Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Constance Buzaare
ID: UNCST-2024-R005359
 Project-Based Learning, Conventional Teaching Approaches and Developing English Language Proficiency among Refugee Learners: A case of Bidi-Bidi refugee settlement
REFNo: SS3988ES

i. To assess the English language proficiency of refugee learners before implementing project-based learning and traditional learning approaches in the Bidi Bidi refugee settlement. ii. To examine the level of English language proficiency of refugee learners after the interventions of project-based learning and traditional learning approaches in Bidi Bidi settlement. iii. To determine the difference in English language proficiency among refugee learners before and after implementing project-based learning, compared to traditional teaching approaches in Bidi Bidi settlement. iv. To assess learners' perceptions of project-based and traditional learning approaches in enhancing English language proficiency among refugee learners in Bid Bidi Settlement.
Uganda 2025-07-09 17:06:10 2028-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Edwin Kigozi
ID: UNCST-2021-R013215
 Exploring the Potential of Graduate Nurses in Uganda to Advance Planetary Health and Foster Climate-Resilient Healthcare Systems.
REFNo: HS6116ES

Main aim.
This study aims to explore the barriers and facilitators for graduate nurses in promoting climate-resilient healthcare systems.

Specific Objectives:
1. To examine how graduate nurses in Uganda are involved in promoting climate-resilient healthcare systems within Uganda’s health sector.
2. To explore how education, training, current roles and work conditions influence the capacity of graduate nurses to engage in climate-resilient healthcare advocacy within and beyond traditional clinical settings.
3. To explore additional needs to support graduate nurses in Uganda to contribute to climate-resilient healthcare systems.

 Uganda 2025-07-09 16:21:41 2028-07-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Esther Cathlyn  Atukunda
ID: UNCST-2022-R009265
 Evaluating Healthy Families PrEP: an intervention to promote PrEP use during periconception, pregnancy and postpartum periods for women in rural Uganda
REFNo: HS6117ES

1. Adapt Healthy Families-PrEP (HF-PrEP) to community clinics in Mbarara and Sheema Districts, Uganda to include postpartum women guided by our conceptual framework and the Consolidated Framework for Implementation Research (CFIR

2. Test Healthy Families-PrEP intervention effectiveness in a cluster-randomized control trial in Ugandan community health centers (HCs)

3. Determine incremental cost-per-person participating in Healthy Families-PrEP and estimate cost-effectiveness per incident HIV infection averted among women and their infants.
 Uganda 2025-07-09 16:14:46 2028-07-09 Medical and Health Sciences Clinical Trial Non-degree Award
LOIS BAYIGGA
ID: UNCST-2024-R004310
 IN VIVO GENE THERAPY: AN HIV CURE IN A SYRINGE
REFNo: HS6079ES

To evaluate the efficacy of the CRISPR/Cas dual guide RNA in curing HIV infection in a humanized immune system,To engineer lipid nanoparticles with receptors for targeting specific cells and tissues,To test the efficacy of CRISPR/Cas in reducing the HIV reservoir in infected cells and tissues from both adult and pediatric populations infected with different HIV subtypes,To evaluate the effectiveness of CRISPR/Cas dual guide RNA in reducing the HIV reservoir and curing HIV infection,
 Uganda 2025-07-08 13:58:37 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ssemanda Ronald
ID: UNCST-2025-R019141
 Tax Type Dynamics, Filler's Perceptions, and Filing Compliance: An Empirical Study of Uganda's Public Sector
REFNo: SS4032ES

To thoroughly examine tax filing compliance in Uganda's public sector, this study will aim to achieve the following Specific Objectives:
1. To examine the effect of Income Tax on filing compliance within Uganda’s public sector.
2. To assess the effect of Value Added Tax (VAT) on filing compliance within Uganda’s public sector.
3. To analyze the effect of Pay-As-You-Earn (PAYE) on filing compliance within Uganda’s public sector.
4. To evaluate the effect of Withholding Tax (WHT) on filing compliance within Uganda’s public sector.
5. To develop a model to enhance tax compliance in public organizations by addressing tax filers' perceptions across various tax types.
 Uganda 2025-07-08 11:24:40 2028-07-08 Social Science and Humanities Non-Clinical Trial Degree Award
Ivan Segawa
ID: UNCST-2021-R012795
 Optimizing Community-Pharmacy PrEP Delivery for Cisgender Female Sex Workers in Uganda
REFNo: HS6178ES

Aim 1: Compare the potential reach and accessibility of PrEP services through community retail pharmacies and PrEP facilities in Kampala. Aim 2: Evaluate pharmacy capacity and staff perspectives on delivering PrEP through community retail pharmacies in Kampala.
Uganda 2025-07-08 11:22:09 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
 Assessment of Pharmacovigilance Systems, Knowledge and Reporting in public health facilities. A Cross-sectional Assessment
REFNo: HS6195ES

i) To evaluate functionality of PV systems in public health facilities in Uganda. ii) To evaluate current PV knowledge at public health facilities in Uganda. iii) To establish evaluate the current pharmacovigilance reporting rates in public health facilities in Uganda. iv) To establish the factors influencing pharmacovigilance knowledge among health facilities practitioners in public health facilities in Uganda. v) To establish the factors influencing the reporting rates of ADRs/AEFI in public health facilities in Uganda.
Uganda 2025-07-08 11:17:16 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
 Antimicrobial Use Surveillance in Public Hospitals in Uganda: A Retrospective Cross-sectional Assessment
REFNo: HS6197ES

a) To assess the compliance to treatment guidelines in antimicrobial use in outpatient departments in public hospitals in Uganda b) To assess the compliance to treatment guidelines in antimicrobial use in inpatient departments in public hospitals in Uganda c) To assess the current performance of antimicrobial prescribing indicators in outpatient departments in public hospitals in Uganda d) To assess the current performance of antimicrobial prescribing indicators in inpatient departments in public hospitals in Uganda.
Uganda 2025-07-08 11:15:06 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Pebalo Pebolo
ID: UNCST-2022-R010630
 Towards understanding maternal health for youth with Disabilities in Uganda
REFNo: HS6070ES

