Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Winnie Nakatudde
ID: UNCST-2025-R018763
Understanding Refugee Voices: Refugee Girls Experiences with Uganda’s Education Policies.
REFNo: SS3950ES

• To understand the extent to which Uganda’s current education policies and initiatives effectively meet refugee girls’ heterogeneous aspirations and needs.
• To find out how refugee girls in Nakivale settlement navigate educational trajectories, considering their gender, ethnicity, and social backgrounds.
• To examine the extent to which refugee girls in Nakivale settlement draw on and pursue ecological support systems (family, community, NGOs) to aid their educational integration.
• To determine how the lived experiences of refugee girls in Nakivale settlement differ from those of refugees in an urban setting.
Uganda 2025-06-20 18:50:23 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
Denis Kimbugwe
ID: UNCST-2025-R017664
Systemic inflammation in pregnant and postpartum mothers with HIV and their children: relationship with early child growth (SIPPH Study).
REFNo: HS6041ES

1. Evaluate the association of second trimester maternal inflammatory markers with CHEU growth patterns from birth through 2 years.
2. Evaluate the association of maternal inflammatory markers during first 2 months postpartum with CHEU growth patterns from birth through 2 years.
3. Evaluate the association of CHEU inflammatory markers at birth with growth patterns from birth through 2 years.
Uganda 2025-06-20 18:38:43 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Kajjimu
ID: UNCST-2021-R013696
Emergency Care Research in Uganda: Priorities, Barriers, and Strategies
REFNo: HS5847ES

To identify research priorities, evaluate existing barriers, and propose interventional strategies for enhancing emergency care research in Uganda. ,
Uganda 2025-06-20 18:32:38 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Maxson Anyolitho Kenneth
ID: UNCST-2021-R013447
Enhancing Integration of Adolescent Family Planning and Post-Abortion Care in Northern Uganda: A Citizen Science, Gender-Transformative Approach (CAFFP-PAC)
REFNo: HS6030ES

5. To document and disseminate best practices and lessons learned from implementing the integrated CAFFP-PAC using a citizen science gender-transformative approach in Lira, Northern Uganda.,4. To evaluate the effectiveness of an integrated CAFFP-PAC using a citizen science gender-transformative program to improve access to, and utilization of family planning and post-abortion care services in Lira, Northern Uganda.,3. To co-design and implement an integrated CAFFP-PAC using a citizen science gender-transformative approach to improve access to, and utilization of SRH services in Lira, Northern Uganda.,2. To engage citizen scientists in identifying barriers to and facilitators for accessing and utilizing family planning and post-abortion care services in Lira, Northern Uganda.,1. To assess the baseline knowledge, attitude, and practices of adolescents regarding family planning and post-abortion care in Lira, Northern Uganda.,To improve access to, and utilization of SRH services by female and male adolescents and other underserved population groups in Lira, Northern Uganda through an integrated CAFFP-PAC using a citizen science gender transformative approach (CS-GTA).,
Uganda 2025-06-18 20:27:59 2028-06-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samantha Agasha
ID: UNCST-2025-R017839
Exploring Sexual and Gender-Based Violence Against Women in Sports in Uganda: Causes, Impacts, and Interventions
REFNo: SS3892ES

Primary Objective: To explore the prevalence, causes, impacts, and interventions related to sexual and gender-based violence against women in sports in Uganda. Specific Objectives: • To assess the prevalence and forms of SGBV in Ugandan sports. • To examine the underlying causes and contributing factors of SGBV within sports institutions. • To investigate the psychological, physical, and socio-economic impacts of SGBV on women athletes. • To evaluate the effectiveness of existing interventions and support mechanisms aimed at addressing SGBV in sports.
Uganda 2025-06-17 15:52:19 2028-06-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Esther Kataate Namakula
ID: UNCST-2025-R016688
A Study of Pedagogical Content Knowledge in Action: Exploring Gender Inclusive Practices in Physics Education in the context of Uganda
REFNo: SS3925ES

The study seeks to understand how Physics teacher educators in Uganda draw from their Pedagogical Content Knowledge (PCK) to incorporate gender-inclusive practices in their teaching, shaping the development of preservice teachers. The ultimate goal is to understand how PCK and gender-inclusive practices of Physics Teacher educators can support preservice teachers in fostering more inclusive and equitable Physics classrooms, thereby encouraging more girls to pursue the subject.
Uganda 2025-06-12 9:27:13 2028-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
Bienvenu Akowedaho Dagoudo
ID: UNCST-2025-R018501
Women’s entrepreneurship and Participatory Guarantee System for agroecology and sustainable food system in Uganda
REFNo: A597ES

The objective of the research aims to evaluate women’s entrepreneurship and participatory guarantee system for agroecology foods systems in Uganda

In order to achieve the main research objective, four specific objectives have been elaborated.
• To analyze the relationship between organic farming and agroecology in Uganda;
• To evaluate organic farming efficiency in relation to agroecological approaches in Uganda;
• To assess women entrepreneurship eco-efficient organic farming in relation to agroecology and sustainable food systems in Uganda;
• To analyze participatory guarantee systems for organic certification in the agroecological perspective in Uganda.
Benin 2025-06-12 9:22:00 2028-06-12 Agricultural Sciences Non-Clinical Trial Degree Award
Brenda Simbwa Nakafeero
ID:
Study title: HPV vaccination uptake, drop-out rate and associated factors among female adolescents in Wakiso district, Uganda
REFNo: HS5168ES

To determine uptake of HPV vaccination among female adolescents in Wakiso district, Uganda.
To determine drop-out rate of HPV vaccination among female adolescents in Wakiso district, Uganda.
To determine the factors associated to HPV vaccination uptake among female adolescents in Wakiso district, Uganda.
To determine the factors associated to drop-out rate of HPV vaccination among female adolescents in Wakiso district, Uganda.
To assess the knowledge and attitudes of female adolescents, parents, and healthcare providers towards the HPV vaccine in Wakiso, Uganda.

