Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,731
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
SONNY ASIMO
ID:
RISK FACTORS FOR FLUOROQUINOLONE RESISTANCE AMONG PATIENTS WITH SECOND LINE-DRUG RESISTANT TUBERCULOSIS EVALUATED AT THE UGANDA NATIONAL TUBERCULOSIS LABORATORY RefNo: CLARKE-2022-546
REFNo: HS2709ES

iii. To determine clinical factors associated with fluoroquinolone resistance in patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,ii. To characterize fluoroquinolone-resistance among patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,i. To determine the individual characteristics associated with fluoroquinolone resistance among patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,The study will determine the risk factors for fluoroquinolone resistance among patients with second-line drug resistant tuberculosis among previously evaluated samples in Uganda. ,
Uganda 2023-03-07 10:25:46 2026-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Perpetra Akite
ID: UNCST-2023-R008264
Systematic study of insect fauna in selected sites in Uganda (Insect Systematic Project)
REFNo: NS494ES

To sample a broad geographic area, including some of the never-collected or poorly-collected sites to yield new species that will be valuable to the insect systematic community and inform their conservation management
Uganda 2023-03-07 10:24:40 2026-03-07 Natural Sciences Non-Clinical Trial Non-degree Award
JOAN TUSABE
ID: UNCST-2021-R013942
FACTORS INFLUENCING UPTAKE AND ADHERENCE TO PREVENTION OF MOTHER TO CHILD TRANSMISSION (PMTCT) CARE AMONG REFUGEE HIV POSITIVE PREGNANT MOTHERS AGED 18 YEAS AND ABOVE IN KYANGWALI REFUGEE CAMP
REFNo: HS2711ES

1. To determine the level of uptake and adherence to prevention of mother to child transmission (PMTCT) services among refugee pregnant mothers aged 18 years and above in Kyangwali refugee camp

2. To determine factors associated with uptake and adherence to prevention of mother to child transmission (PMTCT) services among refugee pregnant mothers aged 18 years and above in Kyangwali refugee camp

3. To explore barriers and facilitators for uptake and adherence to prevention of mother to child transmission (PMTCT) services among HIV positive pregnant mothers aged 18 years and above in Kyangwali refugee camp


4. To determine strategies that can be put in place to improve uptake and adherence to prevention of mother to child transmission (PMTCT) among refugee HIV positive pregnant mothers in Kyangwali refugee camp?

Uganda 2023-03-07 10:23:51 2026-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Samson Udho
ID: UNCST-2021-R013728
Respectful maternity care in childbirth among adolescents aged 14 to 19 years in rural northern Uganda: a mixed-method study
REFNo: HS2727ES

The objectives are to: 1. Determine the prevalence of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 2. Determine the predictors of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 3. Explore the experiences of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 4. Explore the drivers of D&A of adolescents aged by SBA during childbirth in public health facilities in rural northern Uganda.
Uganda 2023-03-02 16:34:50 2026-03-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Fred Kaggwa
ID: UNCST-2022-R008842
Evaluating Mbarara University of Science and Technology (MUST) Internal Quality Assurance Mechanisms (IQAMs) on her Quality
REFNo: SS1629ES

General Objective
To evaluate MUST’s IQAMs on her quality using the IUCEA Model
Specific Objectives
1.To evaluate MUST’s IQAMs on the quality of Teaching and Learning
2.To examine MUST’s IQAMs on the quality of Research and Innovations
3.To assess MUST’s IQAMs on the quality of Community outreach

Uganda 2023-03-02 16:23:10 2026-03-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
ESTABLISHMENT AND EVALUATION OF CAPRI CELLS IN UGANDA FOR ADOPTIVE CELL THERAPY
REFNo: HS2684ES

1. Evaluate the reproducibility of Cascade Primed Cells with Apheretic collected Autologous PBMCs in Uganda
2. Test the effect of the reproduced CAPRI cells on Lung and Cervical cancer cells in vitro

Uganda 2023-03-02 15:39:34 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rachel Brathwaite
ID:
Assessing the Feasibility of Economic Approaches to Prevention of Substance Abuse among Adolescents
REFNo: HS2683ES

Aim 1. Examine the prevalence and consequences of ADU in a cohort of 200 AYLHIV (ages 18-24) seen at six (6) HIV clinics in southwestern Uganda.
Aim 2. Using a mixed methods approach, identify the multi-level (individual, interpersonal, community and structural) factors associated with ADU among AYLHIV.
Aim 3. Using a subset of the sample, explore the feasibility and short-term effects of a family-based economic empowerment intervention on ADU among AYLHIV.

