Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Christine Semambo Sempebwa
ID: UNCST-2021-R011977
 A Situation Analysis Of Refugees And Migrant Families Of Children Ages 3 To 8 In Uganda
REFNo: SS1126ES

PURPOSE: To analyze the overall refugees and the host community dynamics, highlighting issues surrounding inclusion/non-discrimination, diversity, and the influence of these issues on ECCE service provision and uptake. SPECIFIC OBJECTIVES: 1) Analyze the overall refugees and the host community dynamics, highlighting issues surrounding inclusion/non-discrimination, diversity, and the influence of these issues on ECCE service provision and uptake. 2) Assess the context and the most salient needs of 3 to 8 year old refugee and host community children and their families. 3) Investigate the factors affecting ECCE service provision and uptake of ECCE among refugee and host community populations. 4) Provide an evidence base that will inform the best ECCE programming for 3 to 8-year-olds affected by migration, along with those from the host communities. 5) Document lessons and best practices from the already existing ECCE service provision interventions that will inform Sesame Workshop’s programming.
 Uganda 2021-12-16 2024-12-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrea Felde Kronstad
ID:
Student Politics and mobilization in a Hybrid Regime: the Case of Makerere University, Uganda
REFNo: SS1122ES

The prime outcome of the study is to explain under which conditions the political system and system linkages affecting the organization, activity and substance of institutionalized and non-institutionalized student politics at Makerere University. The study aims to compare the effects on institutionalized student politics at Makerere University. Institutionalized student politics is operationalized as the Students Guild and non-institutionalized student politics is operationalized as Student Activism. The findings will be presented in 4 articles through an article based PhD dissertation.
Norway 2021-12-16 2024-12-16 Social Science and Humanities Non-Clinical Trial Degree Award
Mwebaze Nicholas
ID:
IMPLICATIONS OF AEROBIC EXERCISE ON CLINICAL OUTCOMES OF HIV POSITIVE CLIENTS IN UGANDA; A CASE OF GENERAL MILITARY HOSPITAL-BOMBO
REFNo: HS1276ES

1. To assess the effect of aerobic exercise on immunological measures of HIV positive clients on ART at GMH-Bombo.
2. To measure the effect of aerobic exercise on functional work capacity of HIV positive clients on ART at GMH-Bombo.
3. To determine the contribution of aerobic exercise on psychological markers of HIV positive clients on ART at GMH-Bombo.

Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Degree Award
Lillian Ayebale
ID:
Fertility desires, dilemmas and coping responses among adolescents in Kabira county Kyotera district.
REFNo: SS901ES

1. To review and examine the available evidence on fertility desires among adolescents in sub-Saharan Africa
2. To assess adolescents’ fertility dilemmas in relation to their fertility desires.
3. To explore adolescent coping responses relating to their fertility desires and HIV risk behavior
4. To examine the influence of parent-child communication on sexual matters on adolescents’ coping responses
5. To develop and conceptualizeand conceptualize a parent-child communication model for better ASRH outcomes

 Uganda 2021-12-15 2024-12-15 Social Science and Humanities Non-Clinical Trial Degree Award
Peter OReilly
ID:
Regionalism in East Africa c. 1900 to present
REFNo: SS923ES

This project aims to undertake the first comprehensive historical study of regionalism in East Africa across the 20th and 21st centuries. Attempts at formal economic and political integration in East Africa has been a common feature of the region’s history over the last century. This is evident today with East African Community’s (EAC) regional integration and cooperation agenda. However, there has been remarkably little historical and contemporary research on this theme that has sought unpack the continuities and disjunctures of regional integration in East Africa across this period. This reflects both an ingrained methodological nationalism in the field, and a tendency to assume the weakness of regional integration in Africa as compared to the supposed European ‘ideal type’. This project will therefore address fundamental questions relevant to the topic relating to the intellectual, political and economic drivers and obstacles to integration in East Africa in historical and contemporary perspective, and from a range of levels of analysis: national, regional and global. Research for this project will be conducted across the EAC’s founding members-states (Kenya, Tanzania and Uganda) and in important international and regional bureaucratic centres (Addis Ababa, Ethiopia; Abidjan, Côte d’Ivoire; Washington DC, United States; Brussels, Belgium).
 Ireland 2021-12-15 2024-12-15 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANGELLA MUSIIMENTA
ID: UNCST-2021-R013297
 Using Mobile Technologies to prevent Vulnerable Mothers from COVID-19 in Rural Southwestern Uganda
REFNo: HS1693ES