Uganda 2025-06-12 9:20:51 2028-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRANCIS TAMALE
ID: UNCST-2025-R018057
Institutional Quality, the Macroeconomy and Tax Revenue Growth in Uganda
REFNo: SS3891ES

To evaluate how institutional quality and macroeconomic factors jointly influence tax revenue growth in Uganda, and to assess the mediating role of tax compliance in these relationships
Uganda 2025-06-12 14:30:49 2028-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
JOAN ATURINDA
ID: UNCST-2025-R017847
BUSINESS PROCESS REENGINEERING AND ORGANISATIONAL PERFORMANCE OF SMALL AND MEDIUM ENTERPRISES IN MBARARA CITY AND BUSHENYI DISTRICT.
REFNo: SS3878ES

The general objective of this study is to investigate the relationship between business process reengineering and organisational performance of SMEs. specific objectives; To examine the effect of information technology capabilities on organisational performance of SMEs. To examine the relationship between organisational structure and organisational performance of SMEs. To determine the relationship between organisational readiness for change and organisational performance of SMEs. To measure the moderation effect of ownership on the relationship between business process reengineering and organisational performance of SMEs.
Uganda 2025-06-12 14:28:19 2028-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
John Semazzi Baptist
ID: UNCST-2025-R016637
Elucidating Agroforestry Practices' Influence on Smallholder On-farm Species Diversity and Food Security in Rakai and Kitgum Districts of Uganda
REFNo: SS3882ES

General objective: To generate knowledge on the contributions of agroforestry practices to smallholder on-farm species diversity and food security among smallholder farmers in Rakai and Kitgum districts of Uganda Specific objectives: 1.To assess the level of adoption of agroforestry practices among smallholder farmers in Rakai and Kitgum districts. 2. To examine the contribution of agroforestry practices to household food security in Rakai and Kitgum districts. 3. To identify the factors underpinning adoption of agroforestry practices among smallholder farmers in Rakai and Kitgum districts. 4. To investigate the effect of agroforestry practices on on-farm species diversity in Rakai and Kitgum districts.
Uganda 2025-06-12 14:26:39 2028-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
Samuel Balamaga Ssanyu
ID: UNCST-2023-R005693
ADOLESCENT RISKY SEXUAL BEHAVIORS, EFFECT OF PEER-LED SEXUALITY EDUCATION, AND SECONDARY SCHOOL PREPAREDNESS FOR THE SEXUALITY EDUCATION NEEDS OF ADOLESCENTS IN MASAKA CITY
REFNo: HS5938ES

3. To examine the preparedness of secondary schools to respond to the sexuality education needs of school-going adolescents in Masaka City, Uganda.,2. To evaluate the effect of peer-led sexuality education on the sexual behaviors of adolescents attending secondary schools in Masaka City, Uganda.,1. To determine the prevalence of risky sexual behaviors and associated factors among adolescents attending secondary schools in Masaka City, Uganda., To determine the prevalence of risky sexual behaviors, the effect of peer-led sexuality education, and the preparedness of secondary schools in Masaka City, Uganda to respond to the sexuality education needs of school-going adolescents.,
Uganda 2025-06-10 14:35:14 2028-06-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
Performance evaluation of the Truenat® MPX Tests to detect Mpox in Uganda
REFNo: HS5956ES

1) To compare the sensitivity and specificity of the Truenat® MPX assay with BioPerfectus Monkeypox Virus Real Time PCR Kit / Altona Fexstar in detecting Mpox cases in Uganda.
2) To assess the overall diagnostic accuracy, including the rate of false positives and negatives, of the Truenat® MPX assay compared to the RT-PCR standard.
Uganda 2025-06-10 14:33:48 2028-06-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mark Kaddu
ID: UNCST-2025-R017147
IMPACT OF ELECTRONIC LOGISTICS MANAGEMENT INFORMATION SYSTEM (eLMIS) ADOPTION AND UTILIZATION ON SUPPLY CHAIN PERFORMANCE IN PUBLIC HEALTH FACILITIES IN GREATER KAMPALA METROPOLITAN AREA.
REFNo: HS5793ES

General Objective To assess the impact of eLMIS adoption and utilization on the performance of health supply chains in public health facilities in Greater Kampala Metropolitan Area Specific Objectives 1. To determine the level of adoption and utilization of eLMIS in public health facilities in Greater Kampala Metropolitan Area. 2. To investigate the impact of eLMIS adoption and utilisation on health supply chain key performance indicators in Greater Kampala Metropolitan Area public health facilities.
Uganda 2025-06-05 9:11:13 2028-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Barbara Castelnuovo
ID: UNCST-2019-R000802
HEALTHy aging with HIV in Uganda cohort: screening for non-communicable diseases and geriatric syndromes. (HEALTHiv)
REFNo: HS5803ES

Specific Aim 1. To document endpoints of NCDs (and their risk factors) that are common in older PLWH exposed to the currently recommended ART regimens, particularly cardio vascular disease, renal disease (proteinuria and creatinine clearance), metabolic syndromes and bone loss (calcaneal ultrasound) and their risk factors.
Specific Aim 2. To document frailty and other geriatric syndromes in older PLWH, frailty and geriatric syndromes progression and risk factors
Uganda 2025-06-05 9:08:20 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Maren Mickeler
ID: UNCST-2024-R003691
Understanding supportive leadership in organizations
REFNo: SS3820ES

This study investigates how supportive leadership influences bottom-up knowledge sharing within organizations. Although frontline employees often have valuable insights, their knowledge frequently fails to reach upper management—often due to supervisory barriers such as strict hierarchies, micromanagement, or a lack of psychological safety.

