Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,915
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Robert Ssekitoleko
ID: UNCST-2019-R001716
 IMPACTS OF ENTEBBE HOSPITAL CLOSURE ON THE CLIENTS’ HEALTH STATUS DURING THE COVID-19 PANDEMIC IN UGANDA
REFNo: SS1425ES

2. To determine the extent of impacts on the health status of the previously registered clients of Entebbe RRH.,1. To understand the options used by patients to cope-up with access to necessary health services during the closure of Entebbe RRH.,To determine the impacts of Entebbe Regional Referral Hospital (ERRH) general services closure during the COVID-19 pandemic (March 2020 – April 2022) on registered and non-registered OPD clients in the Entebbe catchment area Uganda.,
 Uganda 2022-09-12 18:13:58 2025-09-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rita Nakalega
ID: UNCST-2019-R000599
 A NOVEL VIDEO-BASED INTERVENTION TO ENHANCE OPTIMAL UPTAKE OF MALARIA PREVENTIVE THERAPY: A PILOT STUDY OF A HEALTH EDUCATIONAL APPROACH TO MALARIA PREVENTION DURING PREGNANCY
REFNo: NS384ES

1. Develop the PreVent intervention,
 Uganda 2022-09-08 20:06:17 2025-09-08 Natural Sciences Non-Clinical Trial Non-degree Award
Lorenzo Casaburi
ID:
An Evaluation of Contract Farming for Biofortified Crops
REFNo: SS1416ES

Main objective. The modernization of the agricultural sector is a key process for economic growth. Which organizational forms can foster this modernization? In recent decades, academics, practitioners, and policymakers have looked at contract farming as a promising option to foster commercialization of smallholder-based agricultural sectors and improve farmers’ market access. Compared with spot markets, contract farming can exploit increasing returns to scale in processing, transport, and branding, can overcome failures in credit and information markets, and can reduce demand and supply risk. At the same time, compared with vertical integration, contract farming preserves smallholders’ land property rights and thus avoids the establishment of large plantations. In the proposed project, we will use a randomized experiment to evaluate the impact of contract farming on plot productivity and farmer income, and to study the returns to investment for the contract farming companies, once accounting for any defaults on in-kind input provision. The implementation of the contract farming intervention will be managed by two partner agricultural companies according to their standard business procedures. The research team will be in charge of running farmer surveys to measure the effect of the contract farming. The academic research team is collaborating with Harvest Plus, an international organization whose goal is to develop and promote new, more nutritious varieties of stable food crops with higher amounts of micronutrients.

Specific objectives:

1. First, we will study the impact of contract farming on agricultural production, income, and profits. In order to measure profits, we will collect detailed agricultural labor and wage data. We will also study the impact of the treatment on other income-generating activities, including non-agriculture business activities. Measuring agricultural production and income implies gathering information on total output harvested and output sold, prices, and costs of inputs (seeds, fertilizers, hired work, etc.). Similarly, we will also collect data on other potential non-agricultural activities the household may be involved
2. Second, we will assess the overall extent to which enrollment in the contract farming scheme affects farmer technology adoption and input intensity, both for biofortified beans and for crops not targeted by the contract. Outcomes of interest include land preparation costs, plantlets per acre, fertilizer and manure applications, crop maintenance, and agrochemicals/pesticides. We will collect data on farming tools used by the households, fertilizers, pesticides, etc. to quantify changes on these variables that may occur during the time span of the project.
3. Third, we will study whether joining the contract farming scheme has an impact on food security. There is debate over the impact of a shift to commercial farming, as this may involve focusing production on crops that are not directly consumed in the household (see, e.g., Schneider, 2010). We will collect data on food security in order to assess the impact of the treatment on this outcome. Specifically, we will ask to the farmers on coping strategies deployed during eventual hunger periods the household may suffer o have recently suffered.
4. Fourth, we will try to measure operating costs and benefits of the companies. In particular, we will use companies’ administrative data to measure the prevalence of farmer default and crop side-selling and thus to quantify the return on investment for the companies. Partner companies will provide a detailed dataset with the relevant variables needed to perform this analysis.
5. As an additional contribution, we will also study the determinants of smallholder participation: we will correlate the choice to join the contract farming scheme (in the treatment villages) with baseline characteristics of the farmers. Several scholars have expressed concerns over the contract farming model, suggesting it may exclude households that are less productive and poorer at baseline. The take-up analysis will assess whether this concern holds or not in our setting.
 Italy 2022-09-08 16:09:36 2025-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Allan Kalungi
ID: UNCST-2022-R009843
 Unravelling the genetic risk underlying common mental illnesses (major depressive disorder, generalized anxiety disorders, suicidality and attention-deficit hyperactivity disorder) and alcohol and substance abuse among a rural general population cohort in south-western Uganda
REFNo: SS1404ES