Implement the MobileMomCare app and carry out an endline assessment to evaluate its preliminary impact on prevention knowledge, risk perception, and adoption of COVID-19 prevention practices, coping mechanism, and system usability among 72 illiterate mothers,Develop scripts and multimedia videos/audios for COVID-19- prevention as well as information on preventing/coping with COVID-19-induced challenges such as domestic violence and HIV/AIDS.,Carry out a baseline study to quantitatively assess the COVID-19 prevention knowledge, risk perception, adoption of COVID-19 prevention practices, among 72 illiterate mothers,Assess the factors constraining the adoption of COVID-19 prevention practices utilized by rural illiterate mothers. ,To support the prevention of COVID-19 among rural illiterate, poor, and vulnerable mothers using a mobile phone-based multimedia application—MobileMomCare application,
 Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JUDE MULOWOOZA THADDEUS
ID:
QUALITY IMPROVEMENT PROCESS METRICS FOR CAESAREAN SECTION IN UGANDA, A LOWER-RESOURCE SETTING: DEVELOPMENT AND FEASIBILITY ASSESSMENT
REFNo: HS1768ES

Löfgren, J., Kadobera, D., Forsberg, B. C., Mulowooza, J., Wladis, A., & Nordin, P. (2015a). District-level surgery in Uganda: Indications, interventions and perioperative mortality. Surgery, 158(1), 7-16. https://doi.org/10.1016/j.surg.2015.03.022
Löfgren, J., Kadobera, D., Forsberg, B. C., Mulowooza, J., Wladis, A., & Nordin, P. (2015b). Surgery in district hospitals in rural Uganda-indications, interventions, and outcomes. Lancet, 385 Suppl 2, S18. https://doi.org/10.1016/s0140-6736(15)60813-3
Löfgren, J., Mulowooza, J., Nordin, P., Wladis, A., & Forsberg, B. C. (2015). Cost of surgery in a low-income setting in eastern Uganda. Surgery, 157(6), 983-991. https://doi.org/10.1016/j.surg.2015.01.026
Mulowooza, J., Santos, N., Isabirye, N., Inhensiko, I., Sloan, N. L., Shah, S., Butrick, E., Waiswa, P., & Walker, D. (2021). Midwife-performed checklist and ultrasound to identify obstetric conditions at labour triage in Uganda: A quasi-experimental study. Midwifery, 96, 102949. https://doi.org/10.1016/j.midw.2021.102949
Santos, N., Mulowooza, J., Isabirye, N., Inhensiko, I., Sloan, N. L., Shah, S., Butrick, E., Waiswa, P., & Walker, D. (2021). Effect of a labor triage checklist and ultrasound on obstetric referral at three primary health centers in Eastern Uganda. Int J Gynaecol Obstet, 153(1), 130-137. https://doi.org/10.1002/ijgo.13420
Shah, S., Santos, N., Kisa, R., Mike Maxwell, O., Mulowooza, J., Walker, D., & Muruganandan, K. M. (2020). Efficacy of an ultrasound training program for nurse midwives to assess high-risk conditions at labor triage in rural Uganda. PLoS One, 15(6), e0235269. https://doi.org/10.1371/journal.pone.0235269
Waiswa, P., Wanduru, P., Okuga, M., Kajjo, D., Kwesiga, D., Kalungi, J., Nambuya, H., Mulowooza, J., Tagoola, A., & Peterson, S. (2021). Institutionalizing a Regional Model for Improving Quality of Newborn Care at Birth Across Hospitals in Eastern Uganda: A 4-Year Story. Glob Health Sci Pract, 9(2), 365-378. https://doi.org/10.9745/ghsp-d-20-00156


