Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Mark Jordans
ID: UNCST-2020-R014861
MENTAL HEALTH SYSTEMS AND A MENTAL HEALTH CARE PACKAGE FOR CHILDREN IN SELECTED REFUGEE SETTLEMENTS IN UGANDA (PAMOJA TUNAWEZA): PARTICIPATORY SYSTEM DYNAMICS AND CLIENT JOURNEYS
REFNo: SS4795ES

Objectives: 
This study aims to identify and evaluate key factors affecting the implementation and performance of a mental health care system in real-world settings.
Specific Research objectives and research questions:
1. To assess how well the mental health care system integrates and is compatible with existing mental healthcare services, infrastructure, and practices, both formal and informal with a particular focus on adolescent mental health.  
Research Question 1: Exploring how the mental health care system integrates, or is compatible, with existing mental health systems for adolescent mental health

2. To examine client experiences within the care system and identify opportunities to optimize service delivery and outcome.
Research Question 2: Evaluating the client experience, how this can be optimized within the care system

Netherlands 2026-02-18 12:19:41 2029-02-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bernard Mwesigye
ID: UNCST-2024-R016003
Delayed Door-to-Doctor time and associated factors among high acuity patients at the Accidents and Emmergency Unit of Mbarara Regional Referral Hospital
REFNo: HS6376ES

General:To assess the proportion of patients with delayed Door-to-Doctor time and associated factors among high acuity patients at the Accidents and Emergency Unit at Mbarara Regional Referral Hospital.
Specific objectives:
•To determine the proportion of high acuity patients with delayed Door-to-Doctor time at the Accidents and Emergency Unit of Mbarara Regional Referral Hospital.
●To determine the factors associated with delayed Door-to-Doctor time of high acuity patients at the Accidents and Emergency Unit of Mbarara Regional Referral Hospital.

Uganda 2026-02-18 12:16:08 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
LONG TERM CARDIAC AND PULMONARY CONSEQUENCES OF TB (LONG TB)
REFNo: HS6945ES

Establish a sample repository for future: a) host and M.tb whole genome sequencing for genome wide association studies, b) non-targeted multi-omic (transcriptome, proteome, metabolome) analysis and, c) targeted inflammatory/immunological pathway analysis,Characterize the prevalence, clinical presentation, and progression of sub-clinical CVD – a surrogate measure for subsequent PTCVD risk – among successfully treated adult drug-sensitive pulmonary TB cases,Characterize the prevalence, clinical presentation, and progression of PTLD among successfully treated adult drug-sensitive pulmonary TB cases,The overarching goal of this proposal is to establish a well characterized cohort of pulmonary TB patients with prospective cardio-pulmonary assessments and sample repository during and after treatment for comprehensive clinical phenotyping and immunological endotyping of post-TB sequelae,
Uganda 2026-02-18 12:14:31 2029-02-18 Medical and Health Sciences Non-degree Award
Natalia Marina Maure Marina
ID: UNCST-2024-R003148
Burden of cardiovascular disease risk factors among patients with tuberculosis in the karamoja sub-region of uganda. A cross-sectional survey
REFNo: HS6547ES

Primary objective: •Estimate the burden of CVD risk factors among TB patients at Matany and Moroto hospitals Secondary objectives: •Compare the burden of CVD risk factors between TB patients at Matany and Moroto hospitals and the burden of CVD risk factors in the Ugandan general population •Contrast the burden of CVD risk factors among TB inpatients and outpatients •Secondary Endpoint 2: Prevalence of CVD risk factors in TB inpatients and outpatients •Determine the 10-year cardiovascular event risk using the WHO/ISH risk prediction charts •Describe the associations between TB disease characteristics (pulmonary vs. extrapulmonary, drug-resistant vs. drug-susceptible, HIV co-infection status) and cardiovascular risk profiles
Italy 2026-02-18 12:13:03 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Abias Asiimwe Katesigwa
ID: UNCST-2025-R022247
Quality Improvement Strategies in Private Healthcare Facilities in Uganda
REFNo: HS7033ES

