Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
juliet cheptoris
ID:
Experiences and perceptions of Intimate Partner Violence (IPV) among Adolescent Girls and Young Women (AGYW) enrolled in the DREAMS Project in Mukono District, Uganda, 2023
REFNo: SS1718ES

General study objective To explore experiences and perceptions of Intimate Partner Violence (IPV) among Adolescent Girls and Young Women (AGYW) 15-24 enrolled in the DREAMS Program in Mukono District Specific Objectives 1. To explore the knowledge and perceptions on IPV among Adolescent Girls and Young Women (AGYW) who are enrolled in the DREAMS program 2. To examine the experiences of IPV among AGYW before and after enrolling in the DREAMS program. 3. To determine the factors associated with Intimate Partner Violence among AGYW who enrolled in the DREAMS program.
Uganda 2023-05-25 12:08:46 2026-05-25 Social Science and Humanities Non-Clinical Trial Degree Award
Rosalind  Parkes-Ratanshi Parkes
ID: UNCST-2019-R000717
HIV and sexually transmitted infection international biorepository and diagnostic test performance
REFNo: HS2724ES

• To create a biorepository to test retrospectively the performance of investigational, emerging diagnostic technologies in the intended population or setting compared to a reference comparator for diagnosing HIV/STIs using frozen samples.
• To test prospectively the accuracy of investigational, emerging diagnostic technologies in the intended population or setting compared to a standard comparator for diagnosing HIV/STI infection
• To determine agreement between self-collected swabs, saliva and clinician-collected swab samples for the diagnosis of STI using a reference test in Uganda.
• To determine agreement between self-collected blood, saliva and clinician-collected blood samples for the diagnosis of HIV using a reference test in Uganda.
• Determine the proportion of non-reportable results (unresolved, indeterminate and incomplete) and turn-around time compared to reference test.
• To assess acceptability of self-collected blood samples, swab tests, and saliva for testing HIV/STI in both participants and healthcare workers in Uganda.
• To explore socio-demographic, behavioural and clinical factors associated with positive HIV and other STI diagnosis

UK 2023-05-25 12:07:08 2026-05-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Idro
ID: UNCST-2021-R013599
Dihydroartemisinin-piperaquine and azithromycin for the post-discharge management of children with severe anaemia in Malawi, Kenya and Uganda; A, multicentre, parallel-group, two-arm, randomised, double-blind superiority trial.
REFNo: HS2815ES

To determine if PDMC with four courses of monthly AZ treatment in combination with four months of weekly DP is superior to PDMC with weekly DP-alone in reducing non-malaria SCCV by six months post-discharge in children aged <5 years admitted with severe anaemia (Hb<5g/dl) who are ready to be discharged and are clinically stable and able to switch to oral medication,
Uganda 2023-05-25 12:04:54 2026-05-25 Medical and Health Sciences Clinical Trial Non-degree Award
David Meya Bisagaya
ID: UNCST-2019-R000837
Platform Trial For Cryptococcal Meningitis - PLATFORM-CM
REFNo: HS2649ES

The purpose of this study is to know whether this oral form of amphotericin (MAT2203) is safe and effective in the treatment of people sick with cryptococcal meningitis.
Uganda 2023-05-25 12:01:51 2026-05-25 Medical and Health Sciences Clinical Trial Non-degree Award
CHRISTINE MBABAZI -MPYANGU
ID:
Freedom of Religion or Beliefs Leadership Network (FoRBLN): A case study of Tororo district in Uganda.
REFNo: SS1308ES