To explore experiences and perceptions of healthcare providers regarding the provision of maternal healthcare services to Female Youth with Disabilities in Uganda.,To document the perspectives of Female Youth with Disabilities regarding their experiences of accessing maternal healthcare services in Uganda.,To explore the lived experiences of pregnancy and childbirth among Female Youth with Disabilities in Uganda.,To synthesize evidence on access to maternal healthcare services for Female Youth with Disabilities in Sub-Saharan Africa.,This study seeks to understand the maternal health for FYWD based on their own experiences and perceptions and those of the maternal healthcare providers in Uganda. The knowledge and insight generated will contribute to improving the maternal health and healthcare services for WWD particularly FYWD in Uganda and other low- and middle-income countries,
 Uganda 2025-07-08 11:12:51 2028-07-08 Medical and Health Sciences Non-Clinical Trial Degree Award
EGIRU EREGU EMMA ISAIAH
ID: UNCST-2021-R012653
 PREVALENCE, RISK FACTORS AND OUTCOMES OF LOW BIRTH WEIGHTS AMONG NEONATES; A RETROSPECTIVE STUDY AT KAYUNGA REGIONAL REFERRAL HOSPITAL
REFNo: HS6137ES

Prevalence of low birth weight among the admissions in the neonatal unit What are the risk factors for low birth weight in kayunga What are the outcomes of admitted low birth weight
 Uganda 2025-07-08 11:10:17 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ian Munabi
ID: UNCST-2023-R007147
 EVALUATION OF THE MASTER OF SCIENCE IN BIOETHICS PROGRAM IMPLEMENTATION FROM 2015 -2024
REFNo: HS6089ES

ii. To review and document the outputs and implementation of the Master of Science in Bioethics curriculum at MakCHS over the last ten years. ,i. To examine stakeholder perspectives on the Master of Health Science in Bioethics program’s implementation. ,
 Uganda 2025-07-08 11:05:32 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Baptist Asiimwe
ID: UNCST-2021-R013716
 Factors influencing the quality of nursing care (QNC) among nurses and their patients’ perspectives in tertiary hospitals in Uganda: A mixed method study.
REFNo: HS6072ES

1) Determine the nurses' perceived level of QNC in tertiary hospitals in Uganda.
2) Establish the factors associated with nurse-perceived levels of QNC in tertiary hospitals in Uganda.
3) Determine the patients’ level of satisfaction with QNC and associated factors in tertiary in Uganda.
4) To explore the patient’s and nurses’ perceptions of nursing care received from tertiary hospitals in Uganda.

Uganda 2025-07-08 11:00:32 2028-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hosea Kiprotich
ID: UNCST-2024-R002048
 DEVELOPMENT OF AN IN-HOUSE PROTOCOL FOR MEASUREMENT OF HEMOGLOBIN FROM DRIED BLOOD SPOTS
REFNo: NS944ES


GENERAL OBJECTIVE

To establish a method for the measurement of haemoglobin from DBS.

SPECIFIC OBJECTIVES

1. To develop and optimize a protocol for measurement of Hb from dried blood spots.
2. To evaluate assay performance for hemoglobin measured in DBS eluate: inter and intra- assay variation, linearity, lower limit of detection and accuracy.
3. To determine the effect of storage temperature, time, and humidity on the performance characteristics of Hb measurement using DBS

 Uganda 2025-07-08 10:47:58 2028-07-08 Natural Sciences Non-Clinical Trial Degree Award
Paul Edabu
ID: UNCST-2025-R016842
 Socio-ecological factors and mental health of refugee children aged 10 to 17 years in Imvepi settlement-Terego District, West Nile region
REFNo: SS3792ES

1. To examine the prevalence of mental health issues among refugee children in West Nile region.
2. To explore the socio-ecological risk factors contributing to mental health issues in refugee children in West Nile region.
3. To investigate the protective factors and coping mechanisms that support the mental health of refugee children in West Nile region.
4. To establish the effectiveness of current community and systemic interventions to support the mental health of refugee children in West Nile region

 Uganda 2025-07-08 10:36:02 2028-07-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Use of Remnant Clinical Samples from Health Facilities for Micronutrient Surveillance in Uganda
REFNo: HS6218ES

3.Determine the prevalence micronutrient deficiency using remnant clinical samples ,2. Analyze remnant clinical samples for micronutrient and inflammatory biomarkers using a multiplex assay,1.Establish a mechanism for acquisition, storage and transportation of remnant clinical samples from health facilities ,
 Uganda 2025-07-07 13:37:02 2028-07-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Lubanga
ID: UNCST-2025-R018596
 Displacement, Mental Health, and Access to Care: Understanding Women Refugee’s Well-being in Urban Uganda
REFNo: SS3943ES


Investigate the primary mental health and psychosocial support challenges faced by refugee women in Kampala.

Examine the structural barriers (e.g., documentation requirements, bureaucratic delays, geographic access) that hinder mental health care access.

