Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Bjorn Van Campenhout -
ID: UNCST-2020-R014080
Increasing Adoption and Varietal Turnover of Seed: Consumer and Producer Side Interventions
REFNo: SS1657ES

The study will be implemented through a cluster randomize control trial, where a sample of treatment villages (clusters) will receive producer side treatments (free seed trial packs or discounted seed trial packs of a poorly adopted improved maize variety, Bazooka) while other treatment villages will receive a consumer side intervention involving cooking and tasting demonstration of maize from the improved variety. However, in both treatment and control groups, we will inform farmers about the existence of the improved seed variety and the benefits of using them, to be able to isolate the effect of the trail pack from merely knowledge effects.
Belgium 2023-03-16 12:43:52 2026-03-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jennifer  Kealy
ID:
Community Engagement in Paediatric Biobanking Governance in Uganda.
REFNo: SS1651ES

The aim of this study is to provide IARC and the Ugandan Government with actionable recommendations concerning the development of paediatric biobanking guidelines. The primary objective is to identify the key ethical issues/concerns for researchers, laboratory staff, and health authorities in Uganda, specifically related to public trust in biobanking, and how trust/ trustworthiness could be addressed in paediatric biobanking governance as well as how the community might be engaged.
• Does it hold true that trust/ trustworthiness is contextual and that effectively would preclude any harmonisation of guidelines for biobanking? Or is there any common ground on which to build global /international guidelines,
• What are the gaps in biobanking in Uganda, particularly with respect to paediatric biobanking and,
• How can Uganda create paediatric biobanking guidelines that reflect the needs identified by communities and what would this look like, and,
• How can biobanks show they are trustworthy through their governance and what does that look like to Uganda? Is it sufficient to be transparent and accountable or are other cultural/economic/religious/aspects that parents consider in their assessment of trust in a biobank?
• How can ethical considerations related to biobank governance be addressed in an inclusive, collaborative and deliberative manner

USA 2023-03-16 12:41:09 2026-03-16 Social Science and Humanities Non-Clinical Trial Degree Award
Jennifer Verdolin
ID:
Establishing a Long-Term Behavioral and Ecological Monitoring Research Program in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park
REFNo: NS500ES

1) Understand the factors contributing to within and between group variability in parasite infection and transmission; 2) Characterize the diet of mountain gorillas across different habitats in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park; 3) Explore habitat use and spatial dynamics of mountain gorillas in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park; 4) Collaborate with UWA to yield insights critical for the protection and management of mountain gorillas and other species in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park; 5) Characterize the biodiversity of Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park, including genomics of multiple species using opportunistically collected fecal samples. These species include but would not be limited to forest elephants and pangolins.
USA 2023-03-16 12:39:44 2026-03-16 Natural Sciences Non-Clinical Trial Non-degree Award
Florence Kyoheirwe Muhanguzi
ID: UNCST-2021-R002777
Building women smallholder farmers’ empowerment and adaptive capacities: A pathway to enhancing women’s resilience to climate change in Uganda
REFNo: SS1660ES

General objective
● To strengthen the empowerment and adaptive capacity of women smallholder farmers in the cattle corridor of Uganda using gender transformative approaches.

Specific objectives
1. Establish women smallholder farmers’ levels of empowerment and adaptive capacities to the effects of climate change;
2. Assess the social cultural gender norms, economic and political trade-offs and barriers to empowerment and climate adaptation by women smallholder farmers;
3. Design and test a mix of gender transformative climate change adaptation innovations that are effective in enhancing women smallholder farmers’ empowerment and resilience to the effects of climate change.
4. Advocate for policies and practices that enhance women smallholder empowerment and adaptive capacities to climate change shocks.

Uganda 2023-03-16 12:37:54 2026-03-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
Phase IIa Proof of Concept, Multicenter, Randomized, Open-label Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of the Combination M5717 plus Pyronaridine Administered once Daily for 1 or 2 Days to Adults and Adolescents with Acute Uncomplicated Plasmodium falciparum Malaria
REFNo: HS2736ES

To evaluate the safety and
tolerability of the M5717-
pyronaridine combination in
adult participants with acute
uncomplicated malaria due to
P. falciparum.
Secondary.
o describe the clinical efficacy
of the M5717-pyronaridine
combination in adult participants
with acute uncomplicated
malaria due to P. falciparum
Uganda 2023-03-16 12:35:56 2026-03-16 Medical and Health Sciences Clinical Trial Non-degree Award
Charles Masembe Kikubo
ID: UNCST-2019-R001092
The Dispersal of Antibiotic Resistance and Antibiotics in Water Ecosystems and Influence on livestock and Aquatic wildlife (PAIRWISE)
REFNo: A240ES

i) To investigate the dispersal of Antibiotic Resistant Bacteria (ARB), Antibiotic Resistant Genes (ARG) and Antibiotics (ATB) in surface waters downstream of WWTPs ii) To investigate the carriage of ARB and ARG in livestock linked to surface waters influenced by WWTPs iii) To ascertain the role of aquatic birds in dispersal of ARB and ARG
Uganda 2023-03-09 23:54:51 2026-03-09 Agricultural Sciences Non-Clinical Trial Non-degree Award
Francis Garuzooka John
ID:
Investment practices of persons with a disability in informal microfinance groups in Uganda
REFNo: SS1617ES

