Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Performance Evaluation of the Alinity m HIV-1 Assay using DBS for Detection of HIV-1 in Infants.
REFNo: HS2586ES

To verify the performance (sensitivity and specificity) of the Alinity m HIV-1 Qualitative Test against routine Cobas Ampliprep/Taqman HIV-1 Qualitative Test Version 2.0 (DBS)- for early diagnosis of HIV-1 in exposed infants. ,
 Uganda 2022-12-12 15:23:01 2025-12-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brian Kiira Alex
ID:
Emerging Ethics and Human Rights Issues in the Digitization of Population Register Systems
REFNo: SS1383ES

1. To nurture a new generation of scholars and practitioners via direct mentoring from senior scholars and experienced practitioners in the field, immersion into academic, policy and practitioner networks, debates and institutions, exposure and visibility through publications and communications based in the global South. 2. To support active collaboration between fellows as well as between IUSSP, WiSER, ISER and IIGH-USC. 3. To nurture a generation of scholars who will challenge experienced practitioners, senior scholars and established systems to consider new perspectives, rethink established assumptions and question dominant paradigms for population register systems. 4. To facilitate stronger engagement by population scientists on contemporary issues and support interdisciplinary collaboration with established scholars from other disciplines and early career researchers and practitioners around ethics and human rights in the digitization of population register systems.
Uganda 2022-12-09 12:35:52 2025-12-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
FRED SEMITALA COLLINS
ID: UNCST-2020-R014096
 Differentiated Services Delivery Outcomes in Uganda: Facilitators, barriers, and qualitative systems mapping.
REFNo: HS2497ES

To evaluate the performance and quality of DSD models in the delivery of HIV/TB services in Uganda.
Specific Objectives:
1. To assess the performance and Quality of intensive and less intensive DSD models of care for HIV/TB TB services in Uganda.
2. To elicit stakeholders’ perspectives on facilitators of and barriers to improved DSD performance in Uganda.

3. To identify system elements (systems mapping) and determine how their relationships in health care affect both positively and negatively the performance of DSD service delivery in Uganda.

 Uganda 2022-12-08 15:05:56 2025-12-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Mafigiri Kaawa
ID: UNCST-2019-R001276
 Rapid Anthropological Study in Districts Affected by Ebola (Sudan Strain) in Uganda
REFNo: SS1542ES

The general objective of this study is to explore the socio-cultural construction of the drivers of the current Ebola virus disease (EBV) transmission and community resistance to Ebola response strategies in Uganda
 Uganda 2022-12-08 13:08:41 2025-12-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Barasa Chemutai Mercy
ID:
LEVERAGING TEACHER CONCERNS IN CURRICULUM REFORM: A MIXED METHODS STUDY OF SELECTED GOVERNMENT SCHOOLS IN UGANDA
REFNo: SS1541ES

iv. To explain the relationships between curriculum reform strategies, teacher concerns and the quality of implementation of the LSC using themes emerging from interviews with teachers, school administrators, and national education officials. ,iii. To compare the influence of support strategies by school administrators on the nature of teacher concerns and the quality of implementation of the curriculum in three different school contexts.,ii. To determine the extent to which teacher concerns mediate the relationship between the curriculum reform strategies and the quality of implementation of the CBC.,i. To investigate the nature of the concerns of Ugandan secondary school teachers about the CBC.,to determine the role of teacher concerns in the lower secondary curriculum reform process in Uganda by investigating the relationships between the strategies of curriculum reform, the concerns of teachers implementing the reform, and the quality of the curriculum implementation, and hence to explore ways in which change facilitators can leverage teacher concerns for successful reform.,
 Uganda 2022-12-08 12:19:11 2025-12-08 Social Science and Humanities Non-Clinical Trial Degree Award
Simon Nampindo Takozekibi
ID: UNCST-2022-R009914
 Population Census of African Lion and Spotted Hyena in Murchison Falls Protected Area, Uganda
REFNo: NS447ES

