Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Esther Bibangambah Mulungi Nabatanzi
ID: UNCST-2024-R004669
 Health Related Quality of Life of children with Cerebral Palsy in Wakiso District: An Explorative interventional study
REFNo: HS4516ES

4. Evaluate the impact of both hospital-based and community-based early intervention program on Health-Related Quality of Life of children with Cerebral Palsy and the depression anxiety and stress level of their primary caregivers. ,3. Define the depression, anxiety and stress of primary caregivers of children with Cerebral Palsy in Wakiso, Uganda,2. Define the Health-Related Quality of Life of children with CP in Wakiso, Uganda,1. Define the epidemiology of Cerebral Palsy in Wakiso, Uganda,We aim to establish a cohort of children with CP in the Wakiso district of Uganda to define the epidemiology of CP, describe the HRQoL of the children with CP and depression, anxiety and stress level their primary caregivers to evaluate the impact of any community-based early intervention. ,
 Uganda 2024-08-28 18:51:55 2027-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ACEN CATHERINE BOKELLO
ID: UNCST-2024-R004924
 Internal Control Systems and Public Financial Management in Selected Local Governments in Uganda
REFNo: SS2809ES

To determine the significant relationship between monitoring and public financial management in selected local governments in Uganda.,To establish the influence of communication on public financial management in selected local governments in Uganda,To establish the effect of control activities on public financial management in selected local governments in Uganda,To establish the influence of risk assessment on public financial management in selected local governments in Uganda.,To determine the effects of control environment on public financial management in selected local governments in Uganda,To assess the effects of internal control systems on public financial management in selected Local Governments, in Uganda.,
 Uganda 2024-08-28 18:49:02 2027-08-28 Social Science and Humanities Non-Clinical Trial Degree Award
Beatrice Kyasiimire
ID:
Living near Uganda’s Queen Elizabeth National Park; evaluating alternative livelihood initiatives
REFNo: NS830ES

Assess communities\' governance structures and systems\' impacts on alternative livelihoods around the park.,Assess community and external actors\' perceptions of the enabling conditions for alternative livelihood projects around the park.,Evaluate the enabling conditions for alternative livelihood projects in communities around Queen Elizabeth National Park.,The overall aim of this study is to understand the enabling conditions influencing the implementation and effectiveness of alternative livelihoods around Queen Elizabeth National Park. ,
 Uganda 2024-08-28 18:46:54 2027-08-28 Natural Sciences Non-Clinical Trial Degree Award
SHAFIGA BABIRYE
ID: UNCST-2024-R004302
 LEVEL AND PREDICTORS OF CATASTROPHIC HEALTH EXPENDITURE AMONG RECIPIENTS OF AMBULATORY SURGICAL SERVICES AT KYABIRWA SURGICAL CENTER
REFNo: SS2900ES

To establish the intra-household predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To analyze the clinical predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To assess the intrapersonal predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To determine the prevalence of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To assess the level and predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,
 Uganda 2024-08-28 18:41:10 2027-08-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
 Exploring the Nexus of Clean Water Access and Sexual Reproductive Health among Women and Girls in Rural Uganda
REFNo: SS2829ES

1. How do socio-cultural contexts, such as traditional gender roles and community expectations, shape the challenges women and girls face when accessing clean water?
2. How do power dynamics influence the management, utilization, and involvement of women in activities related to water access?
3. What role does education play on the awareness and implementation of Sexual Reproductive Health practices among women and girls?

Uganda 2024-08-28 18:39:31 2027-08-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hadijah Yahyah
ID:
Assessing the Environmental Sustainability Implications of Farm-Level Persistent Organic Pollutant Pesticide Use in Uganda
REFNo: SS2683ES

1. To examine the pathways for the transmission of POPs pesticides into Mukono District;
2. To evaluate the trends and characteristics of farm level use of POP pesticides into Mukono District;
3. To assess the role and level of knowledge, attitudes and practices of farmers in decision making for POPs pesticide use in Mukono District;
4. To assess the adequacy of the existing structures , tools, and approaches for the regulation of importation and farm-level use of POP pesticides in Uganda;

 Uganda 2024-08-28 18:31:37 2027-08-28 Social Science and Humanities Non-Clinical Trial Degree Award
Catherine Nakaye
ID: UNCST-2021-R013222
 FEASIBILITY, ACCEPTABILITY, AND PERSISTENCE OF COMMUNITY DRUG SHOP-BASED HIV SELF-TESTING AND ORAL PREP DELIVERY AMONG FEMALE SEX WORKERS IN KITEBI, KAMPALA CAPITAL CITY, CENTRAL UGANDA (DROP-D).
REFNo: HS4556ES

