Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ronald Angupale Jimmy
ID:
Design, Development and Characterization of Drug Delivery Systems for Ugandan Antimalarial Plants - Artemisia annua, Vernonia amygdalina and Microglossa pyrifolia
REFNo: HS1886ES

4. To optimize the developed drug delivery system(s) with respect to the critical product quality attributes and assess their antimalarial efficacy and safety,3. To design and develop suitable herbal drug delivery systems (conventional and novel) for the plant extracts,2. To carry out preformulation studies (physicochemical properties) for the plant extracts,1. To determine in vivo antimalarial efficacy of selected combinations of A. annua, V. amygdalina and M. pyrifolia ,To design, develop and characterize drug delivery systems for selected Ugandan antimalarial plants – Artemisia annua, Vernonia amygdalina and Microglossa pyrifolia,
Uganda 2024-07-26 13:50:14 2027-07-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
Outcomes of paediatric inguinal hernia repair performed by surgeons versus medical officers
REFNo: HS4508ES

Calculate and compare costs and cost-effectiveness between the two groups. ,Compare patient related outcomes between the group that has been operated on by medical officers versus those who were operated by general surgeons. ,The general objective of the proposed study is to investigate the possibility of task sharing between general surgeons and medical officers in inguinal hernia repair in children in Uganda. ,
Sweden 2024-07-23 15:30:50 2027-07-23 Medical and Health Sciences Clinical Trial Degree Award
Immaculate  Atukunda
ID: UNCST-2021-R013573
EVALUATION OF A NEW LOW-COST APPLANATION TONOMETER (NEWTON) IN UGANDA
REFNo: HS3998ES

To evaluate the acceptability of the use of Newton to measure IOP in patients by different eye care workers.,To evaluate the acceptability of the use of Newton to measure IOP by patients,To evaluate agreement between IOPs from the Newton versus two other established tonometers (Goldmann applanation tonometer (GAT) and iCare).,To determine the specificity and sensitivity of Newton in measuring IOP versus Goldmann applanation tonometer (GAT) as the gold standard.,
Uganda 2024-07-23 14:44:42 2027-07-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John ILUNGOLE Stephen
ID:
EVALUATION OF THE EFFECTIVENESS OF UMEME WUUYO CAMPAIGN AGAINST POWER THEFT IN UGANDA
REFNo: SIR339ES

ii. To find out whether the public received the messages used in the Wuuyo communications campaign against power theft. ,i. To assess the effectiveness of campaign messages used in the Wuuyo campaign against power theft. ,To assess whether the Umeme Wuuyo Communications Campaign against power theft in Uganda was successful.,
Uganda 2024-07-22 17:18:00 2027-07-22 Engineering and Technology Non-Clinical Trial Degree Award
LAKER SCOVIA
ID: UNCST-2023-R006650
Antioxidants and Nutritional Potential of Enriched Millet Based Composite Flour Using Spirulina (Arthrospira platensis)
REFNo: A432ES

The objectives will be to; 1. determine the proximate composition (moisture content, ash content, fiber content and protein content) in non-germinated and germinated millet flours of eight selected local millet varieties (Ekwangapel, Ekaama, Emoro moru, Ayuku manyige, Odyera, Min bel, Luk caa and Adyang adyang). 2. determine the concentration of minerals (zinc, calcium, magnesium and iron) in non-germinated and germinated millet flours of eight selected local millet varieties (Ekwangapel, Ekaama, Emoro moru, Ayuku manyige, Odyera, Min bel, Luk caa and Adyang adyang). 3. determine the concentration of anti-nutritional factors (oxalates, tannins and Phytates) in non-germinated and germinated millet flours of eight selected local millet varieties (Ekwangapel, Ekaama, Emoro moru, Ayuku manyige, Odyera, Min bel, Luk caa and Adyang adyang). 4. determine the antioxidant potential (Beta carotene) in spirulina powder and germinated millet composite flours of three selected local millet superiors. 5. determine the consumer acceptability of the spirulina millet-based product (porridge) of three selected local millet superiors.
Uganda 2024-07-22 17:15:54 2027-07-22 Agricultural Sciences Non-Clinical Trial Degree Award
Alex Ario Riolexus
ID:
Surveillance System Performance, Timeliness Metrics and Framework of Response to Anthrax Outbreaks in Uganda: Implications for Programming and Control of Zoonotic Diseases Epidemics
REFNo: HS4277ES

