future use of Vxnaid-Immunization Information System including sustainability,3. To assess the barriers and enablers to implementation of the Vxnaid-Immunization Information System across four HSDs and four Municipal councils in Wakiso district.,2. To explore key stakeholders’ perceptions, attitudes and acceptance of the Vxnaid-Immunization Information System,1. Explore key stakeholders’ perspectives on practicality, ease of use and overall experience with integrating Vxnaid into current Immunization Information systems across four HSDs and four Municipal councils in Wakiso district.,
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Uganda |
2025-04-02 9:08:21 |
2028-04-02 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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William Blackmon
ID: UNCST-2025-R017006
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Consumer Protection Surveys - Uganda
REFNo: SS3650ES
The project aims to:
• Measure consumer protection risks associated with digital financial services (DFS) usage in Uganda
• Track consumer protection risks across two survey rounds
• Create a comparable cross-country analysis (the survey is also carried out in 10 other countries)
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USA |
2025-04-02 9:06:12 |
2028-04-02 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Maxensia owor
ID: UNCST-2021-R014003
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An open-label randomised controlled trial comparing novel combination and currently used antibiotic regimens for the empiric treatment of neonatal sepsis with a run-in confirmatory pharmacokinetic phase: NeoSep1
REFNo: HS5639ES
In Part 2, a secondary objective is to provide a ranking of clinically relevant antibiotic regimens based on other efficacy and safety secondary outcomes, as well as on health economic measures and the potential selection of resistance. The trial data will provide data to inform the balance between efficacy, safety, costs (and cost-effectiveness and equity, using health economic analysis) and propensity for resistance selection (based on microbiology tests) that will influence facility-level and national decision-making about adoption of studied regimens, and potential future inclusion in WHO guidelines.,In Part 2, the primary objective is to provide a ranking of eight different clinically relevant antibiotic regimens for first-line empiric and second-line (after lack of response/deterioration) treatment in terms of 28-day mortality as the primary outcome measure. It will flexibly compare these multiple different relevant treatment regimens to enable the trial to be run in sites worldwide with very different background rates of different pathogens, of resistance and patterns of routine clinical care by randomising each participant to locally relevant antibiotic regimens agreed prior to site initiation. The trial will ensure generalisability by focusing inclusion based on clinical symptoms associated with high mortality risk in the NeoOBS study, which have been developed into a novel neonatal sepsis severity score – the NeoSep Severity Score.,
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Uganda |
2025-04-02 9:04:16 |
2028-04-02 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Gloria Lubega
ID: UNCST-2025-R017180
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A retrospective review of patients admitted with SARS-COV-2 at Entebbe regional referral hospital in Uganda across multiple waves.
REFNo: HS5695ES
I. To evaluate the mortality rate, risk factors associated with mortality and prolonged hospital admission among patients admitted with severe COVID-19 disease at ERRH.
II. To determine the time to discharge of patients admitted with severe COVID-19 disease at ERRH.
III. To describe the characteristics of patients across different age groups admitted with severe COVID-19 at Entebbe Regional Referral Hospital
IV. To describe treatment options offered to patients admitted with severe COVID-19 disease with reference to Uganda MoH and WHO recommended treatment options.
V. To compare characteristics of patients who were vaccinated against COVID-19 admitted with severe disease and unvaccinated patients admitted with severe COVID-19 disease.
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Uganda |
2025-04-02 9:01:54 |
2028-04-02 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Mark Kaddumukasa
ID: UNCST-2020-R001798
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Building a Collaborative Research and Training Platform for HIV and Rheumatic and Musculoskeletal Diseases in Uganda
REFNo: HS5606ES
Objective 1. Establish the Ugandan Registry of RMDs in HIV (GEMINI), to create a foundation for future prospective studies on HIV and RMDs.
Objective 2. In a pilot study, among a subset of participants from GEMINI with both RA and HIV, compared to participants with HIV only and RA only, explore the impact of co-morbid disease status on markers of bone metabolism, bone mineral density, as well as quality of life and functional disability.
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Uganda |
2025-04-02 9:00:14 |
2028-04-02 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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