To address this, the research team is conducting a randomized controlled trial (RCT) in collaboration with Centenary Bank Uganda. The intervention involves providing supportive leadership training to supervisors (middle managers) in randomly selected bank branches. Control branches will not receive the training during the study period.

Our main objective therefore is to test and measure the effect of supportive leadership training on bottom-up knowledge sharing and other organizational outcomes in a real-world organizational setting.
Germany 2025-06-05 8:57:07 2028-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paul Mwanja
ID: UNCST-2024-R002501
ADMINISTRATIVE VARIABLES AND DISCIPLINE OF ACADEMIC STAFF IN PUBLIC UNIVERSITIES IN KAMPALA, UGANDA
REFNo: SS3830ES

i. To investigate the relationship between staffing and academic staff discipline in public universities in Kampala, Uganda.
ii. To examine the relationship between organizing and academic staff discipline in public universities in Kampala, Uganda.
iii. To analyse the relationship between directing and academic staff discipline in public universities in Kampala, Uganda.
iv. To assess the relationship between control and academic staff discipline in public universities in Kampala, Uganda.
v. To investigate the relationship between the intervening variables and academic staff discipline in public universities in Kampala, Uganda

Uganda 2025-06-05 8:55:27 2028-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
A workshop-based learning for Medical Officers, Senior House Officers, Psychiatrists, and Pediatricians (Medical Doctors) in the use of medication in treating child and adolescent mental health conditions in Uganda.
REFNo: HS5877ES

Main Objective
1. To assess the current level of knowledge, skills, and practice of prescribing medications to address children and adolescents’ mental health conditions among medical doctors in Eastern Uganda.
2. To develop, evaluate and administer a workshop-based training materials on the use of medication in treating child and adolescent mental health conditions in Eastern Uganda.
Specific Objectives
1. To explore the knowledge, skills and practices of medical doctors regarding use of medications in treating child and adolescent mental health conditions in Eastern Uganda.
2. To develop and implement a workshop-based training for 50 medical doctors working with children and adolescents in Eastern Uganda.
3. To conduct an evaluation of the training programme among the medical doctors.
Uganda 2025-06-05 8:49:35 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
Cluster randomized trial of intermittent preventive treatment of malaria in school-age children to improve the health of students and decrease community transmission (CRITICal)
REFNo: HS5878ES

To estimate the effectiveness of IPTsc with DP in reducing community level malaria burden. We will test the hypothesis that malaria incidence will be lower in intervention clusters (randomised to receive IPTsc) than in control clusters (randomised to not receive IPTsc).
Uganda 2025-06-05 8:47:33 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Amina Hassan
ID: UNCST-2025-R017065
A STUDY OF CHILD MOTHERS’ EXPERIENCES ON COMMUNITY-BASED REHABILITATION IN MBALE DISTRICT, EASTERN UGANDA
REFNo: SS3834ES

Main objective/ purpose
The major objective of the study is to highlight the experiences of the child mothers' community-based rehabilitation services in Mbale District, Uganda.
Specific Objectives
1. To identify the challenges that the child mothers experience
2. To establish the support services they received from the community during pregnancy
3. To examine the support services they received from the community after delivery

Uganda 2025-06-05 8:44:56 2028-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aldomoro Burua
ID: UNCST-2024-R002082
Characterization and treatment outcomes of asymptomatic pulmonary tuberculosis from community screening in Uganda
REFNo: HS5744ES

1) To assess the factors associated with asymptomatic compared with symptomatic pulmonary tuberculosis
2) To determine the infectiousness of asymptomatic compared with clinical pulmonary tuberculosis.
3) To evaluate the treatment outcomes of subclinical compared to clinical pulmonary tuberculosis.

Uganda 2025-06-05 17:49:08 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary Namukisa
ID: UNCST-2025-R016850
PARTICIPANT COMPENSATION IN MEDICAL RESEARCH: PRACTICES AND PERSPECTIVES OF INVESTIGATORS AND RESEARCH ETHICS COMMITTEES IN UGANDA
REFNo: HS5901ES

1. To identify the factors influencing research compensation in medical research in Uganda.
2. To explore the perspectives of investigators and REC members regarding research compensation in medical research in Uganda.
3. To determine the common research compensation practices utilized in medical research conducted in Uganda.
Uganda 2025-06-05 17:17:52 2028-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Lorna Magara Florence
ID: UNCST-2025-R017918
An Inquiry into the Phenomenon of Innovation Hubs in Uganda
REFNo: SS3976ES

1) To examine stakeholder perceptions and definitions of innovation hubs – Understanding how the founder, innovators, and university faculty conceptualize the role and function of innovation hubs within Uganda’s socio-economic context. 2) To identify the challenges and support mechanisms influencing stakeholder engagement – The study will assess the barriers and constraints that innovators, university faculty, and the founder face in their interactions with MoTIV, as well as the available resources that support innovation and entrepreneurship. 3) To analyze how collaboration influences the innovation culture at MoTIV Innovation Hub – The research will explore how partnerships among industry, academia, and government impact knowledge exchange, creativity, and technological advancement within the innovation hub.
Uganda 2025-06-05 17:04:33 2028-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
Henry Ddungu
ID: UNCST-2019-R000966
Feasibility and acceptability of red blood cell exchange among patients with sickle cell disease in Uganda.
REFNo: HS5971ES

1.To determine the availability and accessibility of RBCX in Uganda

2.To assess the willingness of patients with SCD to undergo therapeutic apheresis.