Unravelling the genetic risk underlying common mental illnesses (major depressive disorder, generalized anxiety disorders, suicidality and attention-deficit hyperactivity disorder) and alcohol and substance abuse among a rural general population cohort in south-western Uganda
 Uganda 2022-09-08 16:05:10 2025-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Noel  Namuhani
ID:
EVALUATING THE EFFECT OF A COMMUNITY HEALTH CLUB ON THE PREVENTION AND CONTROL OF SCHISTOSOMIASIS AMONG FISHING COMMUNITIES IN BUIKWE DISTRICT, CENTRAL UGANDA: A QUASI-EXPERIMENTAL STUDY
REFNo: HS2426ES

To design, implement and evaluate the effect of community health clubs on prevention and control of Schistosomiasis in fishing communities of Buikwe district.
 Uganda 2022-09-08 16:03:14 2025-09-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Senjovu Kaggwa Dan
ID:
Landscape analysis of health service quality–related information systems and practices and their links to health purchasing in Uganda
REFNo: SS1390ES

The main purpose is to take stock of existing and emerging systems and practices for promoting, measuring, and rewarding health service quality. This will involve conducting a rapid landscaping of quality-related information systems, initiatives, and practices in Uganda’s health system, using the adapted ThinkWell’s Rapid Landscaping Tool. The study is not intended to carry out a quality assessment but rather taking stock of the current systems and their ways.

Specific objectives: The Cooperation for Evaluation Research and Training (CERT) firm, has been hired by ThinkWell to populate the landscaping tool with information on:
a. The current systems and practices that promote, measure and reward quality of health services
b. Existing opportunities for designing purchasing policies in ways that promote the delivery of high-quality services

 Uganda 2022-09-08 15:59:49 2025-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ezekiel Mupere
ID: UNCST-2021-R012739
 Management practices and Outcomes of Indrawing Pneumonia in Children Aged 2-59 Months in Kamuli District Primary Health Facilities of Uganda
REFNo: SS1392ES

To examine the management (including oral treatment, which one, for how many days, or hospitalisation, with injectable antibiotics, how many days, and treatment adherence) of children 2-59 months of age with chest indrawing pneumonia presenting at the primary health care facilities in Uganda,To determine the outcome (survival status) by day 15 of children 2-59 months of age with chest indrawing pneumonia who present at the primary health care facilities in Uganda,
 Uganda 2022-09-08 15:57:50 2025-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Alison Comfort
ID: UNCST-2022-R011501
 Understanding individual- and social network-level factors affecting infant HIV testing to design social network interventions to increase testing of HIV-exposed infants
REFNo: SS1395ES

Aim 2: Conduct qualitative research to explore the mechanisms linking social networks to infant HIV testing,Aim 1: Estimate individual- and social network-level correlates of infant HIV testing,
 USA 2022-09-08 15:49:03 2025-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Pooja Upadhayay
ID:
Gastro-intestinal parasites, hormones, and behaviors of vervets (Chlorocebus pygerythrus) in human-modified habitat.
REFNo: NS349ES

