Kamya Moses
ID: UNCST-2020-R014203
|
Enhancing immunity to malaria in young children with effective chemoprevention
REFNo: HS1763ES
To compare the incidence of malaria from 4 weeks to 4 years of age among children born to mothers randomized to receive intermittent preventative therapy in pregnancy (IPTp) with monthly sulfadoxine pyrimethamine (SP) alone, monthly DP alone, or both monthly SP+DP.
To compare the incidence of malaria from 2-4 years of age among children randomized to receive IPT in childhood (IPTc) with monthly DP from 8 weeks to 1 year of age vs. monthly DP from 8 weeks to 2 year of age vs. no IPTc.
To compare innate and adaptive effector and regulatory responses between children randomized to different IPT arms.
|
Uganda |
2021-11-24 |
2024-11-24 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Emmanuel Viga Emmanuel
ID:
|
MORAL AND SOCIAL DIMENSIONS OF ACCOUNTABILITY IN CIVIC HUMANITARIANISM: RELATIONAL AID AMONGST SOUTH SUDANESE REFUGEES IN UGANDA
REFNo: SS832ES
This research will majorly attempt to answer the question How is accountability of relational aid in civic humanitarianism conceptualized and managed in protracted crisis. This will be achieved by answering the following sub questions:-
1. What differentiates civic humanitarianism from mainstream humanitarian actors?
2. What is relational aid within civic humanitarianism? and how is accountability understood within the concept of relational aid?
3. What are the accountability practices in civic humanitarian aid?
4- How do different accountability forms influence aid delivery?
|
Uganda |
2021-11-23 |
2024-11-23 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
DAN NYEHANGANE
ID:
|
CYCLOTIDES FROM MEDICINAL PLANTS OF UGANDA: SELECTED SOURCES, ANTIBACTERIAL ACTIVITY, AND CYTOTOXICITY
REFNo: NS258ES
Primary Objective: To identify cyclotides from selected medicinal plants in Uganda and establish their antibacterial activity and cytotoxicity, in order to provide a basis for their medical application in Uganda.
Specific Objectives
1.To determine the presence and quantities of cyclotides in different parts of selected medicinal plant species from selected families reported to express cyclotides and are used to treat bacterial infections in Uganda.
2.To characterize the activity of cyclotides from Ugandan plants in relation to sequence, size and structure
3.To determine antibacterial activities of cyclotides isolated from the different plant species stratified by the plant part extracted and season of harvesting the plant.
4.To determine the cytotoxic effect of the most active antibacterial cyclotide on mammalian cells
5.To determine the synergistic activity of the most active cyclotides against bacterial strains by using combinations of cyclotides from different plant species
6.To establish the anti-biofilm and immunomodulatory activity of the most active anti-bacterial cyclotides
|
Uganda |
2021-11-23 |
2024-11-23 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
|
Brenda McCollum
ID:
|
Muslims and Islam in Buganda, ca. 1900 - 1962
REFNo: SS950ES
I seek to examine the Muslim experience of colonialism in the Kingdom of Buganda.
|
USA |
2021-11-23 |
2024-11-23 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Rebecca Nalwanga Nalwanga
ID:
|
Exploring the Social and Institutional Dimensions of Disability in Primary Education: The Case of Inclusive Development in Uganda
REFNo: SS985ES
This research project aims to better understand the relationship between social development and disability in low-income countries. To achieve this objective, the research project will focus on how the experiences and positionality of primary school learners with a disability intersect with social development, education and democracy, and how these intersections can inform policy and practices to advance social, economic and political development in a low-income country such as Uganda.
|
Uganda |
2021-11-22 |
2024-11-22 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Faith Masette Bisikwa
ID:
|
Exploring Classroom Assessment Practices and its Impact on Preservice Teachers’ self-efficacy in a selected Primary Teachers college, Uganda
REFNo: SS993ES
I used questions instead of objectives
Main Question; How do tutors’ classroom assessment practices impact preservice teacher’s self-efficacy?
Subsidiary questions;
1.What are the common classroom assessment practices in Ugandan Primary teachers’ colleges?
2.How is classroom assessment, practiced in this PTC?
3.What is the relationship between assessment practices and preservice teacher’s self-efficacy?
4.How best can classroom assessment practices be done in PTCs to improve Preservice teachers’ self-efficacy?
|
Uganda |
2021-11-22 |
2024-11-22 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Cissy Kityo
ID: UNCST-2021-R013663
|
ACTIV-2/A5401: Adaptive Platform Treatment Trial for Outpatients with COVID-19
(Adapt Out COVID)
REFNo: HS1813ES
1.1 Co-Primary Objectives
1.1.1 Phases II and III: To evaluate safety of the investigational agent.
1.1.2 Phase II: To determine efficacy of the investigational agent to reduce the duration of COVID-19 symptoms through study day 28.
