Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Semanda Davis
ID: UNCST-2026-R024893
Management practices and infrastructure development of secondary schools in Uganda. A case of selected Adventist secondary schools in central region .
REFNo: SS5448ES

General Objective To examine the relationship between Management practices and infrastructure development in Adventist Secondary Schools in the Central Region of Uganda. Specific Objective i) To determine the relationship between Planning and infrastructure Development of SDA Secondary Schools in the central region of Uganda. ii) To assess the relationship between Coordination and infrastructure Development of secondary schools in the Central Region of Uganda. iii) To explore the relationship between monitoring and evaluation on the infrastructure Development of SDA Secondary Schools in Central Region of Uganda. iv) To Analyze the Moderating effect of SDA Church Policy on the infrastructure Development of SDA Secondary Schools in Central Region of Uganda.
Uganda 2026-07-16 19:14:14 2029-07-16 Social Science and Humanities Non-Clinical Trial Degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
Evaluation of MiniDock MTB for Decentralized Molecular Testing During Community-Based Active TB Case-Finding in Uganda
REFNo: HS8104ES

To estimate the incremental cost per TB case successfully initiated on treatment and the incremental cost-effectiveness of integrating MiniDock MTB� into community-based TB screening, compared with the standard of care, from a health system perspective.,To assess the feasibility, acceptability, and adoption of integrating MiniDock MTB� into community-based active TB case-finding from the perspectives of (a) participants undergoing testing and (b) healthcare providers implementing the intervention.,To determine whether integrating MiniDock MTB� near point-of-care molecular testing into community-based TB screening reduces the time from initial screening contact to TB treatment initiation, compared with the standard of care (centralized GeneXpert testing).,
Uganda 2026-07-16 17:26:06 2029-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JIMMY ADOKO
ID: UNCST-2025-R022752
RETENTION IN CARE AND ASSOCIATED FACTORS AMONG ADOLESCENTS RECEIVING ANTE-RETROVIRAL THERAPY (ART) IN SELECTED HEALTH FACILITIES IN ADJUMANI DISTRICT, UGANDA
REFNo: HS7420ES

1. To Identify socio-demographic factors associated with retention in care among adolescents on ART.
2. To Identify adolescent factors associated with retention in ART.
3. To Identify the community factors associated with adolescent retention on ART.
4. To Identify the health systems factors associated with retention in HIV care for adolescents on ART.
Uganda 2026-07-16 15:36:28 2029-07-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Makanika Vincent B
ID:
QUALITY OF SEXUAL HEALTHCARE AMONG PATIENTS WITH CHRONIC NON-COMMUNICABLE DISEASES IN RURAL WESTERN UGANDA: The Role of Sexual Emotional Competence in Patient Expectations, Satisfaction, and utilization of Sexual Healthcare.
REFNo: HS7903ES

General Objective
To assess how sexual emotional competence influences patient expectations, satisfaction, and utilization of sexual healthcare services.

Specific Objectives
1. To assess the levels and patterns of sexual emotional competence among patients with chronic non-communicable diseases in rural western Uganda.
2. To examine patients’ expectations regarding sexual healthcare services in rural western Uganda.
3. To determine patients’ levels of satisfaction with sexual healthcare services and perceived quality of sexual healthcare.
4. To examine the relationship between sexual emotional competence and patient expectations, satisfaction, and utilization of sexual healthcare services.
5. To assess whether patient expectations and satisfaction mediate the relationship between sexual emotional competence and utilization of sexual healthcare services.
6. To examine the influence of personal, clinical, and care-related characteristics on the relationships between sexual emotional competence, patient satisfaction, and utilization of sexual healthcare services.

