Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Bruce Kirenga J
ID: UNCST-2019-R001460
A Prospective, Clinical Trial Examining the Immune Response of Participants Receiving Modified Vaccinia Ankara (MVA) Vaccine in Africa,”-Mpox Vax Africa
REFNo: HS5575ES

To determine:

the development of MVA-BN-specific antibodies at week 6 post-first vaccination with MVA-BN in
a population recruited in Africa, and compare to a population recruited in Europe.

Durability of MVA-BN-specific antibodies at week 24 post-first vaccination with MVA-BN.
● Factors associated with MVA-BN-specific antibody responses at week 48 post-first
vaccination with MVA-BN.
● Durability of MVA-BN-specific antibodies at week 48 post-first vaccination between a
population recruited in Africa and a population recruited in Europe.
● Durability of MVA-BN-specific antibodies at week 48 post-first vaccination with MVA-BN in
understudied populations (women and PLWH).
● Prevalence of asymptomatic seroconversion to mpox by week 48 post-first vaccination
Uganda 2025-02-08 13:35:10 2028-02-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
THE SECOND UGANDA TB PREVALENCE SURVEY (TBPS2)
REFNo: HS5269ES

Estimating the sizes of key and vulnerable TB populations as defined in the national gender and key and vulnerable populations assessment report nationally and sub nationally,Evaluating factors associated with TB including HIV, diabetes, undernutrition, tobacco smoking, alcohol ab use, and socio-economic status,,Updating population-based estimates of TB burden using results from the prevalence survey ,Assessing healthcare-seeking behaviors and understand where individuals with TB symptoms seek medical care,The secondary objectives of TBPS2 in Uganda encompass: The prevalence of symptoms suggestive of pulmonary tuberculosis (PTB) and determining radiological abnormalities among individuals aged ≥15 years, ,The primary objective is to determine the national and subnational prevalence of bacteriologically confirmed pulmonary TB among the general population aged ≥15 years,The goal of the survey is to enable the country (MOH/NTLP and partners) to gain a better understanding of the current burden of TB, health-seeking behavior and health system response in order to identify ways of improving TB programming towards ending TB in the country.,
Uganda 2025-02-07 18:27:07 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DANIEL KIIZA
ID: UNCST-2024-R004044
Retrospective chart review of patients with Laboratory-Confirmed Sudan Virus Disease Hospitalized in Two Ebola Disease Treatment Units in Uganda (September 2022 to January 2023)
REFNo: HS5541ES

To evaluate the safety and clinical course of patients receiving investigational treatments for SVD,To identify host and disease factors associated with outcomes from SVD,To characterize the natural history and outcomes of Sudan virus disease (SVD) among hospitalized patients with RT-PCR detected Orthoebolavirus sudanense (SUDV) RNA,
Uganda 2025-02-07 18:10:59 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
AN OUTCOME RESEARCH ON THE WESTERN UGANDA BANTWANA PROGRAM ON VIOLENCE AGAINST CHILDREN IN SCHOOLS AND SURROUNDING COMMUNITIES (VACiSC) IN THE THREE DISTRICTS OF KABAROLE, KYENJOJO and BUNYANGABU
REFNo: SS3625ES

The study aims to assess the effectiveness of the Western Uganda Bantwana Program (WUBP) in preventing and responding to Violence Against Children (VAC), including child sexual abuse (CSA), in schools and surrounding communities in the three Districts of Kabarole, Kyenjojo, and Bunyangabu

Specific Objectives
1. To measure the change in knowledge, attitude and practices on risks exposures to VACiSC including CSA with focus on prevention and response among children, young adults, caregivers and teachers.
2. To assess how the WUBP aligned to the needs of communities and existing practices (structures and approaches) on prevention and response to VACiSC including CSA.
3. To evaluate the role of caregivers, teachers, para-social workers, and community leaders in creating and maintaining safe environments for children.

Uganda 2025-02-07 18:09:14 2028-02-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eva Smallegange Sophia
ID: UNCST-2023-R005788
Effectiveness of PlayMatters in Uganda: a teacher professional development programme aiming to integrate Learning through Play as pedagogical approach in the classroom
REFNo: SS3617ES

1. To study the effectiveness of PlayMatters Teacher professional Development program on teacher practices and teacher wellbeing.
2. To study how do the effects of the intervention vary by teachers’ age, gender, displacement status, level of education and professional experience?
3. To study how do effects of the intervention vary by differences in adherence to implementation of the Teacher Continuous Professional Development (TCPD) component of the intervention?
4. To study the effectiveness of the PlayMatters Teacher professional Development program at child outcome level (cognitive, social, emotional, physical and creative skills and on their mental health and wellbeing).
5.To study the cost-effectiveness of the PlayMatters intervention.
Netherlands 2025-02-07 18:07:38 2028-02-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
Evaluation of the One Acre Fund project - making 34,000 coffee farmers more resilient by 2027
REFNo: A560ES

To establish whether all household members are equally benefiting from the impacts of the project and how? ,To determine which pursued pathways of change are the main drivers in delivering outcome and impact? ,To establish the causal effects of the project for direct project participants? ,
Uganda 2025-02-07 18:04:15 2028-02-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Michelle Brown
ID: UNCST-2022-R009670
Describing the vocal repertoire of L’Hoest’s monkeys
REFNo: NS410ES

To test whether L’Hoest’s monkeys (Allochrocebus lhoesti) contradict the ‘social complexity hypothesis’ by determining whether they communicate in frequencies too low for human hearing.
USA 2025-02-07 18:02:59 2028-02-07 Natural Sciences Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
Incidence and economic impacts of bovine mastitis in smallholder dairy farms in Kenya and Uganda
REFNo: A564ES

To assess knowledge of bovine mastitis, its control and treatment among smallholder dairy farmers.
To assess the effectiveness of using cell phone technology as a method of disseminating information on udder health to farmers.
To estimate the incidence rate of clinical and subclinical mastitis among recently-calved dairy cows (≤4 weeks prior to baseline data collection).
To determine the drivers of bovine mastitis among sampled dairy cows.
To estimate the monthly and annual financial losses attributed to clinical and subclinical mastitis.
Uganda 2025-02-07 18:01:56 2028-02-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
Assessment of the functionality of health unit management committees in primary healthcare health facilities in Uganda: a case of health center IIIs
REFNo: HS5407ES

a) To determine the presence and functionality of HUMCs in HCIIIs
b) To determine the factors influencing the functionality status of HUMCs in HCIIIs
c) To identify any interventions needed to strengthen the performance of HUMCs in HCIIIs.

Uganda 2025-02-07 17:59:08 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
Factors influencing the Functionality of Medicines and Therapeutic Committees in Public Health Facilities in Uganda: A Longitudinal Assessment
REFNo: HS5391ES

a) Provide the current functionality of MTCs in public HFs
b) Determine the factors associated with the functionality of MTCs in public HFs

Uganda 2025-02-07 17:56:57 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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