3. To evaluate the perceived benefits and drawbacks of therapeutic apheresis among patients with SCD.

4. To explore the potential barriers to the implementation and uptake of therapeutic apheresis in Uganda.
Uganda 2025-06-02 17:42:17 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Steven  Puleh Sean
ID: UNCST-2021-R013722
R21 MALARIA VACCINATION AMONG COMMUNITIES IN NORTHERN UGANDA DISTRICTS: UPTAKE, ADHERENCE TO SCHEDULE, ASSOCIATED FACTORS AND VACCINE EFFECTIVENESS
REFNo: HS5968ES

General objective To assess the uptake and adherence to vaccine schedules, associated factors, and the effectiveness of the R21 malaria vaccine in reducing test positivity rates, disease severity, and hospitalization rates among targeted children in selected communities in Northern Uganda. Specific objectives: 1. To assess the knowledge, attitude, and perceptions among communities of northern Uganda (Study I) 2. To assess the level of uptake (at least 1 dose) of malaria vaccine in children in children targeted for vaccination and its associated factors among communities in northern Uganda (Study II) 3. To evaluate adherence to the first three (3) malaria vaccine schedules for control of malaria in children under five years and associated factors in communities of northern Uganda (Study III) 4. To evaluate the effectiveness of malaria vaccine on test positivity rate, severity of the cases, mortality rates in the control of malaria one year after the introduction of the vaccine among children under five years in northern Uganda (Study IV)
Uganda 2025-06-02 17:40:17 2028-06-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Annet Namusisi Mary
ID: UNCST-2025-R017592
Evaluation of the Uganda Public Health Bulletin impact
REFNo: HS5978ES

1. Determine the reach of the UPHB among national, district, and international stakeholders 2. Explore how readers perceive the relevance, quality, and usefulness of the UPHB 3. Assess Content Quality Using Standardized Scorecards 4. Analyze trends in digital engagement as measured by email open rates, click-through rates, and website traffic over the past five years 5. Evaluate the impact of the UPHB on public health decision-making within 9 years of existence
Uganda 2025-06-02 17:38:50 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WALAKIRA FELIX JOSHUA
ID: UNCST-2023-R007993
COMMUNITY PERCEPTIONS ON HERBAL MEDICINES USE IN TREATING UPPER RESPIRATORY INFECTIONS IN KATANGA SLUM, UGANDA; A WAY OF SPARING ANTIBIOTICS.
REFNo: HS5902ES

1. To explore prevailing perceptions and beliefs within the community regarding the efficacy of herbal medicines in treating upper respiratory infections.
2. To explore the perceived barriers and facilitators to the adoption of herbal medicines in treating Upper Respiratory Infections as a means of sparing antibiotics.
3. To determine the proportion of people in Katanga who have suffered from Upper Respiratory Infections.

Uganda 2025-06-02 17:37:03 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Holly Parsons Jane Emily
ID: UNCST-2024-R002678
Case Study: Exploring the Effectiveness of Village Health Teams in Uganda's 12 Refugee-Hosting District
REFNo: SS3874ES

The main objective on this research is to drive the narrative on a successful method of transition from humanitarian-funded to government ownership of health systems for refugees in low- and middle-income countries that depends on responsibility-sharing as part of the Global Compact on Refugees. The specific objective is to explore the effectiveness of Village Health Teams (VHTs) in Uganda's 12 refugee-hosting districts in preventing and treating human malaria by identifying key successes and key challenges of this health system, and then exploring how successes can be proliferated and how challenges can be mitigated.
Canada 2025-06-02 17:20:52 2028-06-02 Social Science and Humanities Non-Clinical Trial Degree Award
Amon Tayebwa
ID: UNCST-2024-R002098
THE ANATOMICAL VARIATIONS AND DISTRIBUTION OF THE HUMAN CORONARY ARTERIES: A CADAVERIC STUDY AT MBARARA REGIONAL REFERRAL HOSPITAL IN SOUTH WESTERN UGANDA.
REFNo: HS6003ES

1.What are the different branching and dominance patterns of the human coronary arteries amongst unclaimed bodies at Mbarara Regional Referral Hospital?
2.What are the different patterns of origin of coronary arteries at the sinotubular junction amongst unclaimed bodies at Mbarara Regional Referral Hospital?
Uganda 2025-06-02 17:17:36 2028-06-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Gloria Naome Aduku
ID: UNCST-2024-R015930
IMPACT OF ANTHROPOGENIC ACTIVITIES (TOURISM) AND PARASITISM ON PHYSIOLOGIAL STRESS IN GORILLAS (Gorilla beringei beringei) IN BWINDI IMPENETRABLE NATIONAL PARK
REFNo: NS971ES

• To evaluate six different Enzyme Immunoassays (EIA) for quantifying fGCMs in mountain gorillas.
• To investigate the effect of bacterial metabolism and environmental factors on the stability of faecal glucocorticoid metabolite (fGCM) concentrations post-defaecation
• To examine variation in parasitic burden and fGCM concentrations of spatially separated mountain gorilla groups.
• To examine parasitic burden and fGCM concentrations of mountain gorillas during high and low tourism activity.
• To identify specific parasitic infections that correlate with elevated fGCM concentrations in mountain gorillas.

