Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Lawrence Okello Rafaih
ID:
Evaluation practices and strategy performance of local NGOs in Uganda
REFNo: SS1561ES

4. To determine the relationship between organizational evaluation steering process and strategy performance of NGOs in Uganda,3. To establish the relationship between organizational evaluation technical expertise and strategy performance of NGOs in Uganda,2. To determine the relationship between evaluation planning process and strategy performance of NGOs in Uganda,1. To validate the contextual relevance of organizational effectiveness competency model for strategy evaluation of NGOs in Uganda.,The purpose of this study is to validate the extent to which evaluation practices influence strategy performance of national NGOs in Uganda.,
Uganda 2022-12-19 12:19:45 2025-12-19 Social Science and Humanities Clinical Trial Degree Award
Daniella Ferguson
ID:
A Retrospective Analysis of Suramin Treatment forStage 1 Trypanosoma Brucei Rhodesiense Human African Trypanosomiasis (S1 TBR HAT) in Uganda and Malawi
REFNo: HS2582ES

Primary objectives
The primary objective is to determine whether standard of care treatment with suramin, as currently practiced in Uganda and Malawi, leads to better health outcomes in patients with S1 TBR HAT than observed in an untreated natural history cohort with source data from a published epidemiologic study.

Secondary objectives
The secondary objective is to evaluatethe safety and tolerability of suramin.

South Africa 2022-12-19 12:17:26 2025-12-19 Medical and Health Sciences Clinical Trial Non-degree Award
THOMAS EBOYU
ID:
COVID – 19 PANDEMIC ON ACCESS TO HEALTH CARE SERVICES AMONG PEOPLE LIVING WITH HIV/AIDS AT SOROTI REGIONAL REFERRAL HOSPITAL
REFNo: HS2579ES

iv. To determine the factors that have affected adherence to antiretroviral therapy by people living with HIV/AIDS, three months before and during the first total lockdown of COVID – 19 pandemic at Soroti regional referral hospital.,iii. To evaluate the views of the patients on accessibility, availability, affordability and acceptability of HIV/AIDS services, three months before and during the first total lockdown of COVID – 19 pandemic at Soroti regional referral hospital.,ii. To determine the trends of patients that continued attending for treatment of HIV/AIDS, three months before and during the first total lockdown of COVID – 19 pandemic at Soroti regional referral hospital.,i. To determine the trends of patients that have been diagnosed with HIV/AIDS, three months before and during the first total lockdown of COVID – 19 pandemic at Soroti regional referral hospital.,To determine the influence of COVID – 19 Pandemic on access to health care services and associated factors among people living with HIV/AIDS at Soroti regional referral hospital.,
Uganda 2022-12-19 12:15:58 2025-12-19 Medical and Health Sciences Non-Clinical Trial Degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
Factors associated with COVID19 misinformation and vaccine hesitancy in Ugandan communities
REFNo: HS2566ES

3. To explore the mechanisms of effect among factors that affect vaccine hesitancy and vaccine uptake at household level in Uganda.,2. To assess the factors associated with prevalence of COVID19 misinformation, COVID19 vaccine hesitancy, and COVID19 vaccine uptake at household level?,1. To determine the prevalence of COVID19 misinformation, COVID19 vaccine hesitancy, and COVID19 vaccine uptake at household level?,
Uganda 2022-12-19 12:03:01 2025-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samuel Kabbera
ID:
SUSTAINABLE PRACTICES, STAKEHOLDER ENGAGEMENT AND THE GROWTH OF SMALL AND MEDIUM AGRO-PROCESSING ENTERPRISES IN UGANDA.
REFNo: SS1301ES

Main Objective: To establish a link between sustainable practices, stakeholder engagement and the growth of SMEs in Uganda's agro-processing subsector. Specific Objectives: a) To examine the relationship between environmental sustainable practices and growth of agro-processing SMEs. b) To examine the relationship between social sustainable practices and growth of agro-processing SMEs. c) To assess the relationship between economic sustainable practices and growth of agro-processing SMEs. d) To investigate the mediating role of stakeholder engagement on the adoption of sustainable practices and the growth of agro-processing SMEs. e) To explore the experiences with the application of sustainable practices and growth in agro-processing SMEs in Uganda. f) To suggest a suitable sustainable framework that is applicable to a developing country context, with particular reference to Uganda that can predict the growth of agro-processing SMEs.
Uganda 2022-12-19 11:42:06 2025-12-19 Social Science and Humanities Non-Clinical Trial Degree Award
DAISY NABADDA
ID:
GENDER AND OTHER DETERMINANTS INFLUENCING THE EFFECTIVE RESPONSE, CONTROL, AND MANAGEMENT OF EBOLA VIRUS DISEASE IN UGANDA
REFNo: HS1176ES

