Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
WABUSA DAVID FRANCIS
ID:
IMPLICATIONS OF LAND TENURE SYSTEMS ON FOOD SECURITY IN MBALE DISTRICT-EASTERN UGANDA
REFNo: SS2720ES

iv. Recommend policy interventions and strategies to improve land tenure systems in Mbale district.,iii. Identify the key challenges and barriers that affect food security for households in Mbale, Uganda.,ii. Determine the implications of the land tenure systems for household food security in Mbale, Uganda. ,i. Assess the existing land tenure systems in Mbale, Uganda ,To understand the implications of land tenure systems on food security of households in Mbale district. ,
Uganda 2024-09-23 13:15:34 2027-09-23 Social Science and Humanities Non-Clinical Trial Degree Award
Henry Kajumbula Mawerere
ID: UNCST-2019-R001531
Comparison of community and hospital Antibiotic use practices, Susceptibility and resisTance and determinants of care seeking among patients with Urinary Tract Infections (CAST-UTI)
REFNo: HS4458ES

6. Determine the outcome of infections.,5. Assess the treatment practices of healthcare workers for acute UTIs in CDROs and hospitals.,4. Examine the resistance profiles for differences between neighbourhoods (Namuwongo and Muyenga),3. Determine the appropriateness of treatment based on standard treatment guidelines for acute UTIs in the community (based on organism and resistance profile,2. Explore the social context of antibiotic prescribing and use in the community. ,1. Determine and compare the resistance profiles of the disease-causing organisms in community drug retail outlets (CDRO’s)/clinics, and in hospitals/ WHO-GLASS ,
Uganda 2024-09-23 13:14:32 2027-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Nyeko
ID: UNCST-2021-R012815
Acute myeloid leukaemia in children in a resource-limited setting: epidemiology, management, and outcomes in Uganda
REFNo: HS4479ES

Aim of the study
This doctoral study aims to investigate paediatric AML in Uganda and other African countries, namely the incidence and prevalence of paediatric AML, the AML biological characteristics, the supportive care needs, and overall survival after the introduction of an adapted AML treatment protocol with a reduced-intensity induction regimen.

Specific objectives
1. To describe the incidence and prevalence of paediatric AML in Uganda.
2. To evaluate paediatric AML management and outcomes in Uganda and other African countries based on different treatment protocols.
3. To determine the risk factors for induction failure and treatment-related morbidity and mortality in children with AML.
4. To conduct a “proof-of-concept” study to test the recommendations of the SIOP-PODC (renamed SIOP Global) adapted guidelines for paediatric AML in resource-limited settings.
5. To identify the limitations in supportive care (anti-bacterial, blood products, and intensive care) needs in the treatment of paediatric AML in Uganda.

Uganda 2024-09-23 13:05:19 2027-09-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Muniru Sewanyina
ID: UNCST-2021-R013988
CORPORATE GOVERNANCE PRACTICES AND NON-PERFORMING LOANS OF COMMERCIAL BANKS IN GREATER BUSHENYI DISTRICTS; WESTERN UGANDA
REFNo: SS3114ES

To ascertain the moderating influence of interest rates on non-performing loans of commercial banks in Greater Bushenyi Districts, western Uganda, To examine the extent to which board compensation influences non-performing loans of commercial banks in Greater Bushenyi Districts western Uganda ,To determine the extent to which relationship between shareholders\' rights and non-performing loans of commercial banks in Greater Bushenyi Districts, western Uganda,To examine the extent to which financial transparency influences non-performing loans of commercial banks in Greater Bushenyi Districts, western Uganda ,To assess the extent to which board accountability influences non-performing loans of commercial banks in Greater Bushenyi Districts, western Uganda, The purpose of this study will be to assess the effect of corporate governance practices on non-performing loans of commercial banks in Greater Bushenyi Districts; Western Uganda,
Uganda 2024-09-23 12:16:25 2027-09-23 Social Science and Humanities Non-Clinical Trial Degree Award
Helen Byakwaga
ID: UNCST-2019-R001168
CD4 Cell Count at Antiretroviral Therapy Initiation or Re-initiation (CAIR)
REFNo: HS4944ES

To assess advanced HIV disease among people living with HIV initiating or re-initiating ART 1) Assess the proportion of participants presenting with advanced HIV disease prior to ART initiation/re-initiation among those enrolling in HIV care via CD4 cell count testing and WHO staging. 2) Description of participants re-entering care based on viral suppression and/or self-report of HIV care. 3) Assess barriers to HIV care including barriers associated with mental health and alcohol use. 4) Pilot test data variables to capture re-entry into care and re-initiation of ART and barriers to HIV care and ART
Uganda 2024-09-23 12:08:10 2027-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MUGABE AMOS
ID: UNCST-2023-R007328
OCCURRENCE, ANTIMICROBIAL AND HEAT RESISTANCE PROFILES OF SALMONELLA SPECIES IN THE INFORMAL DAIRY VALUE CHAIN OF UGANDA
REFNo: A514ES

