Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Gooreka Okahaabwa
ID:
Contextual Factors for Peer Victimization of High School Students in Mukono
REFNo: HS2363ES

To compare the magnitude of peer victimization by contextual factors, among high school students in Mukono district.,To investigate the perspectives of peer victimization among high school students in Mukono district.,To explore the lived experiences of peer victimization among high school students in Mukono district,To determine the magnitude of peer victimization among high school students in varied contexts in Mukono District, The objective of this study is to investigate the magnitude of peer victimization and its contextual factors among high school students in Mukono, Uganda.,
 Uganda 2022-07-28 9:27:59 2025-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Loyce Asire Allen
ID:
Stakeholders’ Interventions in Addressing the Socioeconomic Barriers to Refugee Women Access to Higher Education: A Case of Bidibidi in Northern Uganda
REFNo: SS1369ES

Main objective
To explore stakeholders’ interventions in addressing the socioeconomic barriers to refugee women’s access to higher education in Uganda with Bidibidi settlement as a case study.

Specific objectives

1. To investigate stakeholders’ interventions towards addressing gender roles and norms that obstruct Bidibidi refugee women’s access to higher education;

2.To establish stakeholders’ interventions towards addressing sexual violence that obstructs Bidibidi refugee women access to higher education;

3.To examine stakeholders’ interventions in addressing financial constraints that obstruct Bidbibidi refugee women access to higher education.

 Uganda 2022-07-28 9:26:23 2025-07-28 Social Science and Humanities Non-Clinical Trial Degree Award
Douglas Bulafu
ID: UNCST-2021-R011774
 Awareness on occupational biohazards, and utilization of Personal Protective Equipment among sanitation workers in fecal waste management plants in Uganda
REFNo: HS2352ES

To explore the barriers and facilitators to utilization of personal protective equipment among sanitation workers in fecal waste management plants. ,To establish the level of utilization of personal protective equipment among sanitation workers in fecal waste management plants.,To determine the level of awareness of occupational biohazard risks among sanitation workers in fecal waste management plants.,To assess the awareness of occupational biohazard risks and utilization of personal protective equipment among sanitation workers in fecal waste management plants in regional cities in Uganda.,
 Uganda 2022-07-28 9:21:28 2025-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Chris. Opesen Columbus
ID:
Baseline Study for Our Rights, Our Lives, Our Future Plus (O3 Plus) Project in Uganda
REFNo: SS1354ES

Using the findings of the baseline study, the results framework will be completed with baseline indicator data and the correct data sources.,In addition, the baseline will collect comprehensive information on health service delivery for young people in line with existing national youth friendly service (YFS) guidelines and standards,Specifically, the baseline study will provide both quantitative and qualitative indicator data in-line with the proposed results framework as appropriate, and additionally provide an assessment of readiness of HTEIs to provide data for the result framework ,The purpose of this baseline study is to provide an information base against which to monitor and assess progress during implementation and after completion. ,
 Uganda 2022-07-28 9:19:52 2025-07-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
CHRISTINE NAMULINDWA ODWORI
ID:
EVALUATION OF PERFORMANCE OF COVID-19 TESTING CAPACITIES IN CLINICAL LABORATORIES IN UGANDA
REFNo: HS2252ES

iv. To evaluate the performance of COVID-19 public health capacity in clinical laboratories in Kampala district.,ii. ToTo evaluate the performance of COVID-19 data management capacity in clinical laboratories in Kampala district.,iii. To evaluTo evaluate the performance of COVID-19 biorisk management capacity in clinical laboratories in Kampala district.,To evaluate the performance of COVID-19 testing function in clinical laboratories in Kampala district,To evaluate the performance of COVID-19 testing capacities among clinical laboratories in Kampala.,
 Uganda 2022-07-28 9:18:11 2025-07-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Isa Kabenge
ID: UNCST-2021-R011727
 Machine learning for estimating sources and sinks: Developing cloud computing-based, artificially intelligent algorithms to quantify livestock and biomass for management of GHG emissions
REFNo: SIR91ES

Objectives:
The overall objective of the proposed project is to develop a novel methodology quantifying GHGs Inventory for a particular area by optimizing application of remote sensing, machine learning and artificial intelligence to quantify ranging animals as sources, above ground biomass and ground as sinks and incorporates animal management system.

Specific Objectives:
1) To develop an algorithm that optimizes, machine learning and artificial intelligence to quantify ranging animals, from remotely sensed imagery.
2) To develop an algorithm that optimizes, machine learning and artificial intelligence to index animal management systems, from remotely sensed imagery.
3) To develop an algorithm that optimizes, machine learning and artificial intelligence to quantify above ground biomass and ground, from remotely sensed imagery.
4) To develop a novel artificially intelligent algorithm for quantifying GHGs Inventory for a particular area by integrating, number of animals as sources, above ground biomass and ground as sinks and animal management system indexes quantified from remotely sensed imagery.

