Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Margaret Nafuna Sarah
ID:
EXAMINING MOTIVATIONAL STRATEGIES INFLUENCING PERFORMANCE OF TUTORS IN CORE PRIMARY TEACHERS’ COLLEGES IN EASTERN UGANDA
REFNo: SS1647ES

3. To analyse the challenges that may influence the effective motivation of tutors in Core PTCs in Eastern Uganda.,2. To examine the views of tutors on how motivational strategies affect their performance in Core PTCs in Eastern Uganda.,1. To investigate motivational strategies employed in Core PTCS in Eastern Uganda. ,
Uganda 2023-04-04 9:36:11 2026-04-04 Social Science and Humanities Non-Clinical Trial Degree Award
Milcah Abasabyona
ID:
Intimacies of Identification and Lived Citizenship among the Ghetto Youths in Kampala, Uganda
REFNo: SS1654ES

Main Objective:
To investigate how citizen certification and identification influences levels of belonging to a place and space, impacts on citizen-state relationship and individual personhood.
Specific Objectives:
1. To capture the individual practical experiences of legal certification and identification processes among the Ghetto youths.
2. To examine the regulatory effects of identification documents on citizenship rights, a sense of belonging, and personhood among the Ghetto youths in Kampala.
3. To explore the different key Identification documents and their role in the day to day lives of the Ghetto Youths.
4. To trace the ways in which the undocumented Ghetto youths create alternative routes to lived citizenship and self-certification.
Uganda 2023-04-04 9:32:41 2026-04-04 Social Science and Humanities Non-Clinical Trial Degree Award
ANYASE AMAZA RONALD
ID: UNCST-2022-R009325
Development of a Natural Anti-Aflatoxin Product
REFNo: HS2692ES

To develop a prototype natural based anti-aflatoxin product made from Ugandan plants.,To establish a database of plants in Uganda with anti-aflatoxin potential,To determine the indigenous approaches of aflatoxin control in Uganda.,To develop a natural based anti-aflatoxin product ,
Uganda 2023-04-03 21:04:19 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
Professional Identity of Ugandan Nurses and Midwives: Exploring the understanding, Perceptions and Experiences among student Nurses and Midwives, Recent Graduates and Nurse Educators
REFNo: HS2712ES

Explore nurse and midwife top management in the ministry of health and nurses and midwives council perception and experiences fostering professional identity in nursing in the country.,3. Explore nurse and Midwife educators’ perceptions and experiences fostering professional identity in nursing and midwife at Mbarara University of Science and Technology and Makerere university,2. Explore challenges and barriers to professional identity formation at Mbarara University of Science and Technology and Makerere University,1. Describe the understanding of the professional identity of final year undergraduate nurses and midwives and recent graduates at Mbarara University of Science and Technology and Makerere University.,
Uganda 2023-04-03 21:00:42 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
zaina Nakabuye
ID:
Technology orientation and the export performance of SME exporting firms in Uganda.
REFNo: SS1472ES

2. To establish the relationship between knowledge absorptive capacity and export performance.
3. To examine the relationship between supply chain agility and export performance.
4. To investigate the moderation of knowledge absorptive capacity between technology orientation and export performance.

5. To investigate the moderation of supply chain agility between technology orientation and export performance.

Uganda 2023-04-03 20:58:43 2026-04-03 Social Science and Humanities Non-Clinical Trial Degree Award
Pooja Chitneni
ID: UNCST-2021-R012955
Development and assessment of an HIV disclosure intervention for men in Uganda - Aim 1
REFNo: HS2682ES

Aim 1. Identify the unique HIV disclosure needs and preferences among MWH to support HIV disclosure. ,
USA 2023-04-03 20:55:31 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
Prevalence of and factors associated with mental disorders and coping mechanisms among students at Busitema University.
REFNo: HS2700ES

