Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
MICHAEL KAWOOYA GRACE
ID: UNCST-2020-R014672
Machine Learning-based Algorithm for Automatic Screening of Pulmonary Tuberculosis using Chest X-rays in the Ugandan Population
REFNo: HS2043ES

1. Create an open, labelled, inclusive dataset for CXR images and clinical information collected from the Ugandan population. 2. Develop machine learning models for automatic recognition of TB features in CXR images. 3. Integrate the developed models in a decision support web application. 4. Validate the developed system in a clinical study.
Uganda 2022-09-20 12:45:22 2025-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Guillaume DESOUBEAUX V
ID:
microMONKEY A model of international translational study to address the prevention of fungal infection in African great apes based on the One Health concept
REFNo: NS420ES

This study aims to better depict the epidemiology of microsporidiosis, to demonstrate the impact that the close proximity of humans to animals can have on the microbiological digestive carriage in great apes, and to understand its ecological consequences, in terms of their zoonotic potential. Preventive means to better control inter-species microbial transmission could thus be proposed. This project is totally part of the current international trend to preserve the environment and defend the animal welfare, supported by the One Health program.
France 2022-09-20 12:43:17 2025-09-20 Natural Sciences Non-Clinical Trial Non-degree Award
Mucunguzi Atukunda
ID:
Feasibility and acceptability of patient clubs as Intervention to improve anti-hypertensive drug stocks for Adults Living with HIV and Hypertension in Uganda – A mixed methods study
REFNo: SS1438ES

To evaluate facilitators and barriers for participation and non-participation in patient clubs among patient with HIV infected patients with hypertension. To determine the proportion of patients participating in the patient clubs that have achieved blood pressure control. To determine the number of patients with Hypertension and HIV who are participating in the patient clubs that have adequate anti-hypertension medications at every clinic visit
Uganda 2022-09-16 9:48:55 2025-09-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Wang Vibeke
ID:
Breaking BAD: Understanding the Backlash Against Democracy in Africa-Uganda case
REFNo: SS1351ES

The overall objective of this project is to analyze the processes of political and economic development in Africa. It focuses on the obstacles and potentials of democratic consolidation on the continent since the transition to market economics and multiparty rule
Norway 2022-09-16 9:46:21 2025-09-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Godfrey Zari Rukundo Zari
ID: UNCST-2019-R001500
Burden of neuro-cognitive disorders and associated factors in persons aged 50 years or older with a history of Traumatic Brain Injury in Southwestern Uganda
REFNo: HS2257ES

General objective
To determine the burden of neurocognitive disorders and associated factors in patients with a history of Traumatic Brain Injury (TBI) in selected communities of southwestern Uganda.

Specific objectives
1. To determine the prevalence of neurocognitive disorders in patients with a history of TBI in selected communities in south-western Uganda.
2. To determine the factors associated with the development of neurocognitive disorders in patients with a history of TBI in selected communities in south-western Uganda.

Uganda 2022-09-16 12:17:44 2025-09-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Yusuf Byaruhanga Byenkya
ID:
Locally-driven co-development of plant-based value chains towards more sustainable African food system with healthier diets and export potential (InnoFoodAfrica)
REFNo: SS1422ES

Main Objective
1. InnoFoodAfrica aims to develop new sustainable value chains (VC) to produce and distribute diverse and healthy foods from African farms to local and export markets.
Specific Objectives
1. Develop resource-efficient, safe and sustainable food production VCs by empowering small-holder farmers, processors, producers and consumers via co-creation process with African and European experts,
2. Catalyzing new local and international business and market opportunities in the cereal-pulse-root crop-fruit food and packaging VCs by engaging VC actors and investigating new business models.
3. Adapt and implement dietary guidelines that are based on cereal-pulse-root crop-fruit-based foods and diets tackling malnutrition of small children (focusing also on the health of expecting and breast-feeding mothers who are responsible for taking care of themselves and their children within the first 1000 days of life) and adults under the risk of obesity.
4. Diversify of plant-based agrofood systems enabling nature-benefiting farming and production of African food, which form a basis for a balanced diet.
5. Develop safe and nutrient-dense cereal-pulse-root crop-fruit-based food ingredients and products which tackle malnutrition from two angles: nutrient deficiencies and obesity, taken into account both children (<1000 days) and adult consumer segments.
6. Increase resource-efficiency of the African cereal-pulse-root crop-fruit-based food VCs by reducing food loss and food waste by improved post-harvesting and storage practices, and by creating value from side streams via bio-based packaging solutions for replacement of plastic.
7. Establish a pan-African food R&D&I (research, development and innovation) community via cooperation and creation of an open Innovation Platform, and 2) contribution to goals of the EU-Africa Research and Innovation Partnership within FNSSA and cooperation with ongoing projects in the subject area to share innovations, maximize communication and facilitating technology transfer.
Uganda 2022-09-15 11:46:33 2025-09-15 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rosalind  Parkes-Ratanshi Parkes
ID: UNCST-2019-R000717
Exploring the Perceptions of Using Artificial Intelligence to Improve Outcomes in Maternal, Sexual and Reproductive Health in Sub-Saharan Africa - A Qualitative study
REFNo: HS2356ES