To estimate the density and abundance of the African lion and spotted hyena in Murchison Falls National Park, Bugungu and Karuma Wildlife Reserves using the Spatially Explicit Capture-Recapture (SECR) framework.
 Uganda 2022-12-08 12:16:46 2025-12-08 Natural Sciences Non-Clinical Trial Non-degree Award
Rose  Nabatanzi
ID:
Characterization of the latent reservoir among HIV-infected individuals on long-term antiretroviral therapy
REFNo: HS2454ES

1. To validate the intact proviral DNA assay in measuring the latent HIV reservoir size for HIV subtypes A and D
2. To compare the size of the latent HIV reservoir among HIV-infected optimal and suboptimal immune responders on long-term ART
3. To compare the size of the latent HIV reservoir between subtypes A and D among HIV-infected individuals on long-term ART
4. Determine the levels of T cell immune activation/exhaustion among ART-treated individuals comparing subtypes A and D.

 Uganda 2022-12-08 12:15:54 2025-12-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
 ACCESS TO HIV, TUBERCULOSIS AND MALARIA SERVICES: A GENDER-BASED ASSESSMENT FOR UGANDA
REFNo: HS2549ES

1. To determine the extent to which Uganda is achieving targets of gender interventions in the National HIV&AIDS Strategic Plan (NSP) 2020/21 to 2024/25 and the Sustainable Development Goals.
2. To determine progress against national gender-related targets, highlight key issues affecting gender and HIV, TB as well as malaria responses and the actions needed.
3. To explore communities’ perspectives on the performance and benefits of gender and HIV, TB and malaria response interventions.
4. To generate recommendations aimed at enhancing social accountability, quality and efficiency of interventions in the gender and HIV, TB and malaria response in Uganda.

 Uganda 2022-12-08 11:40:48 2025-12-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Muzaale
ID: UNCST-2022-R009515
 Investigating the predictors of acceptability of cervical cancer screening among women living with HIV in Kalungu district.
REFNo: HS2573ES

Goal of the study:
To investigate the predictors of acceptability of cervical cancer screening among women living with HIV in Kalungu district.

Specific objectives:
a) To examine the individual factors influencing acceptability of cervical cancer screening among women living with HIV in Kalungu district.
b) To assess the institutional/health facility factors that influence acceptability of cervical cancer screening among women living with HIV in Kalungu district.
c) To investigate the socio-economic factors influencing cervical cancer screening acceptability among women living with HIV in Kalungu district.

Uganda 2022-12-06 16:31:30 2025-12-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Bjorn Van Campenhout -
ID: UNCST-2020-R014080
 Quality and food safety in the Ugandan dairy value chain
REFNo: SS1520ES

To measure the impact of visualizing milk quality attributes to farmers and milk collection centers (MCCs) on the compositional quality of milk (butter fat content and solid non-fat content) at both levels.
Belgium 2022-12-06 16:29:54 2025-12-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
PEACE MUTUUZO REGIS
ID:
Public Policy and Gender Transformation: A Case of affirmative action for Women’s Political Participation in Uganda
REFNo: SS1504ES

Main objective

To examine the effect of affirmative action for women’s political participation on gender transformation in Uganda between 2011-2021.


Specific objectives

1. To assess the existing policies that promote women’s political participation in Uganda.
2. To examine the effect of affirmative action for women’s political participation on gender relations in Parliament and District Local Councils.

3. To examine the effect of affirmative action for women’s political participation on gender relations in the local community.