To explore factors influencing mental disorders among students at Busitema UniversityTo explore the coping mechanisms used by students at Busitema University
Uganda 2023-04-03 20:53:26 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
Qualitative research to prepare for novel HIV prevention products
REFNo: HS1749ES

Define a preliminary strategy for the integration of novel PrEP products (e.g., injectable Cabotegravir, Dapivirine intravaginal ring, TFV/LNG intravaginal ring) into existing oral PrEP programs by conducting qualitative interviews with experts in novel PrEP products, oral PrEP programs, and end users.
To achieve this aim, we will conduct approximately 60 key informant interviews (KII) with: 1) clinical trialists leading studies of novel PrEP products, 2) oral PrEP program leaders in sub-Saharan Africa and 3) young women in Uganda who have decided not to use oral PrEP during recent PrEP studies.

Uganda 2023-04-03 20:51:28 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
Prevalence of intestinal colonization by ESBL-producing Enterobacterales in neonates at Jinja Regional Referral Hospital
REFNo: HS2737ES

• To highlight the area of antibiotic resistance in neonates in this setting ,• To conduct a point-prevalence surveillance of ESBL-producing Enterobacterales in the neonatal unit at two specific time-points with two weeks apart.,The overall aim of this project is to create base-line data for future infection prevention control strategies in the area of newborn care at Jinja Referral Hospital.,
Uganda 2023-04-03 20:49:30 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stella Maris Nanyonga
ID:
Optimizing antimicrobial use in the management of Upper Respiratory Tract Infections through antimicrobial stewardship in Community Pharmacy practice in Uganda; A patient centered approach
REFNo: HS2617ES

Primary Objectives 1. To assess the knowledge, attitude, and practice (KAP) towards self-medication among patients who visit community pharmacies for the management of Upper respiratory tract infections. 2. To explore the barriers and facilitators of self-medication in the community. 3. To explore prescriber views and understanding on the use of delayed prescribing in primary care. Secondary Objectives 4.To evaluate the effectiveness of training and delayed prescribing intervention on antibiotic consumption among patients with URTI who visit community pharmacies. 5. To describe dispensing and prescribing patterns of pharmacy staff when managing patients with upper respiratory tract infections at the community pharmacy
Uganda 2023-04-03 20:46:30 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Kakayi Catherine
ID: UNCST-2022-R008787
Insulin-like Growth Factor/Growth Hormone Levels and Stunting in HIV Exposed Uninfected Children from the 1077BF/P1084s study (CHASE: Changes in IGF/Hormone Axis and Stunting in HIV-Exposed uninfected children.
REFNo: HS2686ES

1. To investigate IGF-1, IGFBP-1, and IGFBP-3 as predictors of growth faltering/stunting in the first 2 years of life in HEU children

2. To describe the concentrations of hormonal growth factors in infants in relation to infant growth percentile at birth, 26 weeks, and 74 weeks of age.

Uganda 2023-04-03 20:41:44 2026-04-03 Medical and Health Sciences Clinical Trial Non-degree Award
Gerald Bareebe
ID:
Violence and Regime Trajectories in Post-Conflict Uganda and Rwanda
REFNo: SS1413ES

This study is driven by two important objectives: the first is the need to consider the influence of a “residue” social structure. What the cases of Uganda and Rwanda tell us is that, without understanding the underlying socio-political agency of the political regime and the armed elites that run it (and without knowing who their allies are or what the sources of constraints in that process are), it is difficult to resolve the socio-political problems that trouble most postwar states on the continent. The second is the need to show how post-war reconstruction in Africa is a function of elite interactions. The failure to understand this phenomenon has left post-conflict societies more vulnerable to conflict relapse. By investigating the interface of power elites in post-war state reconstruction, this research situates itself within a more empirical and contemporary African perspective and elevates the importance of social actors, specifically those whose actions reflect the intractability of power struggle. Specifically, the research seeks to achieve the following objectives:

 To understand the process of post-conflict state reconstruction in Uganda and Rwanda
 To understand factors that may hinder or enable the rebuilding of state institutions after a civil war.
 To compare the experience of Uganda and Rwanda with regards to how they both approached state reconstruction after a devastating civil war.
 To determine the nature and impact of policies taken by state-builders in both Uganda after the 1986 civil war and Rwanda after the 1991 genocide.

