Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jafesi Pulle
ID: UNCST-2020-R014213
Feasibility Testing and Scaling of Two-Way Messaging in the ACT Platform
REFNo: HS4968ES

Aim 1: Optimize the 2-way SMS functionality within the ACT platform.

Aim 2: Understand integration and uptake of the 2-way SMS functionality within the ACT platform using the RE-AIM implementation framework

Uganda 2024-10-08 12:01:12 2027-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anifa  Miiro
ID:
MANAGEMENT STYLES, CULTURAL DIVERSITY AND PERFORMANCE OF SELECTED INTERNATIONAL NON–GOVERNMENT ORGANISATIONS IN UGANDA
REFNo: SS3196ES

vi. To establish the effect of Government policy as an intervening factor on the relationship between management styles, cultural diversity, and performance of International Non-Government organization in Uganda. ,v. To establish the effect of Work environment as an intervening factor on the relationship between management styles, cultural diversity, and performance of International Non-Government organization in Uganda. ,iv. To assess the effect of Language diversity on performance of International Non-Government Organizations in Uganda,iii. To assess the effect of Religion diversity on performance of International Non-Government Organizations in Uganda.,ii. To assess the effect of Strategic style on performance of International Non-Government Organizations in Uganda,i. To assess the effect of Visionary Management style on performance of International Non-Government Organizations in Uganda.,The purpose of the study is to examine the effect of Management styles , Cultural diversity and performance of selected International Non-Government organizations in Uganda.,
Uganda 2024-10-08 11:16:46 2027-10-08 Social Science and Humanities Non-Clinical Trial Degree Award
Ivan Kahwa
ID: UNCST-2021-R012730
Chemical characterization of Ugandan propolis and its activity against multidrug-resistant bacteria
REFNo: HS5018ES

To investigate the antibacterial mechanisms of propolis extracts, propolis-antibiotic, and nanopropolis combinations by destroying cell wall membranes and resisting biofilm formation.,To prepare a nano-emulsion loaded with propolis extracts and test its in vitro antibacterial activity against resistant bacterial strains and multidrug-resistant bacteria.,To investigate the synergistic activity of propolis extracts with potent antibacterial activity in combination with selected antibiotics against resistant bacterial strains and multidrug-resistant bacteria. ,To assess the antibacterial activity of propolis extracts from different agroecological zones against resistant bacterial strains and multidrug-resistant bacteria. ,To carry out a chemical profile of propolis from the different agroecological zones using spectroscopic and chromatographic techniques. ,To develop chemical profiles, determine antimicrobial activities, and formulate a nanobiotic of the Ugandan propolis obtained from various agroecological zones. ,
Uganda 2024-10-08 11:04:03 2027-10-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Sheila Ampaire
ID: UNCST-2021-R012468
Baseline Review of Safety Monitoring and Reporting in the conduct of clinical Trials in Uganda
REFNo: HS5028ES

2. To understand the barriers and facilitators of safety monitoring and reporting in clinical trials in Uganda.,1. To evaluate the safety reporting system in the conduct of clinical trials in Uganda.,
Uganda 2024-10-04 10:03:52 2027-10-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Ssekubugu
ID: UNCST-2019-R001365
Prevalence of Oral Human Papillomavirus and HIV-infection in priority populations in South Central Uganda: a pilot study
REFNo: HS4937ES

Objective 1: Estimate the prevalence of HIV and OHPV and their impact on oral health conditions in Rakai and neighboring districts in South Central Uganda.
(a) Estimate the prevalence of HIV and OHPV infection;
(b) Estimate the prevalence of oral diseases (pre-cancerous lesions, oropharyngeal cancer, periodontal disease, dental decay);
(c) Estimate the extent to which OHPV, HIV, and OHPV/HIV co-infection is associated with an increase in the prevalence of oral diseases.