1. Examine the attitudes of persons with a disability regarding investment, saving and borrowing from VSLAs and ROSCAs in selected districts in Uganda. 2. Analyse what influences the persons with a disability’ investment choices as individuals and members of groups (Revised as: Analyse what influences persons with disabilities’ investment choices as individuals and as members of groups.) 3. Explain how persons with a disability acquire the knowledge and skills they use while investing resources obtained from VSLAs and ROSCAs. 4. Describe the experiences that persons with a disability have regarding investment of loans obtained from VSLAs and ROSCAs in selected districts in Uganda.
Uganda 2023-03-09 23:52:14 2026-03-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bonniface Oryokot
ID:
Adaptation and Evaluation of the Operation Triple Zero (OTZ) model to improve Retention and HIV viral suppression among the Adolescents Living with HIV in TASO Uganda using the RE-AIM framework.
REFNo: SS1610ES

• To implement and test the adapted OTZ intervention from January 2023 to end of August 2023.,• To adapt and design the OTZ model to the TASO Uganda context,• To determine the barriers and facilitators to Retention and VLS,• To improve health outcomes among CALHIV in selected TASO Uganda COEs.,
Uganda 2023-03-09 23:48:16 2026-03-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSAPHAT KAYOGOZA BYAMUGISHA
ID: UNCST-2019-R001680
Observational study on management of post-partum haemorrhage at Kawempe National Referral Hospital (REBOA-PPH baseline study)
REFNo: HS2730ES

To suggest a customized training to improve PPH management in a large referral hospital in Uganda,To identify specific areas of potential improvements in PPH management,To describe the actions taken in the process of managing PPH among mothers admitted to KNRH,To describe the current management of severe PPH with timelines from identification until bleeding is controlled,To map the occurrence of severe PPH among birthing mothers admitted at Kawempe National Referral Hospital (KNRH),The aim of this study is to map the occurrence of severe post-partum haemorrhage (PPH) and its current management and to identify potential improvements in the management of severe PPH in a large referral hospital in Uganda. ,
Uganda 2023-03-09 23:43:20 2026-03-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
EZRA BYAKORA
ID: UNCST-2022-R009194
Investigating the enhancement of Nile tilapia breeding in Uganda through integration of modern aquaculture breeding and genetics tools
REFNo: A269ES

1)Support NAGRC&DB to improve its Nile tilapia breeding program via establishing individual fish identification and phenotyping system.
2)Investigate genetic health and diversity of Uganda’s farmed Nile tilapia breeding population in comparison to their wild relatives in the three major lakes (L. Victoria, L. Kyoga and L. Albert) in Uganda.
3)Estimate genetic parameters of key production traits (including growth rate, body length and harvest weight).
4)Identify genomic regions associated with production traits.
5)Investigate potentials of integrating genomic tools into selective breeding for improving Nile tilapia in Uganda.

Uganda 2023-03-09 23:41:58 2026-03-09 Agricultural Sciences Non-Clinical Trial Non-degree Award
Carolyn Pelnik
ID:
School Management and Re-Enrolling Dropouts: Experimental Evidence from Schools in Rural Uganda
REFNo: SS1656ES

Which version of the program is more cost-effective in terms of gains to student learning: an intervention that assigns highly qualified university graduates to partner with community members to implement enrollment and remedial education activities, or an intervention where enrollment and remedial education activities are executed by community members alone? ,What is the effect of a school management intervention targeted towards the head teacher on school inputs (administrator time use and other measures of school functionality such as teacher attendance) and outputs (enrollment and learning, as measured by literacy and numeracy test scores)?,
USA 2023-03-09 23:39:42 2026-03-09 Social Science and Humanities Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
A Phase 2/3, Multicenter, Open-label, Multicohort Study Evaluating Pharmacokinetics (PK), Safety, and Efficacy of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in HIV-1 Infected, Virologically Suppressed Pediatric Participants.
REFNo: HS2646ES

The primary objective of this study is to confirm the dose of ATV/co or DRV/co in HIV-1 infected pediatric participants, to confirm the dose of F/TAF in HIV-1 infected pediatric participants and to evaluate the safety and tolerability these medications.
Uganda 2023-03-09 23:33:04 2026-03-09 Medical and Health Sciences Clinical Trial Non-degree Award
Pooja Chitneni
ID: UNCST-2021-R012955
Developing an STI partner notification services delivery intervention in southwestern, rural Uganda.
REFNo: HS2720ES