 Uganda 2022-07-28 9:16:58 2025-07-28 Engineering and Technology Non-Clinical Trial Non-degree Award
Philip Nyeko Nyeko
ID:
HEALTHYNSECT - Insect farming for health and livelihoods
REFNo: A118ES

The overall aim of HEALTHYNSECT is to assist policy development for accelerating rural insect farming and consumption of insects and insect-based products in Africa for sustainable development and improved nutrition, health, and livelihoods.
The specific objectives of the HEALTHYNSECT project are:
Objective 1
1. To develop an evidence-based framework describing impact pathways from incentivizing insect farming and consumption to intermediate and long-term development outcomes related to nutrition, health and livelihoods.
Objective 2
To conduct a multi-site factorial intervention study to identify and quantify the pathways for enhancing the adoption of insect farming and consumption of insects and insect-based products.
Objective 3
To assess the impacts of incentivizing insect consumption through provision of insect-based food supplements on household dietary diversity, and young children’s diet, health and nutritional status in rural households
Objective 4
To assess the impacts of incentivizing small-scale insect farming on household livelihoods and resilience including production and dietary diversity, food security perception, resource allocation, income generation, and household agricultural asset composition.
Objective 5
To support research capacity building and regional East-West research collaboration in Africa for strengthening research capacity on edible insects in sustainable food systems.
 Uganda 2022-07-27 10:14:51 2025-07-27 Agricultural Sciences Non-degree Award
Edith Akankwasa
ID:
Baseline Evaluation of the Comprehensive and inclusive disability prevention services project for Mildmay Institute of Health Sciences version 1.2, version date: 22.7.2022
REFNo: HS2334ES

The objective of the baseline survey is to assess access to Comprehensive and inclusive disability prevention services in the community and also the support that families with persons with disability are provided with (“What is SWOT Analysis in Project Management.Definition & Examples,” n.d.)
• To establish the parenting practice and attitude to care the children of children with disabilities;
• Understand the supportive relationships from community to most vulnerable children and their families.
• Capacity of local partners to effectively coordinate and support CWDs and the referral mechanism

 Uganda 2022-07-26 9:57:58 2025-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
LYDIA  KISEKKA NAMATEEFU
ID: UNCST-2022-R011079
 APPRAISING THE RELATIONSHIP BETWEEN THE LAW ON LAND REGISTRATION IN UGANDA AND LAND GRABBING: A CASE STUDY OF KAYUNGA DISTRICT
REFNo: SS1204ES

To appraise the relationship between the law on land registration and the phenomenon of land grabbing in Uganda.

Specific Objectives
i. To conceptualize the law on land registration and the practice of land grabbing in Uganda with a specific focus on Kayunga District.
ii. To identify the nature and causes of land grabbing in Kayunga District.
iii. To conceptualize the impact of land grabbing on the economy of Uganda using Kayunga District as a case study.

Uganda 2022-07-26 9:53:21 2025-07-26 Social Science and Humanities Non-Clinical Trial Degree Award
Atupele Mlangwa Subira
ID:
PREVALENCE AND FACTORS ASSOCIATED WITH PROLONGED HOSPITAL STAY FOLLOWING CAESEREAN DELIVERY AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: NS383ES

2. To determine the factors associated with prolonged hospital stay following caesarean delivery at MRRH,1. To determine the prevalence of prolonged hospital, stay following caesarean delivery at MRRH,To determine the prevalence and factors associated with prolonged hospital stay following caesarean delivery at MRRH,
 Tanzania 2022-07-26 11:29:37 2025-07-26 Natural Sciences Clinical Trial Degree Award
Barbara Alungat
ID:
THE URBAN POLICING PARADOX IN UGANDA: A CASE OF KAMPALA CITY
REFNo: SS1365ES

To explore the current responses by the police in enhancing urban peace enforcement in Kampala city.,To analyse the challenges of urban policing and peace enforcement in Kampala city. ,To examine the role of the Police in urban policing and peace enforcement in Kampala city. ,To explore the crimes accompanying rapid urbanisation in Kampala city,To examine the paradox of urban policing in Uganda with specific regard to how rapid urbanisation poses challenges for policing and urban peace enforcement in Kampala city even in the face of expansion and adequate tooling and equipping of the UPF.,
 Uganda 2022-07-26 10:07:57 2025-07-26 Social Science and Humanities Non-Clinical Trial Degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
 Knowledge, attitudes and practices regarding Tuberculosis among communities in the Karamoja sub region, North Eastern Uganda.
REFNo: HS2342ES

Overall Objective
To establish knowledge, attitudes and practices of communities in the Karamoja sub region towards Tuberculosis prevention, diagnosis and treatment.