Trinidad and Tobago 2023-03-02 15:32:31 2026-03-02 Medical and Health Sciences Clinical Trial Non-degree Award
NALWANGA ROSEMARY
ID:
Towards reconstructing latitudinal and altitudinal temperature gradients from the Last Glacial Maximum to the Present – Development of a globally applicable palaeothermometry method based on luminescence
REFNo: NS487ES

Reconstruction of surface air temperatures over the past 20,000-30,000 years along an
Achieve a better understanding of atmospheric dynamics in the tropics during the transition
from the Pleistocene to the Holocene
altitudinal gradient (lapse rate) and comparison to currently measured temperatures
Uganda 2023-03-02 15:14:46 2026-03-02 Natural Sciences Non-Clinical Trial Non-degree Award
Victoria Nambasa Prudence
ID: UNCST-2022-R008757
Landscape Assessment To Understand Maternal Vaccine Pharmacovigilance In Uganda
REFNo: HS2680ES

Main objective
The aim is to conduct a rapid assessment gap analysis and stakeholder mapping for safety monitoring of vaccines used in pregnancy and potential for use of Electronic Medical Record (EMR) for sentinel site surveillance in Uganda for post licensure studies as well as current tetanus and COVID-19 vaccination. The results of the assessment will inform areas of focus for establishment of robust safety surveillance of novel maternal vaccination and vaccines that maybe administered during pregnancy in pandemic situations in the country.
Specific objectives
1. Map stakeholders involved in regulation, policy setting, collection and reporting of adverse events following maternal vaccination and their linkages
2. Understand the existing methods, tools, and information flow for collecting and flow of adverse event following maternal vaccination
3. Mapping of current Electronic Health Record and registries roll-out and how they interface with national drug safety reporting system especially in relation to maternal vaccination
4. To understand the Community views, and perceptions on vaccination and reporting of AE during maternal immunization

Uganda 2023-03-02 15:08:39 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edmund  Mugayehwenkyi Kenneth
ID:
Women Rise Together across the Lifecourse (Write-Life)
REFNo: SS1633ES

3. What do women need to address their health and wellbeing issues and to feel more empowered? ,2. How empowered are women feeling? Document levels of perceived empowerment among women across the lifecourse, from young women through middle aged, to older women as well and capture the varied experiences of women in varied socioeconomic, cultural and community situations.,1. How are women doing? Examine associations between work (both paid and unpaid) and health throughout the COVID-19 pandemic among women across the lifecourse.,
Uganda 2023-03-02 14:46:12 2026-03-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Irumba Eleazar Paddy
ID:
The environmental stewardship by the church of Uganda in Albertine region- a case of Bunyoro-Kitara diocese.
REFNo: HS2675ES

4. To Explore the Theological Practices that the Church can use to enhance Environmental Stewardship in the Albertine Region.,3. To Establish the Relationship of Religious Teachings and Ethical Practices regarding Environmental Stewardship in the Albertine Region.,2. To Examine the role played by Church of Uganda in Environmental Stewardship in the Albertine Region,1. To investigate the current factors responsible for Environmental Degradation in the Albertine Region,
Uganda 2023-03-02 14:04:06 2026-03-02 Medical and Health Sciences Non-Clinical Trial Degree Award
John Bosco Ddamulira Mayanja
ID: UNCST-2022-R010819
ASSESSMENT OF THE MAGNITUDE AND CORRELATES OF HIV STIGMA AND DISCRIMINATION AND ITS EFFECTS ON THE COUNTRY’S HIV RESPONSE
REFNo: HS2690ES

To describe how different groups are affected by HIV related stigma and discrimination especially the key populations. ,To identify factors that perpetuate or mitigate stigma as well as the actions (resilience) taken by PLHIV to mitigate the impact of stigma and discrimination,To assess the effect of stigma and discrimination on the country’s HIV response.,To describe trends in experience of stigma and discrimination among PLHIV over time (comparing 2013, 2019 and 2022).,To determine the prevalence and distribution of the modes (internal and external) of HIV related stigma and discrimination manifestations among PLHIV ,To assess the magnitude and correlates of HIV stigma and discrimination and its effects on the country’s HIV response ,
Uganda 2023-03-02 14:02:36 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Harriet Mpairwe
ID: UNCST-2025-R017439
Causes And MEchanisms foR non-atopic Asthma in children (CAMERA) Study
REFNo: HS2510ES

There is an urgent need for new and innovative research into the causes of non-atopic asthma (NAA), and the likely mechanisms involved. The objectives of this study are therefore to: I. investigate the causes of NAA in a variety of settings: high and low asthma prevalence, HICs and LMICs (Work Package 1 (WP1) II. investigate three possible mechanisms of NAA in these different settings, including the relative importance of neural mechanisms (Work Package 2 (WP2)) This intended scientific value of study is to provide key ground-breaking insights into the causes and mechanisms of the poorly-studied yet predominant non-atopic asthma phenotype because: (i) non-atopic asthma likely has different causes from atopic asthma, and these have been little studied to date in both high-income countries and low- and middle-income countries; (ii) non-atopic asthma likely involves different mechanisms, which require different treatments. This study is likely to show, in a variety of settings, that a substantial proportion of non-atopic asthma may involve different mechanisms, and will identify new directions and priorities for prevention, mechanistic research, and the development of new therapies
Uganda 2023-03-02 13:54:33 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Iddi  Matovu
ID:
HIV RISKS AND INFECTION AMONG ADOLESCENT GIRLS AND YOUNG WOMEN AGED 15-24 YEARS IN UGANDA: DEVELOPMENT OF AN HIV-RISK REDUCTION MODEL FOR CENTRAL REGION
REFNo: HS2554ES