Identify facilitators and resilience factors that support mental well-being and access to mental health and psychosocial support services.
Uganda 2025-07-04 15:20:27 2028-07-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aidah Nanvuma
ID: UNCST-2024-R015734
 Assessing Health Care Providers Knowledge, Attitudes, and Practices on Sexually Transmitted Infections Post Exposure Prophylaxis in Urban Clinics in Kampala, Uganda.
REFNo: HS6083ES

1. Assess knowledge of STI PEP among HCPs in urban health facilities in Uganda. 2. Evaluate attitudes towards STI PEP among HCP in urban health facilities in Uganda. 3. Characterise current practices related to STI PEP among HCP in urban health facilities in Uganda.
Uganda 2025-07-04 14:27:02 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julius Kizito
ID: UNCST-2025-R017731
 From shadows to spotlight: Behavioral observation of East African pottos (Perodicticus ibeanus) in Kibale National Park, community knowledge and awareness about pottos.
REFNo: NS950ES

To investigate the behavioral repertoire, and substrate use, of pottos in Kibale National Park and adjacent villages, assess community knowledge and awareness of people living near the park about pottos, and conduct conservation education
Uganda 2025-07-04 14:18:55 2028-07-04 Natural Sciences Non-Clinical Trial Non-degree Award
Salim Kombo
ID: UNCST-2023-R005870
 OPTIMIZING STRATEGIES FOR PROSOCIAL BEHAVIOR IN UGANDA - A SOCIAL NETWORK STUDY
REFNo: SS4005ES

Descriptive Social Network Study: Assess the relationship between network structure and pro-social engagement, focusing on network density, centrality, homophily, and bridging ties. Qualitative Study: Investigate the dissemination of pro-social engagement information, identifying effective channels, key information injectors, motivators, barriers, and incentives for increasing engagement.,Descriptive Social Network Study: Network Structure and Engagement Correlation: Assess the density and structure of social networks and correlate them with pro-social engagement levels. Centrality and Motivational Influences: Identify the centrality of highly engaged and committed individuals and key motivators within the networks. Homophily and Bridging Ties: Analyze the extent of homophily in pro-social engagement profiles and identify key individuals who bridge different engagement levels. Qualitative Study: Information Dissemination and Effective Channels: Investigate how community monitors disseminate pro-social engagement information and identify the most effective forums and platforms. Optimal Information Injectors and Motivators: Determine the best individuals for injecting and motivating pro-social engagement and their effective qualities. Barriers and Incentives for Engagement: Explore barriers to engagement and identify incentives or changes to increase engagement among less-engaged individuals.,Descriptive Social Network Study: Assess the relationship between network structure and pro-social engagement, focusing on network density, centrality, homophily, and bridging ties. Qualitative Study: Investigate the dissemination of pro-social engagement information, identifying effective channels, key information injectors, motivators, barriers, and incentives for increasing engagement.,
 Kenya 2025-07-04 14:15:43 2028-07-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Laura Nsangi Joan
ID: UNCST-2025-R016715
 ValgaNciclovIR for CMV Viraemia in AdvaNced HIV diseAse
REFNo: HS6040ES

The primary objective is to determine if valganciclovir is safe and efficacious in reducing CMV viraemia amongst hospitalised adults with advanced HIV disease and CMV viraemia.
Secondary objectives are to determine the effect of valganciclovir on mortality, to study its pharmacokinetics and explore the immunological response of patients with CMV viraemia before and after treatment with valganciclovir.

 Uganda 2025-07-04 14:08:02 2028-07-04 Medical and Health Sciences Clinical Trial Non-degree Award
Luiza CardosodeAndrade
ID: UNCST-2025-R018410
 Measuring chlorination in areas with active Evidence Action chlorine delivery interventions
REFNo: SS3948ES

This study aims to assess the take-up of drinking water chlorination under DSW and ILC in Uganda and to compare different measurement methodologies to help improve monitoring protocols. The primary outcome of interest is the total number of people who use water pointers with DSW or ILC for which we can detect chlorine residual in the drinking water. Secondary outcomes explore differences in the methods used to estimate chlorination. In particular, we are interested in comparing chlorination rates measured using two different sampling frames (self-reported water point users and water point users listed) and two different chlorine residual measurement instruments (color discs and colorimeters). The tertiary outcome is the functionality of chlorination devices, which may be connected to low adoption. Finally, additional data will be collected to perform an exploratory analysis on other factors that may influence the adoption of chlorine for water treatment, such as the distance to the nearest water point where chlorine is available and the occurrence of symptoms related to the consumption of contaminated water.
 Brazil 2025-07-04 14:02:44 2028-07-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
 Maternal Ultrasound Prospective Observational Study for Machine Leaning Model Training
REFNo: HS6020ES

1. Collect ultrasound data from pregnant and non-pregnant individuals presenting at Kawempe national referral hospital. 2. Use the collected data and ultrasound images to train and validate MOBUS algorithms.,
 Uganda 2025-07-04 14:00:42 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID: UNCST-2021-R011663
 SEROPREVALENCE OF MARBURG VIRUS INFECTION AND OTHER WHO-PRIORITY PATHOGEN IN THREE (3) COUNTRIES IN AFRICA
REFNo: HS6241ES

Primary objectives 1.To assess previous exposure to Marburg Virus (MARV) Infection in the general population in three (3) African countries, determined by measuring circulating IgG antibodies.
2.To estimate MARV force of infection (FOI) in the three (3) African countries. 3.To develop a platform for the implementation of seroprevalence of WHO priority pathogens in Africa Secondary objectives 1.
To characterize age-specific and gender-specific seroprevalence trends. 2.To determine risk factors associated with prior infection with MARV in the three (3) African countries. 3. To assess host genetic factors including single nucleotide polymorphism (SNP) of candidate genes that could be associated with susceptibility/protection from infection with MARV and other outbreak-worthy pathogens. 4.To estimate the seroprevalence of other WHO priority filovirus pathogens, including EBOV, SUDV, BDBV, TAFV, RAVN, etc. Exploratory objectives 1.To evaluate potential cross-reactivity of MARV IgG with other filoviruses. 2.To investigate neutralizing capacity of human monoclonal antibodies against MARV
Uganda 2025-07-04 13:58:59 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ERIC WOBUDEYA
ID: UNCST-2019-R001047
 Paediatric Post-TB home-based Pulmonary Rehabilitation Feasibility Study
REFNo: HS6222ES

Primary objective:
• To explore the feasibility of implementing a 6-week at home pulmonary rehabilitation program in children with diagnosed with PTLD, including measures of participant retention and adherence.

