Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Amon Kanyesigye
ID:
KNOWLEDGE OF SICKLE CELL DISEASE AND ASSOCIATED FACTORS AMONG UNDERGRADUATE STUDENTS AT MAKERERE UNIVERSITY
REFNo: HS2823ES

1.To determine knowledge and awareness levels of SCD among undergraduate students at
Makerere University.
2. To determine the factors associated with knowledge and awareness levels of SCD among
undergraduate students at Makerere University.
Uganda 2023-05-18 16:00:11 2026-05-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Yume Nomoto
ID:
A comparison of nutritional status among children under five years of age between refugee and host communities: A multi-sectoral cross-sectional study in Lamwo district, Uganda
REFNo: SS1640ES

To estimate determinants of nutritional status among children in refugee and host communities,To estimate the difference in the prevalence of malnutrition among children between refugee and host communities,To estimate the difference in nutritional status among children 0-59 months of age between refugee and host communities.,
Japan 2023-05-18 15:50:51 2026-05-18 Social Science and Humanities Non-Clinical Trial Degree Award
Patrick Tumwine
ID:
An Exploration of How Education Stakeholders Perceive the Implication of Grade Repetition at a Secondary School Level in Western Uganda. A Qualitative Multiple-Case Study.
REFNo: SS1727ES

To establish the parents' and administrators' perceptions about the cost implications of grade repetition within the secondary education system in Western Uganda.

To describe the teachers' and administrators' perception of the current grade repetition system's impact on students' self-efficacy.

To establish the understanding of administrators and chairpersons of PTA on the impact of grade repetition on national examination pass rates and related social promotion policy implications.
Uganda 2023-05-18 15:49:44 2026-05-18 Social Science and Humanities Non-Clinical Trial Degree Award
franck Sikakulya
ID: UNCST-2021-R013687
Effectiveness of movement and respiratory rate monitoring device in early detection of vital sign deterioration and hospitalisation outcomes among patients admitted at Kitovu Hospital in Central Uganda
REFNo: HS2792ES

To determine the effectiveness of a non-invasive movement and respiratory rate monitoring device in predicting the outcome of medical patients admitted to Kitovu Hospital. To assess the effectiveness of a non-invasive movement and respiratory rate monitoring device in early detection of vital sign deterioration among patients admitted at Kitovu Hospital.
Democratic Republic of Congo 2023-05-18 15:45:26 2026-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JENNIFER WILBURN
ID:
AMR STEWARDSHIP KNOWLEDGE, PERCEPTIONS AND PRACTICES AMONG DISPENSERS IN COMMUNITY DISPENSARY SETTINGS IN KAWEMPE, KAMPALA
REFNo: SS1814ES

1. Evaluate the level of knowledge of antimicrobial resistance and antimicrobial stewardship of individuals working and dispensing antimicrobials within public and private community settings where antibiotics are dispensed.

2. Gain an understanding into perceptions toward AMS of individuals working and dispensing antimicrobials within these settings.

3. Document self-reported practices towards AMS of individuals working and dispensing antimicrobials within these community dispensary settings.
UK 2023-05-18 15:43:17 2026-05-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ali Ssetaala
ID: UNCST-2021-R011817
Multi-site study for Adolescent Girls and Young Women for future HIV vaccines and antibodies candidates for prevention (MAGY).
REFNo: HS2741ES

Aim 1: To investigate factors that influence the design and participation in
clinical trials of future HIV vaccine and bnAb product candidates for AGYW.
Aim 1.1. To understand AGYW, parent/guardians, community members
perspectives on the inclusion of AGYW in future trials to develop and test HIV
vaccine candidates and broadly neutralizing antibodies (bnAb) products.
Aim 1.2. To understand the factors that influence the perceptions (e.g., vaccine
confidence vs hesitancy) of future HIV vaccine and bnAb products among AGYW,
parents/guardians and community members.
Aim 2: Establish AGYW clinical trial preparedness cohorts for the evaluation
of enhanced broadly neutralizing antibodies as a long-acting injectable HIV
prevention product.
Aim 2.1. To establish cohorts of AGYW aged 15-24 years in eastern and southern
Africa using best practices for standard of care, child protection and linkage to
sexual reproductive health (SRH) and HIV services and care.
Aim 2.2. To understand HIV risk and incidence among AGYW aged 15-24 years to
support the calculation of a background HIV incidence counterfactual.
Aim 3: To characterize peripheral immune cells via the least invasive
sampling approaches for assessment or prediction of the suitability of HIV
vaccine candidates for AGYW.
Aim 3.1. To assess the feasibility and acceptability of different sampling techniques
for AGYW
Aim 3.2a. To assess or predict the suitability of HIV vaccine candidates for AGYW
ages 18+ years by characterizing peripheral blood samples and performing
immunological comparison to adults.
Aim 3.2b. To assess or predict the suitability of HIV vaccine candidates for AGYW
ages 15-17 years by characterizing peripheral blood samples and performing
immunological comparison to older adolescents and adults.
Aim 3.3. Examine the temporal relationships between immunological and microbial
factors associated with HIV susceptibility in the female genital tract of AGYW.