Specific Objective 1: To determine factors associated with correct knowledge about TB prevention, diagnosis and treatment.

Specific Objective 2: To understand patterns of behavior associated with TB prevention, diagnosis and treatment in the Karamoja subregion


 Uganda 2022-07-26 10:04:18 2025-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Schola  Matovu Nakachwa
ID: UNCST-2022-R011040
 Development of an Intervention Designed to Promote Economic Empowerment, Social Support, and Health of Grandmothers who Provide Primary Care for Grandchildren in Uganda.
REFNo: SS1376ES

To pilot a small intervention as informed by the refined intervention to test its acceptability and feasibility among Ugandan grandmother-caregivers 50 years and older (N=15).,To develop and refine the intervention components based on information gathered in objective 1 and through an iterative feedback process from the CAB. ,To use a formative community-engaged research approach to inform the development of a multicomponent intervention for grandmother-caregivers.,To use a formative community-engaged research approach to inform the development of an intervention that will promote economic empowerment, peer group support, and health education geared towards improving the quality of life andthe mental and physical health of grandmothers who provide primary care for grandchildren affected by HIV/AIDS and poverty in Uganda. ,
 USA 2022-07-25 12:36:36 2025-07-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 An assessment of Multiple COVID-19 vaccine roll out in Uganda: exploring barriers and facilitators to inform better program design
REFNo: HS2101ES

(4) Explore COVID-19 roll out and its effect on the implementation of routine vaccination.,(3) Assess the uptake and perceived hindrances to the issuance of the multiple vaccines in the country ,(2) Examine the availability and preparedness of the health workers to rolling out the multiple vaccines in the study districts ,(1) Explore the process of issuance, adherence to guidelines and the facilitators to the multiple COVID-19 vaccine roll out in Uganda ,To understand the roll-out process of multiple COVID-19 vaccines in the country, its barriers and facilitators. ,
 Uganda 2022-07-25 12:34:15 2025-07-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frank NAMUGERA
ID:
Adoption and sustained use of efficient energy-saving technology (firewood cooking stoves) in Rwampara district, rural western Uganda.
REFNo: SS1346ES

To assess the impact of the adoption of improved cookstoves in communities near Bugamba forest, Rwampara District in western Uganda. Specific objectives: 1. To assess the knowledge, attitudes and practices of households towards energy consumption and quality of life in areas around Bugamba forest. 2. To assess the behavioral change patterns of individuals following the construction of the improved cookstoves. 3. To assess the changes in the quality of life of the communities after the adoption of the ICS. 4. To ascertain the impact of the adoption of clean energy cooking on the environment in the communities near Bugamba forest.
 Uganda 2022-07-25 11:14:17 2025-07-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
PRISCILLA KASEMBO
ID:
REPORTED ADVERSE DRUG REACTIONS OF ANTIRETROVIRAL THERAPY GENERIC FORMULATIONS IN UGANDA
REFNo: HS2042ES

1.To assess the reported adverse drug reactions of the first line ART generic formulations containing Tenofovir, Lamivudine and Efavirenz or Dolutegravir (TDF/3TC/EFV or DTG)in Uganda.

2.To document the reported ADRs of the first line ART generic formulations containing TDF/3TC/EFV or DTG at National Pharmacovigilance Center, Kisenyi HC4, Kiswa HC 3 and Mildmay hospital in Uganda
3.To compare ADR profiles by severity between different ART generic formulations containing TDF/3TC/EFV or DTG.
4. To compare the ADR profile between the two first line ART regimens (DTG and EFV based generic formulations).
5. To explore ADR reporting among health workers at Kisenyi HC4, Kiswa HC 3 and Mildmay hospital in Uganda, in reference to particular first line ART generic formulations (TDF/3TC/EFV or DTG).


 Uganda 2022-07-22 15:00:41 2025-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Winny Akullo Nekesa
ID:
Adoption of Linked Data among University libraries in Uganda
REFNo: SS1338ES

The study will address the following specific objectives:
1. Determine the level of awareness of Linked Data among the professional librarians in Ugandan Universities.
2. Establish the extent of Linked Data adoption in Ugandan Universities.
3. Determine the potential benefits of adopting Linked Data in Ugandan Universities.
4. Investigate the factors that influence the professional librarians’ behaviour towards the adoption of Linked Data in Ugandan Universities.
5. Investigate the strategies to promote the adoption of Linked Data in Ugandan Universities.

