Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
FREDDIE SSENGOOBA Peter
ID: UNCST-2021-R011834
 Estimating the cost of introduction, delivery and budget impact of malaria vaccine introduction in Uganda (A prospective projection)
REFNo: HS4096ES

4. To determine the budget impact of introducing and delivering Malaria vaccine among children under five years in Uganda. ,3. To estimate and compare the cost of delivering the malaria vaccine under different vaccination modalities/approaches,2. To estimate the additional resource requirements for the introduction and rollout of the malaria vaccine into Uganda’s routine immunizations programme.,1. To explore perspectives of key stakeholders on Uganda’s plan to introduce the malaria vaccine among children under five years.,To estimate the incremental resources (cost) and budget impact of introducing the new malaria vaccine in Uganda to inform the country decision-making regarding the introduction, delivery, national scale-up, as well as impact of the malaria vaccine on other vaccines in the routine immunization system.,
 Uganda 2024-08-26 18:14:03 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kisembo Vincent
ID: UNCST-2024-R003679
 NATURAL RESOURCE GOVERNANCE AND HUMAN-ECOLOGICAL WELLBEING IN THE OIL AND GAS SUB SECTOR IN BUNYORO SUB-REGION
REFNo: SS2971ES

the study's main objective is to assess natural resource governance and human-ecological wellbeing in the oil and gas sub sector in Bunyoro sub-region, specifically in the districts of Hoima, Kikuube and Buliisa.
Specifically, the study aims to;
1. To analyse the established legal and institutional framework for oil natural resource governance in ensuring the well-being of human -ecological wellbeing in Buliisa, Hoima and Kikuube districts
2. To examine the policies on human wellbeing to the communities in the Oil and Gas sub sector in Buliisa, Hoima and Kikuube districts
3. To analyze the implications of oil and gas sub sector activities on ecological wellbeing in Buliisa, Hoima and Kikuube districts.
4. To examine social and environmental challenges emanating from Oil and gas activities in Buliisa, Hoima and Kikuube districts

Uganda 2024-08-26 15:11:29 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Teopista Akoyi Kevin
ID: UNCST-2024-R004534
 AfriFoodLinks Project - Mbale City Research
REFNo: SS2990ES

d. Actively engage government actors, creating a project feedback mechanism. ,c. Engage other project work packages towards constructing positions on multi-level governance, agri-food system entrepreneurship and innovation and urban food environments,b. Actively contribute to development of urban food system researcher network in partner African cities,a. Support the generation of new and path-leading urban food systems knowledge,to generate scientific evidence to inform actions geared towards transforming urban food systems in such a manner that tackles the systemic foundations of food insecurity and environmental impact.,
 Uganda 2024-08-26 15:00:52 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Herbert Ainamani Elvis
ID: UNCST-2020-R014674
 The Impact of Self Help Plus and Climate Smart Agriculture on Mental Health and Food Security in the Rhino and Nakivale Refugee Settlements of Uganda
REFNo: HS4691ES

To compare the uptake of HGI between the mothers in the combined intervention group (HGI & SH+) with those in the HGI group living in Nakivale refugee settlement,To assess the effect of SH+ on the development of children aged 3-6 years belonging to participating mothers living in Rhino and Nakivale refugee settlements,To assess the effect of SH+ on the mental health of mothers with children aged 3-6 years living in Rhino and Nakivale refugee settlements ,To assess the perceptions and attitudes towards a home gardening intervention (HGI) among participating mothers living in Nakivale refugee settlement,To assess the effectiveness of Self Help Plus (SH+) and home gardening on maternal mental health, food security and child development in the Rhino and Nakivale refugee settlements of Uganda,
 Uganda 2024-08-26 14:58:27 2027-08-26 Medical and Health Sciences Clinical Trial Non-degree Award
Richard Mayanja Weazher
ID:
cultural practice and consumption of indigenous iron artifacts of the Baganda people in Uganda
REFNo: SS2942ES

3. To analyze the extent to which indigenous knowledge of ironworks of the Baganda in Central and Southern Uganda has survived.,2. To examine the historical and contemporary relevance of Indigenous iron implements to the Baganda in Central and Southern Uganda.,1. To document the indigenous knowledge embedded in the design production of the indigenous ironworks of the Baganda in Central and Southern Uganda.,The purpose of this study is to document the cultural practice and consumption of the indigenous iron art forms of the Baganda in central and southern Uganda for posterity. ,
 Uganda 2024-08-26 14:55:51 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Claire Norcross Valerie
ID: UNCST-2024-R004641
 An observational study evaluating archived and emergent HIV drug resistance in people with a history of sub-optimal HIV control in East and Southern Africa
REFNo: HS4761ES

1. To describe archived resistance mutation patterns (major/minor mutations and minority variants) in adults in East and Southern Africa with a recent history of sub-optimal adherence to dolutegravir-based ART; through next-generation sequencing of pro-viral DNA 2. To describe emergent resistance patterns (major/minor mutations and minority variants) in people living with HIV (PLWH) who fail treatment with long-acting injectable cabotegravir/rilpivirine (LAI-CAB/RPV) and the implications for future treatment, and in those who experience blips on LAI-CAB/RPV, through next-generation sequencing on stored plasma 3. To identify predictors of treatment failure on LAI-CAB/RPV in PLWH in East and Southern Africa, and consider how these predictors can influence policy
UK 2024-08-26 14:52:18 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
David Okimait
ID: UNCST-2019-R000095
 We Can Work Baseline for Youth With Disability
REFNo: SS3023ES

To provide relevant recommendations and insights that will further inform the program design and adaptation during the implementation period.,To measure all goal, outcome, and output level indicators as a benchmark for purposes of setting performance targets and measurement of the program progress,The overall purpose of this baseline survey is to establish a benchmark of the program indicators across all five outcomes to inform implementation. This will enable systematic measurement of progress towards the intended results annually and at final evaluation,
 Uganda 2024-08-26 14:45:41 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
FREDRICK MAKUMBI
ID:
Rapid Assessment of Bottlenecks Inhibiting the Scale-up of Evidence-based Family Planning Practices in Uganda
REFNo: HS4723ES

Broad objective To understand enablers and inhibitors to the scale-up of three EBPs (PPFP, task sharing/expansion, and SBCC) and FP broadly through a BNA approach to inform strategies that can accelerate the uptake of family planning services and programme implementation in Uganda. Specific objectives 1.To synthesize what is known about scaling up FP EBPs and broader FP in Uganda, including implementation status, alignment of guidance with national and international standards, and the lessons learned from successful implementation (including approaches that aim to address gender norms and inequalities) 2.To understand the perspectives of key stakeholders (policymakers, programme managers, healthcare managers, service providers and civil society) on the various health systems factors inhibiting the scale-up of the EBPs. 3.Build consensus among key stakeholders on the most important bottlenecks to EBP scale-up and on solutions that address the root causes inhibiting scale-up
Uganda 2024-08-26 14:41:30 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
 What works to prevent and respond to childhood sexual violence in resource-constrained settings: The Case of the 3RT Model implemented by The Remnant Generation in Uganda
REFNo: SS3005ES

4. To study the contribution of girls’ agency in promoting social norms change to prevent childhood sexual violence.,3. To identify critical enablers for effective implementation of interventions to prevent and respond to childhood sexual violence.,2. To explore the role of communities in leading sustainable change for safe environments free from childhood sexual violence. ,To document the effectiveness of the 3RT model in preventing and responding to childhood sexual violence among adolescents in Uganda.,To scientifically examine what works in preventing and responding to childhood sexual violence in resource-constrained settings using the 3RT model of the Remnant Generation as a case. ,
 Uganda 2024-08-26 14:40:04 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Warren Aryeija
ID:
Experiences of People with Infertility in Uganda: Empirical Study of Couples with Infertility Challenges at Selected Hospitals in Kampala City
REFNo: SS2807ES

1. Assess knowledge about the causes of infertility among infertile male and female couples. 2. Identify socio-economic challenges experienced by infertile male and female couples. 3. Examine the psycho-emotional impact of infertility on infertile male and female couples. 4. Explore Coping strategies used by infertile male and female couples in living and dealing with infertility. 5. Determine the Socio-demographic correlates of Coping Strategies adopted by infertile male and female couples.
 Uganda 2024-08-26 14:21:31 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Monicah Agaba
ID: UNCST-2024-R004221
 The Health-Beauty Paradox among Women in Mbarara City Uganda
REFNo: HS4708ES

iii. To characterise the cardio-metabolic profile of WRA.,ii. To document the risk behaviours and their factors related to these societal beauty perceptions.,i. To document societal beauty perceptions and their determinants.,To understand what, why and how the health-beauty paradox is so deeply entrenched in the culture.,
 Uganda 2024-08-26 10:18:37 2027-08-26 Medical and Health Sciences Clinical Trial Degree Award
George William Ddaaki
ID: UNCST-2022-R009216
 Exploring perceptions, concerns, and perceived benefits of pregnant women and those intending to become pregnant towards participating in HIV cure research.
REFNo: SS2866ES

a) To identify concerns and perceived benefits among women in south central Uganda regarding their participation in HIV cure studies.
b) To explore the perceptions and attitudes of pregnant women and those intending to become pregnant in south central Uganda towards participating in a study focused on impact of pregnancy on the HIV viral reservoir and HIV cure.

 Uganda 2024-08-26 10:14:01 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Implementing comprehensive malaria surveillance at sentinel sites in Uganda
REFNo: HS4692ES

To monitor geographic and temporal trends in malaria burden and assess the impact of population level control interventions across a range of epidemiological settings in Uganda.
 Uganda 2024-08-26 10:12:47 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRANCIS KIBIRIGE
ID:
GENDER REFORMS AND POLITICAL SYSTEMS IN UGANDA
REFNo: SS2985ES

The broad objective is to put in context the emerging gender programming reforms in Uganda, particularly the persistent narrative that despite the success in policies that promote women in governance, leadership and employment roles, women voices continue to lag behind.

As a secondary objective, the survey also seeks to increase our understanding of how physical and psychological violence targeting political candidates impacts adult Ugandans’ willingness to engage in electoral politics.


Uganda 2024-08-22 16:38:35 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Irene Mutuzo Esther
ID:
Usability Context and Adoption of Human Capital Management Systems in Ugandan Public Universities: Application of the Unified Theory of Acceptance and Use of Technology
REFNo: SS2972ES

Purpose
This study aims to investigate the influence of usability context on the adoption of HCMS in Ugandan Public Universities by using variables from Venkatesh et al.’s (2003) UTAUT theory.