1.1.3 Phase II: To determine the efficacy of the investigational agent to increase the proportion of participants with nasopharyngeal (NP) SARS-CoV-2 RNA below the lower limit of quantification (LLoQ) at study days 3, 7, and 14.
1.1.4 Phase III: To determine if the investigational agent will prevent the composite endpoint of hospitalization due to any cause or death due to any cause through study day 28. Hospitalization is defined as ≥24 hours of acute care, in a hospital or similar acute care facility, including Emergency Rooms or temporary facilities instituted to address medical needs of those with severe COVID-19 during the COVID-19 pandemic.
1.2 Secondary Objectives
1.2.1 Phases II and III: To determine whether the investigational agent reduces a COVID-19 Severity Ranking scale based on COVID-19-associated symptom burden (severity and duration), hospitalization, and death, through study day 28.
1.2.2 Phase II and III: To determine whether the investigational agent reduces the progression of COVID-19-associated symptoms.
1.2.3 Phase II and III: To determine if the investigational agent reduces levels of SARS-CoV-2 RNA in NP swabs.
1.2.4 Phase III: To determine the efficacy of the investigational agent to increase the proportion of participants with NP SARS-CoV-2 RNA below the LLoQ at study day 3.
1.2.5 Phase II: To determine the pharmacokinetics of the investigational agent.
1.2.6 Phase II: To determine efficacy of the investigational agent to obtain pulse oximetry measurement of ≥96% through day 28.
1.2.7 Phase III: To determine if the investigational agent will prevent the composite endpoint of hospitalization due to any cause or death due to any cause through study week 72.
1.2.8 Phase III: To evaluate if the investigational agent reduces the time to sustained symptom resolution through study day 28.
|
Uganda |
2021-11-22 |
2024-11-22 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Francis Ssali
ID: UNCST-2021-R012134
|
A Phase 2, Open-label, Single-arm, Multicentre Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Efficacy of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to less than 12 years) who are Virologically Suppressed (TMC278HTX2002)
REFNo: HS1815ES
Primary Endpoints
• Area under the plasma concentration-time curve from the time of administration up to 24 hours post-dose of RPV, as derived from the intensive PK assessments.
• Incidence of grade 3/4 AEs, SAEs, HIV-related events (including acquired immune deficiency syndrome [AIDS]-defining illnesses and Stage-3-defining Opportunistic Illnesses in HIV Infection), and AEs leading to discontinuation of study intervention through 24 weeks of study treatment.
Secondary Endpoint
• Incidence and severity of AEs/HIV-related events and their relatedness to RPV through 24 and 48 weeks of study treatment.
• Change from baseline Movement.
• Viral genotype at the time of virologic failure through 24 and 48 weeks of study treatment.
• Treatment adherence, as assessed by the Pediatric European Network for the Treatment of AIDS (PENTA) adherence questionnaire and by study intervention accountability, through 24 and 48 weeks of study treatment.
|
Uganda |
2021-11-22 |
2024-11-22 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Jerome Kabakyenga Kahuma
ID: UNCST-2021-R013729
|
The A-Lite vein locator: “a non-invasive assistive medical device designed to improve vein visibility among patients requiring intravenous therapy.â€
REFNo: HS1547ES
Main Objective
1. To assess the efficacy, safety and impact of using an assistive medical device to aid vein visibility among patients requiring intravenous therapy.
Specific Objectives
1. To assess the safety and efficacy of the A-Lite vein locator among 10 adults in Uganda.
2. To investigate non-inferiority by assessing the performance of the A-Lite vein locator with respect to the existing standard of care among 48 adolescents in Uganda.
3. To determine the effectiveness of using the A-Lite vein locator for improving vein visibility among 156 children requiring intravenous cannulation in Uganda.
|
Uganda |
2021-11-19 |
2024-11-19 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Clare Tanton Tanton
ID:
|
Taking the Good School Toolkit to scale
REFNo: SS1035ES
The aim of the project is to determine the feasibility and acceptability of using Regional Resource Persons to deliver the Good Schools Toolkit in primary and secondary schools in Uganda and to relate markers of implementation to intermediate outcomes in teachers.
The specific objectives are:
1. To determine whether implementation of the Good Schools Toolkit through Regional Resource Persons can be done with fidelity and whether it is associated with attitudes towards violence against children and markers of school operating culture among teachers.
2. To understand Teacher Protagonists’ motivations, their perceptions of their role and how these evolve during intervention implementation. To understand Teacher Protagonists’ experiences and opinions of intervention mode of delivery and the support they receive from Regional Resource Persons and school administration, and their views on the main successes and challenges of this approach.
3. To understand the experiences of Regional Resource Persons in supporting schools and at different stages of intervention implementation. To understand Regional Resource Persons’ perceptions of the main successes and challenges they face during intervention implementation and how these challenges might be overcome.