Uganda 2025-06-02 17:16:50 2028-06-02 Natural Sciences Non-Clinical Trial Degree Award
AHEEBWA ROGGERS COLLINS
ID: UNCST-2025-R017036
Tax Policies And Financial Performance Of Small & Medium Enterprises (SMEs) in Uganda: A Case Of SMEs in Kabale District
REFNo: SS3844ES

i. To examine the effect of tax compliance costs on the financial performance of small and medium enterprises in Kabale district
ii. To examine the effect of tax incentives on the financial performance of small and medium enterprises in Kabale district.
iii. To examine the effect of tax rates on the financial performance of small scale and medium enterprises in Kabale district.


Uganda 2025-06-02 17:15:52 2028-06-02 Social Science and Humanities Non-Clinical Trial Degree Award
Kamya Moses
ID: UNCST-2020-R014203
A case-control study to assess the effectiveness and safety of the R21/matrix-M malaria vaccine
REFNo: HS6009ES

To assess the Vaccine Effectiveness (VE) of R21/Matrix-M vaccine against severe malaria caused by Plasmodium falciparum.

To assess the Vaccine Effectiveness (VE) of the R21/Matrix-M vaccine against clinical malaria in high-transmission perennial areas caused by Plasmodium falciparum.

To assess if the R21/Matrix-M vaccine recipients are at an increased risk of death (all-cause).
Uganda 2025-06-02 17:04:40 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
PROTOCOL FOR THE PERFORMANCE EVALUATION OF ALINITY M HIV-1 ASSAY USING DRIED BLOOD SPOT SPECIMENS HIV VIRAL LOAD ASSAY FOR WHO PREQUALIFICATION ASSESSMENT
REFNo: HS6061ES

• To assess the Alinity m HIV-1 DBS assay’s agreement with a cobas HIV-1 Quantitative nucleic acid test for use on the cobas 6800/8800 Systems (Roche Diagnostics GmbH) on clinical specimens, including:
o Quantitative assessment of bias, limits of agreement and correlation
o Misclassification above or below the clinical threshold (1000 copies/mL)
• To assess the analytical performance of the Alinity m HIV-1 assay using DBS:
o Precision (repeatability and within-laboratory reproducibility)
o Linear range on the main subtypes
o Limit of detection
o Cross-contamination
• To describe the operational characteristics and ease of use of the Alinity m HIV-1 assay using DBS and its suitability for use in countries with limited infrastructure.

Uganda 2025-05-29 17:20:17 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
STANDARDTM M10 HR-HPV: Evaluation of Clinical Performance and Usability in the hands of untrained users.
REFNo: HS6022ES

Demonstration of usability of the STANDARDTM M10 Hr-HPV assay. ,Demonstration of sample type equivalence for the STANDARDTM M10 Hr-HPV assay: ThinPrep® PreservCyt® Solution (Hologic) vs. BD SurePathTM Collection Vial (Becton, Dickinson and Company),Determination of the relative diagnostic sensitivity and specificity i.e. compared with the Roche Cobas HPV assay (used according to the current standard of care at the study site).,Determination of clinical accuracy i.e. absolute diagnostic sensitivity for CIN2+ and CIN3+ and absolute diagnostic specificity for ≤ CIN1.,To demonstrate the clinical performance of the STANDARDTM M10 Hr-HPV assay when used by healthcare professionals in a laboratory setting or health institution (i.e. intended use setting), the following objectives have been defined.,
Uganda 2025-05-29 17:19:03 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anatoli Mawanda
ID: UNCST-2024-R015927
GENETIC AND MOLECULAR DETERMINANTS OF BREAST CANCER DISPARITY AMONG AFRICAN, AFRICAN AMERICAN AND WHITE POPULATIONS
REFNo: HS6015ES

To study the genetic, molecular, and biological regulators of breast cancer in Ugandan
women and compare them with African American and white women.
Uganda 2025-05-29 17:17:31 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christabel Gero Anyango
ID: UNCST-2025-R017108
Perspectives of Child Domestic Workers and Their Employers: A Qualitative Study in Kampala, Uganda
REFNo: SS3860ES

• To establish patterns of entry into, exit out of and conditions of child domestic work in the Ugandan setting, including patterns that constitute human trafficking. Entry patterns will include decision making and influences to enter domestic work, while exit will encompass strategies used to transition to other work roles and the types of work roles entered following domestic work. • To understand employers’ perceptions of and views on child domestic workers, including reasons for recruiting younger workers, strategies to recruit CDWs, views on the benefits, drawbacks and development needs of younger workers, treatment and remuneration of CDWs, and awareness of laws and policies related to young workers, among others.
Kenya 2025-05-29 17:15:05 2028-05-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jeya Sushimitha Jawahar Kanth
ID: UNCST-2024-R016269
Evaluating the Impact of Social Media Influencers on Tobacco Use Among Urban Youth in Africa: A Comparative Mixed Methods Study Across Kampala, Nairobi, and Lagos
REFNo: SS3850ES