Objectives
The study will focus on the following objectives:
1. To investigate the influence of performance expectancy on Ugandan public university staff behaviour intention to adopt HCMS.
2. To assess the influence of effort expectancy on Ugandan public university staff behaviour intention to adopt HCMS.
3. To investigate the influence of social influence on Ugandan public university staff behaviour intention to adopt HCMS.
4. To examine the influence of facilitating conditions on Ugandan public university staff’s actual use of HCMS.
5. To investigate the influence of Ugandan public university staff behaviour intention on their actual use of HCMS.
6. To investigate the moderating effect of user background characteristics (gender, voluntariness of use, age, and experience) on the relationship between usability context constructs and the adoption of HCMS among Ugandan public university staff.

Research Questions
The study will focus on the following research questions:
1. What are the obstacles impeding the adoption of HCMS in Ugandan public universities, and how can they be addressed?
2. What are the enabling factors facilitating the adoption of HCMS in Ugandan public universities, and how can they be enhanced?

 Uganda 2024-08-22 16:35:54 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Jose Rubio Valverde Ricardo
ID: UNCST-2024-R003911
 Evaluation of the Pathways out of Poverty (POP) project in the Kitagwenda and Rakai districts of Uganda
REFNo: SS3052ES


1. Assessing the achievement of objectives: The evaluation aims to assess whether POP\'s objectives are achieved, including increasing household income to $2.25/day, reducing the average household Poverty Probability Index score to 22 or less, and ensuring that 60% of households feel their quality of life has improved within 24 months of each cohort\'s initiation.

2. Estimating causal impact: On priority outcomes for HWG - including grow and net household income, household asset endowment, coffee revenue and profits, best practice adoption and yield – the goal is to determine whether it is possible to establish causal inference on the effects of the program on these variables.

3. Conducting heterogeneous treatment effects analysis: The evaluation will analyze variances in the estimated treatment effect across different demographic groups, with a focus on geographic, economic, social and gender factors.

4. Understanding pathways of change: Core to HWG’s agenda is identifying which project components are vital for driving primary outcomes. The evaluation will aim to dissect the project’s multifaceted initiatives to delineate the most impactful pathways tied to changes in income and agricultural productivity.

5. Determining the importance of coffee: With HWG placing a strong emphasis on the role of coffee in household income, the evaluation will focus on measuring how coffee-centered interventions contribute to the broader project outcomes, tying coffee profit and revenue analyses to holistic changes in income.

6. Identifying unintended consequences: The evaluation should also scrutinize potential negative impacts on the environment, health, human rights, community dynamics, and gender equity, such as the effects of agrochemical use, deforestation, community conflicts, labor issues, and changes in household dynamics and resource control.

7. Suggesting operational improvements: Finally, the evaluation should provide actionable insights and recommendations during the implementation period, to increase the efficacy of POP.

 Netherlands 2024-08-22 16:33:12 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSEPH  MURANGIRA
ID:
STRATEGIC MANAGEMENT PRACTICES AND LEGAL CERTAINTY IN UGANDA JUDICIARY
REFNo: SS2917ES

i. To evaluate the effect of strategy formulation on legal certainty in Uganda Judiciary.
ii. To assess the effect of strategy implementation on legal certainty in Uganda Judiciary.
iii. To assess the effect of strategy evaluation on legal certainty in Uganda Judiciary.
iv. To investigate the effect of strategic control on legal certainty in Uganda Judiciary.


 Uganda 2024-08-22 16:30:00 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 HBsAg Rapid Test Device (Whole Blood/Serum/Plasma) (AssureTech) - diagnostic specificity, specimen equivalence and qualification of usability. "CPSP nr ASH-CPH 23-045"
REFNo: HS4685ES

The objective of this evaluation is to establish the performance of the HBsAg Rapid Test Device (Whole Blood/Serum/Plasma) in accordance with the COMMISSION IMPLEMENTING REGULATION (EU) 2022/1107 of 4 July 2022 laying down common specifications for certain class D in vitro diagnostic medical devices in accordance with Regulation (EU) 2017/746 of the European Parliament and of the Council and, the Technical Specifications Series (TSS) for submission to WHO Prequalification – Diagnostic Assessment: TSS-13.,
 Uganda 2024-08-22 16:24:28 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Anti-HCV Rapid Test Device (Whole Blood/Serum/Plasma) (AssureTech) - diagnostic specificity, specimen equivalence and qualification of usability.
REFNo: HS4703ES

The objective of this evaluation is to establish the performance of the HCV Rapid Test Device (Whole Blood/Serum/Plasma) in accordance with the COMMISSION IMPLEMENTING REGULATION (EU) 2022/1107 of 4 July 2022 laying down common specifications for certain class D in vitro diagnostic medical devices in accordance with Regulation (EU) 2017/746 of the European Parliament and of the Council and, the Technical Specifications Series for submission to WHO Prequalification – Diagnostic Assessment: TSS-16 (2021 update).,
 Uganda 2024-08-22 16:20:33 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Linda Grace  Alanyo
ID:
The Role of Social Capital in Enhancing the Reproductive Autonomy of Adolescent Girls in Uganda
REFNo: SS2627ES

To explore the perspectives of immediate caretakers and other stake holders on barriers and facilitators to Reproductive autonomy of adolescent girls,To Assess the Reproductive autonomy of Adolescent girls in Uganda and associated socio-ecological factors ,To synthesize evidence on factors associated with the reproductive autonomy of adolescent girls.,To understand the role of social capital in enhancing the Reproductive Autonomy of Adolescent girls in Uganda,
 Uganda 2024-08-22 16:15:47 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Viola  Nyakato Nilah
ID: UNCST-2021-R013698
 Promotion of a Safe Workplace Environment, Free from Gender-based Discrimination and Violence: A Policy Review and Action Research on the Prevalence of Workplace Gender Discrimination and Violence within the Agriculture, Tourism and Hospitality Sectors in the Rwenzori and Albertine Regions in Uganda
REFNo: SS2600ES

Develop action plans (1 per sector) based on research findings to address gender-based discrimination and violence, and create safe and inclusive work environments.,Identify support structures and mechanisms for work related Gender based discrimination and violence victims available in the region. ,Analyse existing policies and their gaps to address gender-based discrimination and violence at the workplace targeting selected sectors in Albertine and Rwenzori regions. ,To conduct action-oriented research on gender-based discrimination and gender-based violence (GBV) at the workplace targeting agriculture, tourism, and hospitality sectors in the Albertine and Rwenzori regions.,To contribute to the promotion of a Safe Workplace Environment, free from gender-based discrimination and gender-based violence.,
 Uganda 2024-08-22 15:26:06 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kelsey Shaw
ID:
In-situ assessment and collection of fecal sludge from non-sewered sanitation containments: Linking demographic, environmental and technical parameters to microbial activity
REFNo: SIR275ES

The overall objective of this PhD project is to better understand and characterize anaerobic degradation pathways in containment of non-sewered sanitation systems (NSS) in resource constrained settings representative of both urban and rural areas. In view of this, the specific objective linked to this research pertaining to this ethics application is to understand the influence of demographic, environmental and technical (DET) data on measurable fecal sludge parameters as well as microbial community composition within NSS containment across variable geographic regions. The proposed project aims to answer the following specific research questions: - What are the effects and variations associated with physical location, use, and operating conditions on wastewater quality and microbial composition? - What is the relationship between location of sanitation system and behaviors associated with operational parameters? - Is there a link between main concentration gradients in containment and spatially analyzable factors (i.e., demographic, environmental and technical)?
Canada 2024-08-22 15:18:53 2027-08-22 Engineering and Technology Non-Clinical Trial Degree Award
Luke Nyakarahuka
ID: UNCST-2023-R008138
 Surveillance and Research of Viral Hemorrhagic Fever Outbreaks in Uganda: Acute Case Investigation and Survivor Follow-up for Strategic Public Health Intervention
REFNo: HS2964ES

The primary objective is to enhance Uganda’s capacity to rapidly detect, diagnose, respond to, and prevent VHFs including those caused by Ebola, Marburg, CCHF, RVF, Sosuga, and other emerging viruses. To do this, it is critical to understand the incidence, distribution, risk factors for emergence and transmission, immunogenicity and clinical progression (including potential asymptomatic infection), and potential for transmission following clinical recovery of these diseases throughout Uganda, which will enable improved VHF case outcomes, identification of unknown chains of transmission, survivor monitoring, and strategic targeting of public health and animal health resources to prevent and control transmission of these high-consequence viruses.
 Uganda 2024-08-22 15:14:36 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rebecca Nuwematsiko
ID: UNCST-2022-R010501
 Effect and implementation factors of a contextually adapted short message service or phone call intervention to reduce loss to follow-up among presumptive TB patients in North Central Uganda
REFNo: HS3000ES

1.To determine the proportion of pre-diagnosis LTFU among presumptive TB patients and influencing factors in North Central Uganda (Sub-study 1). 2.To explore stakeholder’s perceptions on use of an SMS or phone call intervention to reduce LTFU among presumptive TB patients in health care facilities in North Central Uganda and contextually adapt the interventions (Sub-study 2). 3.To assess the effect of a contextually adapted SMS or phone call intervention to reduce LTFU among presumptive TB patients in health care facilities in North Central Uganda (Sub-study 3). 4.To explore factors that influence implementation of a locally adapted SMS or phone call intervention to reduce LTFU among presumptive TB patients in North Central Uganda (Sub-study 3). 5.To synthesize evidence on effectiveness of mHealth interventions to reduce LTFU in the TB presumption phase in LMICs (Sub-study 4)
Uganda 2024-08-22 13:00:28 2027-08-22 Medical and Health Sciences Clinical Trial Degree Award
AHUMUZA VIANNEY JOHNMARY
ID:
The Refugee Question In Ugandan History 1942-2010
REFNo: SS2297ES

iii. To study the evolution of the relationship between refugees and their host communities,ii. To analyse the changing push and pull factors that shaped refugee flows into and exiting post-Colony Uganda up to 2010.,i. To examine the refugee problem in colonial Uganda.,
 Uganda 2024-08-22 12:54:21 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Mark Okwir
ID: UNCST-2021-R013417
 PREVENTION OF MOTHER-TO-CHILD TRANSMISSION OF HEPATITIS B VIRUS BY ESTABLISHING AN ANTENATAL SCREENING AND VIRAL LOAD TESTING UNIT AND TENOFOVIR DISOPROXIL FUMARATE TREATMENT IN LIRA, NORTHERN UGANDA
REFNo: HS3861ES

