Peter Olds
ID: UNCST-2023-R006240
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Evaluation of NT-proBNP in outpatient heart failure care in southwestern Uganda
REFNo: HS5796ES
Main Objective
1. Create and evaluate an algorithm for nurses using a point-of-care biomarker of heart failure (N-terminal-pro hormone B-type natriuretic peptide, NT-proBNP) to support heart failure management in Uganda.
Specific Objectives
1. Identify an average baseline NT-proBNP for patients with HFrEF in the MRRH outpatient cardiology clinic.
2. Develop and compare the use of an algorithm for diuresis based on the NT-proBNP with standard of care diuretic plans for patients with HFrEF in the MRRH outpatient cardiology clinic
3. Evaluate the feasibility and acceptability of implementing an NT-proBNP based algorithm for heart failure care in Uganda
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USA |
2025-04-09 16:31:41 |
2028-04-09 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Jennifer Serwanga
ID: UNCST-2024-R002056
|
VacICoP: Chimpanzee Adenovirus Type 3-Vectored Marburg Glycoprotein (GP)-Expressing Vaccine
(ChAd3-MARV)-Induced Correlates of Protection
REFNo: HS5469ES
This study aims to identify the immune correlates of protection (ICoPs) against Marburg virus disease (MVD) through comprehensive analyses of humoral and cellular responses in both vaccinated and infected individuals. ICoPs will be identified by studying human and non-human
primates (NHPs) that have either survived infection, succumbed to it, or been successfully immunised. The research aims to expedite regulatory approval and licensure by identifying the most effective and durable ICoPs against MVD.
Key objectives and deliverables include:
1. Identifying the MVD ICoPs
2. Detailed humoral and cellular immune profiles distinguishing protective from nonprotective anti-MARV immunity
3. Reference reagents and scalable high-throughput screening assays
4. Predictive statistical models for forecasting vaccination effectiveness
5. Integrated clinical, immunological, and demographic datasets
6. Regulatory guidance for new vaccines approval
7. Global collaborative data exchange framework
|
Uganda |
2025-04-09 16:29:46 |
2028-04-09 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Erisa Mwaka Sabakaki
ID: UNCST-2019-R001625
|
Stakeholder perceptions and ethical considerations in gene therapy clinical trials for sickle cell disease in Uganda
REFNo: SS3570ES
Aim 1: To determine stakeholder perceptions of somatic gene therapy for SCD. We shall engage patient support and advocacy groups to ascertain knowledge gaps, expectations, and preferences regarding gene therapy. This will facilitate patient education and smooth implementation of research and development of affordable and accessible gene therapy in LMICs.
Aim 2: To examine the ethical, legal, and social considerations in somatic gene therapy clinical trials for SCD in a resource-limited setting. We shall use deliberative focus group discussions and key informant interviews to explore the ethical and social considerations in somatic gene therapy research in low-resource settings.
|
Uganda |
2025-04-09 16:28:31 |
2028-04-09 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Willbroad Byamukama
ID: UNCST-2022-R010646
|
RURAL LANDLESSNESS AND FOOD INSECURITY IN UGANDA; A CASE OF KIGEZI SUB-REGION (KABALE, RUBANDA, RUKIGA, AND KISORO DISTRICTS)
REFNo: A561ES
iii. To establish workable strategies to address food insecurity in Kigezi sub-region (Kabale, Rubanda, Rukiga, and Kisoro).,ii. To examine the effect of rural landlessness on food insecurity in Kigezi region (Kabale, Rubanda, Rukiga, and Kisoro).,i. To examine the causes of rural landlessness in Kigezi sub-region (Kabale, Rubanda, Rukiga, and Kisoro).,The purpose of the study is to examine the effect of rural landlessness and food insecurity in, Uganda case of Kigezi region and come up with strategies to increase food security in Kigezi sub region with the rural landlessness.,
|
Uganda |
2025-04-09 16:09:36 |
2028-04-09 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
|
DICKSON NIWASASIRA
ID: UNCST-2024-R003949
|
The Effectiveness of Electronic Media on Utilization of Health Services in a Rural Setting
REFNo: SS3705ES
I. Establish the electronic media channels used by different demographic segments of the rural population to access health information.
II. Determine the impact of electronic media on overall utilization of facility- based Health services in a rural setting.