Main Objective
1. To explore and compare the role of social media influencers in shaping tobacco use behaviors among urban youth (ages 18-29) residing in Kampala, Nairobi, and Lagos by examining tobacco use prevalence, influencer messaging, and youth perspectives.
Specific Objectives
1. To determine the prevalence of tobacco use among urban youth (18-29 years) in Nairobi, Lagos, and Kampala.
2. To assess the relationship between exposure to influencer content and tobacco use behaviors among urban youth.
3. To analyze the content and reach of pro-tobacco messages shared by social media influencers among the target youth population.
4. To investigate urban youth perceptions of how influencers impact their decisions and attitudes toward tobacco use.
India 2025-05-29 17:14:22 2028-05-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Denis Nansera
ID: UNCST-2024-R004002
Improving HIV testing among Children under five in Rural Uganda
REFNo: HS5829ES

The main objective of this study is to develop a traditional healer facilitated paediatric HIV testing program to improve access to paediatric HIV testing. To do this, we will first use qualitative study methods to determine factors that influence HIV testing among paediatric clients of TH and guide adaptation of the TH-facilitated HIV testing program for children. We will then implement a pilot study to evaluate offering paediatric HIV testing at traditional healer locations in southwestern Uganda.
Uganda 2025-05-29 17:12:49 2028-05-29 Medical and Health Sciences Clinical Trial Non-degree Award
Nanyonga Elizabeth Monica
ID: UNCST-2025-R018232
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REFNo: SIR516ES

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Uganda 2025-05-27 9:30:38 2028-05-27 Engineering and Technology Clinical Trial Non-degree Award
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
“Exploring Acceptability: Expanding Family Planning Services in Pharmacies and drug shops in Uganda.”
REFNo: HS5733ES

a. To assess the acceptability of family planning including implant provision through pharmacies and drug shops among key stakeholders in Uganda.
b. To examine the role of non-monetary incentives (e.g., training, certification, recognition) in motivating pharmacy and drug shop operators to provide FP services.
c. To explore the willingness and capacity of pharmacy and drug shop providers to comply with government reporting requirements for FP service provision.
d. To identify perceived potential facilitators and challenges to the successful implementation of implant provision in pharmacies and drug shops in Uganda.

Uganda 2025-05-27 11:03:29 2028-05-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martina Ferracane Francesca
ID: UNCST-2025-R016796
Assessing the digital trade rules in Rwanda and Uganda
REFNo: SS3942ES

Main Objective 1. Address the knowledge gap between Uganda’s current legal framework and its potential enabling or restrictive impact on digital trade development, ensuring that policy initiatives and policy framework align with the needs of businesses engaging in digital trade. Specific Objectives 1. Identify the challenges faced by private sector entities, including SMEs and start-ups, in digital trade. 2. Provide actionable policy recommendations to improve Uganda’s digital trade framework. 3. Assess the existing digital trade policies in Uganda and identify areas for improvement.
Italy 2025-05-23 8:20:18 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Lwasa
ID: UNCST-2025-R018323
Value Chain Study and Market Assessment Farmer Managed Natural Regeneration (FMNR) Catalyst Project
REFNo: A607ES

The main objective of the value chain and market analysis was to identify complementary livelihood options or enterprises in FMNR project implementation areas that can be established in the demonstration and learning sites.
Uganda 2025-05-23 14:12:56 2028-05-23 Agricultural Sciences Non-Clinical Trial Non-degree Award
DARIUS OWACHI
ID: UNCST-2022-R009373
Impact of Antimicrobial Stewardship Interventions on Healthcare Workers’ Antibiotic Prescription Patterns and Compliance with Standard Treatment Guidelines at Kiruddu Hospital; A Quality Improvement Study.
REFNo: HS5989ES

To assess the impact of antimicrobial stewardship interventions on the knowledge levels, antibiotic prescription patterns and compliance to standard treatment guidelines, by healthcare workers at Kiruddu National Referral hospital through quality improvement methods. ,
Uganda 2025-05-23 14:10:37 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Violet  Gwokyalya
ID: UNCST-2022-R010490
Drivers of under-prescription of cervical cancer screening: evidence from Uganda
REFNo: HS5957ES

Main Objective
1. To quantify the drivers of under-prescription of cervical cancer screening among providers of routine care in Uganda
________________________________________
Specific Objectives
1. To evaluate whether providers lack knowledge of recommended cervical cancer screening practices
2. To identify patient characteristics that predict screening recommendation for cervical cancer.
3. To evaluate whether providers with appropriate knowledge of cervical cancer screening recommend screening to their clients (i.e., whether a know-do gap exists).

Uganda 2025-05-23 14:05:07 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
Analysing HIV-1 Reservoir Kinetics, and Host Immune Interactions among non-B subtypes.
REFNo: HS5936ES

General Objective

To understand the dynamics of HIV-1 reservoirs and host immune interactions among non-B subtypes infected participants in Uganda.

Specific objectives:
1. To compare the dimensions of the HIV-1 reservoir among Ugandans, including individuals with high viral loads at the start of ART, and those who have been on ART for varying durations.
2. To detect HIV-1 viral properties associated with latent reservoirs across HIV-subtypes, examining how these patterns may differ and contribute to disparities in reactivation tendencies in Uganda.
3. To detect immune correlates in relation to host characteristics, including HIV-1 specific, B-cells, innate immune cells, CD4 and CD8 cell lineage activation, and exhaustion markers.
4. To develop a supervised machine learning algorithm to predict the HIV-1 latent reservoir behaviours in Uganda.

Uganda 2025-05-23 14:00:42 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty Nalikka
ID: UNCST-2024-R016316
Ecological and epidemiological dynamics of viruses in Ugandan bat populations.
REFNo: NS969ES

1. To determine the prevalence, diversity and genetic variation of viruses in different bat species, considering both time and space.
2. To use host density, distribution, and pathogen prevalence to develop models that can be used to forecast spillover risks from bats to other animals, including humans.
3. To investigate the duration of immunity to viruses in bats by sampling individuals across different age groups over time.