To assess the viral load and effectiveness of the TDF therapy.,To assess and enhance knowledge and perceptions of hepatitis B, with the aim of reducing stigma and improving awareness among pregnant women. ,To optimise linkage to care and engagement in the recommended care after receiving a positive HBsAg test during the antenatal period.,To determine the prevalence and risk factors associated with hepatitis B virus infection among pregnant women attending the antenatal clinic in Lira University Hospital and Lira Regional Referral Hospital. ,To assess the implementation of the HBV DNA viral load threshold of ≥10,000 IU/mL for initiating TDF treatment in pregnant women during gestation week 24 or beyond in order to prevent HBV mother-to-child transmission in Lira, Northern Uganda.,
 Uganda 2024-08-22 12:33:06 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Mutekanga
ID: UNCST-2020-R014725
 GEC II Uganda Project
REFNo: SS3024ES

What were the implementation factors behind the GEC-T projects\' success or lack of success? ,To what extent and how did external contextual factors for different projects across the GEC-T portfolio influence their performance?,What were the unexpected or unintended results across the GEC-T portfolio?,What intermediate outcomes did the GEC-T portfolio deliver?,What results did the GEC-T portfolio deliver between the baseline and end line?,The primary objective of the Effectiveness Evaluation will be to assess the effectiveness of the GEC II projects that were designed and implemented through the GEC-T Window. ,
 Uganda 2024-08-22 12:28:28 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Kisitu Paul
ID: UNCST-2024-R004102
 Universal2: Pharmacokinetics, safety and acceptability of a solid paediatric fixed-dose combination of darunavir/ritonavir (DRV/r) 120/20mg for children living with HIV
REFNo: HS4762ES

To evaluate the pharmacokinetics and safety of DRV/r 120/20 mg tablets in children greater than or equal to 3 years of age and weighing 10 to less than 25 kg

To evaluate the pharmacokinetics and safety of DRV/r 120/20 mg tablets in children greater than or equal to 3 years of age and weighing 10 to Less than 25 kg

To evaluate the acceptability of DRV/r tablets in children greater than or equal to 3 years of age and weighing 10 to less than 25 kg

To evaluate the short-term efficacy of the DRV/r 120/20 mg tablets in children greater than or equal to 3 years of age and weighing 10 to less than 25 kg

To describe RTV PK parameters as well as darunavir unbound plasma concentrations.

 Uganda 2024-08-22 11:45:22 2027-08-22 Medical and Health Sciences Clinical Trial Non-degree Award
Ioana Lungu
ID: UNCST-2024-R004378
 Study protocol for baseline data collection on sexual and reproductive health outcomes in Wakiso district
REFNo: SS3049ES

At baseline and prior to the intervention, assess the uptake of HIV testing, ART and PrEP for AYP in our sample in study locations.,At baseline and prior to the intervention, assess the knowledge, perceived norms and attitudes towards contraception and HIV services (testing, ART and PrEP) for AYP in our sample in study locations.,At baseline and prior to the intervention, assess the modern Contraceptive Prevalence Rate (mCPR) for young women and girls in our samplein study locations.,At baseline and prior to the intervention, assess the level of access to high quality, youth friendly health services for AYP in our sample in study locations.,At baseline and prior to the intervention, assess the share of unintended pregnancies for our sample.,
 Romania 2024-08-22 11:39:54 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Agaba Katureebe Ishmael
ID: UNCST-2024-R004089
 Getting a GRIP on Hypertension in Uganda: Giving Repetitive Isometric Exercise for Blood Pressure Control (GRIP in Uganda)
REFNo: HS4712ES

To assess knowledge, attitudes, and practices (KAP) about HTN and experience with IHT (if applicable) ,To measure HTN medication adherence for those prescribed HTN medication during their follow-up, which will be measured through pill counting (counting the remaining amount of pills for prescribed medication).,To assess the need for HTN medication at endline, as per clinical and MOH guidelines, which will be measured through changes in BP levels at week 12,To evaluate the effects of Isometric Hand Training (IHT) on resting diastolic Blood Pressure when compared to standard care after 12 weeks ,To evaluate the effects of Isometric Hand Training (IHT) on resting Systolic Blood Pressure when compared to standard care after 12 weeks ,To determine the efficacy of Isometric Hand Training (IHT) in a population of Hypertension (HTN) patients compared to standard care after 12 weeks of care,
 Uganda 2024-08-22 11:38:26 2027-08-22 Medical and Health Sciences Clinical Trial Non-degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
 ASSESSING THE CONTEMPORARY ECHOCARDIOGRAPHIC DIAGNOSIS AND SECONDARY PROPHYLAXIS OF EARLY-STAGE RHEUMATIC HEART DISEASE
REFNo: HS4694ES

a) To determine the diagnostic accuracy of the 2023 World Heart Federation (WHF) echocardiographic screening criteria for RHD, estimate the cost of RHD screening using the WHF 2023 active case finding algorithm, and a cost analysis of two RHD screening models in Uganda; b) To compare patient-reported outcomes (i.e, treatment adherence, treatment satisfaction and health-related quality of life) among children receiving intramuscular and oral forms of penicillin prophylaxis; and c) To evaluate the cost effectiveness of oral versus intramuscular penicillin for treating early-stage RHD.
Uganda 2024-08-22 11:35:35 2027-08-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Wilson Mathembele
ID:
School Inspection and the Quality of Education in Secondary Schools in Uganda: A case Study of Kasese District
REFNo: SS2957ES

To assess the influence of school inspection on the quality of education in secondary schools in Kasese District,To evaluate the quality of education in secondary schools in Kasese District ,To examine the quality of inspection in the secondary schools in Kasese District,The purpose of this study is to determine the effectiveness of school inspection in ensuring the quality of education in secondary schools in Kasese District in order to improve educational standards and quality outcomes.,
 Uganda 2024-08-22 11:30:39 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Assessment of Longitudinal Lung Function and Sleep Disordered Breathing in COPD Patients in Uganda
REFNo: HS4817ES

1.Assess longitudinal lung function and respiratory symptoms among adults with COPD in Uganda.

2.Determine whether baseline radiographic imaging and inflammatory markers can predict exacerbations at one year among those with COPD.

3.Assess nocturnal sleep patterns and the association between sleep disordered breathing and quality of life.


Uganda 2024-08-22 11:27:08 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Proscovia Nabunya
ID: UNCST-2019-R000970
 Testing the Feasibility and Acceptability of a Combination Intervention to Address Mental Health among Refugee Youth in Uganda
REFNo: SS2834ES

This proposed two-year study will be conducted in two phases. The first phase seeks to understand whether the COVID-19 pandemic had differential impact on refugee youth living in different settings. The second phase will test the feasibility and acceptability of an innovative combination intervention that has not been previously tested among refugee youth to address psychological problems that have increased since the onset of the COVID-19 pandemic. Aim 1. To examine the mental health impact of COVID-19 on refugee youth living in Bidibidi refugee settlement compared to refugee youth living in urban centers (Arua town) in northern Uganda. Aim 2. To test the feasibility, acceptability and preliminary short-term impact of an innovative intervention combining the youth readiness intervention (YRI) with youth development accounts and financial literacy training (YDA-FLT) to address the mental health impact of COVID-19 among refugee youth living in Bidibidi refugee settlement in northern Uganda.
Uganda 2024-08-19 11:03:04 2027-08-19 Social Science and Humanities Clinical Trial Non-degree Award
Peter Olupot-Olupot Olupot
ID: UNCST-2020-R014798
 SMAART-MAP trial Severe Malaria A Research and Trials consortium - Multisite Adaptive Platform trial
REFNo: HS4547ES

OBJECTIVES
The objective of the SMAART-MAP trial is to identify promising adjunctive therapies to take forward into a large Phase III trial in severe malaria with a mortality endpoint. The adaptive platform design enables additional domains to be added so a range of adjunctive therapies can be tested, across multiple clinical presentations of severe malaria, in a timely manner.

PRIMARY OBJECTIVE(S)
To explore within each domain the therapeutic efficacy of the intervention using an early indicator such as a biomarker or clinical assessment at 24-72 hours.

SECONDARY OBJECTIVE(S)
 To assess the impact of the interventions on clinical outcomes (readmission and
mortality) on all children 28 days and 90 days after randomization
 To assess the impact of the interventions on Grade 3 or 4 adverse events, and adverse
events of any grade related to the interventions or comparators.
 To assess the impact of proposed definitions for severe malaria based on platelet counts
≤150,000/µL and plasma pfHRP2 concentrations ≥800 ng/mL on differences between
randomized groups
 In a sub study, to determine the performance characteristics of a POC pfHRP2 test
compared with quantitative plasma pfHRP2 concentrations determined from plasma.

 Uganda 2024-08-16 11:01:14 2027-08-16 Medical and Health Sciences Clinical Trial Non-degree Award
SYLVIE NAMWASE
ID: UNCST-2024-R003958
 Charcoal Conflict in Climate Change’s Decarbonisation Dilemmas: Knots of Livelihood, Nutrition, Communities, Gender, Migration and Energy in East Africa. RefNo: CoBAMS-REC-2024-39
REFNo: SS2909ES

To examine the East African challenges in the context of the global political landscape of climate strategies and identify how success-criteria are derived from global dynamics, and what lessons from these local cases should be fed into global policy-making.,To identify and examine the ways in which Uganda and Tanzania have initiated local solutions to the charcoal and climate change crisis and how they can each harmonise their legal and policy framework change in a way that is responsive to their local realities while in tandem with global climate change and decarbonisation trends.,To understand the legal and policy frameworks governing the climate change, charcoal and decarbonisation dilemma in Uganda and Tanzania. ,To understand local processes of charcoal transition in Uganda and Tanzania in order to capture the impact of possible changes on livelihoods, food, nutrition and health as well as social stability, and relations among different social identity groups, where gender, youth, women and migration are particularly central. ,The main objective is to understand how global climate change mitigation policies (decarbonisation) condition charcoal politics and socio-economic dynamics in energy-stressed countries down to local levels, and how to manage conflicts.,
 Uganda 2024-08-12 10:56:54 2027-08-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
PATRICIA  ATUKUNDA
ID:
Staff Welfare Strategies and Performance of Healthcare Providers in Government -aided Health Facilities in Bushenyi District, Uganda
REFNo: SS2783ES

To find out the extent to which career growth strategy affects the performance of healthcare givers in government-aided health facilities in Bushenyi District, Uganda.,To determine the extent to which financial well-being strategy impacts the performance of healthcare workers in government-aided health facilities in Bushenyi District, Uganda,To establish the extent to which work-life balance strategy influences the performance of healthcare workers in government-aided health facilities in Bushenyi District, Uganda.,To assess the extent to which health and safety strategy influences the performance of healthcare givers in government-aided health facilities in Bushenyi District, Uganda.,To analyze how the well-being of staff influences the performance of healthcare givers in government-aided health facilities within Bushenyi District, Uganda.,
 Uganda 2024-08-12 10:55:47 2027-08-12 Social Science and Humanities Non-Clinical Trial Degree Award
CAROLINE NAKIDDE KAVUMA
ID:
Influence of Indigenous and Contemporary Early Years’ Education Pedagogy on Development of Children’s life-skills, Masaka District-Uganda
REFNo: SS2888ES

1.To establish the influence of indigenous pedagogy on the development of life skills among their children.
2.To investigate the influence of contemporary Early Years’ Education Pedagogy on the development of life skills among Baganda children.
3.To establish the influence of indigenous and contemporary EYE pedagogy on life skills development among children.
4.To examine the difference between the influence of IP and contemporary EYE pedagogy in development of life skills among Baganda children.