1. To explore the perceptions of stakeholders on opportunities for the application of responsible AI in MSRH in Sub-Saharan Africa. 2. To explore the perceptions of stakeholders on risks surrounding the application of responsible AI in MSRH in SSA. 3. To explore the perceptions of stakeholders on limitations of AI in MSRH in SSA. 4. To explore the perceptions of stakeholders on examples of best practices in existence for AI that can be applied in SSA.
UK 2022-09-15 11:12:18 2025-09-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Carolyn Nakisige
ID: UNCST-2021-R012699
The Social And Economic Impact of Cervical Cancer on Children in Uganda.
REFNo: HS2420ES

1) Determine how a woman's cervical cancer diagnosis and treatment impacts the social wellbeing of her children for women undergoing treatment for cervical cancer at the uganda cancer institute. 2)Determine how a woman's cervical cancer diagnosis and treatment impacts the economic situation of her children for women undergoing treatment for cervical cancer at the Uganda cancer institute. 3)Describe the demographics and characteristics of the women diagnosed with cervical cancer and undergoing treatment at the Uganda cancer institute.
Uganda 2022-09-14 13:17:34 2025-09-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Aleksander Braczkowski Ryszard
ID: UNCST-2019-R001345
Assessing the densities of four carnivore species and their conflict with local livestock farmers within and on the boundaries of Queen Elizabeth, Murchison Falls, Kidepo Valley, Pian Upe Wildlife Reserve and Lake Mburo National Parks
REFNo: NS331ES

Key objectives are to provide UWA and UNCST with updated density estimates of hyenas, lions, cheetahs and leopards using the latest spatially-explicit methods, and develop a conflict risk map for authorities for bettered allocation of resources to reduce lion and hyena attacks on livestock in future. I anticipate at least four key products to emerge from this research, 1) At least two high impact applied journal articles (eg. Journal of Applied Ecology or Frontiers in Ecology and the Environment), 2) a standardized, easy to repeat citizen science data collection protocol which uses the methods developed in 2022-2023 with Makerere students and other conservation stakeholders, 3) several training workshops with local scientists from Makere University, UWA staff, park staff and local lodges on density estimation techniques for large carnivores and 4) a conflict risk map covering these five protected areas which will be used by the Ugandan wildlife Authority to identify critical zones for conservation interventions to be applied in 2023 and beyond.
South Africa 2022-09-14 13:13:03 2025-09-14 Natural Sciences Non-Clinical Trial Non-degree Award
Isa Kabenge
ID: UNCST-2021-R011727
Water Quality Testing Fellowship program
REFNo: A221ES

To test the quality of water
Uganda 2022-09-12 18:35:11 2025-09-12 Agricultural Sciences Non-Clinical Trial Non-degree Award
James Baguma Natweta
ID: UNCST-2022-R010208
Assessment of factors influencing uptake and compliance to mercury free gold extraction and health, safety and environment and business practices among artisanal small – scale gold miners in three districts (Buhweju, Busia and Kassanda) in Uganda
REFNo: HS2405ES

To find out how mercury free gold processing affect the income and the livelihood of the miners and other stakeholders To explore the possible mitigation measures to the occupational and environmental hazards identified and which ones are in place in the three gold mining areas in Uganda. To identify the occupational and environmental hazards affecting the artisanal small scale gold miners. To ascertain the facilitators and the barriers to the uptake of mercury free gold mining technologies among ASGMs in the three different mining areas of Uganda. To identify the perceptions, attitudes, and practices about mercury free gold mining among trained and untrained artisanal small scale gold miners in the three different mining areas of Uganda.,The purpose of this baseline study is to assess the factors influencing uptake and compliance to mercury free gold extraction and health, safety and environment practices among artisanal small – scale gold miners in three districts (Buhweju, Busia and Kassanda) in Uganda.,
Uganda 2022-09-12 18:33:56 2025-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Willbroad Byamukama
ID: UNCST-2022-R010646
Adoption of Information Communication Technologies in Dissemination of Agricultural Information in Uganda. A case study of Rubanda, Mayuge Districts and Mbarara City
REFNo: A218ES