III. Establish the effectiveness of different electronic media channels on utilization of facility-based health services among different demographic segments of the rural population.
|
Uganda |
2025-04-08 7:35:22 |
2028-04-08 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Glenn Ogolah
ID: UNCST-2025-R017145
|
Asset Financing and Micro Leasing in Agriculture
REFNo: SS3726ES
1. Examining barriers and opportunities in asset financing and micro-leasing
adoption for smallholder farmers and microenterprises:
a. Identifying and analyzing the barriers and opportunities affecting the access of
asset financing solution amongst smallholder farmers
b. Examine gender differences in barriers to accessing asset financing for
smallholder farmers
c. Explore interactions among key stakeholders, including farmers,
microenterprises, SACCOs, and MFIs, to assess their roles and influences in
the asset financing landscape
2. Examining the role of clean energy assets in meeting farmers most urgent needs:
a. Identifying and analyzing the barriers and opportunities affecting the adoption
of clean energy assets by farmers
b. Exploring available productive assets in the market and their distribution
channels for rural farmers
|
Kenya |
2025-04-07 7:58:51 |
2028-04-07 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
.JPG)
|
Josephine BIRUNGI
ID: UNCST-2024-R003480
|
A Roadmap towards the successful deployment of a fixed dose combination of Artemether-Lumefantrine+Amodiaquine (FDC ALAQ) in Uganda (DeTACT Study)
REFNo: SS3706ES
Main Objective: to identify and address obstacles in implementation and deployment of FDC ALAQ at an early stage, and contribute to the smooth introduction of FDC ALAQ in Uganda.
Specific Objectives:
To identify and engage with key national stakeholders involved in Malaria control and introducing new antimalarials in Uganda;
ii. To obtain understanding into relevant policy, regulatory and implementation procedures of new antimalarials and to identify areas that require strategic attention before any new antimalarials are introduced in Uganda;
iii. To develop a practical roadmap that can be used for the effective introduction and deployment of FDC ALAQ in Uganda aiming to control and contain artemisinin resistance in Uganda.
|
Uganda |
2025-04-03 16:55:55 |
2028-04-03 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Robinson Amanyiraho
ID: UNCST-2024-R016357
|
Impact of the Growing Expertise in E-health Knowledge and Skills (GEEKS) Program in Reducing Immunization Defaulters and Enhancing Timely Reporting of Vaccine-Preventable Disease Cases in Uganda
REFNo: HS5737ES
Goal:
The goal of this study is to evaluate the contributions and sustainability of GEEKS Cohort 1 projects, while also providing actionable recommendations to enhance the effectiveness of current and future implementations of the GEEKS program.
Specific Objectives
1.
To document and analyze the contributions of GEEKS Cohort 1 projects in strengthening Vaccine Preventable Disease Surveillance (VPDS) and routine immunization coverage.
2.
To assess the sustainability of GEEKS Cohort 1 projects and identify factors influencing their long-term impact.
3.
To provide evidence-based recommendations for strengthening the design and implementation of current and future GEEKS program initiatives.
|
Uganda |
2025-04-02 9:37:17 |
2028-04-02 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Geofrey Musinguzi
ID: UNCST-2024-R015961
|
HIV Prevention Program Outcomes: Measurement of accessibility, and utilization of key HIV prevention services and linkage to care among adolescent girls and young women, female sex workers, and people who inject drugs in Uganda – A Rapid Coverage Survey
REFNo: HS5730ES
Main objective
The survey’s main objective is to measure the HIV prevention program outcomes among key and priority populations, particularly the AGYW, FSWs, and PWIDs, to inform ongoing and future HIV prevention programs (among such populations) in Uganda.
Specific objectives
1. To assess access to key HIV prevention services and products among AGYW, FSWs, and PWIDs in Uganda.
2. To assess the utilization of key HIV prevention products and services among AGYW, FSWs, and PWIDs in Uganda.
3. To measure the proportion of HIV-positive AGYW, FSWs, and PWIDs linked to HIV/AIDS, STD care and desired health services.
|
Uganda |
2025-04-02 9:35:25 |
2028-04-02 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Stella Achen
ID: UNCST-2025-R016855
|
PARTICIPATORY INTERVENTION RESEARCH TO ADDRESS CHILD EXPLOITATION IN KARAMOJA, UGANDA
REFNo: SS3733ES
i. Explore the main forms of exploitation and modern slavery in Napak and Moroto Districts;
ii. Assess interventions and program components that should be prioritized concerning child exploitation, bearing in mind the major intersecting issues such as gender discrimination, food security, and climate change;
iii. Explore the traditions, narratives, and cultural beliefs that could be mobilized as assets to the program; and lastly,
iv. Map out the key actors and influencers in the child exploitation debate.
|
Uganda |
2025-04-02 9:26:44 |
2028-04-02 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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