Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Catherine Mwesigwa
ID: UNCST-2019-R000988
Commercial Baby Food Consumption and Complementary Feeding Practices in Kampala
REFNo: HS1784ES

To explain the motivations for use of commercial baby foods among caregivers of infants and young children between 6-36 months in Kampala,To determine the proportion of caregivers that use commercial baby foods among infants and young children between 6-36 months in Kampala ,To determine the level of commercial baby food use for complementary feeding and the associated factors in an urban/peri-urban Ugandan sub-population of caregivers of infants and young children between 6-36 months in Kampala. ,
Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
Assessment of the HIV/AIDS legal, regulatory, and policy environment for key populations in Uganda
REFNo: HS1925ES

5 To develop recommendations on how the legal and policy framework affecting Key Populations can be improved to promote an enabling legal environment for the national response to HIV, particularly for key populations. ,4 To determine the extent to which the legal framework protects rights and promotes an enabling legal environment for the national response to HIV, particularly for people living with and affected by HIV and key populations. ,3 To analyze access to justice and law enforcement on HIV and human rights among key population and key service providers, access to legal support services, and law enforcement mechanisms. ,2 To assess the critical human rights issues affecting key populations and the extent to which the current environment addresses these.,1 To analyze existing HIV, health, and other related laws, regulations, and policy initiatives that impact the HIV response among key and priority populations in Uganda.,
Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
Laparoscopic Cases Database
REFNo: HS1909ES

The second aim of the study is to use this data in a future project examining new low-cost laparoscopic equipment. ,The first aim of the study is to compare laparoscopic practices in several countries. ,This study aims to examine current laparoscopic practices in Uganda and the United States.,
Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
Validating a 10-minute instrument-free prototype HIV p24/p37 assay for early infant diagnosis
REFNo: HS1854ES

Objectives of the research project:

Primary objectives
1. To determine the sensitivity of a novel instrument-free HIV p24 PoC assay
2. To determine the specificity of a novel instrument-free HIV p24 PoC assay
3. To determine the accuracy of a novel instrument-free HIV p24 PoC assay
4. To determine the positive predictive value of a novel instrument-free HIV p24 PoC assay
5. To determine the negative predictive value of a novel instrument-free HIV p24 PoC assay

Secondary objective
1. To determine the agreement of the novel instrument-free HIV p24 PoC assay results between two independent laboratory technicians.

15. Brief outline of research study design/methods:

Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ayiorwoth Harriet
ID:
Exploring academic-practitioner knowledge sharing in higher education institutions: A study of Uganda Management Institute
REFNo: SS1102ES

1. Explore the benefits that UMI academic staff and practitioners gain from sharing knowledge. ,1. Find out how UMI academic staff and practitioners address the challenges that they face in sharing knowledge. ,Establish the challenges that UMI academic staff and practitioners face in sharing knowledge,Explore how UMI academic staff and practitioners share knowledge,The purpose of this study is to explore and gain an in-depth understanding of academic-practitioner knowledge sharing at UMI,
Uganda 2021-12-02 2024-12-02 Social Science and Humanities Non-Clinical Trial Degree Award
Alfred Ecega Guli
ID:
HUMANITARIAN FOOD ASSISTANCE AND NUTRITION OUTCOMES AMONG CHILDREN UNDER FIVE YEARS IN UGANDA: A CASE OF SELECTED REFUGEE SETTLEMENTS IN WEST NILE.
REFNo: HS1912ES

1. What is the effect of food in-kind assistance on the nutrition outcomes among children under five years in selected refugee settlements in West Nile? 2. What is the effect of the cash-based transfer on the nutrition outcomes among children under five years in selected refugee settlements in West Nile? 3. What is the influence of agricultural inputs support on the nutrition outcomes among children under five years in selected refugee settlements in West Nile? 4. What is the effect of nutritional factors on humanitarian food assistance and nutrition outcomes among children under five years of age in selected refugee settlements in West Nile?
Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
michael taylor halford
ID:
Dry Rifting in the Albertine -Rhino graben (DRIAR)
REFNo: NS260ES

To conduct geological investigation of faulting associated with continental rifting in the magma poor rift environment in the northernmost western branch of the East African Rift System.
USA 2021-12-01 2024-12-01 Natural Sciences Non-Clinical Trial Degree Award
David  Sam Lackland
ID:
The psychological well-being of school-age South Sudanese children living in a refugee camp in Uganda
REFNo: SS938ES