Uganda 2023-05-18 15:31:35 2026-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anna Nordén
ID:
Social Acceptance of a green Transition in East Africa
REFNo: SS1666ES

Civil servants and policy makers working with environmental related policies and policy instruments in East Africa.,Enhancing Evironmental related policies and policy instruments in East Africa.,
Sweden 2023-05-18 15:05:28 2026-05-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannington Businge
ID: UNCST-2022-R009477
Board Characteristics, Strategic Orientation and performance of Insurance Companies in Uganda UCUREC-2022-392
REFNo: SS1546ES

To examine the influence of strategic orientation on the relationship between board characteristics and performance of Insurance companies in Uganda.,To determine the influence of board characteristics on performance of Insurance companies in Uganda.,To establish the board practices of Insurance companies in Uganda.,The overall objective of the study will be to determine the influence of strategic orientation on the relationship between board characteristics, and performance of Insurance Companies in Uganda. ,
Uganda 2023-05-18 15:00:59 2026-05-18 Social Science and Humanities Non-Clinical Trial Degree Award
Michael Mukiibi
ID:
Effectiveness of a Smartphone Application on the Accessibility to Information on Maternal, Newborn, and Child Health Care in Slum Settlements in Uganda
REFNo: HS2818ES

i To investigate whether, and how, a smartphone-based job aid used by CHWs improves women’s uptake of facility-based delivery and other maternal health services in Uganda. ii To establish the accessibility of infant and maternal healthcare information by New born and Child health care uptake of facility-based delivery and other maternal health services in Uganda iii To develop a mobile smartphone application to address the accessibility to the information on Maternal, Newborn, And Child Health Care in Slum Settlements in Uganda iv To pilot-test the application in the study area
Uganda 2023-05-11 15:03:31 2026-05-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Maxensia owor
ID: UNCST-2021-R014003
Metabolic Impact of Dolutegravir based ART in Postpartum Women Living with HIV and their Infants” (MI-DART study)
REFNo: HS2809ES

Aim 1: To determine the impact of maternal HIV and DTG-ART on i) energy intake and expenditure, ii) metabolic profile and iii) body composition and weight in postpartum women.
Aim 2: To determine the impact of maternal HIV and DTG-ART on i) energy intake and expenditure, ii) metabolic profile and iii) body composition and growth of their HEU infants.

Uganda 2023-05-11 15:01:13 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Russell Michael
ID:
Fire and Climate in the Rwenzori Mountain National Park
REFNo: NS531ES

To develop a long-term record of fire in high-elevation areas of the Rwenzori Mountain National Park. With this record, we will investigate the relationship between fire and climate change through time. Our ultimate objective is to determine whether changes in air temperature cause changes in fire frequency through time. This will allow us to better predict changes in fire regime in the future.
USA 2023-05-11 15:00:00 2026-05-11 Natural Sciences Non-Clinical Trial Non-degree Award
George Kipaalu Bogere
ID:
Internal Audit Function and Public Funds Management in Uganda. A case of selected Local Governments in Busoga sub Region.
REFNo: SS1708ES

1. To establish the relationship of Internal Audit function and Internal Control System Evaluation in Uganda. A case of selected Local Governments of Busoga.
2. To determine the effect of Internal Control System Evaluation on Auditor Independency and Integrity in Uganda. A case of selected Local Governments of Busoga.
3. To evaluate the Correlation between Audit independency and integrity and public funds management in Uganda. A case of selected Local Governments of Busoga.
4. To establish the association between internal Audit function and public funds management in Uganda. A case of selected Local Governments of Busoga.

Uganda 2023-05-11 14:59:17 2026-05-11 Social Science and Humanities Non-Clinical Trial Degree Award
MARBLE NASASIRA
ID: UNCST-2021-R012753
INCIDENCE AND PREDICTORS OF QTC PROLONGATION AMONG DRUG RESISTANT TUBERCULOSIS PATIENTS RECEIVING BEDAQUILINE BASED REGIMEN IN UGANDA.
REFNo: HS2802ES

To develop and validate a clinical risk score To estimate the risk of QTc prolongation after initiation of BDQ-containing regimens among DR-TB patients,To determine the predictors of QTc prolongation among patients receiving drug resistant tuberculosis treatment in Uganda,To assess the incidence of QTc prolongation among patients receiving drug resistant tuberculosis treatment in Uganda.,To determine the incidence, factors associated with QTc prolongation, develop and validate risk score among patients receiving BDQ based regimen. ,
Uganda 2023-05-11 14:57:53 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
Phase B SAPPHIRE
REFNo: HS2784ES

Reduce HIV incidence using innovative strategies for HIV prevention and
treatment to simultaneously reach persistent driver populations.