Secondary objectives:
• To evaluate the change in health-related quality of life following the pulmonary rehabilitation intervention.
• To assess the change in exercise capacity following the 6-week pulmonary rehabilitation intervention.
• To explore the experiences and perceptions of children, caregivers, and healthcare providers related to the acceptability and feasibility of the pulmonary rehabilitation program

 Uganda 2025-07-04 13:57:06 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tarekegn Abeku Abose
ID: UNCST-2023-R005864
 improving early warning and control of mosquito-borne disease outbreaks caused by extreme weather in Uganda
REFNo: HS5162ES

Main Objective
1. The project’s main objective is to strengthen the health system capacity in Uganda for improved early warning and rapid control of mosquito-borne disease outbreaks caused by extreme weather events, focussing on malaria RVF and YF.
Specific Objectives
1. 1. To document past mosquito-borne disease outbreaks in Uganda and analyse their association with extreme weather
2. 2. To develop and validate a risk index and early warning models to forecast the outbreaks
3. 3. To develop a platform that maps risks and generates predictions continuously, where real-time surveillance data feed into, for routine use by disease control programmes
4. 4. To develop an outbreak preparedness and response plan for various risk scenarios
5. 5. To facilitate adoption and use of the system
6. 6. To engage communities in the research activities
 UK 2025-07-04 13:55:42 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Kiweewa
ID: UNCST-2020-R014929
 Longitudinal observation of cardiovascular diseases among people living with HIV in Lango Sub-region, Northern-Uganda.
REFNo: HS5900ES

Primary Objective
Assess the burden, risks and correlates of cardiovascular diseases (CVD) among people living with HIV (PLWH) in Northern Uganda to inform strategies for prevention, care and treatment in Sub-Saharan Africa.
The primary objective will be achieved through several secondary an explorative objective themed around forming a comprehensive understanding of the epidemiological, clinical, socio-behavioural, immunological, genetic, and microbiome-related factors influencing CVD among PLWH. The secondary and exploratory objectives are detailed in the attached protocol
 Uganda 2025-07-04 13:54:27 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sam Ononge
ID: UNCST-2020-R000328
 A CLINICAL TRIAL TO EVALUATE THE PERFORMANCE AND SAFETY OFTHE WEKEBERE SYSTEM FOR MONITORING FETAL WELLBEING DURING LABOUR
REFNo: HS3407ES

The overall objective of this study is to demonstrate safety and performance of wekebere fetal monitoring system.

Specific Objectives
To determine accuracy of wekebere fetal monitoring in comparison with gold standard. To determine the safety of wekebere system
To determine’ uterine contractions

 Uganda 2025-06-30 9:35:11 2028-06-30 Medical and Health Sciences Clinical Trial Non-degree Award
Felix Bongomin
ID: UNCST-2020-R014224
 LIAISON® QuantiFERON®-TB Gold Plus II for the Diagnosis of Active and Latent Tuberculosis in Uganda
REFNo: HS6213ES

To evaluate the automated LIAISON® QuantiFERON® -TB Gold plus II immunoassay for the detection of IFN-γ in human lithium heparin plasma from subjects at low risk for M. tuberculosis infection, mixed risk for M. tuberculosis infection and with active TB disease.,
 Uganda 2025-06-30 9:16:34 2028-06-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
 Retrospective Analysis of RSV RTI Prevalence, Coinfections, and Risk Factors among Older Adults in Uganda: A Study Based on Sentinel Surveillance Data
REFNo: HS5423ES

Objectives
General Objective
To determine the prevalence, associated factors, and coinfection patterns of Respiratory Syncytial Virus (RSV) respiratory tract infections (RTI) among adults aged 60 and above in Uganda using sentinel surveillance data.
Specific Objectives
1. To determine the prevalence and seasonal trends of RSV RTI among older adults in Uganda using data collected from sentinel surveillance sites
2. To examine the relationship between comorbid conditions such as cardiovascular disease, diabetes, and chronic kidney disease, and the severity of RSV RTI among older adults in Uganda.
3. To determine the prevalence of coinfections with other respiratory viruses—SARS-CoV-2, Influenza A/B, and Pandemic A(H1N1) 2009—among older adults with RSV RTIs in Uganda.
4. To assess the association between coinfections with other respiratory viruses —SARS-CoV-2, Influenza A/B, and Pandemic A(H1N1) 2009— and clinical outcomes, including disease severity, hospitalization rates, and mortality, among older adults with RSV RTIs in Uganda.

 Uganda 2025-06-30 9:14:46 2028-06-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
 OPTIMAH Study: OPTImizing Malaria And HIV treatment in a shifting landscape in Africa
REFNo: HS6165ES

PRIMARY OBJECTIVES
1. Assess the impact of HIV/DTG on weight gain (BMI) in Ugandan children ages 5 to 17 years of age over two years of follow-up.
2. Assess for PK drug-drug interactions between the two most widely used ACTs
(AL or AS-AQ) and DTG in longitudinal cohorts of HIV-uninfected children and CLHIV living in a high endemic malaria region (Busia).
3. To assess the 28- and 42-day efficacy of AL and AS-AQ for the treatment of uncomplicated malaria in children with and without HIV in a setting where artemisinin resistance has emerged.