4. To explore how the attitudes and behaviours of the Regional Resource Persons evolve following Good Schools Toolkit training and during their role supporting schools, and how this correlates with their performance.
5. To understand teachers’ experiences returning to school after prolonged COVID-related closures
|
UK |
2021-11-19 |
2024-11-19 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
ANGELLA MUSIIMENTA
ID: UNCST-2021-R013297
|
My Mobile Wallet: An Intervention to Support Access to Tuberculosis Care and medication Adherence in Rural Uganda
REFNo: HS1688ES
Assess the refined My Mobile Wallet intervention for larger scale feasibility, acceptability, and impact on TB treatment adherence and clinical outcomes. We will randomize 162 newly diagnosed TB patients (1:1:1) to SMS texts + incentives Arm A, SMS texts only B, and control Arm C (standard clinic-based TB care); follow-up will be the 6 month-treatment period. Feasibility and acceptability will be assessed per above. Impact will be based on electronically monitored medication adherence (primary), as well as treatment completion, clinic attendance, cure, and mortality (secondary).,Refine the My Mobile Wallet intervention. We will adapt the intervention to address any feasibility and accessibility issues raised in R21 findings. We will then pilot test the refined version of the intervention in 10 TB patients over two months of treatment to ensure optimal functionality. ,Assess the initial feasibility and acceptability of My Mobile Wallet. Forty patients with newly diagnosed TB will use My Mobile Wallet over their 6-month course of treatment. Feasibility will be assessed by appropriate receipt of the cash transfers and SMS texts, and intervention functionality. Acceptability will be assessed using System Usability Scale [53] and interviews based on the Unified Theory of Acceptance and Use of Technology [54].,Determine the optimal design and develop My Mobile Wallet as an intervention to support TB medication adherence. Through client-centered approaches, we will iteratively conduct focus group discussions with up to 30 TB patients to develop an optimal My Mobile Wallet intervention.,
|
Uganda |
2021-11-19 |
2024-11-19 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Noeline Nakasujja
ID: UNCST-2019-R001428
|
The impact of the COVID-19 pandemic and its response on the mental health of people with pre-existing mental conditions in Uganda.
REFNo: HS1781ES
5. To explore the experiences and views of people with SMI, their families/caretakers and mental health clinicians regarding the MMHC,4. To assess the effectiveness of an outreach mobile mental health clinic (MMHC)7 initiative to mitigate the care and messaging gap for people with SMI during the Covid-19 pandemic and its response.,3. To explore the experiences and viewsof people with SMI and their families/caretakers regarding COVID -19 and its response ,2. To assess the effect of COVID -19 and its response on access to care for people with SMI ,1. To assess the effect of COVID -19 and its response on the mental health of people with SMI ,
|
Uganda |
2021-11-18 |
2024-11-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Jack Rugasira
ID:
|
GREEN SUPPLY CHAIN PRACTICES AND ENVIRONMENTAL SUSTAINABILITY: A CASE OF SELECTED UGANDA MANUFACTURERS ASSOCIATION ENTITIES IN KAMPALA
REFNo: NS308ES
i. To determine the relationship between green sourcing and resource use efficiency in Kampala district.
ii. To determine the impact of green manufacturing on ecological balance in Kampala district.
iii. To assess the relationship between green transportation and availability of clean air and water in Kampala district.
iv. To determine the relationship between reverse logistics and wetland management in Kampala district
|
Uganda |
2021-11-18 |
2024-11-18 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
|
Thereza Piloya Were
ID: UNCST-2019-R000491
|
The Relation Between Mean Glucose and HbA1c in Ugandan Children and Youth with T1D: An Observational Study
REFNo: HS606ES
PRIMARY OBJECTIVES
1. To determine the relation between laboratory-measured HbA1c and mean glucose as measured by continuous glucose monitoring (assessed over 10-14 days per sensor period).
2. To determine the consistency of the relationship between laboratory- measured HBA1C and the mean glucose using multiple measurements in Ugandan Children and youth.
3. To determine the relation between laboratory-measured HbA1c and factors known to impact red blood cell survival.
SECONDARY OBJECTIVE
To determine the relation between point-of-care HbA1c and mean glucose in this population.