Overall goal To explore a new synthesis of theoretical models derived from a combination of work in cognitive anthropology with modes theory, social psychology with identity fusion, leadership psychology with barrier crossing leadership. The research aims to address the following research questions 1. What role do imagistic group experiences play in fostering identity fusion Vs group identification bonds directed at the ingroup vs outgroup. 2. How far attitudes towards and experiences of barrier crossing leadership lead to improved intergroup attitudes and behaviours. 3. Whether individual empathetic abilities moderate the effects of imagistic experiences and/ or barrier crossing leadership. 4. How far the evidence from the cross cultural sample supports the theoretical model outline by modes theory.
Uganda 2023-05-25 11:59:07 2026-05-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
JULIET MWANGA-AMUMPAIRE
ID: UNCST-2022-R009420
Omuyambi: Traditional healer support to improve HIV viral suppression in rural Uganda
REFNo: HS2780ES

Aim 2: Evaluate implementation of the Omuyambi intervention using a convergent, mixed methods study design guided by the Consolidated Framework for Implementation Research (CFIR). Participants for this Aim will include TH and PLWH from Aim 1, in addition to staff from affiliated HIV clinics, and Ministry of Health (MoH) AIDS Control Division Officers who will be invited to participate in in- depth interviews and structured surveys. Following the convergent mixed methods approach38, quantitative and qualitative data – including validated survey instruments, in-depth interviews, and structured observations – will be collected to evaluate context pertinent to Omuyambi implementation over a 24-month period.,Aim 1: We will compare the Omuyambi intervention versus HIV clinic-based care (control) in a cluster randomized trial to assess the effectiveness of a community-based traditional healer (TH)-facilitated support program for people living with HIV (PLWH) in Mbarara District. We will conduct a CRT of Omuyambi versus TH’s referrals for clinic-based HIV care at 40 TH cluster sites over 33 months in Aim 1. The unit of randomization is the TH; each cluster includes TH and adult PLWH who are ART naïve or defaulted from HIV care. TH who are randomized to Omuyambi will facilitate HIV support for ART naïve or nonadherent PWLH receiving care at their practice.,We propose a parallel arm cluster randomized trial to compare the intervention (Omuyambi) to the control in Aim 1 to assess the effectiveness of the intervention and use a mixed methods approach to evaluate the implementation in Aim 2.,
Uganda 2023-05-18 16:44:40 2026-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gideon Nsubuga
ID:
Inflammageing and anti-inflammageing cytokines in the HIV-seropositive and HIV-seronegative geriatric populations in Uganda.
REFNo: HS2889ES

1) To determine the mean inflammageing and anti-inflammageing cytokine levels in HIV-seropositive compared to HIV-seronegative geriatric populations in Uganda. 2) To determine the risk factors for inflammageing and anti-inflammageing cytokines in the HIV-seropositive compared to the HIV-seronegative geriatric population in Uganda.
Uganda 2023-05-18 16:05:34 2026-05-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Margaret Lubwama
ID: UNCST-2019-R000636
Antimicrobial resistance training course for preclinical undergraduate health sciences students in Makerere University
REFNo: HS2831ES

Increase knowledge of AMR among preclinical undergraduate health sciences students at MakCHS,To develop and execute a blended AMR training course curriculum for preclinical undergraduate health sciences students at MakCHS,To determine the knowledge gap about AMR among clinical undergraduate health sciences students at MakCHS ,To improve knowledge about AMR among preclinical undergraduate health sciences students at MakCHS
Uganda 2023-05-18 16:03:18 2026-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Justine Bukenya Nnakate
ID: UNCST-2021-R012503
Multi-City Menstruation-Friendly Public Toilet (MFPT) Study
REFNo: HS2796ES

General objective
To describe public toilets in Kampala city and identify approaches to improve their menstrual health and hygiene (MHH) compatibility (or “friendliness”)

Specific objectives
• To describe public toilets and their menstrual health and hygiene (MHH) compatibility (or “friendliness”) in Kampala city.
• To identify approaches to improve their menstrual health and hygiene (MHH) compatibility (or “friendliness”) in Kampala city.