Uganda 2026-07-16 15:05:17 2029-07-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Dumba Simon
ID: UNCST-2025-R019366
DIGITAL PLATFORMS’ INFLUENCE ON ENGLISH LANGUAGE TEACHER TRAINEES’ BIOGRAPHIES AND LINGUISTIC REPERTOIRES AT KYAMBOGO UNIVERSITY, UGANDA
REFNo: SS5256ES

Investigate how English language teacher trainees interact with their peers and mentors on digital platforms, focusing on the forms, frequency, and purpose of these interactions. 2. Identify specific ways in which digital platforms contribute to the development of English teacher trainees’ language biographies and linguistic repertoires through their academic and social engagements. 3. Assess the patterns of participation and types of engagement English language teacher trainees exhibit in online communities related to English language teaching. 4.Examine how regular engagement with digital platforms contributes to changes in teacher trainees’ linguistic identities and informs their evolving pedagogical approaches.
Uganda 2026-07-14 9:58:47 2029-07-14 Social Science and Humanities Non-Clinical Trial Degree Award
Ritah Ayebazibwe
ID: UNCST-2025-R018248
Prevalence and determinants of subclinical myocardial injury among people living with HIV and diabetes at the ISS clinic, Mbarara Regional Referral Hospital
REFNo: HS7521ES

1.To determine the prevalence of subclinical myocardial injury among people living with HIV and DM at ISS Clinic.

2.To determine the factors associated with subclinical myocardial injury among people living with HIV and diabetes at ISS Clinic.

3.To determine the correlation between glycemic control and Cardiac infarction Injury Score (CIIS) among PLWH and DM at ISS Clinic.

Uganda 2026-07-14 9:43:33 2029-07-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Immaculate Tumwebaze
ID:
The Impact of Climate Change on a Major Host-Parasite System (Bulinus-Schistosoma) across ecological gradients-disentangling global environmental changes and other factors
REFNo: NS1209ES

The proposed study will address three overarching questions:
1. How do intrinsic (genetics, hybridization, polyploidy) and extrinsic (climate, habitat) factors shape Bulinus diversity and host competence?
2. What are the evolutionary and ecological mechanisms underlying host-parasite adaptation in extreme environments?
3. How will climate-driven changes affect disease risk and transmission patterns across Africa and beyond?

Uganda 2026-07-14 9:41:38 2029-07-14 Natural Sciences Non-Clinical Trial Non-degree Award
Boaz Turyahikayo
ID: UNCST-2026-R024695
FACTORS AND BARRIERS TO MEASLES RUBELLA 2 UPTAKE AMONG CAREGIVERS OF CHILDREN 20-36 MONTHS IN ISINGIRO DISTRICT.
REFNo: HS8031ES

1. To estimate the prevalence of Measles Rubella 2 (MR2) vaccine uptake among children aged 20–36 months in Isingiro District. 2. To determine the association between caregiver knowledge, attitudes, accessibility to immunization services, trust in health services, socio-demographic characteristics, and uptake of MR2 vaccine among children aged 20–36 months in Isingiro District. 3. To explore caregiver, community, and health-system barriers influencing uptake of the Measles-Rubella 2 (MR2) vaccine among children aged 20–36 months in Isingiro District
Uganda 2026-07-14 9:40:16 2029-07-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Anacret Byamukama
ID: UNCST-2023-R007193
Prevalence and correlates of pulmonary hypertension among people with HIV in Uganda
REFNo: HS7889ES

Aim 1: To characterize the prevalence and clinical correlates of pulmonary hypertension among people with HIV compared to those without HIV in Uganda. Aim 2: To evaluate the relationship between biomarkers of inflammation and endothelial dysfunction by HIV serostatus and assess whether these biomarkers correlate with pHTN in Uganda.
Uganda 2026-07-14 10:26:03 2029-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SAMUEL JJUNJU
ID: UNCST-2023-R006269
Pneumocystis Pneumonia Among Adults with Advanced HIV Disease Diagnosed with Pulmonary Syndrome In South Western Uganda. A Prospective Observational Cohort Study
REFNo: HS7796ES

I.To determine the prevalence of Pneumocystis pneumonia among adults with advanced HIV disease presenting with pulmonary syndrome at Mbarara Regional Referral Hospital. II.To evaluate the diagnostic performance of serum ?-D-glucan and oropharyngeal PCR for detection of Pneumocystis jirovecii among adults with advanced HIV disease presenting with pulmonary syndrome at Mbarara Regional Referral Hospital. III.To determine the in-hospital outcomes among adults with AHD presenting with pulmonary syndrome at Mbarara Regional Referral Hospital. IV.To determine the 30-day post hospital discharge mortality among adults with AHD presenting with pulmonary syndrome at Mbarara Regional Referral Hospital. V.To determine the baseline predictors of mortality among adults with AHD presenting with pulmonary syndrome at Mbarara Regional Referral Hospital.
Uganda 2026-07-14 10:21:26 2029-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Passy Claire Wood
ID: UNCST-2025-R023226
Social Protection Programming and Refugee Girls' Transition to Secondary Education in Uganda: Barriers and Opportunities.
REFNo: SS5423ES