i) Describe the community's level of knowledge, attitude, and perceptions (KAPs) of EVD in Uganda.
ii) Explore contextual factors affecting the effective response, control, and management of EVD in Uganda.
iii) Assess the gender relations in the access of treatment and control during EVD outbreaks.
iv) Describe the influence of myths, practices, and experiences of EVD affected communities in Uganda.
v) Examine how the performance of EVD response and control programs are influenced by policymakers at national, and community levels.


Uganda 2022-12-19 11:39:09 2025-12-19 Medical and Health Sciences Degree Award
Dan Kajungu
ID: UNCST-2019-R000786
Integrating Minimally Invasive Tissue Sampling (MITS) into the IMHDSS mortality-surveillance system for determining cause of death in children below 5 years of age
REFNo: HS2572ES

a) To identify and enumerate all under-5 deaths in the surveillance area
b) To determine cause of death using laboratory, histopathologic, clinical, maternal, and verbal autopsy data.
c) To obtain verbal autopsies and available maternal and infant clinical data on all eligible notified under-5 deaths in the site’s surveillance area and Eastern Uganda
d) To generate high quality cause-of-death data that informs policy and health actions
e) To build in-country capabilities and enable MITS Surveillance Alliance sites to leverage MITS investment to prevent under-5 child mortality.


Uganda 2022-12-14 14:22:30 2025-12-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fiona Atim -
ID: UNCST-2020-R015040
Primary Health Care Services and Health-Related Quality of Life Among Elderly Persons with Non-communicable Diseases in Uganda: The Case of Central Region
REFNo: SS1528ES

iii. To evaluate the mediating effects of home factors on health-related quality of life of the elderly persons with NCDs in selected districts in central Uganda.,ii. To assess the mediating effects of psychosocial support on the health-related quality of life of the elderly persons with NCDs in selected districts in central Uganda.,i. To analyze the effect of primary health care services on Health-related quality of life of elderly persons with NCDs in selected districts in central Uganda.,The main objective of this study is to investigate the influence of primary health care services on the HRQoL among elderly persons with NCDs in the central region of Uganda, to develop an intervention and a corresponding model to support the improvement of primary health care services and enhance HRQoL of the elderly persons.,
Uganda 2022-12-14 14:20:03 2025-12-14 Social Science and Humanities Non-Clinical Trial Degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
Automated smartphone-based cough audio classification for rapid tuberculosis triage testing (Cough Audio triaGE for TB; CAGE-TB)
REFNo: SS1536ES

To generate and separately validate a cough audio classifier that meets WHO triage test TPP sensitivity and specificity criteria.,
Uganda 2022-12-14 14:15:43 2025-12-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peter Ferrarone Timothy
ID:
Helping nurses overcome structural drivers of absenteeism in Uganda: A survey and discrete choice experiment
REFNo: HS2529ES

4.2 Objectives and research questions
1. To explore factors internal to the Ugandan health care sector that may be leading nurses to be absent from work
a) What job characteristics or conditions of employment are most influential in encouraging nurses / managers / midwives to not attend work?
b) Are there non-monetary job characteristics that are particularly important to nurses?
c) Are there substantial differences between nurses / managers / midwives that lead to differences in attendance and are there incentives to address these differences?
d) If so, does the effectiveness of interventions to overcome absenteeism vary according to these differences between nurses / managers / midwives?
e) Are there incentives encouraging nurses to be absent across the system and do these affect different groups of nurses / managers / midwives differently?
f) What effect, if any, does employment setting (urban versus rural) have on absenteeism and an individual’s decision to be absent?