Uganda 2023-05-18 16:02:21 2026-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Wamimbi Wotti
ID:
DEMOCRACY HUMAN RIGHTS AND GOVERNNANCE LEARNING, EVALUATION, AND RESEARCH (DRG-LER) II ACTIVITY GENDER-BASED VIOLENCE PORTFOLIO PERFORMANCE EVALUATION
REFNo: SS1709ES

To understand what is working, challenges faced, knowledge gaps, and what can be improved in USAID/GenDev’s GBV portfolio - RISE Activity Cluster,
Uganda 2023-05-18 16:01:29 2026-05-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Amon Kanyesigye
ID:
KNOWLEDGE OF SICKLE CELL DISEASE AND ASSOCIATED FACTORS AMONG UNDERGRADUATE STUDENTS AT MAKERERE UNIVERSITY
REFNo: HS2823ES

1.To determine knowledge and awareness levels of SCD among undergraduate students at
Makerere University.
2. To determine the factors associated with knowledge and awareness levels of SCD among
undergraduate students at Makerere University.
Uganda 2023-05-18 16:00:11 2026-05-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Yume Nomoto
ID:
A comparison of nutritional status among children under five years of age between refugee and host communities: A multi-sectoral cross-sectional study in Lamwo district, Uganda
REFNo: SS1640ES

To estimate determinants of nutritional status among children in refugee and host communities,To estimate the difference in the prevalence of malnutrition among children between refugee and host communities,To estimate the difference in nutritional status among children 0-59 months of age between refugee and host communities.,
Japan 2023-05-18 15:50:51 2026-05-18 Social Science and Humanities Non-Clinical Trial Degree Award
Patrick Tumwine
ID:
An Exploration of How Education Stakeholders Perceive the Implication of Grade Repetition at a Secondary School Level in Western Uganda. A Qualitative Multiple-Case Study.
REFNo: SS1727ES

To establish the parents' and administrators' perceptions about the cost implications of grade repetition within the secondary education system in Western Uganda.

To describe the teachers' and administrators' perception of the current grade repetition system's impact on students' self-efficacy.

To establish the understanding of administrators and chairpersons of PTA on the impact of grade repetition on national examination pass rates and related social promotion policy implications.
Uganda 2023-05-18 15:49:44 2026-05-18 Social Science and Humanities Non-Clinical Trial Degree Award
franck Sikakulya
ID: UNCST-2021-R013687
Effectiveness of movement and respiratory rate monitoring device in early detection of vital sign deterioration and hospitalisation outcomes among patients admitted at Kitovu Hospital in Central Uganda
REFNo: HS2792ES

To determine the effectiveness of a non-invasive movement and respiratory rate monitoring device in predicting the outcome of medical patients admitted to Kitovu Hospital. To assess the effectiveness of a non-invasive movement and respiratory rate monitoring device in early detection of vital sign deterioration among patients admitted at Kitovu Hospital.
Democratic Republic of Congo 2023-05-18 15:45:26 2026-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JENNIFER WILBURN
ID:
AMR STEWARDSHIP KNOWLEDGE, PERCEPTIONS AND PRACTICES AMONG DISPENSERS IN COMMUNITY DISPENSARY SETTINGS IN KAWEMPE, KAMPALA
REFNo: SS1814ES

1. Evaluate the level of knowledge of antimicrobial resistance and antimicrobial stewardship of individuals working and dispensing antimicrobials within public and private community settings where antibiotics are dispensed.

2. Gain an understanding into perceptions toward AMS of individuals working and dispensing antimicrobials within these settings.

3. Document self-reported practices towards AMS of individuals working and dispensing antimicrobials within these community dispensary settings.
UK 2023-05-18 15:43:17 2026-05-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ali Ssetaala
ID: UNCST-2021-R011817
Multi-site study for Adolescent Girls and Young Women for future HIV vaccines and antibodies candidates for prevention (MAGY).
REFNo: HS2741ES