1.To understand the day-to-day experiences of refugee girls during the transition from Primary school to secondary school. 2.To examine what household and community support is available to these refugee girls and how they experience its adequacy during the transition from primary to secondary school. 3.To analyse the perceptions of these refugee girls on their family’s use of cash transfers in supporting their school needs. 4.To explore what forms of support these refugee girls consider necessary for successful and safe transitions from primary to secondary school.
Uganda 2026-07-14 10:16:18 2029-07-14 Social Science and Humanities Non-Clinical Trial Degree Award
Marianna Agaba Nyangire
ID:
Work-Related Musculoskeletal Disorder prevention among manufacturing workers in Kampala Industrial Park and Business Park, Namanve-Uganda: prevalence, safe practices, and the effect of participatory toolbox talks
REFNo: HS7589ES

Overall aim
To assess the prevalence and factors associated with Work-Related Musculoskeletal Disorders (WRMSDs), identify participatory toolbox talk components, and evaluate their effectiveness among manufacturing workers in Kampala Industrial and Business Park, Namanve-Uganda.
4.2.2 Sub-studies
1. To estimate the prevalence of Work-Related Musculoskeletal Disorders (WRMSDs) and determine their associated factors among manufacturing workers within Kampala Industrial and Business Park, Namanve-Uganda.
2. To explore factors influencing safety practices related to WRMSDs of manufacturing workers within Kampala Industrial and Business Park, Namanve, Uganda.
3. To identify contextually appropriate components and delivery strategies for participatory toolbox talks that prevent WRMSDs among manufacturing workers in Kampala Industrial and Business Park, Namanve-Uganda.
4. To evaluate the effect of participatory toolbox talks on the occurrence of WRMSDs among manufacturing workers in Kampala Industrial and Business Park, Namanve-Uganda.

Uganda 2026-07-14 10:12:12 2029-07-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Johnes Obungoloch
ID: UNCST-2024-R005331
Evaluation of the Functionality of the Lab-Built Halbach Array MRI System at Mbarara University of Science and Technology
REFNo: HS8105ES

The overall aim of this study is to benchmark the image quality of the open-source low-field MRI system constructed at the MRI-Uganda lab of MUST1 with the identical system constructed at the LUMC.

specific Objectives

i.To acquire T1 and T2 weighted limb and brain images of adult volunteers using the low-field MRI system at the MUST lab, and the 1.5T MRI at Mbarara Regional Referral Hospital.

ii.To evaluate signal-to-noise ratio (SNR), contrast to noise ratio (CNR), image resolution, and accuracy of the anatomical structures shown.
Uganda 2026-07-14 10:01:45 2029-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julia Dickson-Gomez
ID: UNCST-2019-R000775
Substance Use and Harm Reduction Needs among Urban Refugees in Kampala, Uganda
REFNo: HS7826ES

The objective of the proposed research is to explore substance use among refugees in Kampala and their access to drug treatment and harm reduction services.
Specific objectives
Specific objectives of the proposed research are:
1. To explore patterns of substance use among refugees in Kampala including kinds of substances used, reasons for use and the social, legal and health consequences of substance use. (Questions 1-3)
2. To explore the services available to refugees to stop or reduce substance use or harms associated with substance use. (Questions 4 and 5).


USA 2026-07-13 18:43:13 2029-07-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FAITH  AHABYOONA MUGISHA
ID: UNCST-2025-R019772
Effect of Climate-Smart Financing on Market-Driven Coffee Production in Uganda
REFNo: SS4866ES

General Objective: To examine the effect of climate-smart financing on market-driven coffee production in Uganda. Specific Objectives: 1. To assess the effect of financing coffee nurseries on market-driven coffee production. 2. To investigate the effect of farm rejuvenation financing on market-driven coffee production. 3. To examine the effect of financing Coffee Washing Stations on coffee competitiveness and quality.
Uganda 2026-07-13 18:37:25 2029-07-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ying Su
ID: UNCST-2026-R024567
Experiences of Lay Counsellors in Addressing Stigma During Group Support Psychotherapy and Its Relationship with Suicidal Behaviour among Depressed Persons Living with HIV in Uganda: A Mixed Methods Study
REFNo: HS7630ES

