Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Damari Atusasiire
ID: UNCST-2024-R002645
 A cluster- randomised controlled trial to assess the effectiveness and impact of the Tiko platform on increasing access to sexual and reproductive health (SRH) services among Adolescents and Young People (AYP) in Uganda
REFNo: SS3858ES

To assess whether the Tiko Model increases the modern Contraceptive Prevalence Rate (mCPR) among adolescents and young people in treatment areas relative to control areas.
To determine if there is a reduction in unintended pregnancies.
To evaluate improvements in knowledge, perceived norms, and attitudes towards contraception and HIV services (testing, ART, and PrEP).
To assess whether there is an increase in the uptake of HIV testing, ART, and PrEP.
To determine if there is an increase in access to high-quality, youth-friendly health services.
To examine whether there is a reduction in the HIV test positivity rate.
To assess improvements in the continued use of short-acting contraception and retention in ART and PrEP.
To evaluate whether there is an improvement in the number of Couple Years of Protection (CYP) offered.
 Uganda 2025-05-07 18:25:50 2028-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Victoria Isika Kiasyo
ID: UNCST-2025-R017083
 WOMEN'S DIGITAL SAFETY: Measurement for bolstering policy response
REFNo: SS3824ES

1. Conduct formative, human-centered research. We plan to co-create an instrument and contextualize our understanding of TFGBV, we will hold co-creation workshops with women and institutional stakeholders. 2. Translate formative human-centered findings to measurement. We will use qualitative insights from Aim 1 to compare local findings with existing TFGBV measures (developed mostly in high-income settings). 3. Pilot novel measure of TF-GBV exposure. We will pilot a quantitative instrument and submit this in an amendment to this ethics proposal. This amendment will specify the instrument, sampling, data collection procedures, analytical plan, community engagement and dissemination plan. Briefly, a long-list of items will be tested through quantitative surveys delivered both in person and digitally. Output from these surveys will enable us to validate and refine the instrument before dissemination.
 Kenya 2025-05-07 18:23:51 2028-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Winnie Kibone
ID: UNCST-2023-R008421
 Navigating Dual Diagnoses: Experiences of Individuals Living with Sickle Cell Disease and HIV in Uganda
REFNo: HS5859ES

1. To explore the experiences of people living with SCD and HIV in Northern and Central
Uganda
2. To determine indications for hospitalization, co-morbidities and clinical outcomes of
patients with SCD in Northern and Central Uganda
 Uganda 2025-05-07 18:22:49 2028-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Uganda Paediatric Antiretroviral Treatment study on uptake and long term outcomes on dolutegravir in Children and Adolescents living with HIV in Uganda (UP-ART DTG study).
REFNo: HS5830ES

Primary objectives: 1.To describe the uptake of DTG in the UP ART cohort and characteristics at start of dolutegravir (DTG)- based regimens (DBRs) 2.To describe mortality and loss to follow-up among CALHIV after start of DBRs 3.To assess the effectiveness of DBRs by assessing viral load (VL) response over time on DBR (viral suppression and viral failure) Secondary objectives: 4.To identify factors associated with viral failure 5.To assess the number/proportion of CALHIV discontinuing DTG and reasons for discontinuation 6.To assess changes in weight, height and body mass index (BMI) over time on DBR In analyses for Objectives 1-6, the key results will be presented overall and stratified by the following characteristics at start of DBR (where sufficient numbers n>20): a)Age at start of DBR: <2, 2 to <6, 6 to <12 and 12 to <20 years b)ART history and VL status at start of DBR: Naive, ART-experienced and suppressed (VL<1000 copies/mL), ART experienced and viremic (VL?1000 copies/mL) and ART- experienced and unknown VL. The VL status is based on most recent measurement within 6 months of start of DBR. c)DTG regimen: DTG/ABC/3TC, DTG/TDF/3TC, other DTG-based regimen
Uganda 2025-05-07 18:21:47 2028-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AGNES SANSA
ID: UNCST-2025-R017934
 MULTI-GENERATIONAL WORK ETHICS, INCLUSIVITY, DIVERSITY MANAGEMENT PRACTICES AND THE PERFORMANCE OF PUBLIC AGENCIES IN UGANDA
REFNo: SS3782ES

i. To establish the relationship between multigenerational work ethics and the performance of public agencies in Uganda. ii. To assess the influence of inclusivity in the relationship between multigenerational work ethics and the performance of public agencies in Uganda. iii. iii. To examine the effect of diversity management practices in the relationship between multigenerational work ethics and the performance of public agencies in Uganda. iv. iv. To determine the joint effect of multigenerational work ethics, inclusivity and diversity management practices on the performance of public agencies in Uganda.
Uganda 2025-05-07 18:19:31 2028-05-07 Social Science and Humanities Non-Clinical Trial Degree Award
Joel Ongom
ID: UNCST-2024-R015752
 Impact of Dichrostachys cinerea management interventions on Soil Properties and subsurface Macrofauna in Queen Elizabeth National Park, Uganda
REFNo: NS902ES

