Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Carolyn Pelnik
ID:
School Management and Re-Enrolling Dropouts: Experimental Evidence from Schools in Rural Uganda
REFNo: SS1656ES

Which version of the program is more cost-effective in terms of gains to student learning: an intervention that assigns highly qualified university graduates to partner with community members to implement enrollment and remedial education activities, or an intervention where enrollment and remedial education activities are executed by community members alone? ,What is the effect of a school management intervention targeted towards the head teacher on school inputs (administrator time use and other measures of school functionality such as teacher attendance) and outputs (enrollment and learning, as measured by literacy and numeracy test scores)?,
USA 2023-03-09 23:39:42 2026-03-09 Social Science and Humanities Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
A Phase 2/3, Multicenter, Open-label, Multicohort Study Evaluating Pharmacokinetics (PK), Safety, and Efficacy of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in HIV-1 Infected, Virologically Suppressed Pediatric Participants.
REFNo: HS2646ES

The primary objective of this study is to confirm the dose of ATV/co or DRV/co in HIV-1 infected pediatric participants, to confirm the dose of F/TAF in HIV-1 infected pediatric participants and to evaluate the safety and tolerability these medications.
Uganda 2023-03-09 23:33:04 2026-03-09 Medical and Health Sciences Clinical Trial Non-degree Award
Pooja Chitneni
ID: UNCST-2021-R012955
Developing an STI partner notification services delivery intervention in southwestern, rural Uganda.
REFNo: HS2720ES

Explore facilitators and barriers to task-shifting delivery models for STI partner notification among healthcare workers, administrators, and potential patients. Also to develop a novel STI partner notification services delivery intervention for Uganda and similar settings.
USA 2023-03-09 22:41:48 2026-03-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph  Kampumure
ID:
FINANCIAL LITERACY, SELF-EFFICACY AND FINANCIAL INCLUSION AMONG WORKING WOMEN IN UGANDA
REFNo: SS1474ES

i) Establish the effect of financial literacy on financial inclusion among working women in Uganda. ii) Establish the effect of financial literacy on self-efficacy among working women in Uganda. iii) Determine the effect of self-efficacy on financial inclusion among working women in Uganda. iv) Determine the effect of self-efficacy on the connexion between financial literacy and financial inclusion among working women in Uganda.
Uganda 2023-03-07 11:05:55 2026-03-07 Social Science and Humanities Non-Clinical Trial Degree Award
Jiseon Chang
ID:
Empowering Developing Countries: Combating Misinformation and Correcting (Mis)perceptions of Foreign Aid
REFNo: SS1545ES

Understand how and when are perceptions of aid created
South Korea 2023-03-07 11:04:27 2026-03-07 Social Science and Humanities Non-Clinical Trial Degree Award
Patricia Ndugga
ID: UNCST-2022-R009605
Parent-adolescent communication on sexual and reproductive health in Kyotera border district, Central Uganda
REFNo: HS2702ES

The main objective of this study is to investigate the practice of SRH communication between parents and adolescents in Kyotera district, Central Uganda., 1. To determine the prevalence and factors associated with parent adolescent communication about SRH in Kyotera district. A cross-sectional survey for both parents and children will be conducted to establish the proportion of parents / children who discuss SRH issues, 2. Explore the approaches to, content and frequency of SRH communication between parents and adolescents in Kyotera., 3. To assess the community and district level stakeholders’ recommended strategies for improving communication of SRH between parents and adolescents.,
Uganda 2023-03-07 10:57:19 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
COVID-19 vaccine effectiveness and variants in Uganda: a test-negative case-control study with genetic sequencing (COVVAR)
REFNo: HS2672ES

Primary Objective To estimate vaccine effectiveness of licensed COVID-19 vaccines against laboratory-confirmed COVID-19 disease. Secondary Objectives 1. To identify circulating SARS-CoV-2 variants in Uganda. 2. To estimate vaccine effectiveness against specific SARS-CoV-2 variants identified by genetic sequencing. 3. To estimate vaccine effectiveness against severe COVID-19 disease. 4. To estimate effectiveness of COVID-19 vaccines against different SARS CoV-2 variants and different COVID-19 disease severities. Exploratory objective 1. To evaluate disease severity due to different circulating SARS CoV-2 variants
Uganda 2023-03-07 10:53:48 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DENIS MUGIZI RWABIITA
ID:
Assessment of meat handler training interventions on hygiene and disease detection in Ugandan slaughterhouses and meat retail outlets
REFNo: A266ES