 Uganda 2022-07-21 11:01:06 2025-07-21 Social Science and Humanities Non-Clinical Trial Degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 A PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF ADJUVANT ATEZOLIZUMAB OR PLACEBO AND TRASTUZUMAB EMTANSINE FOR HER2-POSITIVE BREAST CANCER AT HIGH RISK OF RECURRENCE FOLLOWING PREOPERATIVE THERAPY
REFNo: HS2173ES

8. To validate the ability of fertility biomarkers to diagnose and predict permanent loss of ovarian function, and to determine the impact of anti-cancer therapy on hormone levels,7. To evaluate health status utility scores of patients treated with atezolizumab when given in combination with trastuzumab emtansine compared with placebo and trastuzumab emtansine,6. To identify and/or evaluate biomarkers that are predictive of response to atezolizumab and trastuzumab emtansine (i.e., predictive biomarkers), are early surrogates of efficacy, are associated with progression to a more severe disease state (i.e., prognostic biomarkers), are associated with acquired resistance to atezolizumab and trastuzumab emtansine, are associated with susceptibility to developing adverse events or can lead to improved adverse event monitoring or investigation (i.e., safety biomarkers), can provide evidence of atezolizumab and trastuzumab emtansine activity (i.e., pharmacodynamic biomarkers), or can increase the knowledge and understanding of disease biology and drug safety,5. To evaluate the immune response to atezolizumab and trastuzumab emtansine,4. To characterize the PK profiles of atezolizumab and trastuzumab emtansine when given in combination,3. To evaluate the safety of atezolizumab when given in combination with trastuzumab emtansine compared with placebo and trastuzumab emtansine,2. To evaluate the efficacy of atezolizumab when given in combination with trastuzumab emtansine compared with placebo and trastuzumab emtansine in the PRO-evaluable analysis set,1. The secondary efficacy objective for this study is to evaluate the efficacy of atezolizumab when given in combination with trastuzumab emtansine compared with placebo and trastuzumab emtansine in both the ITT population and PD-L1-positive population,The primary objective for this study is to evaluate the efficacy of atezolizumab when given in combination with trastuzumab emtansine compared with placebo and trastuzumab emtansine in both the ITT population (all comers) and the PD-L1-positive population (defined as all patients from the ITT population with a centrally assessed PD-L1-positive status [i.e., PD-L1 status of IC1/2/3] at randomization),
 Uganda 2022-07-21 11:00:02 2025-07-21 Medical and Health Sciences Clinical Trial Non-degree Award
Sonia Michaelsen Ingrid
ID:
Sexual and gender-based violence against South Sudanese Refugees in Uganda: A mixed-methods case study
REFNo: SS1029ES

The overall objective is to explore and compare the perceptions and experiences of sexual and gender-based violence (SGBV) towards South Sudanese refugees in Uganda who live in designated settlements to those who self-settled. More specifically:
1.To estimate the prevalence of SGBV among South Sudanese refugees in Ugandan settlements vs. those who have self-settled in urban areas
2.To identify the risk and protective factors of SGBV amongst South Sudanese refugees in designated settlements vs. urban areas, from the perspective of South Sudanese refugees and local community leaders and decision makers
3.To explore the relationship between the estimated prevalence of SGBV in settlements and urban areas and the risk and protective factors identified by participants
4.To generate context-dependent, stakeholder-led solutions to reduce SGBV in each setting

 Canada 2022-07-21 10:50:50 2025-07-21 Social Science and Humanities Non-Clinical Trial Degree Award
Odoi. Agricola
ID:
Challenges of Diabetes Management in Rural and Urban Areas of Uganda
REFNo: HS2358ES

Our central hypothesis is that diabetics in rural and semi-rural areas of Uganda may not be storing insulin at the appropriate temperatures due to absence of refrigeration facilities. This may impact the efficacy of this life-saving medication resulting in poor diabetes management and potential complications. We also hypothesize that diabetes patients face other challenges that constrain proper disease management such as lack of knowledge on diabetes management, risk factors and complications. Thus, the specific aims of this study are to determine: (a) how diabetic patients in Tororo district, Uganda, manage their diabetes; (b) how the patients store their insulin; (c) general patient knowledge of diabetes management best-practices and complications; (d) the sources of medical advice used by diabetes patients; and (e) the patient-reported challenges of diabetes management. Tororo District has been chosen because it is one of the marginalized areas of the country and hence the burden of the problem in Tororo will be representative of the situation in other less advantaged parts of the country. The findings of this study will be useful for in a number of ways (a) guiding future studies in these resource poor populations; (b) guiding diabetes management and control programs; (c) since practicing physicians will be involved in the study, the findings will be useful in informing their own clinical practice and understanding of how best to help their patients; (d) development of contextually appropriate educational interventions that may be adapted and implemented across not only Uganda but the other East African countries to counteract the emerging diabetes epidemic.
 Uganda 2022-07-20 17:56:33 2025-07-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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