Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ronald  Jjagwe
ID: UNCST-2024-R002922
A SITUATIONAL ANALYSIS ON THE EFFECTIVENESS OF TECHNOLOGY TRANSFER SYSTEMS IN UGANDA
REFNo: SIR395ES

The overall objective of the study is to analyse the ability of technology transfer systems to facilitate technology dissemination in Uganda. The specific objectives of the study are to: i) identify and map key actors in the technology transfer systems in Uganda; ii) determine the modes of technology transfer that exist in Uganda; iii) assess the effectiveness of technology transfer systems in Uganda and; iv) identify the strengths, weaknesses, opportunities and threats in technology transfer systems in Uganda.
Uganda 2024-10-16 21:33:10 2027-10-16 Engineering and Technology Non-Clinical Trial Non-degree Award
Asiati Mbabazi
ID: UNCST-2024-R005004
PERFORMANCE APPRAISAL, MOTIVATION AND TEACHERS' JOB PERFORMANCE IN SECONDARY SCHOOLS IN UGANDA: A CASE OF KASESE DISTRICT.
REFNo: SS2891ES

To establish the effect of motivation on teachers’ job performance in secondary schools in Kasese District.,To investigate the influence of performance review on teachers’ job performance in secondary schools in Kasese District,To determine the role of performance monitoring in teachers’ job performance in secondary schools in Kasese District,To assess the relationship between performance planning and teachers’ job performance in secondary schools in Kasese District,The purpose of this study is to examine the influence of performance appraisal, motivation on teachers’ job performance in secondary Schools, Kesese District, Uganda, in order to improve teacher productivity and students’ performance.,
Uganda 2024-10-15 9:00:31 2027-10-15 Social Science and Humanities Non-Clinical Trial Degree Award
Elizabeth namukwaya namukwaya
ID: UNCST-2021-R013177
Supporting undergraduate nurses palliative care education needs
REFNo: HS4672ES

To identify areas for reciprocal learning and shared learning priorities between these countries,To examine student nurses and educators experiences of palliative care education,To generate understanding of undergraduate palliative care nursing education in South Africa, Uganda, Ghana, New Zealand, Canada and the UK,
Uganda 2024-10-14 8:15:25 2027-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
A Phase III, Randomized, Double-Blind, Placebo-Controlled Study Evaluating Atezolizumab and Bevacizumab, with or without Tiragolumab, in Patients with Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (IMBRAVE152)
REFNo: HS5026ES

To evaluate the immune response to tiragolumab and atezolizumab,To characterize the PK profile of atezolizumab plus bevacizumab plus tiragolumab, To evaluate the safety of atezolizumab plus bevacizumab plus tiragolumab compared with atezolizumab plus bevacizumab,To evaluate the efficacy of atezolizumab plus bevacizumab plus tiragolumab compared with atezolizumab plus bevacizumab,
Uganda 2024-10-14 8:13:47 2027-10-14 Medical and Health Sciences Clinical Trial Non-degree Award
Isaac Ebiju
ID: UNCST-2024-R003903
Assessing the Impact of Summary Clinical Guidelines (charts and wheels) on Rational Antibiotic Use and Compliance with Uganda Clinical Guidelines Among Outpatient Prescribers: A case study of Health Centres III & IV in Kampala, Uganda.
REFNo: HS4926ES

To assess the impact and sustainability of summary clinical guidelines for improving compliance of prescription patterns with treatment guidelines on antibiotic use among prescribers at health Centers III and IV in Kampala, Uganda.,To analyze factors affecting guideline utilization among prescribers at health Centers III and IV in Kampala, Uganda.,To assess the compliance and prescription patterns of the Uganda Clinical Guidelines by prescribers at health Centers III and IV in Kampala, Uganda. ,To determine if the use of summary clinical guidelines improves the rational use of antibiotics and adherence to Uganda clinical guidelines among prescribers in outpatient departments of Health Centre IIIs and IVs in Kampala, Uganda.,
Uganda 2024-10-14 8:08:10 2027-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
Effects of Social Determinants of Health on Type 1 Diabetes (T1D) Care in Sub Saharan Africa; Perspectives from Uganda.
REFNo: HS5008ES

