Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Sarah Lewinger Julianne
ID: UNCST-2024-R004045
 Prayer, Poetry, and Protest: Pentecostalism and Political imagination among Ugandan Youth
REFNo: SS2594ES

The primary objective of this research project is to investigate how young people in Kampala, Uganda, aged eighteen to thirty-five, mobilize charismatic Christian discourses, practices, and communities to imagine their futures, engage with politics, and navigate conditions of political repression, economic precarity, and social disintegration. Specifically, the project aims to:
1. Explore the diverse ways in which young people draw upon charismatic Christianity as a resource for making sense of their lives, asserting their dignity, and envisioning alternative social and political possibilities.
2. Examine how young people's "god-talk" – a critical and creative method of biblical reinterpretation and intimate conversation with the divine – challenges conventional understandings of the political and expands notions of political agency and engagement.
3. Investigate the role of social memory in shaping contemporary youth political imaginations, by considering how young people's religious-political expressions both draw upon and depart from earlier movements, such as the Holy Spirit Movement.
4. Identify and analyze the spaces, practices, and cultural forms through which young people develop and express their political subjectivities, with a focus on artistic and creative practices, such as spoken word poetry and music.
5. Contribute to anthropological debates on the complex and often contradictory role of religion in social movements, as well as the ways in which marginalized youth navigate and challenge the constraints of their political contexts.
This project aims to generate new insights into the religious and political imaginations of urban Ugandan youth, and to shed light on the diverse and unexpected ways in which young people are actively engaging with politics outside of the formal political sphere. By taking seriously the political significance of religious and artistic imaginaries, this research has the potential to expand our understanding of what constitutes the political and to contribute to broader debates about youth agency, social movements, and the role of religion in public life.
USA 2024-12-10 14:52:31 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
PREETI KUMARI
ID: UNCST-2024-R001852
 Science Laboratory Operationalization, Secondary School Students’ Academic Attitude, Motivation, and Performance in Mbarara City, Uganda
REFNo: SS3434ES

1. To assess the conditions of science laboratories in secondary schools in Mbarara City, Uganda, to get a ground-level reality check.
2. To examine the relation between science laboratory operationalization and student’s attitude towards science.
3. To investigate the effect of science laboratory operationalization on motivation in choosing science as a career.
4. To relate the science laboratory operational conditions to students' performance in science education.
5. To study the mediation effect of student’s attitude and motivation in science subjects on performance.

 India 2024-12-10 14:47:47 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
sandra etumah omon
ID: UNCST-2024-R003992
 Assessment of the Nutritional Profile and Biochemical Adaptation of Zea mays L. Grown around Kilembe Mining Area, Kasese, Uganda
REFNo: NS809ES

1. To assess the Physicochemical characteristics of the soil and heavy metal content such as copper, lead, cobalt, Nickel, Cadmium, Mercury, chromium, and arsenic at the research site.
2. To analyze the heavy metals content (copper, lead, cobalt, Nickel, Cadmium, Mercury, chromium, and arsenic) of the maize plant grown at the mining site and their translocation.
3. To analyze the nutritional profile: proximate analysis (carbohydrates, protein, fats/oil, crude fiber, moisture, and ash), mineral element (iron, magnesium, manganese, calcium, sodium, phosphorus, sulfur, and potassium), and Vitamins (thiamine, niacin, riboflavin, retinol, cobalamin, pyridoxine, tocopherol, ascorbic acid, and cholecalciferol) of the maize grown around the mining site.
4. To assess the oxidative stress markers (malondialdehyde, tocopherol, and proline) and the enzymatic antioxidant capacity (glutathione peroxidase, superoxide dismutase, and catalase) in the leaves during the vegetative stage of the maize plant.
5. To quantitatively determine the hormonal levels (ABA, auxins, and brassinosteroids) in the leaves during the vegetative stage of the maize
6. To determine bioremediation options from the culturable rhizospheric soil bacteria isolated from around the mining site.

 Nigeria 2024-12-10 14:44:20 2027-12-10 Natural Sciences Non-Clinical Trial Degree Award
Maria Magdalene Namaganda
ID: UNCST-2021-R004319
 Development of a machine learning model for prediction of virological failure in a resource-limited setting
REFNo: HS3982ES

Sub-study 1 To identify the risk factors associated with virological failure among PLWH in east Africa from 2014 to 2024. Sub-study 2 To analyse the trends of ART use and incidence of virological failure rates among PLWH in TASO-Uganda health centres from 2014 to 2024. Sub-study 3 To develop and validate machine learning models for prediction of virological failure. Sub-study 4 To evaluate the practical utility of the HIV virological failure predictive models developed in a clinical setting.
Uganda 2024-12-10 14:40:45 2027-12-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Jackson Orem
ID: UNCST-2021-R012016
 A Phase III, Randomized, Open-Label, Non-Inferiority Study of Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma in Resource-Limited Settings
REFNo: HS4073ES