Aim 1: To investigate factors that influence the design and participation in
clinical trials of future HIV vaccine and bnAb product candidates for AGYW.
Aim 1.1. To understand AGYW, parent/guardians, community members
perspectives on the inclusion of AGYW in future trials to develop and test HIV
vaccine candidates and broadly neutralizing antibodies (bnAb) products.
Aim 1.2. To understand the factors that influence the perceptions (e.g., vaccine
confidence vs hesitancy) of future HIV vaccine and bnAb products among AGYW,
parents/guardians and community members.
Aim 2: Establish AGYW clinical trial preparedness cohorts for the evaluation
of enhanced broadly neutralizing antibodies as a long-acting injectable HIV
prevention product.
Aim 2.1. To establish cohorts of AGYW aged 15-24 years in eastern and southern
Africa using best practices for standard of care, child protection and linkage to
sexual reproductive health (SRH) and HIV services and care.
Aim 2.2. To understand HIV risk and incidence among AGYW aged 15-24 years to
support the calculation of a background HIV incidence counterfactual.
Aim 3: To characterize peripheral immune cells via the least invasive
sampling approaches for assessment or prediction of the suitability of HIV
vaccine candidates for AGYW.
Aim 3.1. To assess the feasibility and acceptability of different sampling techniques
for AGYW
Aim 3.2a. To assess or predict the suitability of HIV vaccine candidates for AGYW
ages 18+ years by characterizing peripheral blood samples and performing
immunological comparison to adults.
Aim 3.2b. To assess or predict the suitability of HIV vaccine candidates for AGYW
ages 15-17 years by characterizing peripheral blood samples and performing
immunological comparison to older adolescents and adults.
Aim 3.3. Examine the temporal relationships between immunological and microbial
factors associated with HIV susceptibility in the female genital tract of AGYW.


Uganda 2023-05-18 15:31:35 2026-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anna Nordén
ID:
Social Acceptance of a green Transition in East Africa
REFNo: SS1666ES

Civil servants and policy makers working with environmental related policies and policy instruments in East Africa.,Enhancing Evironmental related policies and policy instruments in East Africa.,
Sweden 2023-05-18 15:05:28 2026-05-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannington Businge
ID: UNCST-2022-R009477
Board Characteristics, Strategic Orientation and performance of Insurance Companies in Uganda UCUREC-2022-392
REFNo: SS1546ES

To examine the influence of strategic orientation on the relationship between board characteristics and performance of Insurance companies in Uganda.,To determine the influence of board characteristics on performance of Insurance companies in Uganda.,To establish the board practices of Insurance companies in Uganda.,The overall objective of the study will be to determine the influence of strategic orientation on the relationship between board characteristics, and performance of Insurance Companies in Uganda. ,
Uganda 2023-05-18 15:00:59 2026-05-18 Social Science and Humanities Non-Clinical Trial Degree Award
Michael Mukiibi
ID:
Effectiveness of a Smartphone Application on the Accessibility to Information on Maternal, Newborn, and Child Health Care in Slum Settlements in Uganda
REFNo: HS2818ES

i To investigate whether, and how, a smartphone-based job aid used by CHWs improves women’s uptake of facility-based delivery and other maternal health services in Uganda. ii To establish the accessibility of infant and maternal healthcare information by New born and Child health care uptake of facility-based delivery and other maternal health services in Uganda iii To develop a mobile smartphone application to address the accessibility to the information on Maternal, Newborn, And Child Health Care in Slum Settlements in Uganda iv To pilot-test the application in the study area
Uganda 2023-05-11 15:03:31 2026-05-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Maxensia owor
ID: UNCST-2021-R014003
Metabolic Impact of Dolutegravir based ART in Postpartum Women Living with HIV and their Infants” (MI-DART study)
REFNo: HS2809ES

Aim 1: To determine the impact of maternal HIV and DTG-ART on i) energy intake and expenditure, ii) metabolic profile and iii) body composition and weight in postpartum women.
Aim 2: To determine the impact of maternal HIV and DTG-ART on i) energy intake and expenditure, ii) metabolic profile and iii) body composition and growth of their HEU infants.

Uganda 2023-05-11 15:01:13 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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