Primary
i. To describe the SDOH among the children and youths in Uganda.
ii. To determine the impact of SDoH on glycemic control of children and youths aged 6 months- 25 years in Uganda.
iii. To determine the effect of the SDoH on the physical growth of children and youths in Uganda.
Secondary
i. To set up a database of SDoH for children with T1D in Uganda.
ii. To determine the effect of the SDoH on the complications (DKA, severe hypoglycemia and hypertension) of children and youths in Uganda.

Uganda 2024-10-14 8:06:50 2027-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
Impact of Non-B HIV-1 Subtype on second-line Protease Inhibitor Regimens in Africa (INSPIRE)
REFNo: HS5035ES

To evaluate the effect of replicative fitness on susceptibility to PIs in patients with repeated failure in presence of known and novel Gag and Env PI-associated mutations.,To assess HIV-1 drug resistance in PI-resistant viruses using phenotypic drug susceptibility assay and recombinant viruses based on gag, pol, and env genes derived from patients failing 2L.,To determine the basis for second line (2L) treatment failures on ATV/r- and LPV/r-containing regimens in the absence and presence of protease-associated drug resistance.,To determine the effect of Non-B HIV-1 Subtype on second-line Protease Inhibitor Regimens in Africa.,
Uganda 2024-10-14 8:03:22 2027-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benjamin Eyre
ID: UNCST-2024-R002750
Enumerating development: how interdisciplinary perspectives on the treatment of research officers can improve data for social transformation
REFNo: SS3327ES

To generate new knowledge on FOs perspectives in relation to their work practices and conditions with a particular focus on how they see this affecting the quality of the data they produce. ,To explore challenges FOs negotiate, including low salaries, precarious employment contracts, pressure to perform quickly, working in dangerous environments, and negotiating knowledge hierarchies.,To document the lived experience of FOs working in the behavioural economics research sector in Uganda. Their work involves conducting surveys, experiments, and RCTs in informal urban settlements, peri-urban, and rural areas. ,
UK 2024-10-14 8:02:17 2027-10-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rosalind  Parkes-Ratanshi Parkes
ID: UNCST-2019-R000717
Providing Rapid HIV viral Diagnostics at Point of Care (The PROmPT) study.
REFNo: HS4881ES

Primary:
To evaluate quantitative performance of the HIV self-testing platform in a resource-limited setting (Uganda) compared to a laboratory-based, gold-standard FDA-approved HIV VL test (Roche Cobas Quantitative HIV-1 RNA, or Abbott Real Time HIV-1 assay, or similar) in PLHIV who have both viral suppression and non-suppression.

Secondary:
To evaluate patient acceptability of the HIV self-testing platform compared to gold standard VL assay
To compare the Turnaround Time (TaT) of the HIV VL self-testing assay and lab-based VL assay
To compare the assay performance of the HIV self-testing platform to lab-based testing by sex, age group, HIV viral load, HIV clade, and HIV risk group

UK 2024-10-08 18:13:17 2027-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mohamed Abouaziza
ID:
Evaluating Impact of Financial Incentives on Agri-Businesses in Uganda
REFNo: A520ES

The specific objectives are to determine whether access to incentivized loans generates increased credit for SMEs, and whether this additional credit subsequently leads to higher revenues, profits, and downstream outcomes for these businesses,The main objective of this research is to examine the effects of financial incentives offered to lenders on agricultural Small and Medium Enterprises (SMEs) while identifying and understanding the challenges these enterprises encounter. Specifically, the study aims to assess whether exposure to these incentives influences the volume of agricultural loans at the bank level and to understand the effects of these incentives on SME growth and performance at the SME level.,
Egypt 2024-10-08 18:11:59 2027-10-08 Agricultural Sciences Non-Clinical Trial Non-degree Award
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