Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ODOI PASKARI
ID:
Experiences of School Children Affected by Bilharzia in Hoima District and Adherence to Treatment
REFNo: SS1463ES


General Objective
To examine experiences of illness by school children affected by bilharzia and their adherence to MDA treatment in Hoima district, Uganda.

Specific Objectives
a) To examine the socio-cultural factors that influence adherence to MDA among schoolchildren;
b) To assess the interaction between school children and the providers of treatment during MDA;
c) To document the daily lived experiences of school children that shape adherence to MDA.

Uganda 2022-10-13 13:13:41 2025-10-13 Social Science and Humanities Non-Clinical Trial Degree Award
Yvonne Mugerwa Kidza Kitego
ID:
Heat-stable Carbetocin for Postpartum Hemorrhage prevention and Tranexamic Acid for PPH treatment in Basic Emergency Obstetric and Newborn Care facilities: Protocol for a pilot study in humanitarian settings in Uganda
REFNo: HS2456ES

The specific objectives of the study are to 1. To explore the feasibility, acceptability, and scalability of introduction of HSC and TXA in PPH prevention and management (as per WHO PPH guidelines) in BEMONC facilities in Humanitarian settings in Uganda. 2. To identify facilitators and barriers to successful introduction of HSC and TXA for PPH prevention and management (as per WHO PPH guidelines) in BeMONC facilities in Humanitarian settings In Uganda. (Including facilitators and barriers to introduction of and adherence to the WHO PPH guidelines in general). 3. To describe the effect (on quality of maternal and newborn health care) of introduction of a package of interventions that includes a) refresher training on PPH prevention and management (as per WHO and MOH guidelines) and b) introduction of HSC and TXA for PPH prevention and management of PPH in BEMONC facilities in Humanitarian settings in Uganda. ,
Uganda 2022-10-13 13:10:55 2025-10-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lynn Atuyambe Atuyambe
ID: UNCST-2021-R012602
Integrating rehabilitation into primary health care and mapping of rehabilitation services in Uganda
REFNo: HS2414ES

General objective
In this study, we will investigate the feasibility of integrating rehabilitation into primary health care in Uganda. We will also map current rehabilitation services in Uganda and explore their level of integration with health systems for providing continuous, comprehensive and coordinated rehabilitation services. This will be pivotal in panning for and improving rehabilitation services in Uganda.

Specific objectives
1. To develop consensus among key health and rehabilitation sector stakeholders on integrating physical rehabilitation services into primary health care (PHC) in Uganda.
2. To determine the feasibility and capacity for PHC services in Uganda to undertake physical rehabilitation services as additional roles and tasks.
3. To determine the geographical distribution and coverage of physical rehabilitation services in the selected districts, and their level of integration with health systems for providing continuous, comprehensive and coordinated rehabilitation services.

Uganda 2022-10-13 13:08:48 2025-10-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Racheal Nangobi
ID:
INSTITUTIONAL AND MANAGEMENT FACTORS INFLUENCING SUSTAINABILITY OF FARMER ORGANIZATIONS IN UGANDA
REFNo: SS1120ES

1. To characterize farmer organizational business models and agricultural institutional frameworks in Uganda.
2. To assess factors influencing organization structures of farmer organizations in Uganda.
3. To assess factors influencing leadership styles being used by farmer organizations in Uganda.
4. To assess the influence of organization structure, leadership, business model and institutional frameworks on sustainability of farmer organizations in Uganda.

Uganda 2022-10-12 11:30:43 2025-10-12 Social Science and Humanities Non-Clinical Trial Degree Award
Fred Maniragaba
ID:
DETERMINANTS OF OLDER PERSONS’ ACCESS TO SAFE WATER AND HEALTH SERVICES IN THE INFORMAL SETTLEMENTS OF KAMPALA, UGANDA
REFNo: HS2487ES

1. Examine the demographic and socio-economic determinants of access to health services by older persons in informal settlements in Kampala, Uganda;

2. Explore the facilitators and barriers of access to clean water by older persons in informal settlements in Kampala, Uganda.