The primary objectives are to investigate I) the possible interspecific parasite transmission by examining the degree of overlap in the parasite communities of vervets, humans, cattle, and dogs and II) the effects of parasites on hormones and behaviors of three neighboring vervet groups (intergroup comparisons) at Lake Nabugabo, Uganda.
Nepal 2022-09-08 15:35:09 2025-09-08 Natural Sciences Non-Clinical Trial Degree Award
Dan Tumusiime
ID:
Epidemiology of Rift Valley fever in Uganda
REFNo: HS2288ES

(i)To determine the spatial and temporal patterns of RVF and the associated environmental factors influencing its occurrence in Uganda
(ii)To determine the seroprevalence of RVFV antibodies among livestock and humans and associated risk factors for seropositivity at the farm level
(iii)To determine incidence rate of RVFV in livestock during inter-epizootic/inter-epidemic period

 Uganda 2022-09-08 15:33:16 2025-09-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Steven Atukwase Kabaringo
ID:
The military in peace keeping operations: Uganda 1994-2022
REFNo: SS1417ES

General objective

•To assess the nature of military peacekeeping operations

Specific objectives

•To examine the nature of military peace keeping operations.
•To analyse the roles of the military in peace keeping operations
•To examine the perception of the political and military and leadership on peace keeping deployments.

Uganda 2022-09-08 15:14:39 2025-09-08 Social Science and Humanities Non-Clinical Trial Degree Award
Winnie  Muyindike R
ID: UNCST-2021-R013558
 The Sentinel Research Network of IeDEA: A Prospective Cohort among People Living with HIV
REFNo: HS2217ES

Determine cross-sectional prevalence, incidence and progression over three years of liver enzyme (ALT/AST) elevation, non-invasive biomarkers of liver fibrosis (APRI, FiB-4, Fibroscan) and liver steatosis (CAP, Fatty Liver Index,Characterize the onset, chronicity and severity of mental health and substance use problems among older PLHIV over time as well as their interrelation and their influence on the HIV care continuum.,Determine the prevalence, incidence and predictors of cardio-metabolic disorders including diabetes mellitus, hypertension and dyslipidemia in PLHIV during a three-year follow-up period,To establish the IeDEA Sentinel Research Network (IeDEA-SRN)to prospectively capture and analyze standardized data among PLHIV in LMICs. Through this network, we further seek to implement studies focused on cardiovascular risk factors, mental health and substance use, as well as liver disease among PLHIV accessing HIV care in LMICs,
 Uganda 2022-09-06 15:07:47 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Docus Alowo
ID: UNCST-2022-R010834
 Prebiotic and probiotic capacity of ready-to-use composite foods developed from non-starch polysaccharides plant-based sources
REFNo: A226ES

Determine the strains with probiotic potential in fermented foods using composite flours ,Determine the microbial diversity of foods fermented using composite flours ,Determine the prebiotic capacity of the Fermentable oligo-di-mono-saccharides and polyols (FODMAPS) in plant based composite flours ,1) Identify Fermentable oligo-di-mono-saccharides and polyols in plant-based composite flours,To determine prebiotic and probiotic capacity of fermented foods developed using millet-sesame-soy composite flour,
 Uganda 2022-09-06 14:32:11 2025-09-06 Agricultural Sciences Non-Clinical Trial Degree Award
Paul Kitandwe Kato
ID:
Evaluation of the immunogenicity of candidate Rift Valley fever self-amplifying RNA vaccines in laboratory mice
REFNo: HS2408ES

To evaluate the humoral immune responses in mice of candidate saRNA vaccines encoding RVFV Gn and Gc sequences using a naked VEEV vector design To evaluate the cell-mediated immune responses in mice of candidate saRNA vaccines encoding RVFV Gn and Gc sequences using a naked VEEV vector design
Uganda 2022-09-06 14:30:17 2025-09-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Kenneth Odur
ID:
Assessing Community Perceptions on the State of Nutrition in Uganda. Focus Group Discussions and Key Informant Interviews in Lira District.
REFNo: SS1385ES