GENERAL OBJECTIVE: To understand perspectives on caesarean patient care coordination and quality, develop a caesarean process quality assessment instrument, and assess feasibility, usability, and acceptability of the instrument through a pilot study in Iganga District Hospital in Eastern Uganda and its referring health centres.
SPECIFIC OBJECTIVES
1. To understand key stakeholders’ perspectives on patient flow through caesarean care pathways, including key transition and decision points, and opportunities for improving care efficiency and safety.
2. To understand providers’ views on currently employed and alternative caesarean process quality metrics.
3. To understand patient experiences of caesarean decision making and flow through caesarean care.
4. To develop a set of caesarean quality process metrics reflecting the importance of transdisciplinary high-quality care for improving CS-related outcomes
5. To understand the feasibility of assessment of the proposed caesarean process indicators.
6. To understand the usability of the proposed caesarean process indicators.
7. To test the validity of the proposed caesarean process indicators.
8. To compare the strengths and weaknesses of each indicator and approach.

 Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Winnie  Muyindike R
ID: UNCST-2021-R013558
 TB Risk by Alcohol Consumption
REFNo: HS1962ES

To determine the incidence of active TB disease among PLWH with prior LTBI, who received TPT, by level of alcohol use. To estimate the incidence rate of new TB infection among PLWH with prior negative TST results by level of alcohol use. To examine the risk of acquiring TB infection and of incident active TB disease among PLWH with heavy alcohol use after receipt of TPT in PLWH in Uganda.
 Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FREDDIE SSENGOOBA Peter
ID: UNCST-2021-R011834
 Landscape Analysis of Health Technology Assessment (HTA) Ecosystem in Uganda.
REFNo: HS1935ES

The main objective of the landscape assessment is to understand the current decision-making environment in Uganda’s health sector relevant to priority setting, including the identification of key stakeholders and interests, to support the development of a strategy to institutionalise HTA as an essential process for priority setting and evidence-informed decision making in Uganda’s quest for UHC.
Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christopher Tumwine
ID:
A QUALITATIVE STUDY OF THE AGRICULTURAL LIVELIHOOD SUPPORT PROGRAMME TO PERSONS LIVING WITH HIV IN UGANDA
REFNo: HS1954ES

To assess whether HIV programmes in Uganda still need to provide livelihoods’ support to persons living with HIV in the era-of test and treat. To examine clients’ perspectives on changes/benefits experienced as a result of participating in the agricultural livelihood support programme. To examine challenges which have been experienced by clients as result of participating in the agricultural livelihood support programme. To examine key stakeholders’ perspectives on the process, benefits and challenges of the agricultural livelihood support programme to HIV clients.
Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
 Anti-Retroviral Therapy Adherence Measurement Methods and Virological Failure in HIV infected Ugandans on long-term ART
REFNo: HS1949ES

1a. To describe incidence of virological failure in patients enrolled in the long-term ART cohort and assess the relationship between adherence to antiretroviral therapy (ART) measured either by patient self-report, appointment keeping and pill count and having virologic failure among HIV-infected Ugandan adults receiving long-term first line.
1b. To examine overall adherence measurement methods as a predictive test for VF among long term ART patients using a case control design taking patients confirmed with VF as cases and use incidence density sampling to sample for controls matched with time and age.
2. Determine the barriers and facilitators of ART adherence among patients on long-term ART at adult Infectious Diseases Institute (IDI) ART clinic using the Theoretical-Domains-Framework with 16 semi-structured, in-depth interviews with both people experiencing VF and those without VF, and ART providers (Medical Officers, Nurses, and counsellors)

 Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hella Peter Eszter
ID:
The effects of water shortage on female chimpanzee social behaviour in the Budongo Forest Reserve
REFNo: NS278ES