To establish ICT devices (Radio, mobile phones, television and computers) used by smallholder farmers in Rubanda, Mayuge Districts, and Mbarara City,To establish the extent of ICT usage for agricultural information dissemination in Rubanda, Mayuge Districts, and Mbarara City,To develop and validate a model for agricultural information dissemination in Rubanda, Mayuge Districts, and Mbarara City. ,To examine the factors influencing the adoption of ICT for agricultural information dissemination in Rubanda, Mayuge Districts, and Mbarara City.,To develop an Information Communication Technologies (ICT) model for agricultural information dissemination among smallholder farmers in Rubanda, Mayuge Districts, and Mbarara City. ,
Uganda 2022-09-12 18:31:03 2025-09-12 Agricultural Sciences Non-Clinical Trial Degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
A phase Ib study to assess the safety and immunogenicity of a recombinant adenovirus-based vaccine against plague in Uganda
REFNo: HS2387ES

Primary To investigate safety and tolerability of 5 x 1010 VP of the proposed ChAdOx1 Plague vaccine in healthy African adults aged 18 to 49 residing in Uganda, when given as one or two dose(s) intramuscularly with different prime-boost intervals Secondary To determine the immunogenicity of 5 x 1010 VP of the proposed ChAdOx1 Plague vaccine, in healthy African adults aged 18 to 49 years residing in Uganda when given as one or two dose(s) intramuscularly with different prime-boost intervals. Tertiary Exploratory immunogenicity assays to determine the immunogenicity of 5 x 1010 VP of the proposed ChAdOx1 Plague vaccine, in healthy African adults aged 18 to 49 years residing in Uganda when given as one or two dose(s) intramuscularly with different prime-boost intervals.
Uganda 2022-09-12 18:28:42 2025-09-12 Medical and Health Sciences Clinical Trial Non-degree Award
YVETTE SSEBUNYA
ID:
ELUCIDATING THE PRODUCTION PROCESS, COST OF PRODUCTION OF THE MUGUGA COCKTAIL ECF STABILATE AND ANALYSIS OF THE VACCINE SUPPLY CHAIN IN EASTERN AFRICA.
REFNo: A209ES


1.To describe the optimal vaccine production process of the Muguga cocktail.
2.To determine the cost of production of the Muguga stabilate and profitability of producing the Muguga cocktail vaccine.
3.To describe the East Coast Fever vaccine supply chain.
4.To identify alternative strategies to improve Muguga cocktail vaccine production and supply.

Uganda 2022-09-12 18:26:18 2025-09-12 Agricultural Sciences Non-Clinical Trial Degree Award
Carolyn Pelnik
ID:
How Important are Investment Indivisibilities for Development? Understanding Land Investment and its Long-Run Impacts in Uganda
REFNo: NS403ES

We are interested in understanding the long-run dynamics of the land market in rural and peri-urban Uganda and how land markets are related to poverty traps. We hope to better understand the extent to which poor households invest in land in order to exit poverty traps. This will help us to evaluate whether land may be a stepping stone to capital accumulation (perhaps via collateral), and the potential for policy intervention that can increase growth and development.
USA 2022-09-12 18:24:01 2025-09-12 Natural Sciences Non-Clinical Trial Non-degree Award
Philipp Händel Daniel
ID:
The effect of heterogeneity, scarcity and stochastic externalities on fishers’ behavior in a threatened common pool resource
REFNo: SS1418ES

1. Understand the effects of heterogeneity on cooperative behavior.
2. Understand how the impact of risk-taking on others changes the willingness to take risk.
3. Understand how scarcity affects cooperative behavior.
Germany 2022-09-12 18:21:28 2025-09-12 Social Science and Humanities Non-Clinical Trial Degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
IMPACTS OF ENTEBBE HOSPITAL CLOSURE ON THE CLIENTS’ HEALTH STATUS DURING THE COVID-19 PANDEMIC IN UGANDA
REFNo: SS1425ES