4. To explore the structural barriers that prevent women in the political space from achieving gender transformation.

5. To identify other strategies that can be employed to achieve gender equality in Uganda other than affirmative action.

Uganda 2022-12-06 16:27:05 2025-12-06 Social Science and Humanities Non-Clinical Trial Degree Award
Santorino Data
ID: UNCST-2019-R001487
 MamaOpe Pneumonia Diagnostic device: A feasibility, acceptability and effectiveness evaluation in Uganda
REFNo: HS2533ES

We aim to determine the feasibility and acceptability of a wearable device by frontline health workers in the chest examination Determine the accuracy of the wearable pneumonia diagnostic device in measuring the respiratory rate, determination and interpretation of lung sounds using an algorithm to inform the likely presence or absence of pneumonia. ,
 Uganda 2022-12-06 16:21:06 2025-12-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sarah Walker
ID:
The regional dynamics of deforestation. Evidence from Kenya and Uganda
REFNo: SS1485ES

Given the pervasiveness of insecure land tenure institutions around the developing world, and the role of historical institutions in shaping preferences and behavior, it is important to understand how the design of PES programs may interact with historical land tenure structures. In this project, we design a willingness to accept experiment, and framed field experiment, across three regions of Uganda to answer the following questions:

1. What is the optimal design of an avoided deforestation PES program in Uganda?
2. How do land tenure institutions impact the design of an avoided PES program in Uganda?
3. How does the security of land tenure impact deforestation behavior and trust in Uganda?
 USA 2022-12-05 12:03:29 2025-12-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paddy Asiimwe Junior
ID:
ADVANCED LOCALIZATION TECHNIQUES ON SMART DEVICES FOR INCLUSIVE LOCATION-BASED SERVICES: A FOCUS ON HEALTHY AGING FOR THE ELDERLY WITH DEMENTIA IN RURAL COMMUNITIES
REFNo: SIR169ES

The main objective is to develop a remote-based comprehensive monitoring and positioning system for people with dementia in rural communities.
Specific objectives
1. To conduct a site survey in Apac district to identify homes and explore the challenges people living with dementia face.
2. To analyze data collected.
3. To design a comprehensive energy efficiency monitoring and positioning system for people with dementia in rural communities.
4. To develop and test the system in Apac District.

 Uganda 2022-12-01 10:53:14 2025-12-01 Engineering and Technology Non-Clinical Trial Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
 Impact of Cachexia on Physical Activity, Performance and Functional measures in Advanced Cervical Cancer Patients at the Uganda Cancer Institute
REFNo: HS2467ES

iii) To explore the impact of cachexia on HRQOL among advanced cervical cancer patients receiving chemotherapy at the Uganda Cancer Institute,ii) To examine the impact of cachexia on inability to receive treatment among patients with advanced cervical cancer at the Uganda Cancer Institute,i) To estimate the impact of cachexia on activity of daily living among patients with advanced Cervical cancer receiving chemotherapy at the Uganda Cancer Institute,To examine the impact of CC on physical activity, performance and functional measures among patients with advanced CxCa receiving chemotherapy at the Uganda Cancer Institute,
 Uganda 2022-12-01 10:50:14 2025-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benard Ssebide Jasper
ID: UNCST-2022-R009850
 Gastrointestinal symbiont communities of great apes and other non-human primates: bioindicators for tropical ecosystem health and their impact on apes’ health
REFNo: HS2416ES

The overall goal is to study gastrointestinal symbiotic communities of African great apes and other non-human primates across Albertine Rift. We will explore relationships between the endosymbionts and the host organism as well as the relationships within the ecosystem. For the helminths, the impact on the host as well as epidemiology will be studied at the wildlife - domestic animals - human interface. Specifically:

Identification of parasite spectrum and infection burden in BINP great apes across the park and detection of possible reservoirs of zoonotic parasites at the BINP wildlife – domestic animal – human interface by screening selected animal hosts.

Evaluation of the role of strongylid nematodes in clinically ill great apes and investigation of the forces driving the zoonotic parasite infections by analyzing the environmental, host, and anthropogenic factors.

Characterizing the relationships within the endosymbiont communities, between the endosymbiont communities and the habitat, the relationships between the anthropogenic disturbance of ape habitats and endosymbiont communities and evaluation of the endosymbiont interspecies transmission.