This research examines the space use and social behavior of female chimpanzees in the Budongo Forest Reserve, Uganda. In the forest, there are two habituated chimpanzee communities – Waibira, where habituation started in 2011, and Sonso, where habituation started in 1990. While both groups have high year-round food availability, the Waibira group faces an unusual ecological pressure during the annual dry season, when, despite being a rainforest-dwelling group, all permanent water sources within their home range dry up, with the exception of one waterhole. Describing how the female chimpanzees of the community are affected by this annually recurring water scarcity will help us understand the ecological pressures influencing chimpanzee social and ranging behavior. The project aims to provide a detailed description of the ranging of Waibira females, as well as their association patterns, levels of aggression, and gregariousness, and investigate whether any seasonal changes due to water availability are present. Other aims are to determine the dominance hierarchy of the females of the group, and to investigate whether individual factors influence strategies used to deal with water scarcity, such as increasing daily travel, or consuming more water-rich food.
Hungary 2021-12-13 2024-12-13 Natural Sciences Non-Clinical Trial Degree Award
ANGELLA MUSIIMENTA
ID: UNCST-2021-R013297
 Ethics of Using Digital Adherence Monitoring Technologies to Support Tuberculosis Medication (DATs Ethics Study)
REFNo: HS1692ES

Develop an initial framework for research and implementation of DATs in TB in Uganda, drawing from the ethical opportunities and challenges identified in Aim 1. ,Assess ethical opportunities and challenges associated with experienced DATs (electronic pill bottles, SMS) and emerging DATs (cell phone-based dose reporting, video calls, ingestion sensors) using the Consolidated Framework for Implementation Research. ,
 Uganda 2021-12-13 2024-12-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Michael Schwartz William
ID:
A Comprehensive Study of Human-Carnivore Conflict Mitigation and Prevention Measures in Queen Elizabeth National Park’s Unique Context of Human and Large Carnivore Ecology
REFNo: NS309ES

The following management-driven research proposal seeks to investigate human-carnivore conflict challenges in Queen Elizabeth National Park, Uganda through five interdisciplinary and transdisciplinary retro- and prospective studies (conservation sociology, community ecology, ecosystem services, wildlife ecology, and conservation biology) in the hopes of making informed, integrated, and strategic mitigation and prevention efforts. This includes 1) a compound cost-benefit analysis of fencing as a human-carnivore conflict (HCC) prevention and carnivore conservation measure; 2) a critical review of Uganda Carnivore Program’s (UCP) carnivore conflict mitigation and prevention efforts (with special emphasis on safe husbandry, experiential tourism, and compensation of genuine losses); 3) a brief review of large carnivore ecology, its resources needs, and current impacts of anthropogenic activity on large carnivore viability in Queen Elizabeth National Park; 4) competition-strategies and tactics of human ecology with wildlife ecology in Queen Elizabeth National Park and its impacts on ecosystem productivity and services; and 5) a critical cultural context review of local custodianship concepts vis-à-vis integrated management approaches (Resource Sharing Agreements, compensation, livelihood support etc.).
USA 2021-12-13 2024-12-13 Natural Sciences Non-Clinical Trial Degree Award
Eunice Ndirangu-Mugo Wambui
ID:
Understanding and informing the Development of Institutional Strategies for educational Resilience in online teaching and learning for undergraduate nursing and midwifery programs in Pandemic Times in East Africa (U-DISRUPT study)
REFNo: HS1923ES

1. Explore the perceptions of faculty and students towards online teaching and learning due to COVID-19
2. Determine students' and faculty preparedness with the transitioning to online learning during the COVID-19 pandemic
3. To establish the relationship between the online teaching presence, social presence, and cognitive presence among the faculty staff and students with the transitioning to online teaching during the COVID-19 pandemic
4. To assess the effects of the online teaching presence, social presence, and cognitive presence among the students with the transitioning to online teaching during the COVID-19 pandemic
5. Describe how to optimize the quality of online learning for the faculty and students in the university.

