Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Florence  Nansumbi
ID:
Functional Indicators to assess freshwater ecosystem integrity: Biogeochemical dynamics of carbon, nitrogen and phosphorous cycling and stream metabolism
REFNo: NS402ES

The aim of this study is to evaluate the ecological status of sections of a Ugandan river with different levels of human impact using stream metabolism as a functional indicator.
It intends to investigate the following objectives:
i. To examine the role of catchment land-use and seasons in determining river water quality nutrient and dissolved organic carbon concentrations and the effects it has on water quality
ii. To investigate how stream metabolism responds to nutrient and organic matter loading along land use and seasonal gradients
iii. To assess the environmental parameters controlling stream metabolism in tropical streams and their seasonal variation along land-use gradients
iv. To investigate the relationship between stream processes and biological components of the river and their sensitivity to nutrient and organic matter pollution.

Uganda 2022-10-06 9:54:38 2025-10-06 Natural Sciences Non-Clinical Trial Degree Award
Joshua Kiptoo
ID:
SAFETY AND EFFECTIVENESS OF A SELECTED HERBAL MEDICINAL PRODUCT AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS IN MBARARA CITY, SOUTHWESTERN UGANDA.
REFNo: HS2440ES

To determine the cost-effectiveness of the selected HMP among patients with T2DM in Mbarara City.,To determine the safety of the selected HMP among patients with T2DM in Mbarara City.,To determine the effectiveness of a selected HMP among patients with T2DM in Mbarara City.,To identify the commonly used HMPs among T2DM patients in Mbarara City.,To evaluate the safety and effectiveness of a selected HMP among patients with T2DM in Mbarara City.,
Uganda 2022-10-06 9:53:17 2025-10-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anatoli Muleterwa
ID:
THE ROLE OF POLICING IN COUNTERING URBAN TERRORISM IN KAMPALA METROPOLITAN
REFNo: SS1436ES

General objective
The general objective of the study is to examine the influence of policing in countering urban terrorism in Kampala Metropolitan in order to reduce the incidents of terrorism through improving the working relationship between police and the community.
1.3.2 Specific Objectives
The specific objectives are;
1. To examine the role of police in countering urban terrorism in Kampala Metropolitan
2. To assess the effectiveness of police in identifying and countering urban terrorism in Kampala Metropolitan
3. To explore the role of community in countering urban terrorism in Kampala Metropolitan
4. To examine the relationship between police and community in countering terrorism in Kampala Metropolitan

Uganda 2022-10-05 15:07:23 2025-10-05 Social Science and Humanities Non-Clinical Trial Degree Award
Winnie  Muyindike R
ID: UNCST-2021-R013558
HIV-1 subtype-specific drug resistance in patients failing dolutegravir-based first-line, second-line or third-line regimens: multiregional study (DTG resist study)”
REFNo: HS2435ES

Main Objective 1.To determine the patterns and spectrum of InSTI DRMs in adults and adolescents with virologic failure on DTG-based ART by ART regimen and HIV-1 subtype. 2. To identify risk factors for virologic failure, InSTI DRMs, and InSTI drug resistance in adolescents and adults on DTG-based ART, including drug, host and health system factors. Specific Objectives 1a) To identify the prevalence of InSTI DRMs at the time of virologic failure. 1b) To compare the prevalence of InSTI DRMs at the time of virologic failure between HIV-1 subtypes and treatment contexts. 2a) To identify risk factors for Virologic Failure 2b) To identify risk factors for Drug Resistance Mutations. 3. To investigate correlations between novel resistance genotypes and phenotypic DTG resistance across HIV-1 subtypes.
Uganda 2022-10-05 15:04:09 2025-10-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jefferson  Mtongolo Mwaisaka
ID: UNCST-2022-R010784
An impact evaluation study of the Delivering Resilient Enterprises and Market Systems (DREAMS) project targeting refugees and host communities in Bidi Bidi and Rhino Camps, West Nile Uganda
REFNo: SS1445ES