Uganda 2023-05-11 14:55:58 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adalbert Aineomucunguzi
ID:
Conservation Research to monitor Grey Crowned Cranes in Uganda
REFNo: NS518ES

1. Understand movement, long-term survival and landscape use of the Grey Crowned Cranes.
2. Provide data on Grey Crowned Crane populations and their distribution in Uganda
3. Advance our understanding of landscape use (particularly agriculture) and its influence on size and distribution of crane populations
4. Identify areas where the potential exists for crane conservation interventions

Uganda 2023-05-11 14:53:15 2026-05-11 Natural Sciences Non-Clinical Trial Non-degree Award
Ali Ssetaala
ID: UNCST-2021-R011817
CHILI- Adaptation
REFNo: HS2758ES

To support development of a new screening test for Cervical Cancer detecting high risk HPV DNA phenotypes and cancer proteins biomarkers in low-income countries.

Specific Objectives
1. To collect and analyze self-samples
2. To identify high risk HPV DNA in the self-samples
3. To link the levels of proteins measured in the self-samples with the cervical cancer lessions detected by papsmear and VIA.
4. To evaluate the effect of confounding factors on the cervical cancer protein levels in the self-samples

2.To understand user’s perspectives regarding (self-) sampling

Uganda 2023-05-11 14:52:00 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simon Kigozi Peter
ID: UNCST-2022-R009813
Studying Incidence of Malaria from Routine Health Facility Reporting to Assess Impact of Targeted Control Interventions: Transforming Surveillance for Malaria Control
REFNo: HS2783ES

4. Investigate the level of residual burden of malaria missed by routine surveillance using randomised surveys.,3. Estimate the impact of targeted control intervention on incidence of malaria within health-facility-catchments.,2. Describe population spatial access to routinely reporting health facilities and estimate health facility catchments.,1. Evaluate the quality of routine HMIS data generated through the national surveillance system (DHIS-2) against facility register records.,To investigate the effectiveness of HMIS-based incidence in assessing the impact of targeted control interventions on malaria burden, through the following objectives.,
Uganda 2023-05-11 14:50:40 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arthur  Mpimbaza
ID: UNCST-2022-R008866
Malaria rapid diagnostic test (RDT) capture and reporting assessment (MaCRA): Uganda protocol
REFNo: HS2747ES

Primary
1. Measure agreement between HCW and panel RDT results in Uganda.
Secondary
2. Measure the association between key characteristics of HCWs, RDT guidelines, health systems, malaria epidemiology and patient demographics and type of agreement/disagreement between the HCW and panel RDT results.
3. Understand how characteristics of HCWs, RDT guidelines, health systems, malaria epidemiology, and patient demographics affect the ability of HCWs to accurately implement, interpret, use, record and report RDT results.
4. Assess the fidelity of data entry from health facility registers to the health management information system (HMIS).
5. Determine the degree of over- and under- treatment for malaria and associations with characteristics of HCWs, RDT guidelines, health systems, malaria epidemiology and patient demographics.
6. Determine whether there is an observer impact of the study on monthly test positivity rates (TPRs).
7. Develop a database of photos of results from various RDT brands that can be used to train an artificial intelligence application to automate the interpretation and reporting of RDTs.
8. Classify common unusual RDT results that appear in RDT photos and assess patterns of errors to guide NMP and PMI on issues related to RDT administration and case management practices.
9. Calculate the accuracy of HealthPulse (Audere, Seattle, WA), a smartphone-based application that uses artificial intelligence to interpret RDT results, compared to the panel RDT results after training on a random selection of RDT photographs.
10. Compare agreement of RDT results read at one week and one month after administration with the initial read to determine the durability of RDT results over time.

Uganda 2023-05-11 14:45:16 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dominik Biesalski
ID:
The Drivers, Effects and Measurement of Time Use Among the Urban Poor: Evidence from Uganda
REFNo: SS1674ES

Get insights into the time use patterns of urban workers and understand their effects on productivity and well-being.
Germany 2023-05-11 14:41:00 2026-05-11 Social Science and Humanities Clinical Trial Degree Award
Anthony  Batte
ID: UNCST-2022-R011127
Malaria Associated Pathogenesis of Chronic Kidney Disease (MAP-CKD) Study
REFNo: HS2794ES

To define the impact of AKI and persistent kidney disease on morbidity, mortality, and health-related quality of life. ,To define host pathways associated with maladaptive kidney repair following severe malaria associated AKI. To determine risk factors for short-term and long-term kidney disease following severe malaria,
Uganda 2023-05-11 14:33:58 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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