Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Daniel Omuna
ID: UNCST-2025-R019635
CLIMATE VARIABILITY AND WATER SECURITY AMONG SELECTED COMMUNITIES IN KUMI DISTRICT, EASTERN UGANDA
REFNo: NS1160ES

i. To determine the effect of climate variability on surface and groundwater availability in Kumi district using GIS and remote sensing.
ii. To examine the effects of climate variability on accessibility to water in selected communities in Kumi district.
iii. To determine the portable water quality of both surface and ground water in Kumi district.
iv. To establish community resilience and adaptability to water insecurity caused by climate variability in Kumi district.

Uganda 2026-04-10 19:05:54 2029-04-10 Natural Sciences Non-Clinical Trial Degree Award
Flavia Zalwango Kabuye
ID: UNCST-2025-R022929
The role of participatory communication strategies in enhancing uptake of childhood routine immunization vaccines in intersectionally vulnerable communities in Uganda
REFNo: SS4954ES

1. To understand health communication preferences and patterns on Koome main island

2. To explore stakeholders’ perceptions of the effectiveness of participatory vaccine communication strategies used on Koome main island between 2020 and 2025

3. To propose culturally appropriate participatory strategies to enhance vaccine communication among intersectionally vulnerable communities in Uganda

Uganda 2026-04-10 19:01:37 2029-04-10 Social Science and Humanities Non-Clinical Trial Degree Award
Anthony Nsubuga Mutebi
ID:
The consequences of biodiversity loss and land use change on infectious disease emergence
REFNo: NS1176ES

Objectives
This project focuses on the understanding of epidemic emergence by dissecting the most initial processes and dynamics of infectious disease emergence in rural settings of seeding regions based on a multi-host and multi-pathogen system. Specifically, we will concentrate on the transition from pre-emergence to emergence based on a comprehensive and multidisciplinary approach by linking the fields of human and veterinary medicine, clinical virology, molecular biology, disease ecology and modelling. We aim to detect and model arbovirus infection and transmission patterns in mosquitoes, livestock (cattle and goats as hosts for Rift Valley fever virus and chicken as hosts for West Nile virus) and humans (hosts for Dengue virus, Chikungunya virus, Zika virus and Yellow fever virus) under varying ecological and socioeconomic conditions at the interface to natural biodiversity hotspots in order to identify common patterns and drivers of emerging diseases.
Defining early transmission dynamics is most critical for prevention and containment of local outbreaks before they cause epidemics or pandemics. Our specific objectives are:
(i) To provide a thorough phenotypic and molecular characterization of pre-epidemic virus variants including previously unknown viruses isolated from mosquitoes, livestock and humans from rural regions in Uganda at the interface to the main African ecosystem types, tropical lowland, gallery and montane forest. Pre-epidemic variants will be compared to their cosmopolitan counterparts aiming at identifying distinguishing characteristics evolved during the emergence process.
(ii) To study the genetic adjustment of pre-epidemic variants by analysing intra- and inter-host genetic diversity and selective pressures as drivers for virus evolution and diversification after spillover infections to new vectors and hosts.
(iii) To probe the host transcriptome response to infection with pre-epidemic arboviruses at the single cell level aiming to gain insight into the evolutionary fine scaling of arboviruses in the transition from pre-emergence to emergence.
(iv) To assess the influence of different socioeconomic and ecological factors for the risk of virus transmission and disease outbreaks through phylogeographic reconstruction of the virus spatial movement and ecological niche factor analysis.
(v) To model virus and host distribution as well as infection risk under current and future climatic and land use scenarios based on collected field data.

Uganda 2026-04-10 18:57:00 2029-04-10 Natural Sciences Non-Clinical Trial Non-degree Award
RONALD ALIIJA
ID: UNCST-2025-R022107
ADOPTION OF DIGITAL FINANCIAL INNOVATIONS, FINANCIAL INCLUSION, AND FINANCIAL PERFORMANCE OF SMALL AND MEDIUM ENTERPRISES IN KAMPALA CAPITAL CITY, CENTRAL UGANDA
REFNo: SS5110ES

1) To examine the relationship between adoption of digital financial innovations and financial performance of SMEs in Kampala Capital City, Central Uganda. 2) To examine the relationship between adoption of digital financial innovations and financial inclusion among SMEs in Kampala Capital City, Central Uganda. 3) To find out the relationship between financial inclusion and the financial performance of SMEs in Kampala Capital City, Central Uganda. 4) To establish the mediating role of financial inclusion in the relationship between adoption of digital financial innovations and the financial performance of SMEs in Kampala Capital City, Central Uganda.
Uganda 2026-04-10 18:55:32 2029-04-10 Social Science and Humanities Non-Clinical Trial Degree Award
Salaviruse Ahimbisibwe
ID: UNCST-2022-R011048
Landscape analysis of the One Health ecosystem supporting interventions against zoonotic diseases in Uganda
REFNo: SS5023ES

Main Objective
1. To characterise the perceptions of different stakeholders relevant to Taenia Solium control to support co-design of a SUSTAIN-specific acceptability and feasibility framework for use in the trial evaluation.
Specific Objectives
1. Review the policy document and health activities landscape associated with One Health, public and veterinary health campaigns and the stakeholder environment in the SUSTAIN study districts relevant for zoonotic and Neglected Tropical Disease activities in Uganda.
2. Validate local systems, governance and stakeholder mapping with relevant stakeholders in Uganda.
3. Understand the distribution of and roles and responsibilities of key stakeholders involved in the knowledge generation and translation, decision-making and policy development, and programme planning and implementation relevant for Taenia Solium and NTDs in Uganda, using SUSTAIN as a case study
4. Ensure the most relevant district-level human and animal health officials are able to communicate and have a good understanding of the cross-sector system surrounding, and rationale for, SUSTAIN intervention for Taenia Solium control. Especially appreciating the different perspectives and any potential shared objectives across sectors.
5. Develop and validate a theory of change for the joint MDA strategy, especially identifying the elements of One Health implementation i.e. priorities for communication, co-ordination and collaboration and any capacity gaps that may need addressing to fulfil these.
6. Identify indicators of acceptability and evaluate prospective (perceived) acceptability for implementers and recipients through pre-intervention consultation (Key Informant Interviews and Focus Group Discussions), mapped against the seven domains of the theoretical framework of acceptability.
7. Document any opportunities, barriers and facilitators to implementing cross-sectoral control programmes such as SUSTAIN.
Uganda 2026-04-10 18:54:29 2029-04-10 Social Science and Humanities Non-Clinical Trial Degree Award
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