Uganda 2022-10-11 12:40:32 2025-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
George Lyimo Wilfred
ID:
PREVALENCE, ASSOCIATED FACTORS AND COMPLICATIONS OF RECURRENT TONSILLITIS AMONG CHILDREN AGED 6- 13 YEARS IN MBARARA REGIONAL REFERRAL HOSPITAL.
REFNo: HS2450ES

To explore the complications of recurrent tonsillitis in children aged 6- 13 years with recurrent tonsillitis in MRRH.,To explore factors associated with recurrent tonsillitis among children aged 6- 13 years in MRRH.,To determine the prevalence of recurrent tonsillitis among children aged 6-13 years in MRRH.,To determine the prevalence, associated factors and complications of recurrent tonsillitis among children aged 6- 13 years in MRRH,
Tanzania 2022-10-11 12:32:45 2025-10-11 Medical and Health Sciences Non-Clinical Trial Degree Award
James Muiga Muriithi
ID:
Green Economy Baseline Survey: A Survey on Social Acceptability of Climate Change Reforms in Uganda
REFNo: NS427ES

To study the social acceptability of critical green economy reforms in Uganda.
Kenya 2022-10-11 12:30:30 2025-10-11 Natural Sciences Non-Clinical Trial Non-degree Award
Harriet Mayanja-Kizza
ID: UNCST-2021-R013074
A Survey Assessing Male Reproduction After Treatment with HRZE/HR
REFNo: HS2423ES

To evaluate the paternity status in male participants who have received a HRZE/HR regimen in one of the following TB Alliance clinical trials: STAND or SimpliciTB.
Uganda 2022-10-11 12:25:30 2025-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gracious Ahumuza Martha
ID:
The “Diabetes CarePak” Project: Enabling Increased Access to Safe Administration of Insulin and Self-Care for People Living with Diabetes in Uganda
REFNo: HS2418ES

• Objective 1: To map the health care journey of PLWD and identify the access barriers for commodities needed for safe administration of insulin and self-management of diabetes.
• Objective 2: To determine the learning needs of PLWD and health care workers (HCWs) to inform development of educational material.
• Objective 3: To develop a CarePak prototype, which includes the type and quantity of commodities, as well as the educational materials, to be included in the CarePak.
• Objective 4: To assess the CarePak prototype for desirability, acceptability, usability, feasibility, and impact on clinical outcomes over a three-month period.
Uganda 2022-10-11 12:23:30 2025-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Denis Bbosa
ID: UNCST-2021-R012847
RECYCLING OF PLASTIC WASTE INTO ECO-FRIENDLY INTERLOCKING BLOCKS TO ADDRESS THE CHALLENGES OF HOUSES FOR THE POOR PEOPLE AND THE CONSTRUCTION OF UPE/USE SCHOOL CLASSROOMS.
REFNo: SIR148ES

1) To produce Lego-like interlocking blocks as an alternative construction material. 2) To investigate the properties of products produced in terms of compression, hardness/tensile, and water absorption. . 3) To investigate the effect of adding ash to the proposed interlocking blocks. The hypothesis is to find out if the addition of ash to the mixture improves the mechanical properties of the interlocking block. 4) To compare the properties of similar material(s) already on the market with the produced product(s).
Uganda 2022-10-11 12:20:58 2025-10-11 Engineering and Technology Non-Clinical Trial Non-degree Award
Jimmy Wanzala Nabende
ID:
DESIGN AND SIMULATION OF AN INTELLIGENT MEDICAL VENTILATOR SYSTEM FOR PATIENT-VENTILATOR SYNCHRONY AND LUNG PROTECTION
REFNo: HS2492ES

Design and simulate an intelligent system for patient ventilator synchrony and lung protection using real-time medical imaging and fuzzy expert system,Build a feed-in ultrasound imaging model to detect severity of acute respiratory distress syndrome using convolutional neural network,Build a patient-response based model for ventilator adjustments in acute respiratory distress syndrome patients using fuzzy neural network,Design and simulate a physician based fuzzy logic system for ventilator adjustments in acute respiratory distress syndrome patients to ensure lung protection,
Uganda 2022-10-07 13:28:32 2025-10-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Ponsiano Ocama
ID: UNCST-2019-R000440
Chronic infection and hepatocellular cancer: Impact of Schistosoma mansoni, HIV, HBV, and their treatment in sub-Saharan Africa
REFNo: HS2361ES