 Kenya 2021-12-13 2024-12-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HINDRAH AKISIIMIRE
ID:
KNOWLEDGE ACCESS AND SHARING THROUGH CULTURAL ASTRONOMY IN UGANDA’S REFUGEE SETTLEMENTS AND HOST COMMUNITIES.
REFNo: SS1116ES

To facilitate introduction of astronomy to the community of refugees.,To create an avenue of usefulness of institutional cultural astronomy knowledge in areas that may need purchase and use of physical gadgets,To provide a formal structure for knowledge storage and sharing,To catalogue cultural astronomy from refugees who are likely to lose this knowledge due to varying cultures and communities in the settlement camp.,To introduce astronomy to refugee settlements and gather information on the subject from the target communities. The gathered data from this project will be incorporated in a mobile astronomy lab for replication in other regions of Uganda.,
 Uganda 2021-12-13 2024-12-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Barbara Castelnuovo
ID: UNCST-2019-R000802
 Sero-prevalence of Severe Acute Respiratory Syndrome Coronavirus-2 antibodies amongst non-vaccinated People Living with HIV attending the Infectious Diseases Institute clinic
REFNo: HS1956ES

General Objective The objective of this study is to determine the seroprevalence of SARS-CoV-2 antibodies in non-vaccinated PLWHIV at high risk. This will generate information on the exposure of the SARS-CoV-2 virus in this population Specific Objectives 1. To determine the seroprevalence of SARS-CoV-2 antibodies amongst non-vaccinated PLWHIV at high risk. 2. To determine risk factors for the seroprevalence of SARS-CoV-2 antibodies amongst non-vaccinated PLWHIV at high risk
 Uganda 2021-12-13 2024-12-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Yang Jae Lee
ID: UNCST-2021-R012449
 Destigmatization of Mental Illness Through Theater
REFNo: HS1764ES

1. Primary Objective
Effectiveness of a community theater-based destigmatization program to combat stigma and increase care-seeking habits as measured by KAP (knowledges, attitudes, and practices) survey and focus groups at the beginning and the end of the intervention

2. Secondary Objective
1) Assess the general prevalence of mental health conditions for patients attending outpatient visits for general medical conditions
2) Assess KAP towards mental health of healthcare providers to shape future interventions in mental health destigmatization

 USA 2021-12-10 2024-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simon Kasasa
ID:
Evaluating the effectiveness of grouped intensive adherence counselling sessions in improving viral load re-suppression in Uganda
REFNo: HS1850ES

The main goal of this study is to evaluate the effectiveness of grouped intensive adherence counselling sessions in improving viral load re-suppression in Uganda.
The specific primary objectives of our study are as follows:
1. To compare the proportion of patients who have suppressed HIV viral load between those who have undergone grouped IAC relative to individualized IAC.
2a. To establish the PLHIV’s beliefs, and perceptions about receiving IAC using small patients groups relative to individual level.
2b. To establish the perceptions and experiences of HIV counselors about using grouped intensive adherence counseling scheme relative to the individualised scheme to deliver IAC messages.

Uganda 2021-12-10 2024-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Loduk Michael
ID:
Assessing the effect of patients’ health literacy levels on post-operative early surgical care outcomes at four rural-based hospitals in Western Uganda
REFNo: HS1907ES

MAIN OBJECTIVE:
to assess the effect of patients’ level of health literacy on early post-operative surgical care outcomes in (KIU-TH, Ishaka Adventist hospital, Comboni hospital Kyamuhunga, and Kitagata general hospital) the four rural-based hospitals in western Uganda.

SPECIFIC OBJECTIVES:
1. To assess the health literacy levels among patients receiving surgical care at the rural-based hospitals of KIU-TH, Ishaka Adventist hospital, Comboni hospital Kyamuhunga, and Kitagata general hospital.
2. To determine the early post-operative surgical outcomes of pain, wound infection at the surgical site, and patient’s well-being among the study population.
3. To establish the relationship between health literacy levels and early post-operative surgical outcomes among the study population.


Uganda 2021-12-10 2024-12-10 Medical and Health Sciences Non-Clinical Trial Degree Award
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