Winfred Nazziwa
ID: UNCST-2019-R000003
|
Alternative clinical Trial Designs and Methods :The Ethics of Controlled Human Infection studies in Low Resource Settings
REFNo: SS1925ES
The main objective of the study is to examine the ethics, perceptions and acceptability of controlled human infection studies in low resource settings. The specific objectives include;
1. To explore the perceptions of key research stakeholders on the conduct and oversight of controlled human infection studies.
2. To determine general public’s views about acceptability of controlled human infection studies.
3. To explore the experiences of research participants who have participated in a controlled human infection study in Uganda.
|
Uganda |
2023-08-25 8:44:58 |
2026-08-25 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
OLIVIE NAMUJU CAROLYNE
ID:
|
LENGTH OF IN-HOSPITAL STAY, MORTALITY DUE TO HIV-ASSOCIATED CRYPTOCOCCAL MENINGITIS, AND ASSOCIATED FACTORS IN THE ERA OF NEW TREATMENT GUIDELINES AT TERTIARY HEALTH FACILITIES IN UGANDA- A CROSS-SECTIONAL STUDY
REFNo: HS3047ES
Specific Objectives
I. To determine the proportionate contribution of hospitalized patients with HIV-CM on the new guidelines of HIV-CM treatment to all-cause HIV-related mortality.
II. To determine the mean length of hospitalization among HIV-CM after initiation on new guidelines of the HIV-CM treatment regimen at discharge.
III. To determine the factors associated with mortality among the patients on the new guidelines of the HIV-CM treatment regimen
|
Uganda |
2023-08-25 8:27:19 |
2026-08-25 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Joseph Matovu KB
ID: UNCST-2020-R014654
|
Enhancing communication on relationship preservation, safer conception, and pre-exposure prophylaxis (PrEP) to promote HIV testing
REFNo: HS3025ES
Conduct a pilot trial of “PrEPing Healthy Families” with intervention sites implementing the novel communication,Conduct formative research to expand a communication strategy focused on relationship preservation and safer conception into a multi-component intervention with broader reach,To leverage the growing availability of PrEP to determine if and how a communication strategy focused on relationship preservation and safer conception can increase testing and entry into treatment (ART) or prevention (PrEP) among couples in Uganda,
|
Uganda |
2023-08-25 8:26:15 |
2026-08-25 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Christine Muhumuza
ID: UNCST-2023-R008646
|
Uptake, cost-effectiveness, and experiences with HIV testing services among adolescent girls and young women in Greater Rakai, Central, Uganda
REFNo: HS2980ES
i.To assess trends of HTS uptake among adolescent girls and young women (15-24) before and after the targeted testing policy using the Rakai community cohort data from 2013 to 2022.
ii.To identify the factors associated with HTS uptake among adolescent girls and young women in Rakai using the Rakai community cohort data from 2013 to 2022.
iii. To explore experiences and preferences of adolescent girls and young women regarding HTS uptake in greater Rakai
iv. To explore the perceptions of key stakeholders regarding HTS in greater Rakai.
v. To determine the cost-effectiveness of HTS strategies in identifying HIV-positive adolescent girls and young women in greater Rakai.
|
Uganda |
2023-08-25 8:23:39 |
2026-08-25 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Joseph Baluku B
ID: UNCST-2019-R000612
|
The effect of previous active tuberculosis on cardiometabolic profiles of people with HIV at an urban HIV clinic in Uganda
REFNo: HS2991ES
1. To determine the association between previous active TB and each of hypertension, dyslipidemia, elevated FBG, central obesity, and high BMI among PLHIV in Uganda,
2. To compare the frequency of each of hypertension, dyslipidemia, elevated FBG, central obesity, and high BMI among PLHIV with and without previous active TB in Uganda.,
|
Uganda |
2023-08-25 8:21:00 |
2026-08-25 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
James Ajal
ID: UNCST-2023-R008516
|
Network for building resilience and sustainability among smallholder vegetable farmers in East Africa
REFNo: A329ES
Development of capacity for indigenous vegetables research.,Development of IPM packages for sustainability of small-holder vegetable farmers.,Identification of causal agents for key biotic constraints in African indigenous vegetables.,The main research objective is to generate eco-friendly solutions to pest and disease constraints for sustainable production of indigenous vegetables in East Africa,
|
Uganda |
2023-08-25 8:19:01 |
2026-08-25 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Sarah Kiguli
ID: UNCST-2021-R013020
|
SickleInAfrica Protocol for Clinical and Implementation Research in Newborn Screening for Sickle Cell Disease Using Dried Blood Spots for Point of Care Tests.