Use syndromic surveillance to understand the incidence and distribution of important animal and zoonotic disease in Uganda,Assess the impact of mobile training tool on meat inspector knowledge,Assess the impact of nudges on knowledge and practices and food contamination at pork retail,Assess the impact of a targeted meat handler training on the knowledge, attitudes, and practices of meat handlers in Uganda.,
Uganda 2023-03-07 10:50:39 2026-03-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Raymond Tweheyo
ID: UNCST-2020-R014507
Understanding the effect of varied financial compensation structure for improving the performance, motivation and retention of Community Health Workers in Uganda - a quasi experiment
REFNo: HS2689ES

General objective: To understand the effect of varied financial compensation structure for improving the performance, motivation and retention of Community Health Workers in Uganda.

Specific objectives:
1. To determine the optimal performance based financial incentive incentive's structure required for improving the performance, motivation and retention of CHWs.

2. To explore the acceptability and perceptions of potential sustainability of CHWs financial compensation structure to various stakeholders, including the CHWs, and the CHW supervisors at the district and Ministry of Health.

3. To explore the perceived value and impact of financial incentives on CHW's job satisfaction, personal income and livelihood.
UK 2023-03-07 10:40:31 2026-03-07 Medical and Health Sciences Clinical Trial Non-degree Award
Stephen  Ojiambo Wandera
ID: UNCST-2021-R012147
Assessing Dementia and Frailty among Older Persons in selected rural districts in Eastern Uganda
REFNo: HS2693ES

Therefore, the aim this study is to determine the prevalence of frailty and dementia among older persons in rural Uganda. Specific aims of the study include:
Aim 1: To estimate the prevalence and factors associated with dementia among older persons in Uganda.
Aim 2: To estimate the prevalence and factors associated with frailty among older persons in Uganda.
Aim 3: To explore the experiences and perceptions of caregivers of older persons with dementia in Uganda.
In this study, we refer to point prevalence only.

Uganda 2023-03-07 10:36:00 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SONNY ASIMO
ID:
RISK FACTORS FOR FLUOROQUINOLONE RESISTANCE AMONG PATIENTS WITH SECOND LINE-DRUG RESISTANT TUBERCULOSIS EVALUATED AT THE UGANDA NATIONAL TUBERCULOSIS LABORATORY RefNo: CLARKE-2022-546
REFNo: HS2709ES

iii. To determine clinical factors associated with fluoroquinolone resistance in patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,ii. To characterize fluoroquinolone-resistance among patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,i. To determine the individual characteristics associated with fluoroquinolone resistance among patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,The study will determine the risk factors for fluoroquinolone resistance among patients with second-line drug resistant tuberculosis among previously evaluated samples in Uganda. ,
Uganda 2023-03-07 10:25:46 2026-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Perpetra Akite
ID: UNCST-2023-R008264
Systematic study of insect fauna in selected sites in Uganda (Insect Systematic Project)
REFNo: NS494ES

To sample a broad geographic area, including some of the never-collected or poorly-collected sites to yield new species that will be valuable to the insect systematic community and inform their conservation management
Uganda 2023-03-07 10:24:40 2026-03-07 Natural Sciences Non-Clinical Trial Non-degree Award
JOAN TUSABE
ID: UNCST-2021-R013942
FACTORS INFLUENCING UPTAKE AND ADHERENCE TO PREVENTION OF MOTHER TO CHILD TRANSMISSION (PMTCT) CARE AMONG REFUGEE HIV POSITIVE PREGNANT MOTHERS AGED 18 YEAS AND ABOVE IN KYANGWALI REFUGEE CAMP
REFNo: HS2711ES

1. To determine the level of uptake and adherence to prevention of mother to child transmission (PMTCT) services among refugee pregnant mothers aged 18 years and above in Kyangwali refugee camp

2. To determine factors associated with uptake and adherence to prevention of mother to child transmission (PMTCT) services among refugee pregnant mothers aged 18 years and above in Kyangwali refugee camp

3. To explore barriers and facilitators for uptake and adherence to prevention of mother to child transmission (PMTCT) services among HIV positive pregnant mothers aged 18 years and above in Kyangwali refugee camp


4. To determine strategies that can be put in place to improve uptake and adherence to prevention of mother to child transmission (PMTCT) among refugee HIV positive pregnant mothers in Kyangwali refugee camp?