1) To determine the influence of behavioral and biological practices on the HIV Infection among AGYW in the Central region, Uganda.2) To assess the influence of socioeconomic factors on behavioral and biological practices associated with HIV Infection among AGYW in Central region, Uganda.3) To analyze the influence of structural factors on behavioral and biological practices associated with HIV Infection among AGYW in Central region, Uganda.4) To develop a multilevel HIV-Risk reduction model to facilitate the delivery of appropriate HIV prevention services responsive to the particular needs of the AGYW aged 15–24 years in the Central region, Uganda.
Uganda 2023-03-02 12:56:09 2026-03-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Ritwika Sen
ID:
Supervision and Productivity Dynamics: Evidence from a Field (Work) Experiment
REFNo: SS1612ES

To examine the direct effects of the supervision of survey enumerators on their learning and individual performance., Examine the impact of supervision on the performance of employees through two distinct channels: monitoring and feedback.,
India 2023-03-02 12:53:15 2026-03-02 Social Science and Humanities Non-Clinical Trial Degree Award
Diana  Ntamu Nandagire
ID:
Baseline survey for diverse and resilient livelihoods for youth and women from refugee and host communities in Isingiro and Lamwo districts
REFNo: SS1547ES

Main objective
To establish baseline status of the selected indicators for the Uthabiti project impact, outcome and outputs.


a)To provide initial values for the impact and outcome indicators disaggregated by gendered households as appropriate in the Uthabiti intervention areas, establishing target levels for improvements in these indicators over the three-year implementation period.

b)To provide more evidence to describe the prevailing conditions of the target communities or populations in terms of their socio-economic wellbeing and self-reliance and refine intervention. This will provide the consortium team a deeper understanding of the context to tailor the interventions as well understanding how well or not, the proposed theory of change aligns with the demonstrated need of the target population survey.


c)To provide Uthabiti baseline indicator values that can be compared with the endline indicator values to measure the level of changes and inform future programing,, and


d)To integrate gender and social inclusion throughout the review.

Uganda 2023-03-02 12:52:03 2026-03-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Raymond Atwine
ID: UNCST-2022-R011223
A clinicopathologic digital image platform to aid the diagnosis of breast cancer amongst patients at Mbarara Regional Referral Hospital.
REFNo: HS2606ES

i. To develop a digital platform that will be used to process and store breast lesion images, symptoms, and risk factors among women presenting at Mbarara regional referral hospital with breast lesions.
ii. To digitize gross and histology annotated images of breast lesions from patients presenting at Mbarara regional referral hospital
iii. To develop a machine learning model for diagnosis of breast cancer in patients presenting with breast lesions at Mbarara Regional Referral Hospital

Uganda 2023-03-02 12:50:32 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Kayemba Jonah
ID:
CLIMATE CHANGE ADAPTATION AND SUSTAINABLE LIVELIHOOD OF WOMEN IN AGRICULTURE IN BUSOGA SUBREGION, EASTERN UGANDA: THE MODERATING EFFECT OF POLICY IMPLEMENTATION
REFNo: SS1620ES

1. To examine Structural Climate Change Adaptation factors associated with sustainable livelihood of women in agriculture in the Busoga sub region, Eastern Uganda. 2. To assess Social Climate Change Adaptation factors associated sustainable livelihood of women in agriculture in the Busoga sub region, Eastern Uganda. 3. To determine Institutional Climate Change Adaptation factors associated with sustainable livelihood of women in agriculture in the Busoga sub region, Eastern Uganda. 4. To assess climate change policy implementation factors moderating in the relationship between climate change adaptation and the sustainable livelihood of women in agriculture in the Busoga subregion, Eastern Uganda.
Uganda 2023-03-02 12:49:17 2026-03-02 Social Science and Humanities Non-Clinical Trial Degree Award
Henry Twinomujuni Kafunjo
ID:
INDIGENOUS KNOWLEDGE AND INTELLECTUAL PROPERTY OF TRADITIONAL MEDICINE IN UGANDA
REFNo: SS1539ES

1) To assess the perceptions of traditional healers in Uganda on the use of an intellectual property system in the protection of traditional medicine knowledge.
2) To examine the suitability of an intellectual property system in protecting traditional medicine knowledge and practice.
3) To evaluate the factors that facilitate proper functioning of the intellectual property system in protecting traditional medicine knowledge and practice.

Uganda 2023-02-27 10:10:15 2026-02-27 Social Science and Humanities Non-Clinical Trial Degree Award
Monil Khera
ID:
Investigate the effect of climate on the behaviour and demography of banded mongooses (Mungos mungo).
REFNo: NS443ES

Understand how body temperatures change in relation to the surrounding climate and what behaviours they are performing.
UK 2023-02-27 10:06:38 2026-02-27 Natural Sciences Non-Clinical Trial Degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."