Uganda 2023-04-03 16:49:25 2026-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Timothy Allen Peter
ID: UNCST-2019-R001369
Public Authority and International Development Uganda Programme Phase 2
REFNo: SS1678ES

Inductive theory-building through comparative applications,New curriculum development for scholars and development professionals,Reciprocal capacity-building in the academy and knowledge production,Reflexive policy-making and governance impact,Generate impact, knowledge exchange and capacity building through a public authority lens,
UK 2023-04-03 16:41:36 2026-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jesse Rudy Lynn
ID: UNCST-2023-R008208
Prevalence of property Grabbing among widows in Uganda
REFNo: SS1677ES

To establish the total number of people protected in the different project areas districts as a result of Redeem’s program interventions., 1)To understand the indirect consequences of attempted and successful land/property grabbing for widows and orphans in the aftermath of the events, 2)To ascertain the criminal, violent or other means used by perpetrators to victimize widows and orphans through grabbing property or land in Uganda., 3)To determine the prevalence of property grabbing from widows in targeted areas of Uganda, 4)To measure the annual burden of property grabbing in the selected case work areas ,
USA 2023-04-03 15:40:08 2026-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
GRACE MARY KENYONGA
ID:
Attitudes towards the use of pre-exposure prophylaxis for HIV among women in Uganda
REFNo: SS1473ES

General aim
Examine the attitudes towards the use of pre-exposure prophylaxis for HIV among women in Uganda.
Specific Objectives
1. Explore the attitudes women have towards PrEP
2. Identify the factors that influence the present attitudes towards PrEP
4. Identify other community variables that may encourage or constrain the uptake of PrEP.
6. Identify and recommend necessary interventions and measures to counteract any prevailing negative attitudes towards PrEP that may be prevailing in the community.

Uganda 2023-03-28 1:00:59 2026-03-28 Social Science and Humanities Non-Clinical Trial Degree Award
Alison Elliott
ID: UNCST-2023-R006524
Risk factors for severe schistosomal morbidity: an adult case-control study by the Uganda Schistosomiasis Multidisciplinary Research Centre (U-SMRC)
REFNo: HS2570ES

We hypothesise that factors at each step of the parasite life cycle interact to determine morbidity in schistosomiasis. The objective of this work is to investigate risk factors associated with advanced schistosomiasis morbidity among adults, using a case-control study.
UK 2023-03-24 2:35:04 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Birungi Edwin Mutahunga Rwamatware
ID: UNCST-2021-R004880
Prevalence and predictors of antimicrobial resistance in clinical- and community-acquired upper respiratory bacterial samples in children under 5 in south-western Uganda
REFNo: HS2625ES