RATIONALE
To the best of our knowledge, there are few studies trying to understand how South Sudanese refugee children thrive in settlements in Uganda, limiting the insight into their overall psychological well-being. Therefore, this study seeks to obtain a better understanding of how South Sudanese school-age refugee children experience their life in a refugee settlement in Northern Uganda.
The forced displacement of children implicates coping with and adapting to scenarios and situations that can be detrimental to a child’s normal development and well-being. To understand how children cope with the overall forced migration experience can contribute to find solutions to mitigate or reduce the potentially negative impact it has on children’s psychological well-being and mental health. By improving the knowledge about children’s experiences in refugee settlements, this study ultimately wishes to contribute with evidence that can facilitate the design and implementation of children friendly activities and environments in refugee settlements.
OBJECTIVES
In order to achieve the overarching aim mentioned before, this study plans to:
• observe how children play and socialize with each-other;
• understand how children learn in the refugee camp;
• explore how children cope emotionally with the different challenges caused by forced migration.
Norway 2021-12-01 2024-12-01 Social Science and Humanities Non-Clinical Trial Degree Award
Macreen Mudoola
ID:
HRL Mid term and end of program evaluation protocol
REFNo: HS1701ES

to assess the progress of the project
Uganda 2021-12-01 2024-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ezekiel Mupere
ID: UNCST-2021-R012739
Enhancing Integrated Management of Acute Malnutrition with Family MUAC and Implementation Science in West Nile Region in Uganda - Implementation Guideline Research Proposal
REFNo: HS1828ES

5. To assess the impact of IMAM Family MUAC on access, coverage of OTC and ITC and quality of care.,4. To determine the retention level of family caregivers and VHTs in detection and referral of children with acute malnutrition.,3. To determine the effectiveness of IMAM Family MUAC in detection and referral of acute malnutrition ,2. To assess the barriers and facilitators of IMAM Family MUAC implementation in in health facilities and communities in five districts in West Nile,1. To determine the uptake of IMAM Family MUAC in health facilities and communities in five districts in West Nile,To establish the feasibility and evaluation of the implementation process and effectiveness of IMAM Family MUAC to improve access, coverage, and quality of care in OTC and ITC services,
Uganda 2021-12-01 2024-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sina Kulwijira Sosthenes
ID:
Proportion of episiotomy and factors associated with episiotomy among mothers delivering at Mbarara regional referral hospital
REFNo: HS1552ES

To determine proportional of episiotomy and factors associated with episiotomy among mothers delivering at Mbarara regional referral hospital
2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Muhmood Kiryowa Haruna
ID:
Periodontal disease in diabetic patients attending Kiruddu Referral Hospital, Kampala: Prevalence, Factors and Association with Glycemic control and Insulin resistance
REFNo: HS1853ES

1) To determine the prevalence and factors associated with periodntal disease in patients with diabetes mellitus
2) To determine the bacteria associated with periodntal disease in patients with diabetes mellitus
3) To determine the association between periodntal disease and insulin resistance in patients with diabetes mellitus
Uganda 2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Victoria Namuggala Flavia
ID: UNCST-2019-R000991
Young Women and Men’s Aspirations and Resilience: Prospects for Livelihoods, Employment and Accountability before, during and beyond COVID – 19
REFNo: SS1093ES

The overall objective of this project is to explore and interrogate the aspirations and resilience of young women and men in Africa; how these may or may not have shifted through the COVID-19 crisis and the implications presented for public policy in Africa with case studies in Ethiopia, Ghana, Kenya, Nigeria, Rwanda, Senegal and Uganda. Specific objectives are to:
1. Examine Ugandan young women and men’s aspirations for their futures.
2. Identify and analyse gender and social norms that guide the lives and aspirations of young men and women in Uganda.
3. Establish whether young women and men’s aspirations have changed with the advent of COVID-19.
4. Analyse what the young women and men are experiencing in their lives and livelihoods in a COVID-19 world.
5. Determine the extent to which the various provisions, regulations and policies in the study countries are aligned with young women and men’s aspirations and ideas about what they see themselves doing in the future.
6. Document lessons learned about the adaptability and resilience of young women and men’s aspirations.

Uganda 2021-11-30 2024-11-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
Controlled Trial of Game Changers: A Group Intervention to Train HIV Clients to be Change Agents for HIV Prevention in Uganda
REFNo: HS1896ES

1. To conduct a fully powered RCT of Game Changers to test intervention effects on the primary outcomes of increased HIV testing, reduced condomless sex, and decreased enacted HIV stigma among social network members of participating PLWH.
2. To test intervention effects on the secondary outcomes of reduced internalized HIV stigma, increased HIV serostatus disclosure, and increased viral load suppression among participating PLWH, and PrEP uptake among their social network members.
3. To examine whether increased HIV prevention advocacy by PLWH mediates intervention effects on their social network members’ increased HIV testing and condom use, and whether increased HIV disclosure by PLWH mediates intervention effects on social network members’ reduced HIV stigma.
4. To conduct a cost-effectiveness analysis of the intervention.
We will recruit 210 PLWH, randomizing 105 to the intervention and 105 to a no-intervention control
Uganda 2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jenna Amlani Nahid
ID:
PATHWAYS FOR AGILE IMPLEMENTATION: IDENTIFYING THE ACTIVE ELEMENTS OF RAISING VOICES’ GOOD SCHOOL TOOLKIT
REFNo: SS1060ES

to elicit feedback from stakeholders on the program and specific activities to improve the GST ,to understand which aspects of the GST most important for changing relationships within schools and ultimately reducing violence against children ,
Canada 2021-11-29 2024-11-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
Social-spatial networks and Tuberculosis Infection in Children and Youth in Rural Uganda (SONET)
REFNo: HS1844ES

General Objective
To characterize, on a population-level, where and from which social network youth acquire TB infections and to assess variations throughout stages in the early life-course (early childhood: 1-5 years; school-age: 6-11 years; adolescence: 12-18 years).