General Objective:
The primary purpose of this study is to investigate how Quality Improvement (QI) strategies become institutionalised within Uganda's private health facilities, examining the processes, factors, and outcomes that enable QI practices to transition from externally-driven initiatives to internally-sustained organisational norms.
Specific Objectives:
1. To identify and evaluate Quality Improvement (QI) strategies employed by private health facilities to enhance care quality.
2. To analyse the processes and critical factors influencing the institutionalisation of QI initiatives as a cultural norm within private health facilities, including challenges and strategies for their mitigation.
3. To assess the return on investment (ROI) of QI initiatives, focusing on their impact on care quality and operational efficiency in private health facilities.
4. To explore patients' perceptions and experiences regarding the quality of health services delivered by private health facilities.
5. To develop strategic recommendations for the institutionalisation of Quality Improvement (QI) initiatives within healthcare systems and to enhance care quality in the private health sector, informed by expert review and validation.

Uganda 2026-02-18 12:12:04 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Leah Mbabazi
ID: UNCST-2019-R000099
Factors associated with malaria vaccine uptake among caregivers of children under five years in North-Western Uganda
REFNo: HS6997ES

Primary objective: To assess the factors associated with malaria vaccine
uptake among caregivers of children under five years in North Western
Uganda.
Secondary objectives:
1. To determine the Malaria vaccine uptake level among
caregivers of children under five years in North-Western
Uganda.
2. To determine factors influencing malaria vaccine uptake
among caregivers of children under five years in North
Western Uganda.
3. To assess the attitudes and perceptions of the caregivers
towards the malaria vaccine in North-Western Uganda.
4. To assess care giver and health care provider experiences and
practices that influence malaria vaccination in North-Western
Uganda.
Uganda 2026-02-18 12:09:39 2029-02-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Moses Galiwango
ID: UNCST-2024-R015239
Impact of pregnancy on HIV reservoir activity, and associated immune dynamics, inducibility, and clonality
REFNo: HS7025ES

Test the impact of pregnancy on immune dynamics and HIV reservoir activity, inducibility, and clonality.
Uganda 2026-02-12 13:43:01 2029-02-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MARTHA GIMONO
ID: UNCST-2024-R016208
Improving Glycemic Control, Knowledge and Self-Management Practices Through Educational Curriculum for Young Adults with Type 1 diabetes in low-resource settings
REFNo: HS6947ES

1. To assess the changes in participants' diabetes knowledge, glycemic control, and self-management practices before and after participation in the Warrior Educator Training Program. 2. To evaluate the effectiveness of trained peer- educators in supporting Type 1 Diabetes (T1D) clinic operations and patient outcomes. 3. To assess the feasibility and impact of implementing the Warrior Educator Training Program in low resource settings.
Uganda 2026-02-12 13:41:51 2029-02-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victoria Rutter N/A
ID: UNCST-2025-R019210
Alignment of Fleming Fund’s Organisational Structure and Strategic Approach to Sustainable, Country-Led AMR Programme Delivery
REFNo: HS6774ES

Aim: To assess whether Fleming Fund’s current organisational structure and strategies effectively support sustainable, country-led AMR interventions. Specific objectives: 1. Evaluate how FF’s organisational structure aligns with its increasing focus on supporting sustainable, country-led AMR initiatives. 2. Examine the alignment of the Fleming Fund’s approach to national health priorities. 3. Assess factors affecting the sustainability of Fleming Fund-funded AMR programmes
UK 2026-02-12 13:40:57 2029-02-12 Medical and Health Sciences Non-Clinical Trial Degree Award
SHAFIGA BABIRYE
ID: UNCST-2024-R004302
Prevalence and factors associated with traditional medicine use among patients scheduled for surgery at Kyabirwa surgical center, Budondo sub-county-Jinja city
REFNo: HS7012ES

1. To determine the prevalence of traditional medicine use among patients scheduled for surgery at Kyabirwa Surgical Center, Budondo sub-county, Jinja city 2. To assess the factors associated with traditional medicine use among patients scheduled for surgery at Kyabirwa Surgical Center, Budondo sub county, Jinja city
Uganda 2026-02-12 13:40:07 2029-02-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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