SECONDARY OBJECTIVES
1. To assess the impacts of DTG on changes in body composition, waist circumference, and metabolic derangements over 2-years of longitudinal follow-up.
2. To assess the impact of repeated malaria infection on changes in weight gain in CLHIV on DTG (comparing HIV-infected cohorts in Busia and Kampala).
3. To determine if changes in DTG PK exposure in the presence of repeated courses of ACTs are associated with impacts on virologic control (pharmacodynamics).
4. To assess for the development of dolutegravir-associated resistance mutations over two years of follow-up.
5. To determine if changes in ACT exposure in the presence of daily DTG for HIV treatment are associated with impacts on malaria treatment outcomes.
6. To critically compare the PK exposure of artemether, artesunate, and DHA in the context of the two leading ACTs in Africa and assess for associations between the PK exposure of artemisinin derivatives as drivers of parasitologic outcomes such as parasite clearance rates for artemisinin-sensitive and resistant infections.
7. To assess levels of gametocytemia in children with and without HIV infection and with artemisinin-sensitive and -resistant infections
8. To determine if repeated course of AL and AS-AQ are associated with selection of resistance-associated mutations to the partner drugs and/or the artemisinin component.
9. To identify novel mutations in known and/or putative loci associated with resistance to artemisinins, lumefantrine, and amodiaquine using amplicon-based sequencing and/or other genotyping methods.
10. To assess the exposure of unbound DTG, lumefantrine, and DEAQ and association with clinical outcomes (viral load or parasitemia)



 Uganda 2025-06-26 23:59:42 2028-06-26 Medical and Health Sciences Clinical Trial Non-degree Award
Daniel Magumba
ID: UNCST-2025-R018334
 PEDESTRIAN ROAD SAFETY IN KAMPALA: A MIXED METHODS STUDY OF THE WALKABILITY OF KAMPALA’S ROAD INFRASTRUCTURE
REFNo: HS6064ES

1.To assess the Walkability of Kampala City’s Road infrastructure.
2.To explore stakeholder perceptions on pedestrian safety and walkability of Kampala city.

 Uganda 2025-06-26 23:54:31 2028-06-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charlot Diepvens
ID: UNCST-2025-R017733
 Demand-side enablers and barriers to epidemic preparedness: a mixed-method approach to understand priorities, acceptance and effective strategies for Ebola vaccines
REFNo: HS6132ES

The objective of this study is to examine demand-side factors that influence (enable or hinder) epidemic preparedness, with a focus on licensed Ebola vaccines. Specifically, it aims to visually identify and map key influencing factors, and to adequately translate their effects into quantitative models. This translation is critical, as decision-makers frequently rely on models—such as disease transmission models—to guide outbreak response strategies. Modeling has the potential to demonstrate the impact of specific interventions (e.g., additional training, improved guidelines, or the provision of dedicated funding) on vaccine use. This case study explores priorities and acceptance regarding licensed Ebola vaccines among decision makers. It also examines how these perceptions shift under different vaccination strategies, including reactive vaccination (during an outbreak) versus preventive vaccination (outside of an outbreak). More specifically, the studies objectives are to: 1. Identify and map key influences or determinants of vaccine use in Uganda through a conceptual systems diagram (e.g., perceptions of personal risk, fear of vaccine side effects), building on key informant interviews and group model building workshops. 2. Develop and validate a quantitative simulation model evaluating the impact of various vaccination strategies and interventions on vaccine use over time. 3. Derive insights from the diagram and model to inform policy and strategic decision-making at local and national levels regarding Ebola vaccine implementation. In short, the study will develop a visual representation of the problem space that can guide both policy and practice.
 Belgium 2025-06-26 23:52:36 2028-06-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 Socio-Cultural and Anthropological Perspectives on Child Feeding and Care, Food Consumption Habits, Dietary Patterns and Purchasing Behaviours in Uganda
REFNo: HS5843ES

Examine similarities and differences in caregiving practices that affect children’s nutrition across high-producing agricultural areas, pastoral regions, and urban landscapes,Explore the current perception of social behaviour change communication on complementary feeding.,Assess household dietary and food consumption behaviour,Examine caregivers\' purchasing habits and children’s food preferences, considering economic and cultural factors.,To gather comprehensive anthropological data on the dietary habits of children under 2 and the purchasing behaviours of caregivers in the districts of Kamwenge, Napak, and the urban areas of Kampala,
 Uganda 2025-06-26 23:51:22 2028-06-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SEDRIC NABAASA NKUBA
ID: UNCST-2024-R016326
 Peer Influence, Alcohol Use and Risky Sexual Behaviors among Adolescent Students in Secondary Schools in Greater Mbarara
REFNo: SS3934ES

1. To explore the gender difference in prevalence of risky sexual behaviors among adolescent students in secondary schools in greater Mbarara.
2. To establish impacts of peer influence on risky sexual behaviors among adolescent students in secondary schools in greater Mbarara.
3. To determine the mediation effects of alcohol us on the relationship between peer influence and risk sexual behaviors among adolescent students in secondary schools in greater Mbarara.
4. To explore the perceptions of adolescent students in controlling risk sexual behaviors in secondary schools in greater Mbarara

 Uganda 2025-06-25 13:34:21 2028-06-25 Social Science and Humanities Non-Clinical Trial Degree Award
Victor Musiime
ID: UNCST-2021-R013794
 Understanding Post-Discharge Mortality in children living with HIV who are hospitalized (SUPPORT1-PDM)
REFNo: HS6005ES

1. To assess the impact of an improved follow-up on reducing PDM in CLHIV 2. To evaluate the performance of disease severity biomarkers in this specific population to predict PDM 3. To analyze changes in serial measurements of CMV and potential association with PDM at day +360 in CLHIV 4. To describe the number of children with persistent detection of a specific respiratory pathogen 5. To describe the number of children with persistent detection of specific gastrointestinal (GI) pathogens 6. To describe the number of cases of histoplasmosis in CLHIV, its clinical characteristics, and outcomes in the identified cases, up to +360 days after discharge 7. To describe the prevalence of MDR colonization at enrollment, the microorganism isolated, and the duration of the colonization 8. To describe the main characteristics of readmissions, deaths and morbidity during 1-year follow-up after enrollment
 Uganda 2025-06-25 13:30:24 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIAN APAKO
ID: UNCST-2024-R004399
 LUNAS as a versatile and simple technique for malaria testing in a high transmission, rural setting
REFNo: HS5918ES