 Uganda 2024-08-06 18:26:29 2027-08-06 Social Science and Humanities Non-Clinical Trial Degree Award
Julia Mwesigwa Nanteza
ID:
Perceptions, attitudes and Information needs of Stakeholder, Health Worker, and Child Caregiver to guide introduction of the Malaria Vaccine in Uganda
REFNo: SS2895ES

1. Assess participants’ awareness of the MV, including identification of Malaria Vaccine information sources. 2. Ascertain the misconceptions, fears, and rumors from the public about the Malaria Vaccine. 3. Elicit participant concerns about side effects of the Malaria Vaccine. 4. Ascertain participant expectations for Malaria Vaccine efficacy and acceptability of continued bed net use with vaccinated children. 5. Assess caregivers’ acceptability of adhering to a four-dose vaccination schedule that extends into the second year of life and may involve new vaccination visits. 6. Identify health workers’ perceived challenges for client education, provision of a four-dose schedule, tracking dose delivery, and reporting. 7. Elicit national and subnational stakeholder views and recommendations for a successful introduction of the Malaria Vaccine, including recommendations about effective ways to link and integrate UNEPI and National Malaria Control Program (NMCP) activities to promote and provide the MV.
Uganda 2024-08-06 18:24:50 2027-08-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
NAKANWAGI JOSLYLINE LYDIA
ID:
A comparative analysis of adherence, retention in care, and viral suppression among PLHIV aged 50 and above and below 50 at Mulago ISS Clinic, Uganda.
REFNo: HS4587ES

To understand the psychosocial needs and challenges (stigma, social support, mental health and lifestyle adjustments faced by PLHIV aged 50 years and above attending Mulago ISS Clinic.,To determine the factors associated with adherence to ART, retention in care and viral suppression among people aged 50 years and above,o compare adherence to ART, retention in care and viral suppression of PLHIV aged 50 years and above and those below 50 years attending Mulago ISS clinic,To compare the cascade of care between people living with HIV aged 50 years and older and those below 50 years at Mulago ISS clinic in Uganda.,
 Uganda 2024-08-06 18:14:04 2027-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HARRIET NAMBUYA NIL
ID: UNCST-2021-R013414
 World Health Organization Minimum Maternal and Newborn Health Data Set: pilot study at Jinja Regional Referral Hospital
REFNo: HS4727ES

General objective
The aim of the study is to assess the baseline capacity of collecting the data elements to inform WHO mMNHDS at hospitals in low- and middle-income countries.
Specific objectives
1.To identify which data elements of WHO mMNHDS are already incorporated into the hospitals’ existing data systems.
2.To determine which data elements of WHO mMNHDS create the largest challenges for incorporation within hospitals’ routine data collection efforts.
3.To determine which data elements can be used to inform future implementation strategy of WHO mMNHDS.
4.To determine which data elements can be used to inform subsequent revisions of the WHO mMNHDS.

 Uganda 2024-08-06 18:12:03 2027-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Issa Ndungo
ID: UNCST-2024-R004235
 The Interplay among Instructional Strategies, Learners Geometry Attitudes, and Van Hiele Levels of Geometric Reasoning: A Case Study of Selected Secondary Schools in Mid-Western Uganda.
REFNo: SS2857ES

To determine the Mediating Role of Geometry Attitudes on the relationship Between Instructional Strategies and Progression Through Van Hiele Levels,To compare the Effect of Instructional Strategies on learners’ Progression Through Van Hiele Levels,To investigate the relationship between Geometry Attitudes on learners’ Progression Through Van Hiele Levels,To compare the influence of Instructional Strategies on Learners\' Geometry Attitudes.,To investigate the relationship between instructional strategies, learners\' attitudes toward geometry, and their Van Hiele levels of geometric reasoning.,
 Uganda 2024-08-06 18:10:09 2027-08-06 Social Science and Humanities Non-Clinical Trial Degree Award
jonathan sserunkuuma
ID:
Readiness of health facilities to diagnose, manage, and prevent the Ebola epidemic along Border districts in Southwestern Uganda.
REFNo: HS4575ES

To assess the capacity and readiness of primary healthcare centers to diagnose Ebola virus disease in Southwestern Uganda.To assess the capacity and readiness of primary healthcare centers to manage Ebola virus disease in Southwestern Uganda.To assess the capacity and readiness of primary healthcare centers to prevention Ebola virus disease in Southwestern Uganda.
 Uganda 2024-08-06 18:07:39 2027-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Ninsiima Connie
ID:
Prevalence, Predictors, and Outcomes of Non-Communicable Diseases (Hypertension, Diabetes Mellitus, Obesity and Mental Health Disorders) among Persons Living with HIV in Uganda
REFNo: HS4621ES

To document the health-system-related strengths, opportunities, and challenges in the provision of NCDs services among PLHIV in Uganda,To describe the HIV and NCD outcomes for PLHIV with the selected NCDs in Uganda.,To document factors that are associated with selected NCDs among PLHIV in Uganda.,To describe cascades of care for selected NCDs among PLHIV in Uganda.,To describe the burden, predictors and outcomes of NCDs among PLHIV in Uganda, and assess the capacity of the Ugandan health system to offer NCDs services to PLHIV.,
 Uganda 2024-08-06 18:04:20 2027-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
VINCENT MUBANGIZI
ID: UNCST-2024-R004232
 Opti-MaP (Optimising Implementation of Maternal and Perinatal Death Surveillance and Response to prevent avoidable future deaths in Uganda
REFNo: HS4630ES

To review existing tools, develop and adapt a harmonised toolbox of resources to optimise MPDSR implementationTo co-design customised an "intervention package" using the toolboxTo evaluate effectiveness and cost-effectiveness of the "customised intervention package" to reduce perinatal and maternal mortalityTo develop and adapt a harmonised toolbox of resources to optimise MPDSR implementation
 Uganda 2024-08-06 18:02:24 2027-08-06 Medical and Health Sciences Clinical Trial Non-degree Award
Rawlance  Ndejjo
ID: UNCST-2022-R010993
 City-based interventions to stimulate active movement for health (CITY-MOVE) in Kampala city, Uganda
REFNo: HS4566ES

5. To assess the effects of selected city interventions on physical activity and population health and wellbeing. ,4. To document population & spatial data availability and assess utilization of routine physical activity data in Kampala city.,3. To identify stakeholder needs, preferences, and feasibility of selected early-phase city-GAPPA interventions to support their successful implementation through action research in LLs. ,2. To describe selected GAPPA interventions in Kampala city and evaluate their implementation process. ,1. To develop a comprehensive theory of change and operationalized measures for stakeholder engagement and context analysis in Kampala city,The primary aim of this study is to comprehensively evaluate the impact and long-term viability of city-GAPPA interventions aimed at promoting active movement and generate evidence on implementation, evaluation, and scalability as well as best implementation practices and transferability of city-GAPPA interventions,
 Uganda 2024-08-06 17:55:51 2027-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ezekiel  Musasizi
ID: UNCST-2024-R005085
 DETERMINANTS OF ADHERENCE TO NICOTINE REPLACEMENT THERAPY AMONG PEOPLE LIVING WITH HIV USING SMOKELESS AND SMOKED TOBACCO IN ARUA AND MOROTO DISTRICTS OF UGANDA
REFNo: HS4478ES

4. To explore experiences of People Living with HIV on ART in using Nicotine Replacement Therapy patches,3. To determine the interpersonal and intrapersonal factors associated with adherence to NRT among PLWH on ART who use smokeless and smoked tobacco enrolled to the Quit4Life+ trial. ,2. To explore the organizational and community factors influencing smokeless and smoked tobacco use among PLWH on ART in Arua and Moroto districts in Uganda ,1. To determine the intrapersonal and interpersonal factors influencing smokeless and smoked tobacco use among People Living with HIV on ART in Arua and Moroto districts in Uganda ,To determine the intrapersonal, interpersonal, organizational, and community determinants of smokeless and smoked tobacco use and NRT adherence among People Living with HIV on ART in Arua and Moroto districts in Uganda,
 Uganda 2024-08-06 17:52:34 2027-08-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Epidemiology of Acute Respiratory Illness in Southwestern Uganda: A Retrospective Review
REFNo: HS4543ES

The primary objective of this study is to retrospectively document epidemiological and ecological trends in both outpatient and inpatient cases of ARI in five districts in southwestern Uganda. These data will inform the establishment of a network of healthcare facilities to conduct research on preventing and improving the management of ARI in this region.,
 Uganda 2024-08-06 17:47:55 2027-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David  Mwambari
ID:
Traveling Memories, Silences and Secrets (TMSS): Life narratives of Violence Among Refugees from Africa’s Great Lakes Region – A case of Uganda
REFNo: SS2424ES

