Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
RACHAEL KULWENZA
ID:
EXPLORING THE TEACHING OF READING IN LOWER PRIMARY CLASSES IN KOCHEKA SUBCOUNTY, UGANDA. A CASE OF ONE GOVERNMENT PRIMARY SCHOOL.
REFNo: SS987ES

•To find out what teaching and learning approaches do teachers use to teach reading in the lower primary level. •To investigate how do the approaches that teachers use in teaching reading in lower primary levels impact the development of the reading competences of the children?
•To find out what opportunities and challenges exist when teaching reading to learners in the lower primary level?

Uganda 2021-11-15 2024-11-15 Social Science and Humanities Non-Clinical Trial Degree Award
RICHARD EDEMA BAZIL
ID:
Investigating how teachers use mother tongue as a medium of instruction for lower primary mathematics
REFNo: SS1013ES

The objectives of the study are to establish: -
1. How the teachers are providing for the use of mother tongue as a medium of instruction during preparation for teaching and learning lower primary mathematics?
2. How the teachers are using mother tongue as a medium of instruction during teaching and learning processes of mathematics in P1 to P3?
3. The opportunities presented by the use of mother tongue in the teaching and learning of mathematics in P1 to P3?
4. The challenges the teachers face in the use of Mother tongue as a medium of instruction for mathematics in lower primary classless?

Uganda 2021-11-15 2024-11-15 Social Science and Humanities Non-Clinical Trial Degree Award
Arthur Bagonza
ID:
EFFECT OF COVID-19 ON PAEDIATRIC FEVER TREATMENT AMONG REGISTERED PRIVATE DRUG SELLERS IN EAST-CENTRAL UGANDA
REFNo: HS1729ES

1. To determine the effect of lock-down due to COVID-19 on treatment of children less than five years presenting with malaria,diarrhoea and pneumonia symptoms at registered private drug shops in Luuka district, East Central Uganda.

2. To explore perceptions of drug sellers and key stakeholders regarding treatment of children less than five years presenting with malaria,diarrhoea and pneumonia symptoms at registered private drug shops in Luuka district,East Central Uganda.

Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fatumo  Segun Adeyemi
ID:
Causal Relationship between Cardiometabolic traits and Chronic Kidney Disease in African Population.
REFNo: HS1730ES

1. To Identify genetic determinants of kidney function in continental Africa"
2. To investigate the predictive utility of Polygenic Risk Scores for Chronic Kidney disease in Africans.
3. To assess the causal effect of kidney function on cardiometabolic diseases using Mendelian Randomisation Approach.

UK 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Geoffrey Beyihayo Akiiki
ID:
Native Chicken Project
REFNo: A154ES

To establish genetic markers associated with economic traits among indigenous chicken eco-types,To establish genetic and phenotypic parameter estimates for economic traits among indigenous chicken eco-types,To assess the genetic diversity of indigenous chickens eco-types based on mitochondrial DNA (mtDNA),To characterize indigenous chicken based on qualitative and quantitative phenotypic traits ,To characterize and identify genetic markers of egg and growth traits for selection of highly productive indigenous multipurpose chickens ,
Uganda 2021-11-15 2024-11-15 Agricultural Sciences Non-Clinical Trial Degree Award
David Guwatudde
ID: UNCST-2021-R008522
The Uganda Non-Communicable Diseases (NCD) Risk Factor Mobile Phone Survey - 2021
REFNo: HS1738ES

1.Evaluate the efficacy (as measured by the response rate), of conducting a mobile phone survey to collect data on the common NCD risk factors

2.Collect data on specific NCD disease conditions, and the self-reported NCD risk factors to support monitoring and evaluation of programs and policies in Uganda.

3.Generate comparable data from mobile phone surveys within Uganda over time.

4.Provide data to the Ministry of Health and other relevant ministries, and make recommendations on developing, improving, and enhancing prevention and response strategies to address NCDs and NCD associated disabilities in Uganda.
Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allan Kalyesubula Edward
ID: UNCST-2021-R012991
The prevalence of oral diseases and their associated factors in children and adolescents attending the diabetes clinic at Mulago
REFNo: HS1799ES

1. To determine the prevalence of dental caries among children and adolescents attending the diabetes clinic at Mulago.
2. To determine the prevalence of periodontal diseases among children and adolescents attending the diabetes clinic at Mulago.
3. To determine the associated risk factors for dental caries among children and adolescents attending the diabetes clinic at Mulago.
4. To determine the associated risk factors for periodontal diseases among children and adolescents attending the diabetes clinic at Mulago
Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
BREATHER Plus: A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir- based triple ART in virologically suppressed HIV-infected adolescents aged 12 to 19 years of age in sub-Saharan Africa, Version 2.0, Dated 18-Mar-2020; ISRCTN #: 85058577
REFNo: HS1822ES