Primary objective - To determine the diagnostic accuracy of LUNAS POCT for malaria compared to common routine malaria testing (RDT and microscopy) during standard patient care in malaria-suspected individuals presenting at Kumi Hospital, Kumi, Uganda. Secondary objectives - To determine the diagnostic accuracy of LUNAS POCT for malaria compared to a commercial LAMP test - To determine the prevalence of malaria infections categorized by Plasmodium species. - To determine the correlation between time to positivity of both LAMP and LUNAS and parasitaemia as assessed by reference microscopy. - To determine the prevalence of P. falciparum harbouring deletions or mutations of the pfhrp2/3 gene in study participants, who have a P. falciparum infection with a parasitaemia as assessed by reference microscopy but a negative Pf HRP2/3 RDT result. - To determine the prevalence of Pf kelch13 (K13) gene mutations, which have been associated with resistance to artemisinin. - To determine the effectiveness of dried blood spots (DBS) for long term storage and transport of patient samples at ambient temperature for PCR testing.
Uganda 2025-06-25 13:26:35 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catherine Atuhaire
ID: UNCST-2021-R013090
 MATERNAL INFANT BONDING AND BREAST-FEEDING OUTCOMES IN UGANDAN MOTHERS DIAGNOSED WITH POSTPARTUM DEPRESSION IN PUBLIC HEALTH FACILITIES IN MBARARA DISTRICT, SOUTH WESTERN UGANDA
REFNo: HS5848ES

1. To determine the prevalence of maternal bonding impairment among mothers diagnosed with PPD in a public health facility in Mbarara district, South western Uganda.
2. To determine the breast-feeding outcomes of children born to mothers diagnosed with PPD in a public health facility in Mbarara district, South western Uganda.
3. To explore the lived bonding and breast-feeding experiences of mothers Diagnosed with PPD in a public health facility in Mbarara district, South western Uganda

 Uganda 2025-06-25 13:21:19 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve Wabule
ID: UNCST-2024-R004285
 DRIVERS OF NO-SHOWS FOR AMBULATORY APPENDECTOMY AMONG PATIENTS SCHEDULED FOR AMBULATORY APPENDECTOMY AT KYABIRWA SURGICAL CENTER
REFNo: HS6046ES

To establish the institutional drivers of no-shows for ambulatory appendectomy among patients scheduled for ambulatory appendectomy at Kyabirwa surgical center,To determine the patient-related drivers of no-shows for ambulatory appendectomy among patients scheduled for ambulatory appendectomy at Kyabirwa surgical center,To determine the prevalence of no-shows for ambulatory appendectomy among patients seeking ambulatory surgery at Kyabirwa surgical center,To assess the drivers of no-shows for ambulatory appendectomy among patients scheduled for ambulatory appendectomy at Kyabirwa surgical center,
 Uganda 2025-06-25 13:19:11 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Atek kagirita
ID: UNCST-2024-R015689
 LABORATORY SYSTEM RESILIENCE TO CORONAVIRUS DISEASE-19 OUTBREAK; ITS PREDICTORS, POLICY, AND PRIVATE SECTOR SUPPORT IN UGANDA
REFNo: HS6101ES

General objective
To assess the level of laboratory system resilience to COVID-19 disease outbreak, its predictors, appropriateness of policies to support it, and capacity of private sector laboratories to impact it in Uganda
4.2.2 Specific objectives
1. To determine the level and characteristics of resilience among licensed / accredited COVID-19 testing laboratories in Uganda.
2. To establish the predictors of resilience among licensed / accredited COVID-19 testing laboratories in Uganda.
3. To describe private sector laboratory capacity to contribute to national laboratory system resilience during the COVID-19 pandemic outbreaks
4. To appraise the appropriateness of current/emerging policies to support laboratory resilience during the COVID-19 pandemic outbreaks
 Uganda 2025-06-23 13:30:18 2028-06-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
 Development of context-appropriate approaches for the recruitment and retention of women of childbearing age and pregnant women in antimalarial clinical trials
REFNo: HS6036ES

1. To understand the context, socio-cultural practices and beliefs around early pregnancy as well as collecting experience with and/or perception of previous clinical trials to inform the development of culturally acceptable and understandable communication materials about the SAFIRE trial, including the information sheets for obtaining consent.
2. To identify factors and individuals that may influence WOCBA and pregnant women’s decision-making around participation and retention in the clinical trial to be addressed as part of project procedures and communications.
3. To explore approaches for facilitating the inclusion of WOCBA and pregnant women (in early pregnancy) in the clinical trial, based on the findings from objective 2.
4. To identify key stakeholders (including household decision-makers, community leaders and opinion shapers, health sector actors), from community to national levels, to be included and involved in the community engagement strategy prior to trial implementation.

 Uganda 2025-06-20 9:25:32 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rita Nakalega
ID: UNCST-2019-R000599
 Exploring Neuro-Vascular Biomarkers in Young Adults with lifelong HIV and without HIV in Uganda: Insights from Carotid Ultrasound
REFNo: HS6038ES

Exploratory objectives/aims: To determine the prevalence of and relationships between HIV infection, carotid pathology, neurological and neurocognitive function, and serum markers of cardiovascular health and inflammation in a population of young adults living with HIV in Uganda who acquired the infection perinatally as well as uninfected age-matched controls,Secondary objective (Aim 2): To determine the prevalence of cognitive dysfunction, as determined by a battery of cognitive evaluations, of a population of young adults living with HIV in Uganda who acquired the infection perinatally, relative to uninfected age-matched controls.,Primary objective (Aim 1): To determine the prevalence of carotid pathology, as determined by ultrasound-based measurement of intima-media thickness (IMT), in a population of young adults living with HIV in Uganda who acquired the infection perinatally, relative to uninfected age-matched controls.,
 Uganda 2025-06-20 9:22:24 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kiel McGowan
ID: UNCST-2025-R017284
 Prevalence and patterns of coinfection with malaria and soil transmitted helminths among school-aged children in rural Northern Uganda: A cross-sectional study
REFNo: HS6039ES