To determine the cost-effectiveness of DREAMS compared to the status quo,To assess if there's any suggestive evidence that outcomes are substantially different for households that participate in both graduation and MSD programs vs households that only participate in graduation programs,To determine the impact of DREAMS on livelihoods, social cohesion, and perceived wellbeing among vulnerable households in host communities in Uganda’s West Nile refugee settlements,To determine the impact of DREAMS on livelihoods, social cohesion, and perceived wellbeing among vulnerable households in a refugee camp in Uganda’s West Nile refugee settlements,To determine the impact of DREAMS (poverty graduation + indirect MSD + direct market support) on livelihoods, social cohesion, and perceived wellbeing of vulnerable refugee and host community households in Uganda’s West Nile refugee settlements,
Kenya 2022-10-05 12:26:04 2025-10-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Samson Omongot
ID:
Validation of air pollution particulate matter measurements and characterization of the source apportionment using chemical speciation in urban Kampala.
REFNo: NS416ES

ii) To determine sources of pollutants using filter sampler Gravimetric Method in 12 months at Makindye & Kawempe divisions of Kampala district.,Specific objectives for Aim 2 i) To determine chemical composition of pollutants using filter sampler Gravimetric method in 12 months at Makindye & kawempe divisions of Kampala district,Aim 2 General Objective To determine the pollutants’ components in particulate matter (PM) and establish their specific sources using filter sampler gravimetric method in computer-based model Positive Matrix Factorization (PMF),iii) To assess the correlation of PM2.5 measurements between AirQo twin plan tower Monitor and filter sampler Gravimetric method,ii) To determine the correlation of the PM2.5 measurements between the filter sampler Gravimetric method, and the internationally standardized Kampala BAM ,Specific Objectives for Aim 1 i) To determine the correlation of PM2.5 measurements between AirQo twin plan tower monitors and the internationally standardized Kampala BAM ,Aim 1 General Objective To examine the correlation of ambient air pollution PM2.5 measurements between AirQo twin Plan tower Monitor (TPTM), filter sampler Gravimetric method and US Embassy Beta Attenuation Monitor (BAM).,
Uganda 2022-10-05 12:24:41 2025-10-05 Natural Sciences Non-Clinical Trial Non-degree Award
Wilfred Arubaku
ID:
Role of Physiotherapy in Ugandan Neurosurgical Transitional Care
REFNo: HS2369ES

3. To examine the knowledge, attitudes and beliefs of medical providers, rehabilitation providers, patients, and caregivers as to the inclusion of rehabilitation services in discharge practice.,2. To describe the experiences of discharge practice from the perspectives of medical providers, rehabilitation providers, patients, and caregivers.,1. To describe the process steps that are happening during discharge practice for medical providers, rehabilitation providers, patients, and caregivers.,This study aims to examine and understand the involvement of current rehabilitation professionals in discharge practices TBI and SCI patients in acute hospital settings. Results from this study will inform the development of care transition interventions that increase patient access and utilization of rehabilitation services to improve quality of life.,
Uganda 2022-10-05 12:23:17 2025-10-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
Reducing neonatal and maternal mortality by rapid detection of sepsis inresource-limited environments
REFNo: HS2439ES

To assess the perception of health workers on the use of the test for detection of neonatal sepsis in their units. To compare mortality rate within groups of neonates and mothers in whom SAA is detected and those in whom SAA was not detected in a resource-limited environment.
To characterise the clinical presentation and outcome of sepsis in all participants and information on treatment and duration.
To determine the detection of SAA following serial tests and treatment for neonates and mothers suspected to have sepsis.
To describe the proportion of neonates and mothers in whom serum amyloid A (SAA) is detected when expected to have neonatal or maternal sepsis versus available biomarkers.
To identify the technical barriers to implementing of the SAA lateral flow test for the detection of neonatal sepsis, and maternal sepsis.
To understand the non-technical barriers to implementing and adopting the SAA lateral flow test for detection of neonatal sepsis and maternal sepsis.
To evaluate and implement a pre-existing technology for the rapid detection of neonatal and maternal sepsis in a resource-limited environment.
Uganda 2022-10-03 17:37:34 2025-10-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Massy Mutumba
ID: UNCST-2022-R011366
Obuvumu: Improving Health Service Uptake for Survivors of Sexual Violence (SV)
REFNo: HS2364ES