REFNo: HS2951ES
1. To evaluate the performance characteristics of DBS POCT against IEF/HPLC.
1b. To evaluate the cost of DBS POCT against IEF/HPLC.
2. To determine the knowledge of the availability of POCTs and acceptability of the use of DBS POCT to health-care workers and parents versus standard POCT for screening in Lira Regional Referral Hospital.
3. To determine the cost of DBS POCT for NBS and confirmatory testing using POCT versus conventional NBS and confirmatory testing with IEF/HPLC: i. Apply DBS POCT in NBS versus Early Infant Diagnosis and compare the number of babies identified in each platform who enroll in comprehensive care.
ii. Train study SPARCO Lira Regional Referral Hospital health care workers on the use of DBS for POCT in newborn screening and follow up of babies identified in the programme using standardised guidelines.
iii. Screen 1000 babies in Ghana, Tanzania, Mali, Lira Regional Hospital, Uganda, Zambia and Zimbabwe while -Nigeria which has 25 subsites will screen 2,500 babies using DBS POCT and enter the identified babies into REDCap using SPARCO CRF.
` iv. Assess the implementation outcomes using CFIR
a. Assess the adoption of DBS for NBS using the three technologies POCT, IEF, HPLC among providers (i.e. midwives, physicians, nurses, councillors) in Lira Regional Referral Hospital.
b. Evaluate the appropriateness of the 3 technologies implemented at Lira Regional Referral Hospital across implementing sites and assess the barriers and facilitators guided by CFIR, inner and outer settings.
c. Assess the technology and implementation costs and sustainability of the three technologies in the various healthcare centres among the six countries.
|
Uganda |
2023-08-25 8:13:57 |
2026-08-25 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Mark Kaddumukasa
ID: UNCST-2020-R001798
|
SELF MANAGEMENT INTERVENTION FOR REDUCING EPILEPSY BURDEN AMONG UGANDANS WITH EPILEPSY
REFNo: HS2944ES
1. To assess the efficacy of SMART- U vs. eTAU via an RCT.
H1: Individuals randomized to SMART-U will have significantly improved QOL and fewer seizures compared to eTAU.
H2: Individuals randomized to SMART-U will have greater improvement in depression and functional status compared to eTAU.
2. To use short message service (SMS) delivered via mobile phone text to validate patient self-reported seizure occurrence and push epilepsy self-management messaging in a practical/accessible format.
3. To obtain input from stakeholders (patients, family and clinicians) guided by an Integrated Promotion Action on Research Implementation in Health Services (i-PARIHS) framework to help establish sustainable infrastructure that will facilitate future scale up of SMART in Uganda with epilepsy partners
|
Uganda |
2023-08-25 8:11:10 |
2026-08-25 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Sharon Pang Sze Lu
ID:
|
Transform Randomised Controlled Trial in Uganda
REFNo: SS1823ES
To evaluate the impact of the Transform program on the key indicators in values, health and livelihood in Uganda
|
Hong Kong |
2023-08-25 8:07:30 |
2026-08-25 |
Social Science and Humanities |
Clinical Trial |
Non-degree Award |
|
Sulaiman Bbosa
ID:
|
MONITORING AND EVALUATION SYSTEMS AND PERFORMANCE OF HUMANITARIAN ORGANIZATIONS IN UGANDA: A CASE OF UGANDA RED CROSS SOCIETY IN EASTERN REGION
REFNo: SS1251ES
To examine how data quality influences the performance of monitoring and evaluation systems of Uganda Red Cross Society in Eastern Uganda,To analyse how structure of monitoring and evaluation influences the performance of Uganda Red Cross Society in Eastern Uganda,To assess how human resource capacity influences the performance of Uganda Red Cross Society in Eastern Uganda,To establish how the Monitoring and evaluation methods influences the performance of Uganda Red Cross Society in Eastern Uganda,The purpose of the study is to examine the contribution of the monitoring and evaluation systems and the performance of humanitarian organizations,
|
Uganda |
2023-08-25 8:05:14 |
2026-08-25 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
APON ISMENE LINDA
ID:
|
CASH MANAGEMENT, SELF-ORGANIZATION, INTERNAL AUDITING AND SUSTAINABILITY OF SMALL AND MEDIUM ENTERPRISES IN UGANDA
REFNo: SS1658ES
1. The study intends to examine the nature of sustainability of small and medium enterprises (SMEs) in Northern Uganda.
2. To examine the relationship between cash management and sustainability of small and medium enterprises
3. To examine the relationship between cash management and internal auditing of small and medium enterprises
4. To examine the relationship between internal auditing and sustainability of small and medium enterprises
5. To examine the relationship between cash management and self-organisation of small and medium enterprises
6. To examine the relationship between self-organisation and sustainability of small and medium enterprises
7. To examine the mediating role of internal auditing on the relationship between cash management and sustainability
8. To examine the mediating role of self-organisation on the relationship between cash management and sustainability
|
Uganda |
2023-08-25 8:03:10 |
2026-08-25 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
.jpg)
|
Fabien Schultz
ID: UNCST-2023-R008622
|
Between Emerald Worlds: Analyzing the Spiritual, Ritual, and Pharmacological Facets of Neuroactive Natural Materials in Rural Uganda
REFNo: SS1894ES
Research questions to be addressed by this project: 1) How do various indigenous communities in Uganda understand, use, and prepare neuroactive plants, fungi, and other natural materials for spiritual, ritual, and ceremonial purposes and within their healthcare systems; 2) can the pharmacological targets of these materials be identified, and what active ingredients are causing the claimed effects; 3) can animal self-medication evidence for the use of neuroactive materials by the apes be generated for the first time; and 4)how to develop and to distinguish best-practice models for the implementation of the Nagoya Protocol for both non-financial and financial benefit-sharing when the intellectual property holders are either a) members of local human populations or b) apes (an unprecedented case)?
Main objective: To help fill gaps in social and natural scientific research on neuroactive natural remedies in a region of the world about which very few ethnopharmacological studies on the use of neuroactive natural remedies exist.
Specific objectives: 1) The first-time documentation of the cultural, spiritual, and ritual use of neuroactive natural remedies in rural Uganda, including methods of preparation and administration in a cultural, potentially ceremonial, setting; 2) the identification of new bioactive substance leads on the basis of the archiving of the chemical biodiversity of the collected samples; 3) the generation of new knowledge on how different populations interpret the spiritual/ritual settings of various neuroactive natural materials; 4) the contribution of new insights into the benefits of neuroactive natural remedies with respect to mental health and societal well-being; 5) a deeper understanding of the importance/intentions of various neuroactive substances for spiritual and ritual purposes within cultural worldviews; 6) the investigation of potential overlap in the use of neuroactives between humans and non-human primates at the study sites; 7) the shifting of negative Western views on neuroactive substances as stimulants/sedatives and rightfully DEA Schedule I substances.
|
Germany |
2023-08-18 9:46:36 |
2026-08-18 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
REBECCA NANTANDA
ID: UNCST-2019-R001533
|
Assessment of feasibility, acceptability, hesitancy, safety, effectiveness and immunogenicity of COVID-19 vaccines among children in Uganda
REFNo: HS2910ES
1. To assess the feasibility and acceptability of COVID-19 vaccination of children in Uganda.
2. a) To determine the prevalence of hesitancy to COVID-19 vaccination for children in
Uganda.
b) To describe the drivers of hesitancy for vaccination of children against COVID-19 in
Uganda.
3. To assess the safety of COVID-19 vaccines among children aged 12-17 years in Uganda.
4. To determine immunogenicity the BioNTecg/Pfizer of among children aged 12-17 years in Uganda.
5. To determine the effectiveness of COVID-19 vaccines among children aged 12-17 years in Uganda.
|
Uganda |
2023-08-18 9:40:38 |
2026-08-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Adoke Yeka
ID: UNCST-2021-R004300
|
A pilot study evaluating the feasibility, acceptability and impact of use of highly sensitive malaria RDTs (NxTek™) vs ordinary malaria RDTs on malaria incidence in Uganda: a cluster-randomised trial
REFNo: HS2988ES
1. To determine the impact of detecting and treating additional malaria cases on malaria morbidity, 2 years following introduction of HS-RDTs for diagnosis of malaria in Uganda.
2. To assess feasibility of use (ease of test interpretation, delivery, restocking, storage, invalid tests, and reporting rates) of HS-RDTs among implementers in Uganda.
3. To compare clinical care outcomes for malaria cases diagnosed with HS-RDTs and cRDTs in Uganda.
4. To estimate the cost-effectiveness of delivering HS-RDTs, as compared to cRDTs.
|
Uganda |
2023-08-18 9:13:55 |
2026-08-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Adoke Yeka
ID: UNCST-2021-R004300
|
An adaptive, randomized, active-controlled, open-label, sequential cohort,
multicenter study to evaluate the efficacy, safety, tolerability and
pharmacokinetics of intravenous cipargamin (KAE609) in adult and pediatric
participants with severe Plasmodium falciparum malaria (KARISMA –
KAE609’s Role In Severe Malaria)
REFNo: HS1980ES
Primary objective
To assess the efficacy of different doses of
intravenous cipargamin vs artesunate by evaluating the proportion of
participants with ? 90% reduction of parasitemia at 12 hours post
administration of the first dose.