To measure the prevalence of coinfection with malaria and STH among school-aged children and to identify factors that may be associated with infection.
 USA 2025-06-20 9:16:14 2028-06-20 Medical and Health Sciences Non-Clinical Trial Degree Award
MARY AGUNLOYE OLAOLUWA
ID: UNCST-2024-R003434
 EVALUATION OF THE ACTIVITIES OF LEAF EXTRACTS OF AVOCADO (Persea americana Mill.) IN HIGH-FAT DIET/ LOW- DOSE STREPTOZOTOCIN - INDUCED TYPE 2 DIABETES MELLITUS IN WISTAR RATS
REFNo: HS5401ES

1. To screen aqueous, ethyl acetate, and ethanol leave extracts of p. americana Mill for anti-hyperglycemic activity
2. To assess the anti-diabetic potential of selected extract in high-fat diet/low-dose streptozotocin-induced T2DM in Wistar rats in a dose dependent pattern, and identify it mechanism of action
3. To perform phytochemical screening and metabolite profiling of the selected bioactive extracts through integrated FT-IR, LC-MS and GC-MS
4. To assess the in silico interactions of compounds of avocado leaf with selected drug targets in type II diabetes.
5. To evaluate the biological activities of the in silico hit compounds using in vitro and in vivo analyses

Nigeria 2025-06-20 9:03:03 2028-06-20 Medical and Health Sciences Non-Clinical Trial Degree Award
GEOFFREYEDWIN SEMAMBO
ID: UNCST-2024-R015519
 prevalence and factors associated with Adverse maternal outcomes among emergency obstetric referrals delivered at Mbarara regional referral Hospital
REFNo: HS5740ES

To determine the factors associated with adverse maternal outcomes among emergency obstetric referrals at Mbarara Regional Referral Hospital,To describe the adverse maternal outcomes among emergency obstetric referrals delivered at Mbarara Regional Referral Hospital,To determine the prevalence of adverse maternal outcomes among emergency obstetric referrals delivered at Mbarara Regional Referral Hospital, To determine the prevalence and factors associated with adverse maternal outcomes among emergency obstetric referrals delivered at Mbarara Regional Referral Hospital,
 Uganda 2025-06-20 8:55:52 2028-06-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Gloria Lubega
ID: UNCST-2025-R017180
 Understanding HIV vertical transmission in Uganda in a population of urban mothers in the era of Dolutegravir based antiretroviral therapy(VERT)
REFNo: HS6095ES

Quantitative Objectives I. To identify level of utilisation of PMTCT and EID services among mothers living with HIV. II. To assess the factors associated with utilization of PMTCT services and EID services among mothers living with HIV. III. To identify factors associated with HIV vertical transmission in the era of Dolutegravir based therapy among mothers living with HIV. IV. To determine the proportion of pregnant women diagnosed with HIV that were linked to care and the time taken from HIV diagnosis to linkage to care among mothers living with HIV. Qualitative Objectives 1. To explore the experiences of women in the PMTCT program, including. • Barriers and facilitators for utilizing the program. • Adherence to instructions such as breastfeeding practices. • And the role of close relationships (partner, family and community members) in supporting women’s participation in PMTCT. 2. To obtain suggestions that can potentially improve the implementation of the PMTCT program
Uganda 2025-06-20 8:53:57 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Annah Tugaineyo
ID: UNCST-2024-R016504
 WORKPLACE EQUITY, PARTICIPATION IN STAFF COMMITTEES, STAFF WELFARE AND JOB SATISFACTION OF ACADEMIC STAFF IN PUBLIC AND PRIVATE UNIVERSITIES IN WESTERN UGANDA
REFNo: SS3835ES

-To examine the differences in workplace equity between academic staff in public and private universities in Western Uganda.

-To assess the underlying factors that stimulate job satisfaction among academic staff in public and private universities in western Uganda

-To analyze the differences in participation in staff committees between academic staff in public and private universities in Western Uganda.

-To determine the influence of workplace equity on job satisfaction among academic staff in public and private universities in western Uganda.

-To assess the mediating role of participation in staff committees in the relationship between workplace equity and job satisfaction in public and private universities in western Uganda.

-To investigate the mediating role of staff welfare in the relationship between workplace equity and job satisfaction in public and private universities in western Uganda.

 Uganda 2025-06-20 8:47:35 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
Anne Mette Kjaer
ID: UNCST-2024-R015303
 The Political Economy of Local Food System Governance: Impacts on climate -Vulnerable communities in Lake Victoria Border Region
REFNo: SS3899ES

1. Understanding and mapping national food governance ie policy initiatives, decisions and processes affecting food and livelihood security of climate-vulnerable communities in lake Victoria border region (WP1)
2. Understanding the implementation processes of these food system policies and decision with a focus on the effect of local government autonomy and capacity to address the food and livelihood of climate-vulnerable communities, and the nature of state-community encouters in these processes (WP2)
3. Understanding the lived experiences of food and livelihood security among the climate-vulnerable communities in Lake Victoria region, the perceptions they have of local and national food system policies, and the role these communities play in food system governance
 Denmark 2025-06-20 8:43:55 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jolly  Kamugisha G.K.
ID: UNCST-2023-R005715
 Performance and Factors Affecting the Implementation of the Integrated Management of Acute Malnutrition Programme: A Study of Kampala, Mukono, Wakiso and Kayunga Districts
REFNo: HS6084ES

5. To document the lessons learnt and best practices during implementation of the IMAM program in the four target districts during the calendar year 2022 and 2023.,4. To establish factors that affect the utilization of IMAM services in the four target districts.,3. To determine factors influencing treatment outcomes of children with wasting in the four target districts.,2. To determine the performances of the integrated management of acute malnutrition program in the four target districts during the calendar year 2022 and 2023.,1. To identify the communities contributing to a high burden of childhood wasting caseload in health facilities in four target districts (Kampala, Mukono, Wakiso and Kayunga),The overall objective of this study is to assess the nutrition service delivery and factors influencing utilization of the IMAM programme in Kampala, Mukono, Wakiso and Kayunga districts,
 Uganda 2025-06-20 8:41:29 2028-06-20 Medical and Health Sciences Clinical Trial Non-degree Award
Evan Borkum
ID: UNCST-2025-R016987
 Evaluation of cash and cash plus intervention in Nakivale refugee settlement, Uganda
REFNo: SS3849ES