1. To characterize the impact of medical treatment of Sm on chronic hepatitis B in SSA.
2. To correlate the dynamics of HBV infection during Sm treatment with changes in inflammatory cytokines and HBV-specific immunological responses
3. To compare expression of c-JUN and other oncogenes and HCC-related activation pathways in hepatocytes and periportal inflammatory tissue in HBV patients pre- and post-Sm treatment.

Uganda 2022-10-07 13:20:56 2025-10-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Odongo Nespaul
ID: UNCST-2021-R014002
A Survey on Migration, Intergroup Relations, and Inclusivity”
REFNo: SS1353ES

The objective of this research is, in short, to use a survey
of 3000 adult Ugandans to understand their attitudes on matters of intergroup relations and
identify whether residential location and migration histories are important determinants of the
extent to which individuals are inclusive of those who do not share their own identities
Uganda 2022-10-07 13:17:11 2025-10-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Florence  Nansumbi
ID:
Functional Indicators to assess freshwater ecosystem integrity: Biogeochemical dynamics of carbon, nitrogen and phosphorous cycling and stream metabolism
REFNo: NS402ES

The aim of this study is to evaluate the ecological status of sections of a Ugandan river with different levels of human impact using stream metabolism as a functional indicator.
It intends to investigate the following objectives:
i. To examine the role of catchment land-use and seasons in determining river water quality nutrient and dissolved organic carbon concentrations and the effects it has on water quality
ii. To investigate how stream metabolism responds to nutrient and organic matter loading along land use and seasonal gradients
iii. To assess the environmental parameters controlling stream metabolism in tropical streams and their seasonal variation along land-use gradients
iv. To investigate the relationship between stream processes and biological components of the river and their sensitivity to nutrient and organic matter pollution.

Uganda 2022-10-06 9:54:38 2025-10-06 Natural Sciences Non-Clinical Trial Degree Award
Joshua Kiptoo
ID:
SAFETY AND EFFECTIVENESS OF A SELECTED HERBAL MEDICINAL PRODUCT AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS IN MBARARA CITY, SOUTHWESTERN UGANDA.
REFNo: HS2440ES

To determine the cost-effectiveness of the selected HMP among patients with T2DM in Mbarara City.,To determine the safety of the selected HMP among patients with T2DM in Mbarara City.,To determine the effectiveness of a selected HMP among patients with T2DM in Mbarara City.,To identify the commonly used HMPs among T2DM patients in Mbarara City.,To evaluate the safety and effectiveness of a selected HMP among patients with T2DM in Mbarara City.,
Uganda 2022-10-06 9:53:17 2025-10-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anatoli Muleterwa
ID:
THE ROLE OF POLICING IN COUNTERING URBAN TERRORISM IN KAMPALA METROPOLITAN
REFNo: SS1436ES

General objective
The general objective of the study is to examine the influence of policing in countering urban terrorism in Kampala Metropolitan in order to reduce the incidents of terrorism through improving the working relationship between police and the community.
1.3.2 Specific Objectives
The specific objectives are;
1. To examine the role of police in countering urban terrorism in Kampala Metropolitan
2. To assess the effectiveness of police in identifying and countering urban terrorism in Kampala Metropolitan
3. To explore the role of community in countering urban terrorism in Kampala Metropolitan
4. To examine the relationship between police and community in countering terrorism in Kampala Metropolitan

Uganda 2022-10-05 15:07:23 2025-10-05 Social Science and Humanities Non-Clinical Trial Degree Award
Winnie  Muyindike R
ID: UNCST-2021-R013558
HIV-1 subtype-specific drug resistance in patients failing dolutegravir-based first-line, second-line or third-line regimens: multiregional study (DTG resist study)”
REFNo: HS2435ES