To describe the incremental cost-effectiveness ratio per QALY gained (as assessed by PROPr) between PLD and PTX,To assess quality of life across PROMIS domains (i.e., cognitive function, physical function, fatigue, pain interference, depressive symptoms, anxiety, ability to participate in social roles and activities, and sleep disturbance) with the PROPr tool at start of therapy, mid-treatment, and after treatment with PLD and PTX ,To describe the cost of therapy across AMC sites in sub-Saharan Africa to deliver both PLD and PTX by micro-costing analysis for goods and time-in-motion analysis for services. ,To estimate the objective response rate (defined as the sum of complete and partial responses) for AIDS-KS, response duration and overall survival in each treatment arm. ,To evaluate whether there is sufficient evidence to conclude that PLD is non-inferior to PTX in people with severe AIDS-associated KS receiving concomitant ART in resource-limited settings. ,
 Uganda 2024-12-10 14:39:24 2027-12-10 Medical and Health Sciences Clinical Trial Non-degree Award
Adelline Twimukye
ID: UNCST-2019-R000117
 HIV CARE AND ANTENATAL HEALTH SEEKING BEHAVIOUR PATTERNS OF PREGNANT AND BREAST-FEEDING WOMEN DURING PREVIOUS COVID-19 PANDEMIC IN UGANDA
REFNo: SS3219ES

To document the challenges faced by pregnant and breastfeeding women with HIV in accessing healthcare services in the COVID-19 period.,To interrogate the effects of COVID-19 pandemic to adherence to routine clinic appointments and antiretroviral therapy (ART) among pregnant and breast-feeding women living with HIV.,To examine the social or cultural norms that influence access to care among pregnant or breast-feeding women HIV during the COVID-19 pandemic.,To investigate health care worker’s knowledge, attitude, and practices about COVID-19 among pregnant and breast-feeding women living with HIV in Uganda.,The purpose of the study is to explore HIV care and antenatal seeking behavior patterns of pregnant and breast-feeding women during response and control of COVID-19 pandemic in Uganda.,
 Uganda 2024-12-10 14:37:39 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
VICENT MWESIGYE
ID: UNCST-2024-R002866
 LYMPHEDEMA: CAUSATIVE AGENTS, PATIENT AND CARETAKER KNOWLEDGE, SELF-REPORTED HEALTHCARE NEEDS AND PREVENTIVE STRATEGIES IN KAMWENGE DISTRICT.
REFNo: HS5335ES

3. To explore the lymphedema-related knowledge, lived experiences and healthcare needs of patients and their caretakers and preventive strategies in Kamwenge district, South Western Uganda.,2. To determine the causative agents of lymphedema among patients with lymphedema in Kamwenge district, South Western Uganda.,1. To describe the Preventive strategies, their effectiveness in patients with Lymphedema based on Scoping review globally.,To determine the causative agents, patient and caretaker knowledge, self-reported healthcare needs and preventive strategies amongst Lymphedema patients in Kamwenge District South Western Uganda.,
 Uganda 2024-12-10 14:35:45 2027-12-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Tess Lallemant
ID: UNCST-2023-R007159
 How do Firms Hire? A Demand-Side Experiment to Reduce Matching Frictions in Uganda Labor Markets
REFNo: SS3487ES

1. Answer the research question: How do firms navigate the hiring process for graduate workers?
2. Answer the research question: How are firms identifying their employment needs?
3. Answer the research question: How are firms communicating their employment needs?
4. Answer the research question: To what extent are these hiring frictions affecting match quality?
5. Answer the research question: Do firms learn about hiring and adapt their search strategies to achieve higher match quality?
 USA 2024-12-10 14:24:53 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Optimizing the Implementation and Scale-Up of the WHO Treatment-Decision Algorithms for Children with Pulmonary Tuberculosis in Sub-Saharan Africa (OPTIC-TB)
REFNo: HS5246ES

1) To compare the effectiveness of TDA versus the Standard of Care strategies in routine non-research programmatic conditions.
2) To identify processes and contextual factors that influence the effectiveness and fidelity in the implementation of TDA.
3) To compare the costs, cost-effectiveness, and population-level impact of the TDA strategies on the burden of TB.
4. To estimate/validate the diagnostic performance (sensitivity, specificity, negative and positive predictive values) of the TDAs for TB in children under 10 years old in various healthcare system settings and in various clinical contexts (i.e, such as HIV, malnourished children, facility level, gender, rural, urban etc.

Uganda 2024-12-10 14:06:31 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Vianney Tushabe John
ID: UNCST-2024-R015708
 Development of Multiplex Molecular Test for S. mansoni and P. falciparum Duplex using LAMP assay and Pit Latrine metagenomic sampling for community assessment
REFNo: SIR445ES

- Development of the Multiplex Malaria – Schistosomiasis assay
- Latrine Metagenomics for community diagnostics assessment 
- Validation of Molecular duplex assay technology 
 Uganda 2024-12-10 14:04:09 2027-12-10 Engineering and Technology Non-Clinical Trial Degree Award
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