This study seeks to inform the future development of culturally appropriate, feasible, acceptable and effective interventions to increase health service utilization among female survivors of sexual violence. The specific goals of this study are to:
Aim 1: Conduct formative qualitative research to inform a discrete choice experiment (DCE) that will generate systematic information on health service utilization for female survivors of sexual violence (SV) in Uganda;
Aim 2: Using a DCE approach, assess the factors that influence women’s decisions to seek services after experiencing SV among; and
Aim 3: Based on findings from the DCE, apply user-centered design principles to co-design an intervention that addresses barriers and preferences identified in Aims 1 and 2.
Uganda 2022-10-03 17:35:46 2025-10-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emma Riley-Green
ID:
A VILLAGE-LEVEL POVERTY ALLEVIATION PROGRAM IN UGANDA
REFNo: SS1431ES

Can poverty be alleviated effectively if everyone within a community is eligible for a graduation program, rather than only the poorest? Are the causes of persistent poverty specific to individual households, requiring individualized training and coaching, or are there common elements that can be addressed at the village level within group trainings?,
UK 2022-10-03 10:45:53 2025-10-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Henry Lugobe Mark
ID:
Cardiometabolic characteristics of women in Southwestern Uganda from pre-pregnancy to the postpartum period: a feasibility study
REFNo: HS2452ES

1. To examine the feasibility of recruiting to, conducting and completing a prospective cohort study on cardiometabolic characteristics from before pregnancy to the postpartum period among women in southwestern Uganda
2. To describe the cardiometabolic changes from pre-pregnancy to 3 months postpartum among women in southwestern Uganda
3. To determine the association between pre-pregnancy cardio-metabolic characteristics and hypertensive disorders of pregnancy among women in southwestern Uganda
4. To determine the association between pre-pregnancy cardio-metabolic characteristics and persistent hypertension at 3 months post-partum among women in southwestern Uganda

Uganda 2022-09-30 14:44:02 2025-09-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Fumi Okamoto
ID:
Availability of essential medicines and health supplies for primary care facilities in an eastern district of Uganda
REFNo: HS2390ES

This study objects to the supply of essential medicines in primary health care services in Uganda by investigating the availability of essential medicines in health facilities under local government to define the following. 1. Identify medicines and health supplies with low availability in primary care facilities. 2. Identify the characteristics of facilities with high availability of essential medicines in a district.
Japan 2022-09-30 14:42:10 2025-09-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Lydia Asiimwe Kyoma
ID:
Current Practices and Barriers to Prevention of Nosocomial Infections among Severely Acute Malnourished children at Mwana mugimu Nutrition Unit, Mulago National Referral Hospital.
REFNo: HS2308ES

1. To identify currently used prevention measured against nosocomial infections.
2. To find out the barriers that hinder compliance with health guidelines provided against nosocomial infections.
3. To determine what factors predispose SAM children to nosocomial infections.

Uganda 2022-09-30 14:41:19 2025-09-30 Medical and Health Sciences Non-Clinical Trial Degree Award
James Tumwine Kashugyera
ID: UNCST-2023-R007984
Bacterial zoonoses as a cause of non-malarial febrile illness in children in Uganda
REFNo: HS2330ES

1.To establish the prevalence of brucellosis, leptospirosis and Q fever in children with non-malarial febrile illness
2.To identify risk factors associated with brucellosis, leptospirosis and Q fever in children with non-malarial febrile illness

Uganda 2022-09-29 13:36:19 2025-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jennifer Verdolin
ID:
Testing the Feasibility of Community Driven Course Development: A New Paradigm in Equity, Diversity, and Inclusion
REFNo: NS364ES

Together with local community experts create two university level online courses in the areas of wildlife conservation and ecotourism. The courses, when offered to students outside of Uganda will incorporate profit sharing so that part of the tuition fees go back to the communities that helped develop the courses.

1. Collaborate with Conservation Through Public Health (CTPH) to connect with local community experts to
develop two online university courses in wildlife conservation and ecotourism.

2) Provide guest lectures and workshops to faculty at Kabale University on science communication and online course development

3. Conduct a special podcast series: Voices of Uganda where I invite community members and local experts to share their experience.