|
Uganda |
2021-11-17 |
2024-11-17 |
Medical and Health Sciences |
|
Non-degree Award |
|
Catherine Atuhaire
ID: UNCST-2021-R013090
|
A multi-morbidity study of diabetes mellitus, hypertension and Postpartum depression among postnatal mothers (MMDHAPPD) in Mbarara city, Uganda
REFNo: HS1836ES
To explore the challenges and coping strategies of mothers suffering from these multiple morbidities in Mbarara city, Uganda,To compare the serum cortisol levels of mothers diagnosed with and without postpartum depression,To determine the prevalence of hypertension among mothers diagnosed with postpartum depression in Mbarara city, Uganda ,To determine the prevalence of diabetes among mothers diagnosed with postpartum depression in Mbarara city, Uganda ,To assess the association between postpartum depression and either diabetes, hypertension or both among mothers in Mbarara city, Uganda,To determine the prevalence of postpartum depression based on the DSM-5 among mothers in Mbarara city, Uganda,To investigate the association between PPD and diabetes / hypertension or both and to explore the challenges and coping mechanisms experienced by these mothers suffering from these multiple morbidities in Mbarara city, Uganda,
|
Uganda |
2021-11-17 |
2024-11-17 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Leevan Tibaijuka
ID: UNCST-2021-R012986
|
Maternal comorbidities in pregnancy and post-delivery at Mbarara Regional Referral Hospital
REFNo: HS1734ES
3) To adapt a mobile application and assess the feasibility and acceptability of a pilot implementation of an intervention of sending appointments reminders and health education tips inform of SMS and pre-recorded voice messages to post-delivery women with co-morbidities to improve their compliance to follow-up appointments at MRRH. ,2) To compare the incidence of adverse maternal-fetal outcomes in women with and without medical co-morbidities and determine the predictors of adverse maternal-fetal outcomes among women admitted for delivery at MRRH. ,1) To determine the prevalence of and modifiable risk factors associated with medical comorbidities among pregnant and post-delivery women at MRRH.,To explore medical co-morbidities among pregnant and post-delivery women at Mbarara Regional Referral Hospital (MRRH),
|
Uganda |
2021-11-17 |
2024-11-17 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Janet SEELEY
ID:
|
African Prostate Cancer - Disparities in Outcomes in Uganda
(APC-DOUG)
REFNo: HS1790ES
Aim/goal of study (General Objective)
The African Prostate Cancer - Disparities in Outcomes in Uganda (APC-DOUG) study aims to evaluate the health system, socioeconomic and clinical factors that impact public hospitals across Uganda to deliver affordable interventions that improve and reduce inequalities in prostate cancer outcomes.
1.6 Specific objectives
1. To evaluate the current structure and organisation of clinical care for prostate cancer
2. To understand the socio-economic, cultural and geographic barriers to accessing care
|
UK |
2021-11-17 |
2024-11-17 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
ALLAN BAGUMA
ID: UNCST-2021-R012022
|
Effect of Covid-19 pandemic and national lockdown on utilization of childhood immunization services at Kisenyi health centre IV KCCA health facility in Kampala.
REFNo: HS1879ES
General Objective
To determine the effect of Covid-19 pandemic and national lockdown on utilization of childhood immunization services at Kisenyi health centre IV health facility in Kampala.
Specific Objectives
1. To determine the pre-lockdown childhood immunization coverage at Kisenyi health facility in Kampala.
2. To determine the coverage of child hood immunization at Kisenyi health facility in Kampala during the national lockdown.
3. To assess the barriers and facilitators of childhood immunization at Kisenyi health centre IV facility in Kampala during the covid 19 pandemic.
4. To determine the coverage of child hood immunization at Kisenyi health facility in Kampala post the national lockdown
|
Uganda |
2021-11-17 |
2024-11-17 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Ritah Kigonya
ID:
|
Enhancing Livelihood Outcomes in Biodiversity offset Schemes in Uganda’s Oil and Gas Industry’s CSR Strategies
REFNo: SS332ES
The overall objective of the study is to enhance incorporation of people’s use and cultural values of biodiversity during the design and implementation of biodiversity offsets.
The specific objects include;
Objective 1: Mapping the extent of biodiversity offset projects and their effects on community livelihoods.
Objective 2; Analyze the extent to which biodiversity-based livelihood compensation schemes (social offset schemes) attain their desire objectives.
Objective 3; Use lessons from biodiversity-based compensation schemes to ascertain who to compensate, what to compensate and how to compensate them during implementation of biodiversity-based livelihoods
|
Uganda |
2021-11-16 |
2024-11-16 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
JOSAPHAT KAYOGOZA BYAMUGISHA
ID: UNCST-2019-R001680
|
REPRODUCTIVE TRACT INFECTIONS AMONGST STUDENTS: ADDRESSING THE CHALLENGE AT MAKERERE UNIVERSITY
REFNo: HS1810ES
To determine the prevalence of RTIs among Makerere University students,To assess the Reproductive Tract Infections (RTIs) related knowledge, attitude and practices (KAP) of the Makerere University population.,To address the challenge of Reproductive Tract Infections amongst students by establishing the prevalence, knowledge of students towards RTIs and reducing the gap through use of youth friendly approaches.,
|
Uganda |
2021-11-15 |
2024-11-15 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
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