Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Anthony  Batte
ID: UNCST-2022-R011127
Appraising the Critical Role of prognostic Biomakers in the Assesment and Triage of sick African newborns advancing a point-of-care device (ACROBAT)
REFNo: HS8441ES

To determine the analytical performance of rttPoC to measure baseline proposed biomarker levels compared to gold-standard laboratory techniques.,To determine the prognostic performance of rttPoC performed at baseline in predicting other adverse outcomes (i.e. invasive bacterial disease, length of hospitalisation in regular wards, in the Neonatal Intensive Care Unit and/or other applicable wards, unscheduled visit to healthcare, readmission, discharge with a severe diagnosis or sequelae) up to 48 hours, 7 days, 28 days, and 90 days in sick neonates at neonatal, maternity, and emergency wards. ,To determine the prognostic performance of rttPoC performed at baseline to predict escalation of care or death up to 48 hours, 7 days, and 90 days in sick neonates at neonatal, maternity, and emergency wards. ,To determine the prognostic performance of rttPoC performed at baseline to predict escalation of care or death up to 28 days in all-cause sick neonates presenting at neonatal, maternity, and emergency wards in hospitals of four Sub-Saharan African countries.,To evaluate the performance of rttPoC, a rapid prognostic test based on the quantification of a proposed biomarker (sTREM-1, suPAR or other) levels, to risk stratify all-cause sick neonates across neonatal, maternity, and emergency wards in hospitals of four Sub-Saharan African countries.,
Uganda 2026-09-17 14:04:27 2029-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nina Rugambwa Olivia
ID: UNCST-2019-R000213
Leveraging Indigenous Knowledge Strategies to reduce risky sexual behavior among out- of- school rural Teenage Girls: A Case of Bugiri District, Uganda
REFNo: SS5249ES

1. To identify and document existing indigenous knowledge (IK) on sex education and reproductive health information for out-of-school teenage girls in Bugiri District.
2. To explore the information needs of out-of-school teenage girls regarding sex education and indigenous reproductive health information in Bugiri District.
3. To describe the information sources and community support systems that out-of-school teenage girls rely on for sex education and indigenous reproductive health information.
4. To develop a framework to facilitate access to and use of reliable indigenous information on sex education and reproductive health for out–of–school teenage girls in Bugiri District.

Uganda 2026-09-17 14:01:52 2029-09-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
REConneCteD: Risk-Enhanced Community Care After Discharge
REFNo: HS8114ES

3. Use implementation science theories/frameworks to facilitate and characterize the processes by which CHWs and implementing sites adopt and integrate REConneCteD into their routine work.,2. Conduct a comprehensive return on investment (ROI) analysis to demonstrate the ROI for every dollar invested in REConneCteD. ,1. Evaluate the effectiveness of REConneCteD through a stepped wedge clinical trial of incomplete design ,To implement and evaluate a digital integration of facility-based Smart Discharges program with a community-based digital platform (electronic Community Health Information system, eCHIS) and assess its impact on post discharge mortality and key essential care processes among children with acute infectious illness.,
Uganda 2026-09-17 13:58:19 2029-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Flavia Luwedde Aliba
ID: UNCST-2023-R007953
Characterisation of Early onset colorectal cancer by anatomical site and black carbon distribution among indigenous Africans at the Uganda Cancer Institute
REFNo: HS8231ES

General Objective The aim of this study is to determine the association between the anatomical site of EOCRC, its characteristics and distribution of black carbon among indigenous Africans at the Uganda Cancer Institute. Specific objectives 1. Describe sociodemographic, clinical, histopathological and molecular characteristics of EOCRC 2. Describe the distribution of black carbon in EOCRC tissues and body fluids 3. Determine the association between characteristics of EOCRC and black carbon distribution 4. Determine the association between characteristics of EOCRC and its anatomical site
Uganda 2026-09-17 13:49:07 2029-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Henry Akra Ayias
ID: UNCST-2026-R023985
Recommendations for Learning Management Systems Usage and e-learning Quality in Ugandan Higher Education Institutions
REFNo: SS5815ES

The theoretical secondary objectives are: – to establish the effect of behavioural intention on the usage behaviour of the LMS at the institute – to establish the effect of performance expectancy on behavioural intention to use the LMS at the institute as moderated by gender and age – to establish the effect of effort expectancy on behavioural intention to use the LMS at the institute as moderated by gender, age and experience – to establish the effect of the social influence on behavioural intention to use the LMS at the institute as moderated by gender, age and experience – to establish the effect of the facilitating conditions on use behaviour as moderated by age and experience The empirical primary objectives are: – to establish the effect of the performance expectancy, effort expectancy, social influence and facilitating conditions on the quality of e-learning at the institute. – to establish other factors that affect the behaviour intention and use behaviour of the LMS at the institute
Uganda 2026-09-17 13:47:14 2029-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
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