Examine FSW and community drug shop PrEP providers’ experiences, preferences, barriers, and facilitators related to the community drug shop based HIVST and oral PrEP delivery model,Assess persistence of community drug shop-based HIVST and oral PrEP delivery among FSW in Kampala,Assess the feasibility and acceptability of utilising community drug shops to offer HIVST and oral PrEP delivery among FSW in Kampala,
 Uganda 2024-08-28 18:28:21 2027-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Semyalo Paul Ddumba
ID: UNCST-2021-R012585
 RISING INEQUALITIES OCCASIONED BY COVID-19 IMPACTS IN URBAN INFORMAL SETTLEMENT IN UGANDA (CASE STUDY OF ACCESS AND USE OF SAFE WATER IN KAMPALA SLUM AREAS)
REFNo: NS746ES

To assess microbiological and physicochemical water quality both at the source and household reserves, as well as carryout sanitation risk assessment of the different water sources in Kisenyi.,To assess the patterns of access to and utilization of safe water among households in Kisenyi, Central Division, examining the changes that occurred before, during, and after the COVID-19 pandemic.,To investigate the diverse socio-economic determinants of households in Kisenyi which influences their choice of water source and how this was impacted by COVID-19.,Examine the multifaceted impact of the COVID-19 pandemic on the exacerbation of social and economic inequalities among the urban poor, with a specific focus on access to Water, Sanitation, and Hygiene (WASH) services, as a means to gain insights and inform strategies for addressing these disparities.,
 Uganda 2024-08-28 18:19:09 2027-08-28 Natural Sciences Non-Clinical Trial Non-degree Award
ERINAH MUDONDO -
ID:
Liquidity management practices and Financial performance of banking institution in Kampala metropolitan - Uganda
REFNo: SS2872ES

To establish the influence of liquidity risk on the financial performance of banking institutions in Kampala Metropolitan.,To investigate the influence of liquidity management practices on financial performance of banking institutions in Kampala Metropolitan, Uganda.,
 Uganda 2024-08-28 18:17:15 2027-08-28 Social Science and Humanities Non-Clinical Trial Degree Award
Robert Downing George
ID: UNCST-2020-R014615
 A prospective, multi-centre study to evaluate the diagnostic sensitivity and specificity of the Determine Syphilis Advanced test.
REFNo: HS4648ES


The primary objective of this study is:
• To determine the diagnostic sensitivity and specificity of the Determine Syphilis Advanced test results using fingerstick capillary whole blood, venous whole blood, serum and venous plasma, when the test is performed by professional users.

The reference test will be Elecsys® Syphilis test (Roche). This test is an electrochemiluminescence immunoassay for the qualitative determination of total antibodies against Treponema pallidum. Samples with a negative Elecsys Syphilis result will be considered reference test-negative. Samples with a positive Elecsys Syphilis result will be confirmed by Treponema Pallidum Particle Agglutination (TPPA) testing. The TPPA result must be positive for the sample to be considered reference test-positive. Samples with a positive Elecsys Syphilis result but a negative or indeterminate TPPA result will be considered indeterminate and excluded from the study analyses. Potential discrepant result resolution using the Abbott Architect i1000SR Syphilis chemiluminescent microparticle immunoassay may be conducted for study reference test-positive or reference test-negative samples with discrepant investigational test results. The results from potential discrepant result resolution testing will be presented as table footnotes only. In addition to these treponemal tests, non-treponemal RPR testing will also be conducted for the reference test-positive participants, and the results may be stratified also by RPR status. All discrepant specimens shall be repeated using the same lot of RDT, and then on all available lots and any variability noted.

Another primary study objective is to compare the performance of the Determine Syphilis Advanced test with two commercially available similar tests, to meet the regulatory requirements in Japan. These two commercially available tests will be the TPPA test (SERODIA-TPPA, Fujirebio, Japan) and the Determine Syphilis TP test (Abbott). This analysis will be performed using 60 reference test-positive samples and 60 reference test-negative samples. The testing will be performed using plasma.

One study secondary objective is to evaluate the usability through completion of a user experience questionnaire (healthcare and laboratory staff).

Another study secondary objective is to determine the stability of venous whole blood, serum and plasma samples for use with Determine Syphilis Advanced, after refrigeration of the venous whole blood, serum and plasma at 2-8 degrees Celsius during 7 days before testing.

 UK 2024-08-28 17:34:38 2027-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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