To address these gaps, this study adopts a mixed-methods, mechanism
focused design that integrates qualitative insights from lay counsellors
with secondary quantitative analysis of trial data.
Specifically, the study aims to:
i)
Explore how lay counsellors working in community settings in
Uganda understand, experience, and address stigma among their
clients, and to identify the psychosocial, relational, and practical
mechanisms through which their support facilitates coping,
engagement in care, and recovery.
ii)
iii)
Examine the baseline association between HIV-related stigma
and suicidality—operationalised as suicidal ideation and history
of previous suicide attempt—among depressed people living with
HIV.
Determine whether Group Support Psychotherapy reduces
suicidal ideation over time, particularly at 2 months (during
therapy) and 6 months (post-therapy), compared with the control
condition.
China 2026-07-13 11:34:56 2029-07-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dorcas Adongo
ID: UNCST-2025-R023015
FACTORS ASSOCIATED WITH ACCESSIBILITY OF FAMILY PLANNING SERVICES AMONG PERSONS WITH DISABILITIES IN LIRA CITY
REFNo: SS4906ES

General objective To examine the factors associated with accessibility of family planning services among persons with disabilities in Lira City. Specific Objectives 1.To assess the level of access to family planning services among PWDs. 2.To assess the sociodemographic factors associated with the level of accessibility of family planning services among PWDs. 3.To investigate disability-related factors associated with accessibility of family planning services. 4.To explore health system factors associated with accessibility of family planning services among PWDs.
Uganda 2026-07-13 11:30:01 2029-07-13 Social Science and Humanities Non-Clinical Trial Degree Award
Fred  Okuku Machyo
ID:
EVALUATING THE INTEGRATION OF PEGFILGRASTIM FOR THE MANAGEMENT OF CHEMOTHERAPY-INDUCED FEBRILE NEUTROPENIA AT THE UGANDA CANCER INSTITUTE
REFNo: HS8034ES

1. To assess the feasibility and uptake of pegfilgrastim prophylaxis among eligible adult chemotherapy patients at UCI, including reach, fidelity, and vial utilization patterns.
2. To compare clinical outcomes, specifically FN incidence, infection-related hospitalizations, and chemotherapy dose delays or reductions, between pegfilgrastim recipients and historical cohorts managed without routine G-CSF prophylaxis.
3. To document baseline filgrastim prescribing patterns, dosing practices, and associated clinical outcomes prior to pegfilgrastim integration.
4. To evaluate healthcare workers’ knowledge, attitudes, and perceptions regarding FN prevention and the comparative use of pegfilgrastim versus filgrastim.
5. To identify system-level, provider-level, and process-level barriers and facilitators influencing pegfilgrastim implementation and long-term sustainability within UCI.

Uganda 2026-07-09 19:40:59 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joan Busingye
ID: UNCST-2026-R026289
COGNITIVE BEHAVIORAL INTERVENTIONS AND PATIENT RECOVERY AMONG INDIVIDUALS WITH MENTAL ILLNESS. A CASE OF SELECTED HOSPITALS IN CENTRAL UGANDA
REFNo: SS5507ES

1. To determine the influence of cognitive interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
2. To assess the effect of emotional interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
3. To examine the influence of behavioral interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
4. To evaluate the moderating effect of patient-related factors (age, gender, diagnosis, duration of illness, treatment adherence, and cultural beliefs) on the relationship between cognitive behavioral interventions and patient recovery in selected hospitals in Central Uganda.

Uganda 2026-07-09 19:38:45 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
Development of a Rapid Fieldable Nanopore Sequencing-based Prognostic and Diagnostic Assay to Advance Clinical Management Decision-Making
REFNo: HS7987ES

- Verify harmonized sample preparation workflow from archived biospecimens for the integrated pathogen diagnostic and host-response assay that is run on the INSPIRE device - Verify functionality of integrated software and hardware required for the INSPIRE device on archived biospecimens
Uganda 2026-07-09 19:37:11 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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