Uganda 2025-05-23 13:58:46 2028-05-23 Natural Sciences Non-Clinical Trial Degree Award
Muge Cevik
ID: UNCST-2022-R011548
Improving surveillance and detection of MPXV in Uganda
REFNo: SS3940ES

• To determine seroprevalence of MPXV among people living with HIV in Uganda • To elucidate the risk factors associated with infection.
UK 2025-05-23 13:57:06 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
ochuga patrick olanya
ID: UNCST-2024-R015276
PREVALENCE, AND FACTORS ASSOCIATED WITH CHORIOAMNIONITIS AMONG WOMEN ADMITTED WITH PPROM AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5949ES

To determine the prevalence and factors associated with chorioamnionitis among women admitted with PROM at MRRH
Uganda 2025-05-23 13:54:31 2028-05-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Nina Rugambwa Olivia
ID: UNCST-2019-R000213
SAFEGUARDING MENTAL HEALTH OF CHILDREN WITH PHYSICAL DISABILITIES IN INCLUSIVE PUBLIC PRIMARY SCHOOLS: A CASE OF KAMULI DISTRICT, UGANDA
REFNo: SS3894ES

To explore the coping strategies of children with physical disabilities and their relationship to mental well-being in schools in Kamuli District.,3. To examine mental health safeguarding measures and their implementation in inclusive government primary schools in Kamuli District ,2. To document cultural beliefs and practices that promote mental health and inclusiveness of children with disability at school and in their communities in Kamuli District,1. To determine the mental health status of children with physical disabilities in government-inclusive primary schools in Kamuli district,This study seeks to create awareness about the mental health of children with disabilities and enhance their safety in inclusive government primary schools in Kamuli district.,
Uganda 2025-05-23 13:43:10 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Phiona Bukirwa
ID: UNCST-2022-R009880
Colorectal Cancer Biology: Clinicopathologic characteristics, Mismatch Repair (MMR) status and prognostic factors of colorectal carcinoma in Sub-Saharan Africa
REFNo: HS5980ES

1. To determine the prevalence of Mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
2. To assess the association between histopathological parameters like tumor grading, tumor type, frequency of tumor infiltrating lymphocytes and tumor budding in microsatellite instability-high (MSI-H) FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
3. To assess the association of clinical finding (age, sex, TNM stage, site of tumour) with mismatch repair status in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
4. To assess the prevalence of BRAF and KRAS mutation in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.

Uganda 2025-05-23 13:40:32 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Godfrey Kubiriza Kawooya
ID: UNCST-2024-R003138
Eco-innovative technologies for improved nutrition, sustainable production and marketing of Agro-ecological food products in Africa (INNOECOFOOD)
REFNo: A574ES

Main objective of the baseline study
The main objective of the baseline study is to scope community indigenous knowledge, gaps, attitudes and aquaculture practices in local lakes and rivers (living labs) on production, processing, marketing and consumption of aquaculture value chains (fish and selected Spirulina species) and insect species in Uganda.

Specific Objectives
i.To determine the current community Knowledge on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
ii.To determine the current community Attitude on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
iii.To determine the current community Practices on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
iv.Assess how socio-demographics factors influence the production, processing and consumption of fish, spirulina and insects as food and feed.

Uganda 2025-05-23 13:39:33 2028-05-23 Agricultural Sciences Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
Genetic Associations of INfertility in Africa (The GAIN Study)
REFNo: HS5967ES

The GAIN study aims to identify genetic variants associated with unexplained primary infertility in African women
Uganda 2025-05-23 13:37:00 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
Uganda Population-based HIV Impact Assessment (UPHIA 2024-2025)
REFNo: HS5817ES

The primary objectives of UPHIA 2024-2025 are to:
1) Estimate the national and regional prevalence of HIV viral load suppression (VLS – defined as HIV RNA <1000 copies/milliliter(mL) in adults ages 15 years or older in the general population.
2) Estimate the prevalence of HIV at the national and regional level
3) Assess progress towards the UNAIDS 95- 95- 95 targets at the national and regional level

The secondary objectives of the survey are to:
1) Estimate the HIV incidence at the national level
2) Estimate the prevalence of HIV-related risk behaviors, knowledge, and attitudes
3) Establish the behavioural and demographic determinants of HIV prevalence and incidence
4) Determine the exposure to, uptake of and barriers to access to HIV-related services
5) Estimate the prevalence of elevated blood pressure, elevated blood glucose and obesity among the general population and people living with HIV
6) Assess the facilitators of and barriers to viral load suppression among people living with HIV on ART in two regions with the lowest VLS, based on the UPHIA 2020-21 survey findings.