Objective 2: Identify the barriers to accessing oral health services among fisherfolk participating in Rakai and neighboring districts in South Central Uganda.
a) Explore the key perceived barriers to healthcare services, including STI and oral health services;
b) Explore the level of oral health understanding among community members;
c) Explore the pathways community members use to access oral health care services,
d) Identify environmental, personal, sexual, and other risk factors associated with the prevalence of common oral conditions, including tooth decay, periodontal problems, and OHPV.

Uganda 2024-09-27 22:19:07 2027-09-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Micheal Mutyaba Raymond
ID:
END OF PROGRAM EVALUATION FOR THE CITY WIDE INCLUSIVE SANITATION PROGRAM
REFNo: SS3202ES

a) Assess progress and Impact: the study aims at evaluating the progress made by the CWIS project in achieving its stated objectives and assess the impact of project interventions on targeted communities and institutions. This will involve examining whether the project has effectively increased access to improved onsite sanitation services, particularly for underserved urban poor households, public institutions, and transient populations; and
b) Provide recommendations for future Interventions: Based on the evaluation findings, formulate actionable recommendations for future sanitation interventions in Kampala and neighboring municipalities. These recommendations will aim at enhancing the effectiveness, efficiency, and sustainability of sanitation service delivery, contributing to the broader goal of urban transformation and improved public health outcomes.

Uganda 2024-09-27 22:16:36 2027-09-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Vivian Najjuka NA
ID:
Health Information Seeking Behavior of People Living With Vitiligo in South Western Uganda
REFNo: SS3061ES

1. To establish the health information seeking practices for People Living with Vitiligo in South Western Uganda. 2. To determine the level of satisfaction with the health information sources by People Living with Vitiligo in South Western Uganda. 3. To identify the challenges encountered by People Living with Vitiligo in South Western Uganda, while seeking for health information on Vitiligo condition. 4. To explore interventions for enhancing health information access for coping with the Vitiligo condition in South Western Uganda.,The study seeks to explore the health information seeking behavior of People Living with Vitiligo in South Western Uganda and to propose interventions for enhancing HI access for coping with the Vitiligo condition.,
Uganda 2024-09-27 22:09:53 2027-09-27 Social Science and Humanities Non-Clinical Trial Degree Award
Mikiko Nihimura
ID:
Exploring “Actionable Information” for Learning Improvement in Rural East Africa: A Positive Deviance Approach
REFNo: SS3226ES

To explore effective channels of information sharing towards improving education outcomes at child, household, and school levels.,To understand how parents and schools obtain and use information for pupils’learning at home and school,To understand how parents and schools obtain and use information for pupils’learning at home and schoolto explore effective channels of information sharing towards improving education outcomes at child, household, and school levels.,
Japan 2024-09-27 22:07:58 2027-09-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
JAMES  SSENFUUMA THOMAS
ID: UNCST-2023-R005484
2REST Responsibilities for Resilience Embedded in Street Temporalities: mapping street youth lived resiliences through analysis of secondary data
REFNo: SS3217ES

To analyse the GUOTS data set using a multisystemic resilience framework to street life experiences


To explore the data set longitudinally using a breadth and depth approach to understand temporal changes in young people’s lives, across diverse urban contexts, for creating interventions that develop as young people grow up


To explore with stakeholders, how the analysed evidence base can support young street people and inform policy and practice across diverse African and global contexts
Uganda 2024-09-27 22:04:28 2027-09-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
SMART (Smallpox vaccine for Mpox Post-Exposure Prophylaxis: A Cluster Randomized Controlled Trial)
REFNo: HS4726ES

Co-Primary objectives Co-primary: 1) To assess the effectiveness of the Smallpox vaccine in preventing RT-PCR confirmed Mpox infection among contacts of confirmed Mpox infection 2) To assess the effectiveness of the Smallpox vaccine in reducing the severity of symptoms; measured as symptom severity score, based on 12 symptom items (16) each assigned a score of 0 to 5 for a total measure of 0 to 60. These co-primary objectives will be evaluated during the first 28 days after randomization.
Uganda 2024-09-27 14:06:23 2027-09-27 Medical and Health Sciences Clinical Trial Non-degree Award
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