4- Develop a One Health Model response framework for zoonotic disease outbreaks,3- Examine timeliness of response to anthrax outbreaks in Uganda for the period 2014 to 2023 and compare with 7:1:7 as a metric for strengthening response and improving systems in real time,2- Assess the human and animal anthrax surveillance system functions and attributes in Uganda,1- Identify gaps in epidemiological investigations of anthrax outbreaks in Africa for the period 2014 to 2023,The general objective of this study is to assess performance of the surveillance system and timeliness of response to anthrax outbreaks in Uganda, 2014 - 2023.,
Uganda 2024-07-22 17:13:33 2027-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Swaibu Zziwa
ID: UNCST-2022-R011017
MOBILITY RECOVERY AFTER A LOWER LIMB BONE FRACTURE; EFFECTS OF A MULTI- COMPONENT HOME BASED REHABILITATION PROGRAM ON MOBILITY RECOVERY IN GREATER KAMPALA, UGANDA
REFNo: HS4641ES

1.To describe the type of care received by patients with lower limb fractures after hospital discharge in Greater Kampala, Uganda. 2.To determine mobility recovery and predictors of mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda. 3.To develop and validate a multi component home based rehabilitation program to improve mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda. 4.To evaluate the effect of a multi component home based rehabilitation program on mobility recovery among patients with lower limb bone fractures in Greater Kampala, Uganda.
Uganda 2024-07-22 17:09:51 2027-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
AKANKWASA JOHNSON
ID: UNCST-2023-R006429
Factors Associated with Home Based Care Services in the Control of Covid - 19 Infection in Sheema Municipality, Sheema District
REFNo: SS2402ES

3.To establish the existing, new policies and practices about home based care agencies that addressed challenges resulting from the COVID-19 pandemic in the 3 years of the peak pandemic.,2. To establish the social demographic, social economic and environmental factors that affected home based care services (HBC) in all the COVID-19 suspects during 2019 pandemic.,1. To investigate the level of utilization of Home Based Care services (HBC) in percentages among the isolated COVID-19 suspects in the control of COVID-19 infection in Sheema Municipality from 2020 to 2023.,To establish factors associated with Home Based Care Services (HBC) during COVID -19 infection in Sheema Municipality, Sheema District.,
Uganda 2024-07-22 17:06:47 2027-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Mathias Seviiri
ID:
Genetics of Glaucoma in High-risk Diverse Populations (GoGLAD) Study
REFNo: HS3427ES

General objective
To apply and critically evaluate the efficacy of genetic-based risk prediction models for glaucoma in an understudied, high-risk, genetically diverse continental African population in Uganda.

Specific objectives
1. To test the feasibility of collecting quality pilot clinical data on glaucoma related phenotypes, genetic data from a unique high-risk diverse population in Uganda.
2. To assess cross-ancestry genetic-based prediction of glaucoma risk in major diverse ancestry populations.
2A- To apply our current European-based genetic prediction model of glaucoma to a high-risk population of African ancestry from Uganda.
2B - To develop, and calibrate an African ancestry genetic prediction model of glaucoma and implement it in populations of European and African ancestries.
2C- To develop, model and calibrate a cross-ancestry genetic prediction model and apply it in populations of European and African ancestries.
3. To apply artificial intelligence to eye images to characterise ancestral differences in glaucoma risk and evaluate estimation of disease risk and progression.
4. To assess participants’ attitude towards genetic testing for glaucoma.

Uganda 2024-07-22 17:03:10 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nura Izath
ID: UNCST-2022-R009201
Autothermo-a wearable continuous temperature measuring bracelet with a central display screen.
REFNo: HS3034ES

To assess the performance of Autothermo- a wearable continuous temperature measuring bracelet and a central display screen in comparison to the standard thermometer.,To assess the feasibility and acceptability of Autothermo among health workers and parents/caregivers of admitted neonates at Mbarara Regional Referral Hospital(MRRH).,
Uganda 2024-07-22 16:57:35 2027-07-22 Medical and Health Sciences Clinical Trial Non-degree Award
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