Uganda 2023-03-07 10:23:51 2026-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Samson Udho
ID: UNCST-2021-R013728
Respectful maternity care in childbirth among adolescents aged 14 to 19 years in rural northern Uganda: a mixed-method study
REFNo: HS2727ES

The objectives are to: 1. Determine the prevalence of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 2. Determine the predictors of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 3. Explore the experiences of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 4. Explore the drivers of D&A of adolescents aged by SBA during childbirth in public health facilities in rural northern Uganda.
Uganda 2023-03-02 16:34:50 2026-03-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Fred Kaggwa
ID: UNCST-2022-R008842
Evaluating Mbarara University of Science and Technology (MUST) Internal Quality Assurance Mechanisms (IQAMs) on her Quality
REFNo: SS1629ES

General Objective
To evaluate MUST’s IQAMs on her quality using the IUCEA Model
Specific Objectives
1.To evaluate MUST’s IQAMs on the quality of Teaching and Learning
2.To examine MUST’s IQAMs on the quality of Research and Innovations
3.To assess MUST’s IQAMs on the quality of Community outreach

Uganda 2023-03-02 16:23:10 2026-03-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
ESTABLISHMENT AND EVALUATION OF CAPRI CELLS IN UGANDA FOR ADOPTIVE CELL THERAPY
REFNo: HS2684ES

1. Evaluate the reproducibility of Cascade Primed Cells with Apheretic collected Autologous PBMCs in Uganda
2. Test the effect of the reproduced CAPRI cells on Lung and Cervical cancer cells in vitro

Uganda 2023-03-02 15:39:34 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rachel Brathwaite
ID:
Assessing the Feasibility of Economic Approaches to Prevention of Substance Abuse among Adolescents
REFNo: HS2683ES

Aim 1. Examine the prevalence and consequences of ADU in a cohort of 200 AYLHIV (ages 18-24) seen at six (6) HIV clinics in southwestern Uganda.
Aim 2. Using a mixed methods approach, identify the multi-level (individual, interpersonal, community and structural) factors associated with ADU among AYLHIV.
Aim 3. Using a subset of the sample, explore the feasibility and short-term effects of a family-based economic empowerment intervention on ADU among AYLHIV.

Trinidad and Tobago 2023-03-02 15:32:31 2026-03-02 Medical and Health Sciences Clinical Trial Non-degree Award
NALWANGA ROSEMARY
ID:
Towards reconstructing latitudinal and altitudinal temperature gradients from the Last Glacial Maximum to the Present – Development of a globally applicable palaeothermometry method based on luminescence
REFNo: NS487ES

Reconstruction of surface air temperatures over the past 20,000-30,000 years along an
Achieve a better understanding of atmospheric dynamics in the tropics during the transition
from the Pleistocene to the Holocene
altitudinal gradient (lapse rate) and comparison to currently measured temperatures
Uganda 2023-03-02 15:14:46 2026-03-02 Natural Sciences Non-Clinical Trial Non-degree Award
Victoria Nambasa Prudence
ID: UNCST-2022-R008757
Landscape Assessment To Understand Maternal Vaccine Pharmacovigilance In Uganda
REFNo: HS2680ES

Main objective
The aim is to conduct a rapid assessment gap analysis and stakeholder mapping for safety monitoring of vaccines used in pregnancy and potential for use of Electronic Medical Record (EMR) for sentinel site surveillance in Uganda for post licensure studies as well as current tetanus and COVID-19 vaccination. The results of the assessment will inform areas of focus for establishment of robust safety surveillance of novel maternal vaccination and vaccines that maybe administered during pregnancy in pandemic situations in the country.
Specific objectives
1. Map stakeholders involved in regulation, policy setting, collection and reporting of adverse events following maternal vaccination and their linkages
2. Understand the existing methods, tools, and information flow for collecting and flow of adverse event following maternal vaccination
3. Mapping of current Electronic Health Record and registries roll-out and how they interface with national drug safety reporting system especially in relation to maternal vaccination
4. To understand the Community views, and perceptions on vaccination and reporting of AE during maternal immunization

Uganda 2023-03-02 15:08:39 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edmund  Mugayehwenkyi Kenneth
ID:
Women Rise Together across the Lifecourse (Write-Life)
REFNo: SS1633ES

3. What do women need to address their health and wellbeing issues and to feel more empowered? ,2. How empowered are women feeling? Document levels of perceived empowerment among women across the lifecourse, from young women through middle aged, to older women as well and capture the varied experiences of women in varied socioeconomic, cultural and community situations.,1. How are women doing? Examine associations between work (both paid and unpaid) and health throughout the COVID-19 pandemic among women across the lifecourse.,
Uganda 2023-03-02 14:46:12 2026-03-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
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