Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Robert Mboizi Baldwin
ID: UNCST-2020-R014356
Field performance of the Global Alignment of Immunization Safety Assessment in Pregnancy (GAIA) Maternal and Neonatal Outcome Case Definitions for the Evaluation of Adverse Events in pregnancy in clinical trials in low resource settings.
REFNo: HS7349ES

1. To assess the applicability of the GAIA case definitions for adverse events in maternal immunisation trials conducted in Uganda. 2. Determine the highest level of diagnostic level of certainty for each GAIA case definition. 3. To assess the limitations of the GAIA case definitions for adverse events in maternal immunisation trials conducted in Uganda.
Uganda 2026-04-10 19:13:33 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peterson Kikomeko Kato
ID: UNCST-2019-R000881
Reassessing Mid-Upper Arm Circumference as a Predictor of Nutritional Status and Pregnancy Outcomes among Pregnant Adolescents in Bundibugyo District, Uganda
REFNo: HS7233ES

i. To determine maternal hemoglobin status during pregnancy, MUAC across gestation, and gestational weight gain among pregnant adolescents and adult women attending ANC in Bundibugyo District, Uganda. ii. To determine the rate of increase in MUAC and compare MUAC trajectories between pregnant adolescents and adult women across gestational stages among those attending ANC in Bundibugyo District, Uganda. iii. To examine dietary intake patterns and their association with MUAC, gestational weight gain, and maternal hemoglobin status among pregnant adolescents and adult women attending ANC in Bundibugyo District, Uganda. iv. To determine optimal MUAC cut-off points for identifying undernutrition risk among pregnant adolescents attending ANC in Bundibugyo District, Uganda at different gestational stages. v. To evaluate associations of MUAC levels, rate of MUAC increase, gestational weight gain, and maternal hemoglobin status with key pregnancy outcomes (birthweight, preterm birth, small-for-gestational-age status, and maternal complications) among pregnant adolescents and adult women attending ANC in Bundibugyo District, Uganda. vi. To explore health workers’ and stakeholders’ perceptions, practices, and challenges regarding the use of MUAC for assessing maternal nutrition among pregnant adolescents and adult women, to contextualize and triangulate the quantitative findings.
Uganda 2026-04-10 19:12:34 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Lamunu Shereni
ID: UNCST-2025-R022324
Assessment and development of infectious diseases institute environment, social, and governance strategy, policy, and net zero roadmap
REFNo: SS5056ES

To assess and develop a comprehensive sustainability framework for the Infectious Diseases Institute (IDI) that strengthens institutional resilience, compliance, and accountability in alignment with local and international standards.1. To identify sustainability risks, gaps, opportunities, and strengths relative to Ugandan legal requirements, funder expectations, and international standards (e.g., GRI, IFRS, SDGs). 2. To map and engage key internal and external stakeholders to understand sustainability priorities, perceptions, and expectations of IDI’s sustainability performance. 3. To evaluate IDI’s environmental impact, including greenhouse gas (GHG) emissions, waste management, and resource utilisation. 4. To develop an institutional sustainability strategy, policy, and implementation roadmap. 5. To develop a Net Zero plan and monitoring and evaluation (M&E) matrix. 6. To develop an Environmental Aspects and Impacts Register to guide ongoing environmental management and compliance.
Uganda 2026-04-10 19:10:56 2029-04-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ponsiano Ocama
ID: UNCST-2019-R000440
Hepatitis B and HIV Cure Consortium (BICC): A Multi-Country Prospective Observational Cohort of People with HIV and Hepatitis B (PWHHB) and People with HBV (PWHB)
REFNo: HS7337ES

The primary objective of this protocol is to establish a multi-country prospective observational cohort of people with HIV and Hepatitis B virus (PWHHB) and people with HBV (PWHB) to establish a repository of data and specimens to accelerate HBV cure research.
Uganda 2026-04-10 19:09:27 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Deogratius Ssemwanga
ID: UNCST-2025-R021563
Pathogen Genomics in Community and Aircraft Wastewater for Outbreak Preparedness and Response in Uganda
REFNo: HS7430ES


The main objective is to establish an integrated wastewater-based surveillance system using NGS and AI-based machine learning (ML) models to detect, monitor and predict the spread of pathogens of public health importance and AMR in Uganda.
To characterize the diversity and temporal patterns of pathogens present
in wastewater collected from community, abattoir and aircraft sources
over a 12-month period.
ii. To detect and profile AMR genes in wastewater samples.
iii. To develop and validate AI-based analytical pipelines for processing,
interpretation, and forecasting infectious disease trends in Uganda over
the study period.
iv. To track seasonal trends in circulating pathogens and AMR genes by
integrating genomic data with epidemiological and clinical data
v. To develop and validate an optimized long-read mNGS pipeline using the
Oxford Nanopore MinION platform for detection and characterization of
pathogens and associated AMR in wastewater samples collected from
community and aircraft sources in Uganda.
Uganda 2026-04-10 19:07:13 2029-04-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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