4. Develop a strategic plan development to recruit university partners
USA 2022-09-29 13:34:29 2025-09-29 Natural Sciences Non-Clinical Trial Non-degree Award
Joseph Wasswa Ziritwawula
ID:
IMPLEMENTATION OF NOISE POLLUTION CONTROL POLICY IN URBAN-UGANDA: ENFORCEMENT AND COMPLIANCE IN KAMPALA
REFNo: SS1221ES

1. To investigate the implementation of noise pollution control policy, in Lugaba City Division, Kampala Capital City.
2. To critically analyze the enforcement of noise control mechanisms, in Lugaba City Division, Kampala Capital City
3. To investigate citizens’ compliance with noise pollution control regulations, in Lugaba City Division, Kampala Capital City.
4. To inquire into citizens’’ perceptions on noise pollution control policy implementation, enforcement and compliance, in Lugaba City Division, Kampala Capital City.

Uganda 2022-09-29 13:31:58 2025-09-29 Social Science and Humanities Non-Clinical Trial Degree Award
Benedetta Lerva
ID:
Long-term Follow-up Surveys of the MasterCard Foundation Scholars Program
REFNo: SS1456ES

a) To investigate whether the program puts beneficiary students on a sustained human capital accumulation path and what are the
returns to secondary education generated by the program.
b) To investigate whether the program promotes gains in consumption, health,
assets, livestock holdings, and savings
c)Identify areas where the program successfully spurred systems change within partner schools, TVET institutions, employers, and/or the government; and
d)Evaluate the resilience of both Scholars and the educational system within the context of COVID- 19 shocks and identify potential areas where resilience could be further developed or strengthened.
Italy 2022-09-29 13:29:36 2025-09-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Alexandra Schubert Victoria
ID:
Implications of Chronic Pain Relief for Economic Decision-Making among Low-Income Individuals in Uganda
REFNo: SS1462ES

Discern the effect of pain relief on economic preferences (risk, time, and social preferences)

Implications of pain relief for labor supply and earnings. This will be studied to understand poverty-related income dynamics.

Implications of pain-relief for real-effort task game. The study of self-reported labor data will be completed by a small real-effort task game, where participants can earn additional income for sorting beans
Germany 2022-09-29 13:25:55 2025-09-29 Social Science and Humanities Non-Clinical Trial Degree Award
Francis Kiweewa
ID: UNCST-2020-R014929
A Global Multi-Center, Randomized, Blinded, Placebo-Controlled Phase 3 Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of SARS-CoV-2 mRNA Vaccine (LVRNA009) for the Prevention of COVID-19 in Participants Aged 18 Years and Older
REFNo: HS2476ES

The objective of this study is to evaluate the effectiveness, safety, and the ability of the study vaccine to provoke an immune response in your body against COVID-19. This study is necessary because the COVID-19 epidemic poses a significant global health challenge, and a large number of effective vaccines are still needed for the future. A total of approximately 34,000 participants like you from around the world, such as Africa and Asia will participate in this study. The entire study will last approximately 20 months, and your participation will last approximately at least 17 months. (The exact duration of your participation in the study may depend on the specific situation of the study. Please consult your study doctor at that time.)
Uganda 2022-09-28 14:10:52 2025-09-28 Medical and Health Sciences Clinical Trial Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
AN IMPACT EVALUATION OF AN INTEGRATED COMMUNITY-BASED MEDICAL AND PSYCHO-SOCIAL CARE AND GBV SENSITIZATION INTERVENTION FOR SEXUAL VIOLENCE SURVIVORS IN ADJUMANI, UGANDA
REFNo: HS2438ES

5. To evaluate the effectiveness of post-rape medical care and gender transformative GBV approaches integrated into existing community-based services in adolescents, adults, faith and non-faith leaders, CHW/Vs, and women-led organizations in refugee settlements and host population in Adjumani district.,4. To understand the extent to which the provision of community-level care following the event of sexual violence by CHWs in humanitarian settings is feasible. ,3. To assess the safety aspects of community provision of sexual violence care by community health workers (CHWs). ,2. To assess the extent to which community members have access to GBV prevention and care services (community or health centers) to receive medical and psychosocial care if needed.,1. To undertake an assessment of GBV Knowledge, Attitudes and Practices (KAP) of young people and adults in refugee and host communities within Adjumani district.,The general objective is to evaluate an enhanced version of the integrated community-based medical care for SV survivors model that includes gender transformative GBV prevention and response approaches based on the latest clinical guidance and social and behavioral change evidence in refugee settlements and host populations in Adjumani district so as to generate evidence that will inform evidence-based planning, implementation and form a basis for monitoring and evaluation of the program interventions. ,
Uganda 2022-09-28 14:08:14 2025-09-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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