The study will be guided by the following objectives: 1. Empirically: (a) to map and examine how the life narratives of refugees evolve from contexts of origin to countries of transition and destination (Burundi⇒Tanzania⇒USA;
DRC⇒Uganda⇒Belgium; Rwanda⇒Kenya⇒South Africa); (b) to investigate the evolution
of the memories, silences, and secrets that AGLR refugees carry in their trajectories of
migration.
2. Theoretically: to analyse (a) how space and time transform these life narratives on the move, and (b) how these transformed life narratives shape relationships within refugee communities and relationships with host communities in countries of transition and destination.
3. Epistemologically: (a) to develop a set of innovative interdisciplinary perspectives and
methodological approaches that can be used in researching the memory dynamics and mobility
that originate from Global South lived experiences; (b) to foster collaboration between a diverse multidisciplinary, international team of researchers involved in the TMSS project.
4. Policy: to explore how (a) our understanding of life narratives on the move can transform policy-making at local, regional, and international levels; and (b) how this understanding shapes practitioners’ work with refugees in countries of transition and destination.
 Belgium 2024-08-06 17:46:31 2027-08-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Implementation research on the tailored, multidisciplinary Non-Communicable Disease prevention package targeting air pollution exposure in mid- to late adolescents in Uganda: FRESHAIR-4-LIFE
REFNo: SS2485ES

To address the burden of NCDs by gaining knowledge, resources and capacity to optimize the implementation of tailored preventive intervention packages, targeting adolescents’ exposure to risk factors like tobacco (use) and AP in disadvantaged populations worldwide. In Uganda, we will focus on air pollution.,
 Uganda 2024-08-06 17:44:22 2027-08-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aurelius  Ssali Ssettunba
ID: UNCST-2023-R005538
 CHARISMS OF INSTITUTES OF CONSECRATED LIFE AND THE MISSIONS OF CONSECRATED PERSONS OF THE SELECTED FOUR INSTITUTES IN UGANDA.
REFNo: SS2647ES

specific objectives of the study The study seeks to focus on.the following objectives 1. To find out whether the four institutes of the Concreted life in Uganda do assimilate their founders’ Charisms. 2. To evaluate the areas of pastoral activities that fulfillstheir Founders’Charisms. 3. To identify challenges experienced by the different institutions in their fulfillment of their founders Charisms.,To identify the relationship between charism and mission in the consecrated institutions.,To evaluate the areas of pastoral activities that fulfills their Founders‟Charisms.,To find out whether Personal charism leads to Restore God‟s glory among people in the charism institution. ,Basing on the study, it will establish whether the four members institutes of the consecrated do effectively assimilate their Charism to effectively do their mission,
 Uganda 2024-08-06 17:42:37 2027-08-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Abubaker Kawooya
ID:
PHAGE-MEDIATED BIOCONTROL OF THE DOMINANT PATHOGENIC BACTERIA STRAIN IN READY-TO-EAT VEGETABLE SALADS SOLD IN KAMPALA CITY
REFNo: HS3986ES

To study the safety of phages by analyzing the entire genome sequence for unwanted genes,To determine the lytic activity of phages against the dominant pathogenic bacteria isolated from ready-to-eat vegetable salads,To establish the diversity and genetic relatedness of bacteria in ready-to-eat vegetable salads,This study aims to evaluate the effectiveness of Phages in maintaining the microbial quality of ready-to-eat vegetable salads in Kampala.,
 Uganda 2024-08-06 17:40:09 2027-08-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Ismail  Draguma Legason
ID: UNCST-2021-R012130
 Immunohistochemical assessment of Epstein Barr virus-encoded nuclear antigen (EBNA-1)and selected lymphoma markers for Burkitt Lymphoma diagnosis in resource-restricted settings
REFNo: HS4755ES

To determine the combined sensitivity, specificity, and predictive values of EBNA-1immunohistochemistry with CD10, BCL2, and Ki67 for the diagnosis of Burkitt lymphoma.,To determine the sensitivity, specificity, and predictive values of EBNA-1 protein immunohistochemistry for diagnosing Burkitt lymphoma. ,To evaluate EBNA -1 and selected lymphoma markers for Burkitt lymphoma diagnosis in resource-limited settings. ,
 Uganda 2024-08-06 17:39:05 2027-08-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Johnes Obungoloch
ID: UNCST-2024-R005331
 Application of Artificial Intelligence using Chest x-ray images to aid clinical care of patients with pulmonary complications in Uganda (AI4CX)
REFNo: SS2718ES

III.To develop a machine learning algorithm for automated diagnosis of pulmonary diseases from chest x-ray images,II.To establish a dataset of annotated chest x-ray images of pulmonary diseases among patients seeking pulmonary care in Mbarara City, South Western Uganda,I.To generate quality chest x-ray images of pulmonary diseases among patients seeking care in Mbarara City, South Western Uganda,●To develop an Artificial intelligence model using Chest x-ray images to aid clinical care of patients with pulmonary complications in Uganda,
 Uganda 2024-08-06 17:38:06 2027-08-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
ABDULAZIZ KAKOOZA
ID: UNCST-2024-R004009
 INTEGRATION OF EMPLOYABILITY SKILLS IN PRE-SERVICE TEACHER TRAINING PROGRAMME IN HIGHER EDUCATION INSTITUTIONS IN UGANDA: A CASE STUDY OF KYAMBOGO UNIVERSITY
REFNo: SS2747ES

iii. To establish ways employability skills can be enhanced in the pre-service teacher training programme at Kyambogo University. ,ii. To examine the integration of employability skills in the pre-service teacher training programme at Kyambogo University.,i. To explore employability skills desired by employers from pre-service teacher training graduates at Kyambogo University.,
 Uganda 2024-08-06 17:36:01 2027-08-06 Social Science and Humanities Non-Clinical Trial Degree Award
Arthur Kwizera
ID: UNCST-2021-R012928
 A multicentre, prospective, registry-based intensive care quality improvement project in Uganda’s hospitals.
REFNo: HS4484ES

To inform clinical guidelines, national policies and planning for critical care services in Uganda. ,To describe the epidemiology and outcomes of intensive care patients in Uganda,To implement a national intensive care registry that can be used at both a facility, and national level to assess, report and improve quality of care for intensive care unit patients. ,
 Uganda 2024-08-06 17:34:41 2027-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 A Phase 4, Open-Label, Rollover Study to Provide Continued Access to Cabotegravir Long-acting Injection and Rilpivirine Long-acting Injection to Participants Living with Human Immunodeficiency Virus Type 1 (HIV-1) Infection Who Participated in Long-Acting Combination Therapy Studies.
REFNo: HS4452ES

The secondary objective is to assess the long-term safety and tolerability of CAB LA + RPV LA by evaluating the incidence of serious adverse events (SAEs), pregnancies, adverse events (AEs) leading to discontinuation of CABLA +RPV LA, and AEs considered to be related to the study intervention.,The primary objective of the study is to provide continued CAB LA + RPV LA access to participants who were enrolled and treated with CAB LA + RPV LA in the parent studies, and who, at the time of roll-over, experience and are expected to continue to experience clinical benefit from this treatment.,
 Uganda 2024-08-06 17:32:50 2027-08-06 Medical and Health Sciences Clinical Trial Non-degree Award
alfred bulamu
ID: UNCST-2023-R008638
 Uganda Translational Breast Cancer Screening Research Center with Innovations in MRI and Genetic Testing.
REFNo: HS4689ES

Implementation of breast MRI with genetic testing as BC screening method for women at high risk of BC by July 2029 (Phase 6) , Continuous Trainings for radiologists, radiographers and laboratory staffs on the modern technologies of MRI and Genetic testing (phase 3 to phase 6) ,Evaluating the feasibility of screening BC using MRI and genetic testing for high risk women by December 2028 (phase 5),Large scale education of the community about BC by July 2028 (phase 3 and phase 4).,Large scale determination of the utility of genetic testing as a screening modality for BC in Uganda by perform mutational genetic analysis for women at high-risk aged19 years to 80 years by July 2028 (phase 3 and phase 4) , Large scale determination of the utility of quantitative breast MRI for screening women at high risk BC aged 19 years to 80 years by July 2028 (phase 3 and phase 4) ,Training of the users on equipment i.e. Radiologists, Radiographers and laboratory staffs by 2025 (phase 2) ,Securing and installation of lab equipment for genetic testing by 2025 (Phase 2,Securing and installation of MRI with Breast coils by July 2025 (Phase 2),To build capacity for 20 laboratory health care workers in genetic testing technologies by December 2023 (phase 1).,To build capacity for 30 radiology health professionals in modern breast Imaging with MRI by December 2023 (Phase 1),To determine the utility of quantitative breast MRI for screening women at high risk breast cancer aged 19 years to 80 years by July 2024 (phase 1),To determine the utility of genetic testing as a screening modality for BC in Uganda by perform mutational genetic analysis for women at high-risk of BC aged 19 years to 80 years, by July 2024 (phase1),To build a long-lasting infrastructure for research, clinical screening in Uganda and training using modern technologies. ,To offer improved access to Breast Cancer screening in Uganda through quantitative MRI and genetic testing research center,
 Uganda 2024-08-06 17:27:31 2027-08-06 Medical and Health Sciences Clinical Trial Non-degree Award
Edward Nahurira
ID: UNCST-2022-R009739
 Comparative Phytochemical Studies of Callus Regenerated from Leaf Explant of Prunus Africana (Hook F. Kalkman) and Stem Bark of the Same Mother Plant
REFNo: HS2434ES

1. To develop callus culture from the explant of P. africana leaf and stem bark.

2. To evaluate the phytochemical constituents of the callus extracts of P. africana leaf and stem bark explant.

3. To develop and compare the TLC and HPLC fingerprints of each extract for their identification.

 Uganda 2024-08-06 17:22:37 2027-08-06 Medical and Health Sciences Non-Clinical Trial Degree Award
ANITA ARINDA
ID: UNCST-2020-R014158
 Intellectual Disability in Children and Adolescents with Epilepsy in Mulago and Butabika National Referral Hospitals: Prevalence and Associated Factors
REFNo: HS4589ES

2. To determine the factors associated with ID in children and adolescents with epilepsy attending Mulago and Butabika National Referral Hospitals.,1. To determine the prevalence of ID in children and adolescents with epilepsy attending Mulago and Butabika National Referral Hospitals.,To determine the prevalence of and factors associated with ID in children and adolescents with epilepsy attending Mulago and Butabika National Referral Hospitals.,
 Uganda 2024-08-05 14:04:37 2027-08-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Oketch
ID: UNCST-2024-R004313
 Long-Term Impacts of Improved Childhood Literacy
REFNo: SS2796ES

Economic situation,
 UK 2024-08-05 14:01:33 2027-08-05 Social Science and Humanities Clinical Trial Non-degree Award
Jonathan Mayito
ID: UNCST-2019-R000490
 Detection of Mycobacterium tuberculosis in blood of tuberculosis patients and their contacts in Uganda
REFNo: HS4553ES