Upper respiratory infections are the second leading cause of death in children under 5 in Uganda, and account for 40% of all under-5 outpatient attendance at clinics and hospitals nationwide in Uganda. As bacterial cultures of lung aspirates are often not practical, the WHO recommends using a rapid breathing and chest wall in-drawing to diagnose pneumonia in children under 5, and recommends treatment with oral amoxicillin or co-trimoxazole, or intramuscular penicillin. The only study of anti-microbial resistance (AMR) in nasopharyngeal bacteria in Uganda comes from healthy children in the Iganga/Mayuge region (Eastern Uganda), where the authors found that one-third of children were given a self-prescribed antibiotic within the past two weeks for fever, running nose, or cough, that 60% carried Streptococcus pneumoniae, and that a high proportion (80% to 99%) of cultures were resistant to co-trimoxazole, penicillin, and oxacillin. At Bwindi Community Hospital, suspected acute respiratory infections accounted for 75% of all under-5 outpatient diagnoses in 2015/2016, and are the most common reason for under-5 admissions to the Pediatrics Ward (e.g., 34% of 830 admissions in 2015/2016). In addition, the majority of antibiotics prescribed for both children and adults were for suspected acute respiratory illness (5,273 of 17,910 prescriptions). Our proposed study seeks to build on previous work concerning Antimicrobial Resistance in the developing world with a specific focus, on clinical- and community-acquired upper respiratory bacterial infections in children under 5 in southwestern Uganda, and it will be the first to analyse spatio-temporal patterns of resistance and explicitly link those patterns to cultural and social characteristics and behaviours on the ground as well as healthcare infrastructure. We propose a multi-layered study to; 1) Analyze the prevalence and spatial associations of antibiotic resistance in nasopharyngeal bacterial isolates from children under 5 in the Bwindi Community Hospital (BCH) catchment area for a year in Kanungu District, Southwestern Uganda. 2) Assess the use of antibacterial drugs at home to treat acute respiratory illness in these children from children under 5 in the Bwindi Community Hospital (BCH) catchment area in Kanungu District 3) Assess practices of antibiotic distribution at drug shops in the BCH catchment region.
Uganda 2023-03-24 2:31:31 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
Investigating determinants of varying schistosomal morbidity among preschool-age children in the Lake Albert and Lake Victoria regions: a cohort study by the Uganda Schistosomiasis Multidisciplinary Research Center
REFNo: HS2568ES

Our main objective is to understand the biological determinants of severe Schistosoma mansoni-associated morbidity and to identify better strategies for its prevention and control. Our specific objectives are to: 1. Compare, in pre-school age children, early-life Sm infection and Sm-specific immune responses between Lake Albert and Lake Victoria regions and identify co-exposures that modulate Schistosoma mansoni-specific immune responses and morbidity risk 2. Determine if there is a parasite genetic basis for differential Schistosoma mansoni morbidity 3. Determine how the population biological determinants of fresh-water snail Biomphalaria spp. act as local epidemiological drivers of Schistosoma mansoni
UK 2023-03-24 2:29:21 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olive Kobusingye Chifefe
ID:
Building the evidence-base for the integration of rehabilitative services into health systems – a case study of clubfoot treatment in Uganda
REFNo: HS2614ES

The study has two aims, each with subsequent research questions: Aim 1: To explore how policy makers, health providers, and caregivers define, understand and experience service integration and the potential implications for clubfoot treatment. (Qualitative) • How do health care providers define and experience service integration, and what are the impacts of integration on their day-to-day clinical operations, workflow, and roles? • How do district- and national-level bureaucrats and donors understand integration, and how does that shape integration of clubfoot treatment? • How do caregivers understand and experience integration, and how does it impact their child’s treatment? • How is the NCPU financed and what relationship does financial contribution have with integration? Aim 2: To improve understanding of how the CAST mobile health application (CAST) impacts health providers’ behavior, and what potential impacts the CAST could have on service quality. (Mixed) • What is the reach and adoption rate of CAST and its components among eligible Ugandan providers? • How might CAST modify provider behavior at the facility level, both for clubfoot treatment and other services? • How might the CAST facilitate quality of care and patient treatment? o How do supportive services from MiracleFeet/CoRSU contribute to this? (e.g. training, supportive supervision, help desk) o How does data from and usage of the Cast Community contribute to this? • What is the potential future of the CAST if external support is withdrawn from clubfoot treatment and all services are fully managed by the public sector?
Uganda 2023-03-24 2:25:26 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent Rheumatic Heart Disease: A non-inferiority randomized trial. (GOALIE)
REFNo: HS2659ES

Primary Objective:
To compare the proportion of children aged 5-17 years with latent RHD receiving oral penicillin prophylaxis who progress to worse valvular disease at 2-years compared to children who receive IM penicillin prophylaxis.

Uganda 2023-03-24 2:23:26 2026-03-24 Medical and Health Sciences Clinical Trial Non-degree Award
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