1. To determine the effect of management intervention on D.cinerea by excavation and burning on the physico chemical properties of soil.
2. To assess the effect D.cinerea management intervention in QENP on the abundance and diversity of above ground soil macrofauna
3. To assess the effect D.cinerea magement interventions in QENP on the abundance and divesity of below ground soil macrofauna

 Uganda 2025-05-07 18:17:57 2028-05-07 Natural Sciences Non-Clinical Trial Non-degree Award
Mohamed Farah Mohamud
ID: UNCST-2025-R016841
 EFFECTIVENESS OF INTRAVENOUS PETHIDINE VERSUS INTRAVENOUS TRAMADOL FOR PERIOPERATIVE ANALGESIA IN UTERINE EVACUATION PROCEDURES AT JINJA REGIONAL REFERRAL HOSPITAL
REFNo: HS5960ES

1. To assess the effectiveness of intravenous pethidine versus intravenous tramadol for perioperative analgesia in uterine evacuation procedure at Jinja Regional Referral Hospital
2. To compare the secondary outcomes encountered among women administered with intravenous pethidine versus those with Intravenous Tramadol for perioperative analgesia in uterine evacuation procedures at Jinja Regional Referral Hospital
3. To compare the level of patient satisfaction with intravenous pethidine versus Intravenous tramadol in uterine evacuation procedures at Jinja Regional Referral Hospital

 Somalia 2025-04-30 7:27:21 2028-04-30 Medical and Health Sciences Clinical Trial Degree Award
Lillian Wambuzi Ogwang
ID: UNCST-2021-R013189
 Evaluation of eye-tracking tests of affection and executive function among adolescents living with HIV in Kampala, Uganda version 3.0 dated 13 Mar 2025
REFNo: HS5920ES

1) to assess executive functioning and affect with three tests adapted to eye-tracking instrumentation
2) to correlate measures of eye-tracking with standardized mental health assessments

 Uganda 2025-04-30 17:55:08 2028-04-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Muriel Mac-Seing
ID: UNCST-2024-R005208
 The Together Project 2.0: Co-creation and co-evaluation of accessible and gender-sensitive sexual and reproductive health and rights education video series for and with youth in situations of vulnerability in Uganda and Bangladesh
REFNo: SS3812ES

1. To identify SRHR education gaps and needs for youth in situations of vulnerability with limited to no access to SRHR education programs, in Gulu, Uganda, and Dhaka, Bangladesh (Phase 1) 2. To co-develop with youth in situations of vulnerability inclusive SRHR education programs that are contextually adapted to their needs and realities, while considering accessibility, social acceptability, and available SRHR resources (Phase 2). 3. To co-evaluate the relevance of the co-developed SRHR education content and co-learn for improved adaptation through community feedback-seeking and to inform further dissemination strategies tailored to the specific needs and preferences of youth in Gulu, Uganda, and Dhaka, Bangladesh (Phase 3).
Canada 2025-04-30 17:51:45 2028-04-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
SSENYONJO  TADDEO BIRUNGI
ID: UNCST-2024-R002326
 EFFECT OF CLIMATE CHANGE ON THE SOCIO-ECONOMIC CONDITION OF SUBSISTENCE CATTLE FARMERS IN NAKASONGOLA DISTRICT,UGANDA.
REFNo: A593ES

1.3 Objectives of the Study 1.3.1 Major objective To examine the effects of climate change on the socio- economic condition of subsistence cattle farmers in Nakasongola district and propose an appropriate farmer adaptation strategy. 1.3.2 Specific objectives 1.To describe negative effects of climate change faced by subsistence cattle farmers in Nakasongola District. 2.To explore impact of climate change on the socio-economic conditions of subsistence cattle farmers in Nakasongola District. 3. To evaluate adaptation and coping practices of subsistence cattle farmers in Nakasongola District with the effects of climate change. 4.To develop an adaptation strategy to the effects of climate change relevant to subsistence cattle farmers in Nakasongola District.
Uganda 2025-04-30 17:47:19 2028-04-30 Agricultural Sciences Non-Clinical Trial Degree Award
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