To determine whether Mtb strains isolated from the sputum/blood of index cases with pulmonary TB are genetically identical to those detected in the blood of their contacts,To establish whether detection of Mtb in blood using the methods above associates with either of the following biomarkers of host immune response: - QFT-Plus - Blood RNA signatures for incipient tuberculosis,To determine whether Mtb can be detected in the blood of TB patients and their contacts, recruited in Kampala, Uganda, using any of the following methods: - GeneXpert® MTB/RIF Ultra (Cepheid) - Fluorescence microscopy - Blood culture - Targeted Next-Generation Sequencing,The primary objective of this study is to determine whether Mtb DNA can be detected in the blood of TB patients and their contacts, recruited in Kampala, Uganda, using digital PCR,
 Uganda 2024-08-05 13:49:07 2027-08-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
OKELLO DAMOI JOSEPH
ID: UNCST-2022-R011560
 Construction and Validation of a Poverty Assessment Survey Tool to Inform Ambulatory Care and Surgery Cost Waiver or Subsidization in a Developing Country
REFNo: HS4463ES

To determine the weights of each attribute per item, in the constructed and validated tool that can be used to inform ambulatory care and surgery cost waiver or subsidization in a developing country,To construct a validated ambulatory care and surgery-context poverty assessment survey tool that can be used to inform ambulatory care and surgery cost waiver or subsidization in a developing country,To analyze the data earlier collected using the ambulatory care and surgery-context poverty assessment survey tool at KSC, for principal components,To conduct content validity and reliability testing of the ambulatory care and surgery- context poverty assessment survey tool, previously developed with adaption of some items from the simple poverty score tool for Uganda,To construct and validation of a poverty assessment survey tool that can be used to inform ambulatory care and surgery cost waiver or subsidization in a developing country,
 Uganda 2024-08-05 13:12:56 2027-08-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Vesall Nourani
ID: UNCST-2022-R009221
 Impact of on-demand irrigation service : Evidence from Uganda
REFNo: SS2112ES

Do certain intermediaries (providers of agricultural inputs) facilitate efficient information aggregation and dissemination of farming knowledge between farmers?,
 USA 2024-08-05 13:11:25 2027-08-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Lawrence Okidi
ID:
NUTRITIONAL QUALITY AND MICROBIAL SAFETY OF SELECTED INDIGENOUS FOODS FOR CHILDREN UNDER FIVE: A CASE STUDY OF KARAMOJA SUB-REGION OF UGANDA
REFNo: A51ES

1.3 Objectives
1.3.1 General objective
To contribute to food security by investigating the nutritive quality and safety of indigenous foods for children under five in Karamoja sub-region.
1.3.2 Specific objectives
i. To assess household handling practices of selected indigenous foods for children under five in Karamoja sub-region
ii. To determine the nutritional quality of selected indigenous foods for children under five in Karamoja sub-region
iii. To determine the microbial load and diversity of selected indigenous foods for children under five in Karamoja sub-region
iv. To determine the dietary exposure risk of children under five to pathogenic microorganisms from selected indigenous foods in Karamoja sub-region

 Uganda 2024-08-02 17:46:01 2027-08-02 Agricultural Sciences Degree Award
Charles Masembe Kikubo
ID: UNCST-2019-R001092
 Investigating the dynamics and clinical outcome of African swine fever infection at pig farms in an endemic livestock wildlife setting in Uganda
REFNo: A355ES

1) Assess the spatial distribution of pig farmers in the study areas and recruit them
2) Determine the ASF virus molecular characteristics in apparently healthy domestic pigs
3) Determine the genetic characteristics and relationships of ASFV isolated from domestic pigs
4) Determine the full genome characteristics of the unique lineages obtained from domestic pigs
5) To establish an ASF biobank of clinical materials that are curated with clinical outcomes
6) Establish Ugandan Genotype IX repository at PIADC - for genomics and vaccine research
7) Build rapid ASF whole genome sequencing capacity in endemic settings

 Uganda 2024-08-01 16:54:11 2027-08-01 Agricultural Sciences Non-Clinical Trial Non-degree Award
David Kibirige
ID:
DESIGN AND IMPLEMENTATION OF A PV SYSTEM FOR EMERGENCY SITUATION IN HEALTH FACILITIES IN RWEBISENGO UGANDA
REFNo: SIR363ES

4. To carryout hardware design and field test of the PV system,3. To design an improved inverter system for both AC single phase and three phase for PV application.,2. To model a PV power system circuit using Proteus software as well as carrying out its dynamic modeling using Simulink,1. To carry out Electrical and thermal analysis of a PV system to be used during the study,The aim of this research is to design a PV system that can be utilized during emergency situation in health facilities in Rwebisengo Uganda.,
 Uganda 2024-08-01 16:05:23 2027-08-01 Engineering and Technology Non-Clinical Trial Degree Award
EDWINAH ATUSINGWIZE
ID: UNCST-2023-R007893
 Exploring Stakeholder perspectives of the social determinants of malaria in Uganda
REFNo: HS4271ES

3. To explore barriers and facilitators to addressing the social determinants of malaria.,2. To examine how the social determinants of malaria are addressed in policy making and practice. ,1. To explore stakeholder perspectives of the social determinants of malaria.,The overall aim of this study is to explore stakeholder perspectives and experiences of the social determinants of malaria in Uganda in order to inform malaria prevention policy and practice. ,
 Uganda 2024-07-26 16:04:20 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alen Musisi
ID: UNCST-2022-R009338
 Knowledge, Attitude, and Practice on Radiation Protection Among Radiation Safety Officers in Uganda.
REFNo: HS4617ES

To determine the radiation protection knowledge level among RSOs
To determine the level of attitudes of RSOs towards radiation protection and safety
To determine radiation protection practices among RSOs

 Uganda 2024-07-26 16:03:08 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jean Damascene Niyonsenga
ID:
Role of PT in Ugandan Neurosurgical Transitional Care
REFNo: HS4400ES

This study aims to determine acceptability and feasibility of utilizing an interdisciplinary discharge planning protocol to improve team communication and increase patient referral to outpatient rehabilitation services in two public Ugandan hospitals.
 Rwanda 2024-07-26 16:01:48 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mbisi Muhindo Enosh
ID:
HOST COMMUNITIES’ RELATIONS AND REFUGEE ADAPTABILITY AT KYAKA II AND KYANGWALI SETTLEMENTS IN WESTERN UGANDA
REFNo: SS2953ES

To examine the role of social cohesion within host communities in facilitating refugee adaptability at Kyaka II and Kyangwali settlements,To investigate how Attitudes and Perceptions of host communities influence Refugee Adaptability at Kyaka II and Kyangwali settlements,To assess the socio-economic and political factors contributing to refugee adaptability at Kyaka II and Kyangwali settlements,To examine the impact of legal and policy framework on Refugee Adaptability within Host communities at Kyaka II and Kyangwali settlements in Uganda,To examine the dynamics and factors influencing the relationship between host communities and refugees, and to understand the impact of this relationship on the adaptability and integration of refugees at Kyaka II and Kyangwali settlements,
 Uganda 2024-07-26 15:59:56 2027-07-26 Social Science and Humanities Non-Clinical Trial Degree Award
Doris Kwesiga
ID:
Implementer’s Voices: An input to the Lancet Commission on Evidence-based Implementation in Global Health
REFNo: HS4408ES

To examine the insights and experiences of LMIC health sector implementers on the use of evidence in their work, so as to identify barriers and enablers and design interventions to increase evidence-based implementation.,ii. What are the gaps between evidence and implementation, and how can these be closed?,i. How and why, do (or don’t) implementers use evidence? ,
 Uganda 2024-07-26 15:58:42 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ismail  Draguma Legason
ID: UNCST-2021-R012130
 Molecular profiling of Epstein-Barr virus genome and expression in endemic Burkitt Lymphoma (EBVL study)
REFNo: HS4198ES

1. The main goal of the study is to examine the molecular architecture of EBV, its expression pattern, and the determinants of viral pathogenesis in endemic Burkitt lymphoma. ,Perform differential gene expression and protein analysis on formalin fixed-paraffin embedded BL tissues using RT- PCR or NanoString and analyse the data for: i) differentially expressed genes and proteins ii) gene and protein expression levels iii) correlation with tumour stage and viral strains ,Perform whole genome sequencing of EBV from clinical samples (ctDNA for eBL and plasma for healthy controls) and analyse data for: i) viral strains and co-infection ii) Mutations (SNVs, Indels, and structural variants) and compare frequencies iii) mutational signatures iv) viral population structure -phylogenetics and decomposition matrices to infer evolutionary relatedness with publicly available strains. ,
 Uganda 2024-07-26 15:56:08 2027-07-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Sarah  Mayanja
ID:
Effect of the Triple S technology on farmers' food security in northern and eastern Uganda
REFNo: A438ES

3. To compare the extent to which sweetpotato augments smallholder’s food availability amongst users and non-users of the Triple S technology ,2. To assess the values which motivate use and uptake of the Triple S technology by smallholder farmers,1. To compare the Knowledge, Attitudes and Perceptions towards the Triple S technology by users and non-users of the technology ,Overall objective: To assess the contribution of the ‘Triple S’ technology on farmers food security in the northern and eastern regions of Uganda.,
 Uganda 2024-07-26 15:54:12 2027-07-26 Agricultural Sciences Non-Clinical Trial Degree Award
Adam Lichtenheld
ID: UNCST-2024-R004326
 Re:Build – Building Business and Social Networks to Strengthen Refugee Economic and Social Integration
REFNo: SS2803ES

The effect of the intervention on approaches of collaboration and information sharing,The effect of the intervention on psychological and social dimensions for each individual,The effect of the intervention on business outcomes (profit, savings, business growth),The effect of the intervention on network constellations in participants’ egocentric business networks,1. How can interventions support the development of business networks for refugees and nationals in urban markets of developing countries? ,
 USA 2024-07-26 15:50:47 2027-07-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Kaweesa
ID:
THE EFFICACY OF BIOCHAR AND VERMICOMPOSTS INTEGRATED WITH NPK BLENDED FERTILIZER ON SOIL BIOCHEMICAL PROPERTIES, NUTRIENT USE EFFICIENCY, YIELD AND GRAIN QUALITY OF UPLAND RICE (Oryza Sativa L.) IN CENTRAL UGANDA
REFNo: A447ES

To contribute to improved food security by increasing upland rice yields through optimizing fertilizer use efficiency using biochar and vermicomposts in central Ugandai. To ascertain the effect of Biochar and the different rates of NPK blended fertilizers integrated with VCs on growth and yield of upland riceii. To ascertain the effect of Biochar and the different rates of NPK blended fertilizers integrated with diverse VCs on selected soil biochemical properties. iii. To ascertain the effect of Biochar and the different rates of NPK blended fertilizers integrated with diverse VCs on nitrogen and phosphorus use efficiencies and uptakes in upland rice productioniv. To ascertain the effect of biochar and different rates of NPK blended fertilizers integrated with diverse VCs on selected nutritional qualities of upland rice grains.
 Uganda 2024-07-26 15:48:47 2027-07-26 Agricultural Sciences Non-Clinical Trial Degree Award
Sarah Kiguli
ID: UNCST-2021-R013020
 In-Hospital Mortality Among Sickle-Cell Disease Patients with and without SARS-CoV-2 co-Infection at Mulago National referral Hospital.
REFNo: HS4253ES

Genral OBJECTIVE
The overall objective of this study is to determine the in-hospital annual mortality rate among SCD patients over the 2010 to 2022 13 years period, and the association with SARS-CoV-2 infection-related morbidity and mortality in Uganda.