5. Evaluate the heat resistance profiles of Salmonella in the dairy value chain.,4. Evaluate the antibiotic resistance profiles of Salmonella in the dairy value chain.,3. Determine the serotypes of Salmonella in the dairy value chain. ,2. Estimate the prevalence of Salmonella in the dairy value chain.,1. Determine the extent to which milk producers and handlers in the dairy value chain are aware of milk quality and best dairy practices. ,To assess the serotypes, antibiotic resistance and heat resistance profiles of Salmonella in the dairy chain.,
Uganda 2024-09-23 12:05:28 2027-09-23 Agricultural Sciences Non-Clinical Trial Degree Award
Emmanuel Mande
ID: UNCST-2023-R007045
Artemisinin Resistance Surveillance Network in Sub-Saharan Africa (ARSUNA)
REFNo: HS4644ES

To evaluate socio-demographic, clinical and malaria-history factors on treatment outcome and on the carriage of resistant malaria parasites.,To evaluate day 3 parasitemia among 200 patients with P. falciparum malaria treated with an ACT.,To assess the relatedness and origin of P. falciparum isolates with an artemisinin resistant geno- and phenotype by molecular analysis. ,To evaluate the in vitro susceptibility to (dihydro) artemisinin and ACT partner drugs (e.g. lumefantrine) among selected/suspicious P. falciparum isolates.,To assess the molecular characteristics of P. falciparum isolates from 200 patients with malaria, with a special focus on, but not limited to, molecular markers of artemisinin resistance, e.g., K13, and Pfmdr1.,
Uganda 2024-09-23 11:59:33 2027-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BOSCO AGABA BEKIITA
ID: UNCST-2019-R000549
Uganda Malaria Indicator Survey 2024
REFNo: HS4950ES

To determine risk factors for malaria parasitemia in Uganda,To measure indicators of knowledge, attitudes, and behaviour related to malaria control in Uganda (Community prevention and control efforts, Malaria vaccine knowledge and acceptance),To estimate core malaria programme coverage indicators in Uganda (Measure the extent of ownership, use and disposal of mosquito bed nets ● Assess coverage of the IPTp programme for pregnant women ● Coverage and uptake of IRS ● Identify practices used to treat malaria among children under age 5 and the use of specific antimalarial medications ● Assess percent of children under five with suspected or confirmed malaria who received treatment with ACTs within 24 hours of onset of fever. ● Access to malaria testing/ diagnosis ● Coverage, attitudes, and perceptions about SMC ● Determine the species of plasmodium parasite most prevalent in Uganda ),To obtain estimates of the magnitude and distribution of malaria parasitemia among children aged 6-59 months in Uganda,The main objective of the UMIS is to obtain population-based estimates of malaria indicators including the prevalence of malaria, to inform strategic planning and programme evaluation,
Uganda 2024-09-23 11:57:13 2027-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ruth Namazzi
ID: UNCST-2020-R014305
ESTABLISHMENT OF A PEDIATRIC CANCER PATIENT NAVIGATION PROGRAM
REFNo: HS4909ES

1. To determine the barriers and facilitators of accessing care and remaining in care at Mulago National Referral Hospital, Pediatric Hematology and Oncology service 2.To develop a patient centered navigation program for patients seeking care and in care for cancer at MNRH 3.To determine the patient - parent navigation requirements in seeking and remaining in cancer care program at MNRH
Uganda 2024-09-13 11:00:38 2027-09-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alimah Komuhangi
ID: UNCST-2020-R014709
EFFECTIVENESS AND CONTEXTUAL FACTORS OF COMMUNITY-BASED PEER-LED SEXUAL AND REPRODUCTIVE HEALTH EDUCATION ON RISKY SEXUAL BEHAVIOUR FOR ADOLESCENT GIRLS AND YOUNG WOMEN IN MOROTO DISTRICT, KARAMOJA REGION.
REFNo: HS4697ES

To establish the preliminary effectiveness of the community-based peer-led sexual and reproductive health education on SRH knowledge among AGYW in Moroto District.,To determine the preliminary effectiveness of the community-based peer-led sexual and reproductive health education on risky sexual behavior among AGYW in Moroto District.,To explore the contextual factors that might influence the implementation of a CBPL SRH education among AGYW in Moroto District.,To explore the contextual factors that might shape the implementation of a community-based peer-led sexual and reproductive health education and its effectiveness on SRH outcomes among AGYW in Moroto District.,
Uganda 2024-09-13 10:18:43 2027-09-13 Medical and Health Sciences Non-Clinical Trial Degree Award
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