Analysing the gut metabolite composition in non-human primates to detect molecular phenotypic difference between clinically ill animals and healthy individuals.

To increase the capacity of disease surveillance system in the area and to decrease the risk of parasite transmission between humans, domestic animals and wildlife, increasing the awareness of pathogen transmission in the local community.

 Uganda 2022-11-30 14:14:47 2025-11-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 SAFETY, PHARMACOKINETICS AND PRELIMINARY EFFICACY OF HERBAL PRODUCTS FOR THE TREATMENT OF ACUTE RESPIRATORY VIRAL INFECTIONS INCLUDING SARS-COV2 IN UGANDA; PHASE 2A OPEN LABEL CLINICAL TRIAL
REFNo: HS2548ES

The general objective is to assess the safety, pharmacokinetics and preliminary efficacy of TazCoV and Vidicine for the treatment of acute respiratory viral infections (SARS-CoV2, RSV and Influenza A/B) in Uganda.
Specific objectives
1. To determine the safety and pharmacokinetics of TAZCOV and Vidicine herbal products among adult patients with acute respiratory infections due to laboratory-confirmed SARS-CoV2, RSV and Influenza A/B

2. To determine the extent of SARS-CoV2, RSV and Influenza A/B viral clearance among adult patients with acute viral respiratory infection treated using TAZCOV and Vidicine

3. To establish time-to-remission of symptoms among patients with acute respiratory infections due to laboratory-confirmed SARS-CoV2, RSV and Influenza treated with TAZCOV or Vidicine

4. To evaluate disease progression among patients with acute respiratory infections due to laboratory-confirmed SARS-CoV2, RSV and Influenza treated with TAZCOV or Vidicine
 Uganda 2022-11-29 12:38:24 2025-11-29 Medical and Health Sciences Clinical Trial Non-degree Award
Robert Buwule Stalone
ID:
Use of COVID-19 surveillance applications in Uganda
REFNo: SS1477ES

To design a health-based ICT COVID-19 surveillance framework for community health,To establish the drivers and barriers of adopting health-based ICT surveillance applications in Uganda,To examine the adoption and integration of the surveillance applications in the community health practices in Uganda,To assess the efficacy of the existing health-based ICT surveillance applications in the communities in Uganda,To identify health-based ICT surveillance applications developed to mitigate the COVID-19 pandemic in Uganda,To establish the level of application of Covid-19 Surveillance applications ICT innovations in community health during the COVID-19 pandemic in Uganda with a view of suggesting a health-based ICT framework for community health,
 Uganda 2022-11-29 12:33:19 2025-11-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jenna Grzeslo
ID:
BRAC Girls Talk: Exploring the feasibility of an interactive voice response for Youth Empowerment Program in Uganda
REFNo: SS1401ES

To evaluate the level of usability, accessibility, and relevancy of gamified content to Adolescent Girls and Young Women(AGYW) and to determine the relationship between engaging with IVR-enabled ELA content on early outcomes and proxies for self-efficacy, economic empowerment, and social empowerment. Our second research objective is focused on the relevance of the BRAC Girls Talk content to AGYW. In order to explore this objective, we will conduct focus group discussions (FGDs) with program participants.
 USA 2022-11-29 12:26:24 2025-11-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Helen Nkabala Nambalirwa
ID:
BARRIER ASSESSMENT ON IMPEDIMENTS TO UGANDA POLICE WOMEN’S PARTICIPATION IN UN PEACE SUPPORT OPERATIONS.
REFNo: SS1535ES

To establish the level of participation of Ugandan women police officers in UN Peace Support Operations
To examine the limitations in the participation of Ugandan women police officers in UN Peace Support Operations.
To suggest the steps that can be taken to increase the level of participation of Uganda women police officers in the UN Peace Support Operations.

 Uganda 2022-11-28 12:24:37 2025-11-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
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