SPECIFIC OBJECTIVES
1.To determine prevalent SCD events and time-trend (annual) of in-hospital mortality rate before the COVID-19 pandemic (2010 to 20190) at Mulago National referral & Teaching Hospital
2. To assess probable-cause of death by adjudicating the diagnosis made at the time of death
3. To investigate the individual and health system factors (e.g., pediatricians with SCD expertise, pediatric ICU, oxygen supply, blood bank, and access to Hydroxyurea) associated with in-hospital mortality
4. To assess the prevalence of SARS-CoV-2 infection and any bidirectional effect between SARS-CoV-2 and SCD on mortality among those with vs. without SARS-CoV-2 or SCD admitted in hospital between 2020 and 2022.


 Uganda 2024-07-26 15:47:47 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Leveraging Molecular Technologies to Improve Diagnosis and Management of Pediatric Acute Respiratory Illness in Resource-Constrained Settings.
REFNo: HS4539ES

Refine existing host immune response classifiers for the differentiation of bacterial and viral causes of febrile ARI among children in Uganda. Determine the etiology of febrile ARI episodes using a diagnostic assessment that includes physician adjudication and is augmented by pathogen metagenomics. Develop and internally validate a host immune response signature that differentiates between causes of pediatric ARI in Uganda using previously identified gene transcripts. Develop novel clinical algorithms for pediatric ARI to inform antibiotic treatment decisions ,The objective of this proposal is to develop novel clinical algorithms for pediatric febrile ARI in sub-Saharan Africa to identify children with bacterial illness. To augment samples collected during a previous cohort study (MUST REC 14/03-19) to achieve sufficient sample size to develop a host gene expression signature that differentiates between viral and bacterial ARI, we will enroll 160 children presenting to St. Pauls Health Center IV with ARI and 20 healthy controls.,
 Uganda 2024-07-26 15:44:44 2027-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
 UNDERSTANDING DRIVERS OF TB AND MALARIA PREVALENCE AND INCIDENCE, AND BARRIERS TO UPTAKE OF HEALTH SERVICES AND RETENTION IN CARE – COMMUNITY VOICE PERSPECTIVE IN NAMAYINGO DISTRICT
REFNo: SS2915ES

To collaboratively develop recommendations for driving sustainable impact and improving health outcomes in the context of TB and malaria.,To identify community-specific needs and gaps in current TB and malaria interventions and healthcare delivery systems.,To explore the socio-economic, cultural, and behavioral factors influencing the spread and persistence of TB and malaria within communities.,To engage directly with community members to understand their perspectives on the barriers and drivers of TB and malaria prevalence and incidence.,To understand the drivers of TB and malaria prevalence and incidence, as well as barriers to the uptake of health services and retention in care from a community voice perspective in Namayingo district,
 Uganda 2024-07-26 15:43:11 2027-07-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
William  Veness Andrew
ID:
Assessing Causal Processes of Multi-Hazard Risk in the Rwenzori Region
REFNo: NS842ES

Generation of an evidence base for solutions through a multi-hazard risk assessment inthe Rwenzori Mountains
Hydrological characterisation of the highlands
Evidencing the mechanisms of landslides and potential for vegetative stabilisation
Evidencing geomorphological changes in river valleys
Assessment of whether water quality is being impacted by soil erosion
 UK 2024-07-26 15:42:01 2027-07-26 Natural Sciences Non-Clinical Trial Degree Award
Ronald Angupale Jimmy
ID:
Design, Development and Characterization of Drug Delivery Systems for Ugandan Antimalarial Plants - Artemisia annua, Vernonia amygdalina and Microglossa pyrifolia
REFNo: HS1886ES

4. To optimize the developed drug delivery system(s) with respect to the critical product quality attributes and assess their antimalarial efficacy and safety,3. To design and develop suitable herbal drug delivery systems (conventional and novel) for the plant extracts,2. To carry out preformulation studies (physicochemical properties) for the plant extracts,1. To determine in vivo antimalarial efficacy of selected combinations of A. annua, V. amygdalina and M. pyrifolia ,To design, develop and characterize drug delivery systems for selected Ugandan antimalarial plants – Artemisia annua, Vernonia amygdalina and Microglossa pyrifolia,
 Uganda 2024-07-26 13:50:14 2027-07-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
 Outcomes of paediatric inguinal hernia repair performed by surgeons versus medical officers
REFNo: HS4508ES

Calculate and compare costs and cost-effectiveness between the two groups. ,Compare patient related outcomes between the group that has been operated on by medical officers versus those who were operated by general surgeons. ,The general objective of the proposed study is to investigate the possibility of task sharing between general surgeons and medical officers in inguinal hernia repair in children in Uganda. ,
 Sweden 2024-07-23 15:30:50 2027-07-23 Medical and Health Sciences Clinical Trial Degree Award
Immaculate  Atukunda
ID: UNCST-2021-R013573
 EVALUATION OF A NEW LOW-COST APPLANATION TONOMETER (NEWTON) IN UGANDA
REFNo: HS3998ES

To evaluate the acceptability of the use of Newton to measure IOP in patients by different eye care workers.,To evaluate the acceptability of the use of Newton to measure IOP by patients,To evaluate agreement between IOPs from the Newton versus two other established tonometers (Goldmann applanation tonometer (GAT) and iCare).,To determine the specificity and sensitivity of Newton in measuring IOP versus Goldmann applanation tonometer (GAT) as the gold standard.,
 Uganda 2024-07-23 14:44:42 2027-07-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John ILUNGOLE Stephen
ID:
EVALUATION OF THE EFFECTIVENESS OF UMEME WUUYO CAMPAIGN AGAINST POWER THEFT IN UGANDA
REFNo: SIR339ES

ii. To find out whether the public received the messages used in the Wuuyo communications campaign against power theft. ,i. To assess the effectiveness of campaign messages used in the Wuuyo campaign against power theft. ,To assess whether the Umeme Wuuyo Communications Campaign against power theft in Uganda was successful.,
 Uganda 2024-07-22 17:18:00 2027-07-22 Engineering and Technology Non-Clinical Trial Degree Award
LAKER SCOVIA
ID: UNCST-2023-R006650
 Antioxidants and Nutritional Potential of Enriched Millet Based Composite Flour Using Spirulina (Arthrospira platensis)
REFNo: A432ES

The objectives will be to; 1. determine the proximate composition (moisture content, ash content, fiber content and protein content) in non-germinated and germinated millet flours of eight selected local millet varieties (Ekwangapel, Ekaama, Emoro moru, Ayuku manyige, Odyera, Min bel, Luk caa and Adyang adyang). 2. determine the concentration of minerals (zinc, calcium, magnesium and iron) in non-germinated and germinated millet flours of eight selected local millet varieties (Ekwangapel, Ekaama, Emoro moru, Ayuku manyige, Odyera, Min bel, Luk caa and Adyang adyang). 3. determine the concentration of anti-nutritional factors (oxalates, tannins and Phytates) in non-germinated and germinated millet flours of eight selected local millet varieties (Ekwangapel, Ekaama, Emoro moru, Ayuku manyige, Odyera, Min bel, Luk caa and Adyang adyang). 4. determine the antioxidant potential (Beta carotene) in spirulina powder and germinated millet composite flours of three selected local millet superiors. 5. determine the consumer acceptability of the spirulina millet-based product (porridge) of three selected local millet superiors.
Uganda 2024-07-22 17:15:54 2027-07-22 Agricultural Sciences Non-Clinical Trial Degree Award
Alex Ario Riolexus
ID:
Surveillance System Performance, Timeliness Metrics and Framework of Response to Anthrax Outbreaks in Uganda: Implications for Programming and Control of Zoonotic Diseases Epidemics
REFNo: HS4277ES

4- Develop a One Health Model response framework for zoonotic disease outbreaks,3- Examine timeliness of response to anthrax outbreaks in Uganda for the period 2014 to 2023 and compare with 7:1:7 as a metric for strengthening response and improving systems in real time,2- Assess the human and animal anthrax surveillance system functions and attributes in Uganda,1- Identify gaps in epidemiological investigations of anthrax outbreaks in Africa for the period 2014 to 2023,The general objective of this study is to assess performance of the surveillance system and timeliness of response to anthrax outbreaks in Uganda, 2014 - 2023.,
 Uganda 2024-07-22 17:13:33 2027-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Swaibu Zziwa
ID: UNCST-2022-R011017
 MOBILITY RECOVERY AFTER A LOWER LIMB BONE FRACTURE; EFFECTS OF A MULTI- COMPONENT HOME BASED REHABILITATION PROGRAM ON MOBILITY RECOVERY IN GREATER KAMPALA, UGANDA
REFNo: HS4641ES

1.To describe the type of care received by patients with lower limb fractures after hospital discharge in Greater Kampala, Uganda. 2.To determine mobility recovery and predictors of mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda. 3.To develop and validate a multi component home based rehabilitation program to improve mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda. 4.To evaluate the effect of a multi component home based rehabilitation program on mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda.
Uganda 2024-07-22 17:09:51 2027-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
AKANKWASA JOHNSON
ID: UNCST-2023-R006429
 Factors Associated with Home Based Care Services in the Control of Covid - 19 Infection in Sheema Municipality, Sheema District
REFNo: SS2402ES

3.To establish the existing, new policies and practices about home based care agencies that addressed challenges resulting from the COVID-19 pandemic in the 3 years of the peak pandemic.,2. To establish the social demographic, social economic and environmental factors that affected home based care services (HBC) in all the COVID-19 suspects during 2019 pandemic.,1. To investigate the level of utilization of Home Based Care services (HBC) in percentages among the isolated COVID-19 suspects in the control of COVID-19 infection in Sheema Municipality from 2020 to 2023.,To establish factors associated with Home Based Care Services (HBC) during COVID -19 infection in Sheema Municipality, Sheema District.,
 Uganda 2024-07-22 17:06:47 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Mathias Seviiri
ID:
Genetics of Glaucoma in High-risk Diverse Populations (GoGLAD) Study
REFNo: HS3427ES

General objective
To apply and critically evaluate the efficacy of genetic-based risk prediction models for glaucoma in an understudied, high-risk, genetically diverse continental African population in Uganda.