Uganda 2021-11-29 2024-11-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arnold Moses  Okello Moses
ID:
Addressing Child Trafficking and Slavery in Uganda (ACTS)
REFNo: SS871ES

1. The Standards of Care (SOC) workstream seeks to develop evidence-based nationwide standards of care for survivors and victims of trafficking and slavery. This will involve a desk-based evidence review, online surveys, workshops with the staff of civil society organisations, and analysis of survivor workshop and monitoring and evaluation data collected by project lead Hope for Justice.
2. The Network Strengthening (NSing) component seeks to engage key stakeholders to strengthen internal technical capacity for the Coalition against Trafficking in Persons in Uganda (CATIPU). The aim of this workstream is to increase the capacity of this network of counter-trafficking civil society organisations to improve prevention, protection prosecution and partnership outcomes and capacity for increased collaboration with wider government structures. Therefore, the Unit of Analysis is the network (see Section 12, page 8 below for more detail).

Uganda 2021-11-26 2024-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan Babirye
ID: UNCST-2021-R013201
Analysis of formal and informal institutions of socializing places and their role in shaping vulnerability to HIV: a case of young people (15-24 years) working in socializing places in Uganda
REFNo: HS1536ES

This study aims to analyze formal and informal institutions of socializing places and their role in shaping vulnerability to HIV using a case of YPSP in Uganda. The specific objectives are:
1. To profile socializing places in Uganda and the young people who work in such places
2. To explore the formal and informal institutions of socializing places and their influence on HIV risk and vulnerability of YPSP
3. To determine how YPSP navigate workplace rules and procedures that expose them to HIV risk and vulnerability
4. To explore compliance gaps of the formal and informal institutions of socializing places with the existing laws and opportunities for reducing youth vulnerability to HIV in socializing places

Uganda 2021-11-25 2024-11-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
PURPOSE 1: GS-US-412-5624/ A Phase 3, Double-Blinded, Multicenter, Randomized Study to Evaluate Safety and Efficacy of Twice Yearly Long-Acting Subcutaneous Lenacapavir, and Daily Oral Emtricitabine/Tenofovir Alafenamide for Pre-Exposure Prophylaxis in Adolescent Girls and Young Women at Risk of HIV Infection. Version 2.0, dated 10 March 2021.
REFNo: HS1920ES

1. Primary Objectives i) To evaluate the efficacy of LEN for HIV PrEP in AGYW at risk of HIV infection. ii) To evaluate the efficacy of F/TAF for HIV PrEP in AGYW at risk of HIV infection. 2. Secondary Objectives/ end points i) To compare the efficacy of LEN with F/TDF for HIV PrEP in AGYW at risk of HIV infection. ii) To evaluate the efficacy of LEN for HIV PrEP in AGYW at risk of HIV infection in participants adherent to LEN. iii) To evaluate the efficacy of F/TAF for HIV PrEP in AGYW at risk of HIV infection in participants adherent to F/TAF. iv) To compare the efficacy of F/TAF with F/TDF for HIV PrEP in AGYW at risk of HIV infection. v) To evaluate the safety and tolerability of LEN, F/TAF, and F/TDF for HIV PrEP in AGYW at risk of HIV infection. vi) To evaluate the safety and tolerability of LEN and F/TAF for HIV PrEP in AGYW ≥ 16 to < 18 years of age who have sex with male partners and are at risk for HIV infection. 3. Exploratory objectives i) To assess the adherence rate to LEN as assessed by on-time LEN injection ii) To assess LEN plasma levels iii) To assess the adherence rate to F/TAF and F/TDF using intracellular TFV-DP levels in DBS. iv) To evaluate the acceptability of a once every 26 weeks LEN injection for HIV PrEP in AGYW at risk of HIV infection. v) To assess LEN plasma levels during pregnancy. vi) To explore concentrations of hormonal contraceptives in LEN participants.
Uganda 2021-11-25 2024-11-25 Medical and Health Sciences Clinical Trial Non-degree Award
Julie Teichroeb Annette
ID:
Social decision-making in Angolan colobus (Colobus angolensis ruwenzorii) and vervet monkeys (Chlorocebus pygerythrus) at Lake Nabugabo
REFNo: NS131ES

Understanding the effects of social constraints on group size and composition, movements, and foraging decisions.
Canada 2021-11-24 2024-11-24 Natural Sciences Non-Clinical Trial Non-degree Award
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