2. To determine the extent of impacts on the health status of the previously registered clients of Entebbe RRH.,1. To understand the options used by patients to cope-up with access to necessary health services during the closure of Entebbe RRH.,To determine the impacts of Entebbe Regional Referral Hospital (ERRH) general services closure during the COVID-19 pandemic (March 2020 – April 2022) on registered and non-registered OPD clients in the Entebbe catchment area Uganda.,
Uganda 2022-09-12 18:13:58 2025-09-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rita Nakalega
ID: UNCST-2019-R000599
A NOVEL VIDEO-BASED INTERVENTION TO ENHANCE OPTIMAL UPTAKE OF MALARIA PREVENTIVE THERAPY: A PILOT STUDY OF A HEALTH EDUCATIONAL APPROACH TO MALARIA PREVENTION DURING PREGNANCY
REFNo: NS384ES

1. Develop the PreVent intervention,
Uganda 2022-09-08 20:06:17 2025-09-08 Natural Sciences Non-Clinical Trial Non-degree Award
Lorenzo Casaburi
ID:
An Evaluation of Contract Farming for Biofortified Crops
REFNo: SS1416ES

Main objective. The modernization of the agricultural sector is a key process for economic growth. Which organizational forms can foster this modernization? In recent decades, academics, practitioners, and policymakers have looked at contract farming as a promising option to foster commercialization of smallholder-based agricultural sectors and improve farmers’ market access. Compared with spot markets, contract farming can exploit increasing returns to scale in processing, transport, and branding, can overcome failures in credit and information markets, and can reduce demand and supply risk. At the same time, compared with vertical integration, contract farming preserves smallholders’ land property rights and thus avoids the establishment of large plantations. In the proposed project, we will use a randomized experiment to evaluate the impact of contract farming on plot productivity and farmer income, and to study the returns to investment for the contract farming companies, once accounting for any defaults on in-kind input provision. The implementation of the contract farming intervention will be managed by two partner agricultural companies according to their standard business procedures. The research team will be in charge of running farmer surveys to measure the effect of the contract farming. The academic research team is collaborating with Harvest Plus, an international organization whose goal is to develop and promote new, more nutritious varieties of stable food crops with higher amounts of micronutrients.

Specific objectives:

1. First, we will study the impact of contract farming on agricultural production, income, and profits. In order to measure profits, we will collect detailed agricultural labor and wage data. We will also study the impact of the treatment on other income-generating activities, including non-agriculture business activities. Measuring agricultural production and income implies gathering information on total output harvested and output sold, prices, and costs of inputs (seeds, fertilizers, hired work, etc.). Similarly, we will also collect data on other potential non-agricultural activities the household may be involved
2. Second, we will assess the overall extent to which enrollment in the contract farming scheme affects farmer technology adoption and input intensity, both for biofortified beans and for crops not targeted by the contract. Outcomes of interest include land preparation costs, plantlets per acre, fertilizer and manure applications, crop maintenance, and agrochemicals/pesticides. We will collect data on farming tools used by the households, fertilizers, pesticides, etc. to quantify changes on these variables that may occur during the time span of the project.
3. Third, we will study whether joining the contract farming scheme has an impact on food security. There is debate over the impact of a shift to commercial farming, as this may involve focusing production on crops that are not directly consumed in the household (see, e.g., Schneider, 2010). We will collect data on food security in order to assess the impact of the treatment on this outcome. Specifically, we will ask to the farmers on coping strategies deployed during eventual hunger periods the household may suffer o have recently suffered.
4. Fourth, we will try to measure operating costs and benefits of the companies. In particular, we will use companies’ administrative data to measure the prevalence of farmer default and crop side-selling and thus to quantify the return on investment for the companies. Partner companies will provide a detailed dataset with the relevant variables needed to perform this analysis.
5. As an additional contribution, we will also study the determinants of smallholder participation: we will correlate the choice to join the contract farming scheme (in the treatment villages) with baseline characteristics of the farmers. Several scholars have expressed concerns over the contract farming model, suggesting it may exclude households that are less productive and poorer at baseline. The take-up analysis will assess whether this concern holds or not in our setting.
Italy 2022-09-08 16:09:36 2025-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Allan Kalungi
ID: UNCST-2022-R009843
Unravelling the genetic risk underlying common mental illnesses (major depressive disorder, generalized anxiety disorders, suicidality and attention-deficit hyperactivity disorder) and alcohol and substance abuse among a rural general population cohort in south-western Uganda
REFNo: SS1404ES

Unravelling the genetic risk underlying common mental illnesses (major depressive disorder, generalized anxiety disorders, suicidality and attention-deficit hyperactivity disorder) and alcohol and substance abuse among a rural general population cohort in south-western Uganda
Uganda 2022-09-08 16:05:10 2025-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
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