Specific objectives
1. To test the feasibility of collecting quality pilot clinical data on glaucoma related phenotypes, genetic data from a unique high-risk diverse population in Uganda.
2. To assess cross-ancestry genetic-based prediction of glaucoma risk in major diverse ancestry populations.
2A- To apply our current European-based genetic prediction model of glaucoma to a high-risk population of African ancestry from Uganda.
2B - To develop, and calibrate an African ancestry genetic prediction model of glaucoma and implement it in populations of European and African ancestries.
2C- To develop, model and calibrate a cross-ancestry genetic prediction model and apply it in populations of European and African ancestries.
3. To apply artificial intelligence to eye images to characterise ancestral differences in glaucoma risk and evaluate estimation of disease risk and progression.
4. To assess participants’ attitude towards genetic testing for glaucoma.

 Uganda 2024-07-22 17:03:10 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nura Izath
ID: UNCST-2022-R009201
 Autothermo-a wearable continuous temperature measuring bracelet with a central display screen.
REFNo: HS3034ES

To assess the performance of Autothermo- a wearable continuous temperature measuring bracelet and a central display screen in comparison to the standard thermometer.,To assess the feasibility and acceptability of Autothermo among health workers and parents/caregivers of admitted neonates at Mbarara Regional Referral Hospital(MRRH).,
 Uganda 2024-07-22 16:57:35 2027-07-22 Medical and Health Sciences Clinical Trial Non-degree Award
David Aderu
ID: UNCST-2023-R008280
 Mainz II Pouch: A viable option for the incurable fistula in Uganda
REFNo: HS3247ES

3. To assess the quality of life of recipients of the Mainz II pouch in clients with fistula deemed incurable at SRRH from 2009 to 2018.,2. To describe sonographic characteristics of the upper urinary tract in recipients of the Mainz II pouch procedure at SRRH from 2009 to 2018.,1. To determine the biochemical profile of patients with fistula deemed incurable who have undergone Mainz II pouch procedure at SRRH from 2009 to 2018.,To evaluate the viability of the Mainz II urinary diversion for women with Fistula deemed incurable in Uganda. ,
 Uganda 2024-07-22 16:53:11 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Aisha Nanyiti
ID: UNCST-2021-R013489
 Electric cooking in the energy transition: how much subsidization is needed?
REFNo: SS2896ES

To assess the willingness to pay for modern electronic cooking technology within the grid connected urban and peri-urban areas. To assess the effect of benchmark goods on the willingness to pay for modern electronic cooking technology. To assess the impact of information provision towards the demand for modern electronic cooking technology within the grid connected urban and peri-urban areas.
Uganda 2024-07-22 16:52:07 2027-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
 Identifying the Essential Elements of Case Managers and Peer Support Groups for Prophylaxis Adherence in Rheumatic Heart Disease” (CAMPS Plus)
REFNo: HS4346ES

Objective 1: Determine the difference in 1-year SAP adherence rates of children newly diagnosed with RHD in Uganda receiving one of two support strategies: case manager only (CM) and case manager plus peer support group (CM + PG).

Objective 2: Explore implementation determinants among case managers, participants, and participant families to inform deployment of program at scale.
 Uganda 2024-07-22 16:49:34 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Kiguba
ID: UNCST-2019-R000844
 Understanding adverse drug reactions to dolutegravir and isoniazid in people living with HIV in Uganda: incidence, risk factors, management and patient reporting
REFNo: HS3364ES

To determine the incidence, characteristics and risk factors of ADRs to DTG/ IPT in PLHIV in Uganda,To identify barriers and facilitators of using the app to report ADRs by PLHIV in Uganda,To determine the rate of ADR-reporting by PLHIV at selected ART-sites in Uganda,To implement the Med Safety app to promote ADR-reporting by PLHIV in Uganda,To identify genetic polymorphisms associated with DTG-induced weight gain and hyperglycaemia, and isoniazid-related hepatotoxicity, using the GWAS approach among PLHIV in Uganda,To investigate the prevention, monitoring, management of ADRs to DTG/ IPT in PLHIV in Uganda,
 Uganda 2024-07-22 16:37:17 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elisa  Macchi
ID: UNCST-2023-R004097
 Pressure to Hire, Technology Adoption, and Productivity: Experimental Evidence from Uganda
REFNo: SS2013ES

1. The project aims at contributing to several strands of the literature. First, an emerging literature
hasshown how social- and self-image concerns affect the labor market through changesin the labor
supply

2. Our evidence suggests that the reputational concerns associated to hiring and technology
adoption decisions are induced by resource-sharing practices with kin and neighbors.

3. Finally, our work links to the literature on cross-country differences in productivity. Lewis et al.
(1954) observed that developing economies have a large “traditional sector” where marginal
productivity is low and where workers may be compensated above their marginal product through
informal arrangements (see Gollin (2014) for a recent discussion). When wages do not equal
marginal product, workers may be employed in relatively less-productive tasks, resulting in
misallocations. Gollinetal
 Italy 2024-07-22 16:32:03 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Patience Atuhaire
ID: UNCST-2023-R007423
 TORCHES (TOXOPLASMOSIS, RUBELLA, CYTOMEGALOVIRUS, HERPES AND OTHER AGENTS LIKE SYPHILIS) and relation to Preterm Delivery and Low birth weight among pregnant women living with HIV and their babies in the IMPAACT 1077BF trial
REFNo: HS4352ES

Assess/evaluate the associations between select peripartum infections with risk of PTD and LBW, across the ART groups reported in PROMISE,assess the prevalence of select peripartum co-infections (TORCH infections) among PROMISE 1077BF women living with HIV and their HEU babies at the MU-JHU CRS in Kampala Uganda using stored plasma specimens obtained at delivery,
 Uganda 2024-07-22 15:03:09 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Douglas Bulafu
ID: UNCST-2021-R011774
 From COVID-19 to Ebola: How did lessons on Maintaining Essential Health Services during the COVID-19 Pandemic inform the Ebola response in Uganda?
REFNo: HS4422ES

5. To compare disruption to essential health services due to COVID-19 and Ebola in Mubende and Kassanda districts of Uganda.,4. To estimate the effect (disruption) of COVID-19 and Ebola in Mubende and Kassanda districts of Uganda.,3. To explore the challenges faced during implementation of public health and social measures during the Ebola epidemic in Uganda.,2. To document how lessons from previous pandemics informed the application of public health and social measures during the Ebola epidemic in Uganda.,1. To document how lessons from previous epidemics informed the health system adaptations to ensure the continuity of essential health services during the Ebola epidemic in Uganda.,To compare disruption to essential health services during COVID-19 and the 2022 Ebola outbreak and document how lessons from the COVID-19 pandemic informed the Ebola response in Uganda to inform how to prevent and respond to future epidemics.,
 Uganda 2024-07-22 15:02:01 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abbey Kato
ID:
Child art: a meaning-making mechanism for children about their gender[ed] experiences and perceptions
REFNo: SS2341ES

To interrogate children’s visual art expression as a model for gender sensitization.,To examine the gender[ed] narratives that emerge from the child art experiences and perceptions expressed in the child art.,To explore children’s experiences and perceptions of their day to day life expressed through child art.,The main objective of the study is to explore how child art can be used as a meaning-making mechanism by children to express their everyday life gender[ed] experiences and perceptions.,
 Uganda 2024-07-22 14:57:37 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Daniel Mwandah Chans
ID: UNCST-2022-R008880
 Antimicrobial Stewardship in Critical Care: Prevention of the Transmission of Multi-Drug Resistant Superbugs in the Intensive Care Unit of Mbarara Regional Referral Hospital (AMSICU)
REFNo: HS4682ES

6. Develop an IPC protocol for the ICU.,5. Provide training on the role of pharmacokinetics (PK) and pharmacodynamics (PD) in managing critically ill patients in order to optimize antimicrobial therapy.,4. Develop a treatment algorithm for the selection of the initial antibiotic therapy and antimicrobial therapy de-escalation in the ICU.,3. Establish the use of biomarkers for rapid identification of ICU patients with bacterial infections.,2. Document the baseline antimicrobial resistance patterns for the ICU.,1. Establish a structured antibiotic stewardship program in the ICU at MRRH involving intensivists, microbiologists, nurses, specialists, clinicians, clinical pharmacists, hospital administrators and support staff.,The overall aim of the project is to prevent transmission of multi-drug resistant (MDR) superbugs in the intensive care unit (ICU) at Mbarara Regional Referral Hospital (MRRH) through building capacity of clinicians for antimicrobial stewardship (AMS) and infection prevention and control (IPC) for improved patient outcomes,
 Uganda 2024-07-22 14:52:09 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
KYARIKUNDA MONICA
ID: UNCST-2023-R005922
 Community Based Tourism Enterprises’ appraisal and community conservation outcomes amidst changing demographics around Bwindi Impenetrable National Park.
REFNo: SS2416ES

To determine strategic initiatives for enhancing CBTEs’ performance for better community conservation outcomes in the digital era amidst changing demographics,To explore how the changing demographics have affected the implementation and performance of CBTEs around Bwindi Impenetrable National Park,To establish the CBTEs’ performance and community attitudes’ trend towards conservation of BINP,To characterize and map the spatial and temporal distribution of community Based Tourism Enterprises around Bwindi Impenetrable National Park. ,To determine barriers and facilitators of CBTEs’ performance and resultant community conservation outcomes of Bwindi Impenetrable National Park amidst changing demographics,
 Uganda 2024-07-22 14:46:50 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
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