2. To explore factors external to the Ugandan health care sector that may be leading nurses to be absent from work
a) What individual, social, structural, and contextual factors are most influential in encouraging nurses / managers / midwives not to attend work?
b) How do health worker characteristics influence service provider preferences in relation to incentives and other potential policy interventions to overcome absenteeism?
c) Are there substantial differences between nurses / managers / midwives that lead to differences in attendance and are there incentives to address these differences?
d) Does the effectiveness of interventions to overcome absenteeism vary according to these differences between nurses / managers / midwives?
e) Are there incentives encouraging nurses to be absent across the system and do these affect different groups of nurses / managers / midwives differently?
f) How does intrinsic and extrinsic motivation affect attendance at work?
g) What do health workers believe and perceive (from personal experience of word-of-mouth) is currently being done to combat absenteeism and what do they believe will be the most feasible policy solutions in the future?
3. To identify feasible policy interventions that are most likely to be taken up and impact behaviour
a) What are the experiences and perceptions of health care service providers of monetary and non-monetary incentives and other factors affecting service provider motivation and performance to inform the design of policy interventions to overcome absenteeism and ensure the delivery of quality health care services in Uganda?
b) Are there characteristics of health facilities that influence service provider preferences in relation to incentives and other potential policy interventions to overcome absenteeism?
c) What proportion of health workers would choose to attend work rather than be absent if presented with specific (hypothetical) job characteristics? How does this vary across the population?
d) What trade-offs, if any, are nurses willing to make between these attributes to identify the optimal combination of these factors for packages of policy interventions that can be implemented in light of local resource constraints to align the incentives facing frontline health care providers especially in rural settings to address the issue of absenteeism?
e) Are nurses / managers / midwives willing to trade between “carrot” and “stick” interventions to reduce absenteeism?
f) Is salary the main incentive? Are there non-monetary incentives that are likely to have an impact on nurse absenteeism?
g) What is the range of feasible and affordable policy interventions that are likely to be effective in addressing health worker absenteeism?
h) Is changing individual or group incentives likely to lead to less absenteeism?

USA 2022-12-14 14:10:49 2025-12-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Performance Evaluation of the Alinity m HIV-1 Assay using DBS
REFNo: HS2595ES

• To describe the operational characteristics and ease of use of the assays and their suitability for use in countries with limited infrastructure. ,• To assess the assay’s agreement with cobas HIV-1 Quantitative nucleic acid test for use on the cobas 6800/8800 Systems (Roche Diagnostics GmbH) on clinical specimens, including: o Quantitative assessment of bias, limits of agreement and correlation, o Misclassification above or below the clinical threshold;,The overall objective of the performance evaluation is to evaluate the performance and operational characteristics of Alinity m HIV-1 Assay (using DBS) intended for the quantification of HIV viral load in HIV-infected individuals.,
Uganda 2022-12-12 16:06:22 2025-12-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIET  NAKIGANDA
ID:
Private Sector Malaria Vector Control Scoping in Uganda: A Land Scape Analysis
REFNo: SS1512ES

To understand the public (consumers) perspectives and practices in accessing vector control commodities from the private sector, specifically (enter commodities),3. To identify the capacity and technical challenges that affect the quality of products and services of private sector vector control ,2. To map out the private sector supply chain systems of vector control products from importation to consumption in Uganda.,1. To understand the current regulations governing the quality and product range of imported and locally manufactured vector control commodities,To identify immediate and core gaps in the policies, access, supply, and use of malaria vector control interventions in the private sector so that the NMCD can channel focal interventions to increase access to quality vector control interventions in the private sector. ,
Uganda 2022-12-12 16:00:29 2025-12-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
KENNETH MUGABE
ID: UNCST-2022-R010732
Using lactate testing to improve maternal sepsis identification: a multi-country test accuracy study: LACTate in mATernal sEpsis
REFNo: HS2589ES

VI. Conduct a validation study of an alternative reference standard in which the SOFA score is modified to incorporate maternity specific ranges for creatinine and platelet concentration.,V. Exploratory analysis will examine the effect of adjusting the threshold values for both vital sign and lactate assessment on the sensitivity and specificity of the index tests.,IV. To explore if the test accuracy of lactate in addition to maternal vital sign monitoring alone varies by the pre-specified subgroups of pregnancy status (pregnant or post-delivery (including abortion or miscarriage)) and recruitment country.,III. To explore if baseline venous lactate, in addition to vital sign measurements, improves prediction of severe morbidity and mortality from infection.,II. To assess short-term predictive value of lactate testing, by comparing the baseline index test with 24-hour reference standard, in those without sepsis at baseline.,I. Immediate diagnostic value of lactate testing by comparing the baseline index test with baseline reference standard.,Determine the diagnostic accuracy of maternal venous lactate measurement in addition to maternal vital sign thresholds, in maternal sepsis in low-resource health facility settings in Malawi, Uganda and Pakistan.,
Uganda 2022-12-12 15:55:39 2025-12-12 Medical and Health Sciences Clinical Trial Non-degree Award
Amrei von Braun
ID:
RAPID SURVEILLANCE OF MOLECULAR MARKERS FOR ARTEMISININ RESISTANCE
REFNo: HS2546ES