Major Objective: A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir-based triple ART in virologically suppressed HIV-infected adolescents aged 12 to 19 years of age in sub- Saharan Africa
Specific Objectives
To evaluate an innovative and contemporary ART strategy in HIV-infected adolescents to provide choice for young people facing life-long treatment. Output from this RCT will provide evidence on efficacy, safety and acceptability of a novel treatment approach in HIV-infected adolescents in sub-Saharan Africa
To evaluate the virological efficacy, safety, acceptability and Quality of Life of DTG-based Short-cycle Therapy with weekends off compared with Continuous Therapy with a DTG- based ART regimen
To optimize treatment for HIV-infected adolescents in sub-Saharan Africa

Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Clinical Trial Non-degree Award
Mvuyo Sikhondze Maqhawe
ID:
DIABETIC FOOT ULCERS: SURGICAL CHARACTERISTICS, TREATMENT MODALITIES AND SHORT-TERM TREATMENT OUTCOMES AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1857ES

General Objective
To describe the surgical characteristics, treatment modalities and short-term treatment outcomes of diabetic foot ulcers at Mbarara Regional Referral Hospital.

Specific Objectives
1. To describe the surgical characteristics of diabetic foot ulcers observed at Mbarara Regional Referral Hospital.
2. To describe the treatment modalities of diabetic foot ulcers at Mbarara Regional Referral Hospital.
3. To document the short-term treatment outcomes of patients with diabetic foot ulcers at Mbarara Regional Referral Hospital.
Eswatini 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Sabine, Willemina, Johanna Luning
ID:
Gold Matters: Transformations to Sustainability in Artisanal and Small Scale Gold Mining in Uganda
REFNo: SS716ES

1. To consider whether a transformative approach toward sustainability can arise in Artisanal and Small Scale Gold Mining (ASGM).
2. To explore new notions of sustainability and transformations.
3. To contribute to a better understanding of the dynamic, heterogeneous reality of ASGM.
Netherlands 2021-11-11 2024-11-11 Social Science and Humanities Degree Award
Jessica Perkins M
ID: UNCST-2021-R013564
Perceptions of Social Norms and Personal Propensity to Engage in HIV Testing: A Mixed Methods Study and Intervention in Rural Uganda
REFNo: SS812ES

We propose a study to assess norms and perceptions about HIV prevention and related topics. This includes assessing village norms (i.e., the behaviours or attitudes of more than 50% of the adult population), perceived norms, how people form their perceptions, which social reference groups are the most meaningful, and the difference between actual norms and individuals’ perceptions of what most others do or believe. We will also examine whether perceptions are associated with personal behaviours and attitudes. Project 1 Aim: To engage in secondary analysis of quantitative data about perceived social norms and actual population norms around HIV prevention behaviours and related topics across different social reference groups. Aim 1: We will assess the prevalence of perceived and actual behavioural norms. We will do this both at the village-level and across various sociodemographic and health indicators. We will consider a behaviour the village norm if it is reported by more than 50% of adults. Aim 2: Because the parent study includes nearly all adults living in Nyakabare Parish, we can compare the actual village norm (assessed in Aim 1) to perceptions of the village norm. The parent study asked participants about their perceptions of what most other adults in the village do or think. Aim 3: Using the self-reported behaviours, attitudes, and norm perceptions, we will test whether individuals’ perceptions of what is normative is related to their personal attitudes and behaviours. Project 2 Aim: To use qualitative research methods to understand the nuances of HopeNet participants’ perceptions about local norms and design valid survey questions that elicit perceived social norms about HIV testing within different reference groups. Aim 1: Through in-depth interviews, scenarios related to HIV prevention attitudes and behaviours and perceived norms about salient social reference groups will be discussed. Aim 2: Based on results from Aim 1, survey questions using different ways of assessing norms will be developed to assess perceived social norms around HIV-related prevention behaviours and attitudes among different reference groups. Aim 3: Through cognitive interviews, the content validity of these survey questions to elicit perceptions of social norms about HIV-related attitudes and behaviours among specific social reference groups will improve.
USA 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
SIMON EWASU -
ID:
EXPLORING THE INFLUENCE OF SCHOOL LEADERSHIP ON STUDENTS’ ACADEMIC PERFORMANCE: A COMPARATIVE STUDY OF TWO PRIMARY SCHOOLS’ IN OMODOI SUB-COUNTY-UGANDA
REFNo: SS980ES

1. To explore how school leadership influences learners’ academic performance in schools’?
2. What school leaders do to improve on the students’ academic performance in schools
3. To find out the teachers’ and students’ perceptions on the school leadership on students’ academic performance.
4. To find out the strategies school leaders employ to support their own teams to improve on the learner’s academic performance?