Secondary Objectives
1. To assess the presence/absence of severe malaria related individual
signs over time
2. To evaluate parasite clearance dynamics and proportion of participants
with recrudescence and reinfection
3. To assess recovery of participants as measured by time (days and hours)
to discharge from hospital or recovery from prostration
4. To evaluate the safety and tolerability of IV cipargamin
5. To assess the risk of long term neurological sequelae for participants at
Day 29
6. The assess the risk of hemolysis (early and delayed) during the study
duration
7. To characterize the plasma pharmacokinetics of IV cipargamin
|
Uganda |
2023-08-18 9:05:14 |
2026-08-18 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Juliane Etima
ID: UNCST-2022-R008983
|
Young Generation Alive Survey: Determining Knowledge, Aspirations, and Behaviors of Ugandan Adolescents and Young People Living with HIV.
REFNo: SS1910ES
To understand the HIV knowledge and behaviors among HIV+ and perinatally exposed adolescents and young people in Uganda with respect to achieving career aspirations, financial security, and safe intimate relationships.,
|
Uganda |
2023-08-15 15:43:39 |
2026-08-15 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Fiona Ssozi Catherine
ID:
|
PATHWAYS TO CHANGE: TOWARDS GENDER JUSTICE IN SCIENCE, ENGINEERING, TECHNOLOGY AND MATHEMATICS (STEM) RESEARCH IN AFRICA (GEJUSTA)
REFNo: SIR240ES
Primary objective: Examine causes of under-representation and reframe Gender Analysis in STEM in Africa
Secondary objectives: Map under-representation, barriers and support mechanisms; explore STEA+M approaches; Develop Gender-aware design methodologies; Develop a support network for mentoring early-career female researchers
|
Uganda |
2023-08-15 15:42:06 |
2026-08-15 |
Engineering and Technology |
Non-Clinical Trial |
Non-degree Award |
|
Jesca Nantume
ID: UNCST-2021-R013984
|
EVALUATING EQUITABLE ACCESS TO HEALTH SERVICES FOR SCHISTOSOMIASIS IN COMMUNITY-BASED HEALTH CENTERS; A MIXED METHODS CROSSECTIONAL STUDY IN MAYUGE AND KALUNGU DISTRICT IN UGANDA
REFNo: SS1887ES
3. To identify and understand the barriers that hinder equitable access to health services for schistosomiasis, including socio-economic factors such as income, education level, and employment status, as well as cultural beliefs, attitudes, and practices that affect healthcare-seeking behaviors.,2. To evaluate the accessibility of health services for schistosomiasis in terms of geographical proximity, transportation, cost, and waiting times for individuals seeking diagnosis, treatment, and follow-up care.,1. To assess the availability of health services for schistosomiasis in community-based health centers in Mayuge and Kalungu Districts, Uganda, including the availability of diagnostic tools, treatment options, and healthcare professionals trained in schistosomiasis management.,The main aim of the study is to assess and evaluate the level of equitable access to health services for schistosomiasis in community-based health centers in Mayuge and Kalungu Districts, Uganda, by considering various factors such as availability, accessibility, utilization, and quality of services. The objective is to gain a comprehensive understanding of the barriers and facilitators that impact equitable access to schistosomiasis healthcare services, including the influence of socio-economic factors, cultural beliefs, knowledge and awareness levels, and gender dynamics.,
|
Uganda |
2023-08-15 15:40:28 |
2026-08-15 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Alison Elliott
ID: UNCST-2023-R006524
|
Understanding the role of, and relationship between, structural, social and biological determinants of vaccine response to improve vaccine impact in Kenya and Uganda: a formative study.
REFNo: HS2901ES
1. To conduct a scoping review exploring how social, structural and biological drivers interact to influence vaccine response.
2. To undertake formative ethnographic case studies to investigate these interactions in two communities where biological factors are known to influence vaccine response.
3. To map stakeholders and influencers critical to vaccine impact in Uganda and Kenya.
4. To work with stakeholders and communities to co-design the VAnguard community surveys to be conducted in year 2 of the programme
|
UK |
2023-08-10 15:46:52 |
2026-08-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Sylivia Namwano
ID: UNCST-2023-R008071
|
A pragmatic early detection and warning model for reduction of landslide effects for communities at risk
REFNo: SIR243ES
To evaluate the efficiency, reliability, effectiveness and usability of the designed pragmatic early detection and warning model for reduction of landslide effects for communities at risk,To establish ideal characteristic of an effective and efficient landslide early detection and warning systems for communities at risk,To design a pragmatic early detection and warning model for reduction of landslide effects for communities at risk,
|
Uganda |
2023-08-10 15:22:18 |
2026-08-10 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
|
| View |
|
Sort By: |
|
|
|
| |
|