To describe the type and prevalence of Plasmodium falciparum mutations conferring artemisinin resistance
Germany 2022-12-12 15:42:25 2025-12-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BEATRICE KATUSIIME
ID:
UNDERSTANDING THE COMMUNITY’S AND RESEARCH PARTICIPANTS’ PERCEPTIONS AND KNOWLEDGE OF VULNERABILITY IN RESEARCH: A QUALITATIVE STUDY IN UGANDA
REFNo: SS1495ES

3. To examine the determinants of vulnerability in health research conducted in Mbarara city,2. To explore the perception of research participants regarding vulnerability in health research in Mbarara city,1. To assess the community’s understanding of vulnerability in health research in Mbarara city,To describe community and research participants’ perceptions and knowledge of vulnerability in health research in Mbarara city,
Uganda 2022-12-12 15:32:51 2025-12-12 Social Science and Humanities Non-Clinical Trial Degree Award
YUKO NAKANO
ID:
How Effective is Formalization of Land Rental Agreement for Dispute Prevention? Evidence from Randomized Control Trial in Uganda’s Refugee Camp
REFNo: SS1540ES

To investigate if formal land rental agreement increase refugees’ income,To investigate if the access to the land rental market increased by the formalization of land rental transactions,To investigate if formal land rental agreement reduce conflicts between refugees and local Ugandans,
Japan 2022-12-12 15:26:49 2025-12-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Performance Evaluation of the Alinity m HIV-1 Assay using DBS for Detection of HIV-1 in Infants.
REFNo: HS2586ES

To verify the performance (sensitivity and specificity) of the Alinity m HIV-1 Qualitative Test against routine Cobas Ampliprep/Taqman HIV-1 Qualitative Test Version 2.0 (DBS)- for early diagnosis of HIV-1 in exposed infants. ,
Uganda 2022-12-12 15:23:01 2025-12-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brian Kiira Alex
ID:
Emerging Ethics and Human Rights Issues in the Digitization of Population Register Systems
REFNo: SS1383ES

1. To nurture a new generation of scholars and practitioners via direct mentoring from senior scholars and experienced practitioners in the field, immersion into academic, policy and practitioner networks, debates and institutions, exposure and visibility through publications and communications based in the global South. 2. To support active collaboration between fellows as well as between IUSSP, WiSER, ISER and IIGH-USC. 3. To nurture a generation of scholars who will challenge experienced practitioners, senior scholars and established systems to consider new perspectives, rethink established assumptions and question dominant paradigms for population register systems. 4. To facilitate stronger engagement by population scientists on contemporary issues and support interdisciplinary collaboration with established scholars from other disciplines and early career researchers and practitioners around ethics and human rights in the digitization of population register systems.
Uganda 2022-12-09 12:35:52 2025-12-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
FRED SEMITALA COLLINS
ID: UNCST-2020-R014096
Differentiated Services Delivery Outcomes in Uganda: Facilitators, barriers, and qualitative systems mapping.
REFNo: HS2497ES

To evaluate the performance and quality of DSD models in the delivery of HIV/TB services in Uganda.
Specific Objectives:
1. To assess the performance and Quality of intensive and less intensive DSD models of care for HIV/TB TB services in Uganda.
2. To elicit stakeholders’ perspectives on facilitators of and barriers to improved DSD performance in Uganda.

3. To identify system elements (systems mapping) and determine how their relationships in health care affect both positively and negatively the performance of DSD service delivery in Uganda.

Uganda 2022-12-08 15:05:56 2025-12-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Mafigiri Kaawa
ID: UNCST-2019-R001276
Rapid Anthropological Study in Districts Affected by Ebola (Sudan Strain) in Uganda
REFNo: SS1542ES

The general objective of this study is to explore the socio-cultural construction of the drivers of the current Ebola virus disease (EBV) transmission and community resistance to Ebola response strategies in Uganda
Uganda 2022-12-08 13:08:41 2025-12-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
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