Main Objective 1.To determine the patterns and spectrum of InSTI DRMs in adults and adolescents with virologic failure on DTG-based ART by ART regimen and HIV-1 subtype. 2. To identify risk factors for virologic failure, InSTI DRMs, and InSTI drug resistance in adolescents and adults on DTG-based ART, including drug, host and health system factors. Specific Objectives 1a) To identify the prevalence of InSTI DRMs at the time of virologic failure. 1b) To compare the prevalence of InSTI DRMs at the time of virologic failure between HIV-1 subtypes and treatment contexts. 2a) To identify risk factors for Virologic Failure 2b) To identify risk factors for Drug Resistance Mutations. 3. To investigate correlations between novel resistance genotypes and phenotypic DTG resistance across HIV-1 subtypes.
Uganda 2022-10-05 15:04:09 2025-10-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jefferson  Mtongolo Mwaisaka
ID: UNCST-2022-R010784
An impact evaluation study of the Delivering Resilient Enterprises and Market Systems (DREAMS) project targeting refugees and host communities in Bidi Bidi and Rhino Camps, West Nile Uganda
REFNo: SS1445ES

To determine the cost-effectiveness of DREAMS compared to the status quo,To assess if there's any suggestive evidence that outcomes are substantially different for households that participate in both graduation and MSD programs vs households that only participate in graduation programs,To determine the impact of DREAMS on livelihoods, social cohesion, and perceived wellbeing among vulnerable households in host communities in Uganda’s West Nile refugee settlements,To determine the impact of DREAMS on livelihoods, social cohesion, and perceived wellbeing among vulnerable households in a refugee camp in Uganda’s West Nile refugee settlements,To determine the impact of DREAMS (poverty graduation + indirect MSD + direct market support) on livelihoods, social cohesion, and perceived wellbeing of vulnerable refugee and host community households in Uganda’s West Nile refugee settlements,
Kenya 2022-10-05 12:26:04 2025-10-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Samson Omongot
ID:
Validation of air pollution particulate matter measurements and characterization of the source apportionment using chemical speciation in urban Kampala.
REFNo: NS416ES

ii) To determine sources of pollutants using filter sampler Gravimetric Method in 12 months at Makindye & Kawempe divisions of Kampala district.,Specific objectives for Aim 2 i) To determine chemical composition of pollutants using filter sampler Gravimetric method in 12 months at Makindye & kawempe divisions of Kampala district,Aim 2 General Objective To determine the pollutants’ components in particulate matter (PM) and establish their specific sources using filter sampler gravimetric method in computer-based model Positive Matrix Factorization (PMF),iii) To assess the correlation of PM2.5 measurements between AirQo twin plan tower Monitor and filter sampler Gravimetric method,ii) To determine the correlation of the PM2.5 measurements between the filter sampler Gravimetric method, and the internationally standardized Kampala BAM ,Specific Objectives for Aim 1 i) To determine the correlation of PM2.5 measurements between AirQo twin plan tower monitors and the internationally standardized Kampala BAM ,Aim 1 General Objective To examine the correlation of ambient air pollution PM2.5 measurements between AirQo twin Plan tower Monitor (TPTM), filter sampler Gravimetric method and US Embassy Beta Attenuation Monitor (BAM).,
Uganda 2022-10-05 12:24:41 2025-10-05 Natural Sciences Non-Clinical Trial Non-degree Award
Wilfred Arubaku
ID:
Role of Physiotherapy in Ugandan Neurosurgical Transitional Care
REFNo: HS2369ES

3. To examine the knowledge, attitudes and beliefs of medical providers, rehabilitation providers, patients, and caregivers as to the inclusion of rehabilitation services in discharge practice.,2. To describe the experiences of discharge practice from the perspectives of medical providers, rehabilitation providers, patients, and caregivers.,1. To describe the process steps that are happening during discharge practice for medical providers, rehabilitation providers, patients, and caregivers.,This study aims to examine and understand the involvement of current rehabilitation professionals in discharge practices TBI and SCI patients in acute hospital settings. Results from this study will inform the development of care transition interventions that increase patient access and utilization of rehabilitation services to improve quality of life.,
Uganda 2022-10-05 12:23:17 2025-10-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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