Uganda 2025-05-23 13:34:26 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID KITYA
ID: UNCST-2022-R009620
Analysis of the out-of-pocket costs of neurosurgical care in Uganda
REFNo: HS5875ES

3. To assess the socioeconomic impact of neurosurgical care on patients and their families/caregivers in Uganda, and to identify the key cost-related factors contributing to this burden within the local context.,2. To ascertain the proportion of patients experiencing catastrophic and impoverishing healthcare expenditure due to their neurosurgical care.,1. To determine the direct and indirect out-of-pocket costs borne by patients receiving neurosurgical care.,The main objective of this study is to quantify the OOP expenditure costs for patients receiving neurosurgical care in Uganda to estimate the proportion of patients experiencing CHE,
Uganda 2025-05-23 13:30:41 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MARTHA GIMONO
ID: UNCST-2024-R016208
The Readiness of Emerging Adults (18-25 years) Living with Type 1 Diabetes to Transition from Pediatric to Adult Healthcare in Jinja District - Uganda.
REFNo: HS5871ES

1. To develop transition screening tools for emerging adults living with T1D in Jinja District, Uganda.
2. To understand facilitators of transition readiness among emerging adults living with T1D in Jinja District, Uganda.
3. To determine the level of transition readiness among emerging adults living with T1D in Jinja District, Uganda

Uganda 2025-05-23 13:28:29 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Oculi Jasper
ID: UNCST-2024-R004987
Azotobacter and Pseudomonas bio-fertilizer for enhanced yield of maize (Zea mays) and Turtle beans (Phaseolus Voulgaris) in Uganda
REFNo: A594ES

i. To isolate and characterize isolates of azotobacter and pseudomonas bio-fertilizers which is efficacious as bio-fertilizer in Uganda.
ii. To evaluate the efficacy of azotobacter and pseudomonas bio-fertilizers on growth and yield of maize (Zea mays) and turtle beans (phaseolus voulgaris) in the greenhouse trial at Kyambogo University.
iii. To evaluate the efficacy of azotobacter and pseudomonas bio-fertilizers on growth and yield of maize (Zea mays) and turtle beans (phaseolus voulgaris) in the field at Kyambogo University farm.

Uganda 2025-05-23 13:24:17 2028-05-23 Agricultural Sciences Non-Clinical Trial Degree Award
Johnblack Kabukye Kabaalu
ID: UNCST-2019-R001109
PEPROOM – Patient Engagement and Patient-Reported Outcomes in Oncology using Mobile health tools in Uganda: A mixed-methods formative study
REFNo: SS3900ES

Main Objective
1. This project aims to enhance patient engagement and empowerment by increasing cancer awareness through efficient and effective dissemination of cancer information and advice. It also aims to develop/adapt patient-reported outcomes (PROs) measures for patients with cancer in Uganda, and improve PROs through cancer awareness, PRO tracking, reminders and personalized support. Overall, the project will contribute to research and evidence on patient-centered care in Uganda.
Specific Objectives
1. to explore knowledge, attitudes, and practices of cancer care providers and patients at the Uganda Cancer Institute (UCI) with regards to patient empowerment and patient-reported outcomes (PROs
2. to identify PROs considered most important, relevant, and/or actionable for cancer care at the UCI, and develop/adapt measures (tools) to track these PROs
3. to develop, implement, and evaluate a telephone system for automated provision of cancer information related to the PROs and for administration of the PRO measures in (ii) above (i.e., in audio telephone questionnaire format)
4. to study the impact of the telephone system on the PROs above and other selected clinical care processes and outcomes (e.g., satisfaction with care, adherence to appointments, disease progression)
Uganda 2025-05-23 13:23:23 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richard Idro
ID: UNCST-2021-R013599
Development of a clinical decision support (CDS) tool to address the epilepsy treatment gap in Uganda: A pilot study
REFNo: HS5127ES

Aim 1: To develop a machine learning-enabled clinical decision support (CDS) tool to choose an appropriate anti-epileptic drug for initiating treatment among children with epilepsy. Aim 2: To evaluate the effect of the CDS tools on the treatment gap among children with epilepsy in nine health clinics around KCCA and Wakiso, where CDS tool will be implemented. Aim 3: To determine the adoptation and acceptability of the CDS tool among non-specialist providers, who diagnose and treat children with epilepsy (psychiatry clinical health officers and psychiatry nurse) in clinics around KCCA.
Uganda 2025-05-22 12:07:57 2028-05-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Asiimwe Aisha
ID: UNCST-2024-R015631
CORPORATE CULTURE AND EMPLOYEE PERFORMANCE IN SELECTED LOCAL GOVERNMENTS IN WESTERN UGANDA
REFNo: SS3703ES

To find out the moderating effect of government policies on employee performance in the Kasese and Kabarole local governments in Western Uganda,To establish the extent to which change management influences employee performance in Kasese and Kabarole Districts local governments in Western Uganda,To assess the extent to which employee engagement influence employee performance in Kasese and Kabarole Districts local governments in Western Uganda,To determine the extent to which performance management mechanisms influence employee performance in Kasese and Kabarole Districts local governments in Western Uganda,To examine the extent to which communication patterns influence employee performance in Kasese and Kabarole Districts local government in Western Uganda.,The purpose of this study will be to evaluate the relationship between corporate culture and employee performance in Kasese and Kabarole Districts local governments in Western Uganda. ,
Uganda 2025-05-16 9:59:38 2028-05-16 Social Science and Humanities Non-Clinical Trial Degree Award
Harriet  Kizza
ID: UNCST-2024-R003661
EXPLORING FORMATIVE ASSESSMENT PRACTICES IN PRE-SERVICE TEACHER EDUCATION UGANDAN UNIVERSITIES
REFNo: SS3806ES

1.To analyze the formative assessment practices currently employed in pre-service teacher education within Ugandan universities
2.To explore the experiences of teacher educators regarding the implementation of formative assessment in pre-service teacher education
3.To investigate students experiences and perceptions of formative assessment in pre-service teacher education within Ugandan universities
4.To recommend best practices for formative assessment that can enhance teaching and learning in pre-service teacher education programs

Uganda 2025-05-16 9:58:05 2028-05-16 Social Science and Humanities Non-Clinical Trial Degree Award
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"A prosperous Science and Technology Led Ugandan Society."