To impact malnutrition on the national and international level through research and dissemination.,To equip youth ambassadors in Ayami with knowledge and experience conducting qualitative research through focus groups and key informant interviews.,To equip community members in Ayami sub county with increased knowledge of the causes and consequences of malnutrition, as well as positive behaviors and resources to address malnutrition.,To assess community knowledge, attitudes, and beliefs on malnutrition and current malnutrition interventions.,To qualitatively assess implementation of the Uganda Nutrition Action Plan in Ayami sub county, Lira District.,
 Uganda 2022-09-06 14:29:01 2025-09-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Charles Kiyaga
ID:
A Validation Study to Compare the Performance of Gazelle Point-of-Care Device with Isoelectric Focusing and Capillary Electrophoresis in testing for Sickle Cell Disease in Uganda
REFNo: HS2319ES

c) To assess the usability and operational characteristics of Gazelle, including the ease of use, technical complexity and inter-reader variability.,b) To evaluate foetal haemoglobin (HbF) quantitation in SCD patients on hydroxyurea treatment, as compared to standard methods, in Uganda.,a) To determine the sensitivity and specificity of Gazelle in comparison to the standard tests used for the diagnosis of SCD.,
 Uganda 2022-09-06 14:24:20 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Musoke
ID:
Enhancing the capacity of Community Health Workers on epidemic and pandemic preparedness and response in Wakiso district, Uganda: impact evaluation and dissemination
REFNo: HS2349ES

Overall objective To carry out an impact evaluation of a recent project that enhanced the capacity of Village Health Teams (VHTs) on epidemic and pandemic preparedness and response (including COVID-19) in Wakiso district so as to generate information to enhance scale-up of interventions as well as inform future related activities. Specific objectives 1. To explore how the performance of VHTs in relation to epidemic / pandemic preparedness and response including COVID-19 was affected by the training. 2. To explore other effects of the training on epidemic / pandemic preparedness and response including COVID-19 to VHTs and their communities.
Uganda 2022-09-06 14:22:51 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Estimating the real-world effectiveness and determinants of effectiveness China Manufactured and other COVID-19 vaccines in Uganda
REFNo: HS2422ES

To determine the overall and product-specific rate of breakthrough infections (laboratory-confirmed SARS-CoV-2) among adult Ugandans vaccinated with China manufactured and other COVID-19 vaccines in Uganda,To estimate COVID-19 vaccine effectiveness (CVE) for more severe outcomes (e.g., ICU admission, or in-hospital mortality) and its determinants in among adults diagnosed with COVID-19 in Uganda,To determine the overall and product-specific effectiveness of China manufactured and other COVID 19 vaccines against symptomatic COVID-19 disease among adults diagnosed with COVID 19 in Uganda,
 Uganda 2022-09-06 14:21:36 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Wauyo
ID: UNCST-2022-R010247
 HOLISTIC MODEL FOR PREDICTING USER ADOPTION MECHANISM OF MOBILE APPLICATIONS FOR BUSINESS GROWTH IN MEDIUM ENTERPRISES: THE CASE OF KAMPALA CITY COUNCIL AUTHORITY
REFNo: SIR136ES

4. To propose a holistic model for predicting user adoption of mobile applications at KCCA,3. To test and validate the proposed model at KCCA,2. To determine factors that influence users intentions to adopt mobile applications at KCCA,1. To assess the existing mobile applications user adoption at KCCA.,The main research objective of this thesis is to “explain the mobile application adoption mechanism in the market and also build a holistic model that predicts user’s adoption of the third party mobile applications at KCCA.,
 Uganda 2022-09-06 14:20:08 2025-09-06 Engineering and Technology Non-Clinical Trial Degree Award
Roy Mayega William
ID: UNCST-2022-R010983
 Composition of honey sold on the Kampala market and its glycemic response among diabetic patients.
REFNo: HS2286ES

1) To characterise the carbohydrate composition of locally produced honey on the Kampala market.
2) To determine the organic composition of locally produced honey on the Kampala market.
3) To assess the Glycemic index of diabetic patients subjected to locally produced honey.


 Uganda 2022-09-06 14:18:12 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS