Joseph Ngonzi
ID: UNCST-2019-R001579
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OPTIMIZATION, VALIDATION AND ASSESSMENT OF FEASIBILITY AND ACCEPTABILITY OF HPV TESTING USING CODA
REFNo: HS4734ES
To develop and establish a novel rapid multi-modal algorithm (CANOPY) for screening and treatment of cervical cancer integrating multiple (CODA, VIA, ML) screening modalities to improve diagnostic yield. ,To gather design feedback to improve CODA workflow and device design, and refine CODA device, assay, and workflow using this critical feedback provided by Ugandan stakeholders,To evaluate the feasibility and acceptability of CODA in a clinical setting in Uganda based on feedback from clinical, public health, and patient stakeholders,To evaluate HPV testing using CODA in comparison to other (VIA, ML, ATILA System) devices for clinicians and patients engaged in community-based cervical cancer screening. ,To determine the diagnostic accuracy of CODA a clinical setting, using FP rate and comparison with gold-standard HPV tests and cytology,We will optimize, validate and assess the feasibility and acceptability of HPV testing using CODA and develop and validate a multimodal cervical cancer screening algorithm to optimize diagnostic yield (CANOPY).,
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Uganda |
2024-12-10 15:49:00 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Anxious Niwaha Jackson.
ID: UNCST-2023-R008010
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Investigating the pancreas pathology underlying Lean Sub Saharan African
Diabetes in Uganda
REFNo: HS5340ES
a. To compare the beta cell mass in pancreata obtained at autopsy in lean diabetes cases
versus lean controls
b. To evaluate the degree of pancreatic immune infiltration (Insulitis) in lean diabetes cases
and lean controls
c. To quantify the degree of misfolded protein stress in pancreata obtained at autopsy in lean
diabetes cases and lean controls
d. To evaluate beta cell dedifferentiation in lean SSA diabetes
e. To examine the exocrine pancreas for chronic pancreatitis and pancreatic duct calcification
in pancreata obtained at autopsy in lean diabetes cases versus lean controls
f. To determine the concentration of POPs in pancreata obtained at autopsy in lean diabetes
cases and lean controls.
g. To establish a pancreata and related tissue (blood and mesenteric fat) platform to enable
further studies related to diabetes and other metabolic diseases.
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Uganda |
2024-12-10 15:47:20 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Nixon Niyonzima
ID: UNCST-2020-R014577
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Implementation and evaluation of peer support and navigation supported by Project ECHO for patients with cancer in Uganda
REFNo: HS5297ES
6. To evaluated perceived program feasibility, acceptability, and appropriateness through surveys and exit in-depth interviews with peer navigators, patients, and UCI oncologists,5. To adapt the Cancer Behavior Inventory (CBI-B) self-efficacy scale, Edmondton Symptom Assessment Scale (ESAS), and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 (EORTC QLQ C30) quality of life for cancer patients questionnaire to the Uganda context by soliciting feedback from UWOCASO members and UCI oncology and palliative care specialists,4. To evaluate program impact by measuring patient self-efficacy, symptom burden, and quality of life using the above adapted scales at enrollment, 1, 3, 4 and 6 months after the program start ,3. To evaluate program impact by comparing the proportion of patients who completed treatment for early stage disease and or had treatment adherence of > 6 months in case of metastatic disease among patients matched with peer support and navigation right away versus six months later. ,2. To pair 100 cancer survivors with 200 matched patients with cancer in the Kampala, Wakiso, and Gulu districts of Uganda for peer support and navigation. Half of the selected patients will be randomized to be matched to peer support immediately, and half six months later . ,1. To provide refresher training in peer support and navigation to 100 cancer survivors. We will focus on the five most common cancers in Uganda (breast, cervical, prostate, Kaposi sarcoma, Non-Hodgkin lymphoma).,
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Uganda |
2024-12-10 15:46:22 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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ELIZABETH KYAZIKE
ID: UNCST-2023-R005557
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The Lasting Scars of War: Understanding the Socio-environmental Impact of Changing Global Commodity Chains in East Africa During the Second World War, 1937-1962
REFNo: SS3146ES
General Objective
The project's general objective is to document the impact of World War II on the Lake Victoria-area environment in the immediate (wartime) and midterm (into the post-war period) periods.
Specific Objective
Specifically, the project seeks to:
1) Evaluate the changes in environmental patterns of use (agricultural use, resource extraction, etc.) during the Second World War and its socio-environmental impacts.
2) Examine how the linkages between Africa (affected population), Great Britain (colonial power and prosecutor of war) and Switzerland (experts and trading companies) drove environmental change.
3) Analyze how global patterns were evident in the Lake Victoria region, in particular in relation to sustainable practices and cultures.
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Uganda |
2024-12-10 15:43:59 |
2027-12-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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DANIEL KIIZA
ID: UNCST-2024-R004044
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Development and Validation of a Machine Learning Prediction Model for Early Mortality among patients with HIV-Associated Cryptococcal Meningitis in Uganda
REFNo: HS5103ES
Primary Objectives:
1. To develop a machine learning model for the prediction of early mortality among patients with HIV-CM co-infection.
2. To validate a machine learning model for the prediction of early mortality among patients with HIV-CM co-infection.
Exploratory Objective:
3. To develop and validate a machine learning model for the prediction of mortality (as a continuous outcome) among patients with HIV-CM co-infection.
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Uganda |
2024-12-10 15:42:48 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Silvia Awor
ID: UNCST-2019-R000591
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PREDICTORS OF USE, PHYTOCHEMICAL PROFILES AND ANTISICKLING ACTIVITIES OF HERBAL MEDICINES FOR TREATING SICKLE CELL DISEASE IN ACHOLI SUB-REGION
REFNo: HS5030ES
2. To document the herbal medicines used for treating sickle cell disease in AchTo determine the anti-sickling activity of aqueous crude extracts of herbal medicines for sickle cell treatment in the Acholi sub-region. ,To assess the phytochemical profiles of selected herbal medicines used for the treatment of sickle cell disease in Acholi sub-region,To document the herbal medicines used for treating sickle cell disease in Acholi sub-region,To determine the predictors of the use of herbal medicines for the treatment of sickle cell disease in Acholi sub-region,To assess the predictors of use and antisickling activities of herbal medicines used for treating sickle cell disease in the Acholi sub-region of northern Uganda,
|
Uganda |
2024-12-10 15:41:38 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Abbas Mugisha
ID: UNCST-2023-R007013
|
Internally displaced persons and psychosocial challenges of females at Muhokya IDP, Kasese district, Ugands
REFNo: SS3392ES
i)To identify the psychosocial challenges experienced by internally displaced females at Muhokya IDP camp
ii)To explore the coping mechanisms employed by internally displaced females to manage the psychosocial challenges at Muhokya IDP camp
iii)To explore the redress mechanisms available for the psychosocial challenges faced by internally displaced females at Muhokya IDP camp
iv)To propose recommendations on how to best assist internally displaced females overcome their challenges at Muhokya IDP camp
|
Uganda |
2024-12-10 15:26:35 |
2027-12-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
ARTHUR EMORU
ID: UNCST-2024-R003421
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PREVALENCE AND FACTORS ASSOCIATED WITH CHRONIC POST-SURGICAL PAIN AMONG PATIENTS THAT RECEIVED AMBULATORY INGUINAL HERNIA SURGERY AT KYABIRWA SURGICAL CENTER
REFNo: HS5068ES
To determine factors associated with chronic pain after inguinal hernia repair among adult patients at Kyabirwa Surgical Center,To assess the prevalence of chronic pain after inguinal hernia repair among adult patients at Kyabirwa Surgical Center,To determine the prevalence of and factors associated with chronic pain after inguinal hernia repair in Kyabirwa Surgical Center’s adult patient population,
|
Uganda |
2024-12-10 15:25:15 |
2027-12-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Orace David Tom
ID: UNCST-2024-R003113
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Students’ Loan Financing Scheme and Completion of STEM based Programmes in Public Universities in Uganda
REFNo: SS3353ES
i). To explore the nature of students’ loan financing scheme in public universities in Uganda
ii). To assess the completion of STEM based programmes by students on loans scheme in public universities in Uganda
iii). To evaluate the perceptions and experiences of STEM students regarding the impact of students’ loan scheme on their completion in public universities in Uganda
iv). To establish the relationship between students’ loan financing scheme and completion of STEM based programmes in public universities in Uganda
|
Uganda |
2024-12-10 15:23:45 |
2027-12-10 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Stevens Bechange
ID: UNCST-2022-R009190
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Understanding Access to Business Financing for Young Entrepreneurs with and without Disabilities in Urban Uganda
REFNo: SS3471ES
The specific objectives will be:
1. To identify the different types of business financing options accessible by and preferred by young enterpreneurs with and without disabilities including what drives them to use these options.
2. To understand existing barriers for young enterpreneurs with and without disabilities in accessing and using the different business financing products, what can be done to address these and recommendations for more widespread access.
3. To describe how financial products from the RISE/E Programme affect young enterpreneurs with and without disabilities and their businesses and how they can be further improved.
4. Develop a database that includes demographic, socio-economic; and business financing information to facilitate the evaluation of success or failure with access to finance.
|
Uganda |
2024-12-10 15:17:09 |
2027-12-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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