Uganda 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
Modular Wireless Patient Monitoring System (MWPMS) Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS1687ES

At the FPRRH study site in Uganda, investigators will incorporate an assessment of the utility of a novel Modular Wireless Patient Monitoring System (MWPMS), supported by personalized data analytics, to provide a continuous, objective measure of physiological status in patients with sepsis. We aim to demonstrate correlation with manually collected vital signs. We also aim to identify specific features or combinations of features measured via MWPMS that predict 28-day mortality. This is a sub-study which will be incorporated in the main protocol observing sepsis patients hospitalized in Uganda
Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Owenda Omulo Charles
ID:
The socioeconomic impact of floriculture industry on the livelihoods of communities hosting flower farms in Uganda
REFNo: SS1004ES

Main Objective
The main aim of this study is to examine the socio-economic impact of flower farm projects on the livelihoods of their host communities.

Specific Objectives
Specifically, the study will have the following objectives and associated research questions;
To find out how the financial reward (wages) has contributed in changing the livelihood of flower farm workers from the time they joined the flower farm.

To examine the extent by which flower farms have contributed to the improvement of the basic infrastructure and producer goods needed to support people’s livelihoods in their host communities.
To find out how the farms are prepared to overcome the challenges of environmental degradation and human abuse (as witnessed in workers’ exposure to hazardous agrochemicals in other countries) in order to improve people’s livelihoods.

Kenya 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Christine Watera
ID:
Cyclical Acquired HIV Drug Resistance Surveillance: Focusing on Dolutegravir in Uganda
REFNo: HS1774ES

a) To estimate the prevalence of acquired drug resistance (ADR) among individuals receiving DTG for at least 12 months with VL non suppression, by age sub-groups
• Adolescents and Adults ≥ 15 years
• Children < 15 years old
b) To describe the patterns of ADR among individuals receiving DTG for at least 12 months with VL non suppression, by age sub-groups
c) To describe the prevalence and pattern of ADR among individuals receiving DTG with VL non-suppression by sub-population characteristics (e.g., sex, duration on antiretroviral therapy (ART), line of ART, pregnant and breast feeding, etc.):
d) To compare the proportion of individuals with HIVDR pre- and post-intensive adherence counselling (IAC)

Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Birungi Mwebaze
ID:
Decision Making Dynamics in the use of Female Sterilisation by Women Living with HIV in Uganda
REFNo: SS1044ES

To explore the personal factors that influence the agency to implement decisions regarding use of sterilisation by women living with HIV in Uganda, To describe the micro-level social contexts that influence the decisions of Women Living with HIV on the sue of female sterilisation by as a method of contraception, To assess the macro- level cultural contexts that influence the decisions of Women Living with HIV to use sterilisation.
Uganda 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Agata Staniewicz
ID: UNCST-2021-R012236
Interspecific competition for acoustic space in birds
REFNo: NS302ES

Determine whether and how various species of birds compete with each other and with other animals for acoustic space.
Poland 2021-11-11 2024-11-11 Natural Sciences Non-Clinical Trial Non-degree Award
Karlmax Rutaro
ID: UNCST-2021-R012720
Value chain hygiene practices and microbial contamination of street and market vended ready-to-eat grasshoppers, Ruspolia spp. in Uganda
REFNo: HS1869ES

The overall aim of the study is to document the value chain hygiene practices and microbial contamination of street-hawked and market-vended RTE grasshoppers, Ruspolia spp. in Uganda.

The specific objectives are:
i. To document the hygiene practices along the RTE grasshopper value chain, including the personnel involved, in Kampala City and Masaka Town in Uganda.
ii. To determine the level of microbial contamination in the RTE grasshoppers at different stages of the value chain in Kampala City and Masaka Town in Uganda.
iii. To establish the relationship between RTE grasshopper value chain hygiene practices and the microbial contamination.

Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allen Namagembe Sekitoleko
ID: UNCST-2019-R000214
Injecto Easyject contraceptive self-injection use in Uganda
REFNo: HS1851ES

1.To assess ease of use of the Easyject device, from the perspective of clients (self-administration) and providers (provider administration), relative to the Uniject
2.To identify challenging steps when learning to use the Easyject
3.To evaluate overall acceptability of Easyject injection device for clients, providers and stakeholders
Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane Namukobe
ID:
Bioactivity and chemical investigation of natural products composition from selected plants used in skin infections and protection.
REFNo: NS306ES


i. To determine the sun protection, antioxidant and antibacterial activities of extracts from selected plants used in skin infection and protection
ii. To determine the dermal and oral toxicity of extracts
iii. To isolate and elucidate the structures of bioactive compounds
iv. To determine the sun protection factor, antioxidant and antibacterial activities of isolated compounds
v. To prepare synthetic derivatives of some interesting isolated compounds

Uganda 2021-11-11 2024-11-11 Natural Sciences Non-Clinical Trial Non-degree Award
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