Explore facilitators and barriers to task-shifting delivery models for STI partner notification among healthcare workers, administrators, and potential patients. Also to develop a novel STI partner notification services delivery intervention for Uganda and similar settings.
USA 2023-03-09 22:41:48 2026-03-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph  Kampumure
ID:
FINANCIAL LITERACY, SELF-EFFICACY AND FINANCIAL INCLUSION AMONG WORKING WOMEN IN UGANDA
REFNo: SS1474ES

i) Establish the effect of financial literacy on financial inclusion among working women in Uganda. ii) Establish the effect of financial literacy on self-efficacy among working women in Uganda. iii) Determine the effect of self-efficacy on financial inclusion among working women in Uganda. iv) Determine the effect of self-efficacy on the connexion between financial literacy and financial inclusion among working women in Uganda.
Uganda 2023-03-07 11:05:55 2026-03-07 Social Science and Humanities Non-Clinical Trial Degree Award
Jiseon Chang
ID:
Empowering Developing Countries: Combating Misinformation and Correcting (Mis)perceptions of Foreign Aid
REFNo: SS1545ES

Understand how and when are perceptions of aid created
South Korea 2023-03-07 11:04:27 2026-03-07 Social Science and Humanities Non-Clinical Trial Degree Award
Patricia Ndugga
ID: UNCST-2022-R009605
Parent-adolescent communication on sexual and reproductive health in Kyotera border district, Central Uganda
REFNo: HS2702ES

The main objective of this study is to investigate the practice of SRH communication between parents and adolescents in Kyotera district, Central Uganda., 1. To determine the prevalence and factors associated with parent adolescent communication about SRH in Kyotera district. A cross-sectional survey for both parents and children will be conducted to establish the proportion of parents / children who discuss SRH issues, 2. Explore the approaches to, content and frequency of SRH communication between parents and adolescents in Kyotera., 3. To assess the community and district level stakeholders’ recommended strategies for improving communication of SRH between parents and adolescents.,
Uganda 2023-03-07 10:57:19 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
COVID-19 vaccine effectiveness and variants in Uganda: a test-negative case-control study with genetic sequencing (COVVAR)
REFNo: HS2672ES

Primary Objective To estimate vaccine effectiveness of licensed COVID-19 vaccines against laboratory-confirmed COVID-19 disease. Secondary Objectives 1. To identify circulating SARS-CoV-2 variants in Uganda. 2. To estimate vaccine effectiveness against specific SARS-CoV-2 variants identified by genetic sequencing. 3. To estimate vaccine effectiveness against severe COVID-19 disease. 4. To estimate effectiveness of COVID-19 vaccines against different SARS CoV-2 variants and different COVID-19 disease severities. Exploratory objective 1. To evaluate disease severity due to different circulating SARS CoV-2 variants
Uganda 2023-03-07 10:53:48 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DENIS MUGIZI RWABIITA
ID:
Assessment of meat handler training interventions on hygiene and disease detection in Ugandan slaughterhouses and meat retail outlets
REFNo: A266ES

Use syndromic surveillance to understand the incidence and distribution of important animal and zoonotic disease in Uganda,Assess the impact of mobile training tool on meat inspector knowledge,Assess the impact of nudges on knowledge and practices and food contamination at pork retail,Assess the impact of a targeted meat handler training on the knowledge, attitudes, and practices of meat handlers in Uganda.,
Uganda 2023-03-07 10:50:39 2026-03-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Raymond Tweheyo
ID: UNCST-2020-R014507
Understanding the effect of varied financial compensation structure for improving the performance, motivation and retention of Community Health Workers in Uganda - a quasi experiment
REFNo: HS2689ES

General objective: To understand the effect of varied financial compensation structure for improving the performance, motivation and retention of Community Health Workers in Uganda.

Specific objectives:
1. To determine the optimal performance based financial incentive incentive's structure required for improving the performance, motivation and retention of CHWs.

2. To explore the acceptability and perceptions of potential sustainability of CHWs financial compensation structure to various stakeholders, including the CHWs, and the CHW supervisors at the district and Ministry of Health.

3. To explore the perceived value and impact of financial incentives on CHW's job satisfaction, personal income and livelihood.
UK 2023-03-07 10:40:31 2026-03-07 Medical and Health Sciences Clinical Trial Non-degree Award
Stephen  Ojiambo Wandera
ID: UNCST-2021-R012147
Assessing Dementia and Frailty among Older Persons in selected rural districts in Eastern Uganda
REFNo: HS2693ES

Therefore, the aim this study is to determine the prevalence of frailty and dementia among older persons in rural Uganda. Specific aims of the study include:
Aim 1: To estimate the prevalence and factors associated with dementia among older persons in Uganda.
Aim 2: To estimate the prevalence and factors associated with frailty among older persons in Uganda.
Aim 3: To explore the experiences and perceptions of caregivers of older persons with dementia in Uganda.
In this study, we refer to point prevalence only.

Uganda 2023-03-07 10:36:00 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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