The non-profit organization GiveDirectly plans to implement a cash-plus program in Nakivale refugee settlement, which will supplement a large unconditional cash transfer with demand-driven skills training and apprenticeship; business coaching, mentoring, and entrepreneurship support; and access to financial services and financial literacy training. The objective of the study is to rigorously assess the impact of the program on household wellbeing through a randomized controlled trial.
Italy 2025-06-20 8:36:56 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
 EVALUATION OF A PILOT PROJECT TO EXPAND ACCESS TO THE IMPLANT FAMILY PLANNING METHOD THROUGH COMMUNITY HEALTH EXTENSION WORKERS IN SELECTED DISTRICTS IN UGANDA
REFNo: HS5966ES

3. To determine competence of the CHEWs regarding insertion and removal of implants following training.,2. To assess the acceptability of the community-based implant by CHEWs among the stakeholders (health workers at the facility, FP clients in the community) ,1. To explore the perceptions of the stakeholders towards the implant provision task shifting to the CHEWs (stakeholders including the CHEWs, clients, health workers/ professionals and policy makers) ,The overall objective is to evaluate the implementation of a community-based implant intervention through training CHEWs on how to insert and remove implants, in order to understand the perceptions and acceptability of stakeholders towards task shifting the implants service provision to CHEWS, and determine the CHEWs attainment of competencies to insert and removal implants in the selected districts in Uganda,
 Uganda 2025-06-20 8:34:40 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julian Benedict Kuttig
ID: UNCST-2025-R018435
 Youth Participation, Representation, and Civic Engagement in the Context of Social Cohesion: The Case of Uganda Martyrs University Nkozi and Rajshahi University, Bangladesh.
REFNo: SS3956ES

1. To investigate how student civic engagement contributes to social cohesion within university and local communities. 2. To understand the factors that shape student civic agency, including cultural, institutional, and policy influences. 3. To explore how lessons learned from diverse contexts can challenge the global North/South dichotomy and provide transferable insights into fostering social cohesion. 4. To shed light on the unique spatial and social dynamics of secondary cities as sites of youth civic engagement, offering a counterbalance to strictly urban- or rural-centric research.
Germany 2025-06-20 8:26:29 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Cornelius Sendagire
ID: UNCST-2021-R004351
 Practice of Fluid Therapy in Critically Ill Invasively Ventilated Patients (PRoFLUID)––an International Multicenter Observational Cohort Study The PRoFLUID–investigators
REFNo: HS6063ES

3.1. General Objective To explore global practices in intravenous fluid and vasopressor therapy in invasively ventilated ICU patients. 3.2 Specific Objectives Describe the types and volumes of fluids administered in the first 3 and 7 days after initiation of invasive ventilation. Detail the timing, type, and duration of vasopressor and diuretic therapy. Assess daily urine output and cumulative fluid balances. Evaluate clinical outcomes (ventilation duration, ICU/hospital length of stay, and mortality). Compare practices across different geo-economic regions.
 Uganda 2025-06-20 8:20:52 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ellen Asiimwe
ID: UNCST-2024-R002415
 Academic demands and Mental Wellbeing of Upper Primary Learners in Uganda. A study of Government and Private Schools in Mukono Municipality.
REFNo: SS3902ES

To explore the learners’ experiences of extracurricular activities in Mukono municipality primary schools,To compare the effect of academic demands and mental wellbeing on upper class learners from government schools and private schools,To assess how the length of time (early start and late end) influences learners’ mental wellbeing,To establish how high expectations affect learners’ mental wellbeing, To assess the relationship between academic demands and mental wellbeing from of upper class learners in Mukono Municipality Schools.,
 Uganda 2025-06-20 7:56:25 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rachel  Kabunga Rehema
ID: UNCST-2021-R005043
 Investigating the Feasibility of Implementing an Automated Diabetic Retinopathy Screening Algorithm in Southwestern Uganda
REFNo: HS5979ES

To describe the existing AI-based DR screening algorithms and their infrastructure
requirements based on published scholarly evidence globally.
2. To assess the existing capacity within the health facilities to support the implementation of an
AI-based DR screening system in Southwestern Uganda,
3. To assess the performance of the most context-appropriate existing AI-based DR screening
algorithms in Southwestern Uganda.
 Uganda 2025-06-20 7:50:07 2028-06-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Elizabeth Nyboer Ann
ID: UNCST-2023-R005929
 Social license and access in aquaculture: documenting perceptions of nutritional, economic, and environmental risks and benefits in Lake Victoria's fisheries
REFNo: SS3903ES

(1) document stakeholder views on the environmental, economic, and nutritional risks and benefits, (2) quantify stakeholder proximity to environmental risks, and (3) examine how different farm types affect risks, benefits, and access to those benefits for various stakeholders
 Canada 2025-06-20 7:47:42 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Suubi4PrEP: Improving PrEP Access and Adherence Among Adolescent Girls and Young Women in Uganda
REFNo: SS3990ES

Suubi4PrEP will examine the effect of a multilevel intervention, combining HIV risk reduction that incorporates sessions on PrEP, peer supporters with lived experiences to facilitate linkage to and continued care, and economic empowerment components targeting financial barriers associated with PrEP access, PrEP initiation, uptake and adherence among AGYW in Uganda. Study aims are:

Aim 1: Examine the impact of Suubi4PrEP on PrEP initiation (primary outcome); and PrEP adherence (secondary outcome).

Aim 2: Examine the effect of Suubi4PrEP on hypothesized mechanisms of change (financial stability, PrEP stigma, self-efficacy, depressive symptoms, and social support) and intervention mediation.

Aim 3: Use mixed methods to explore multi-level factors that influence PrEP initiation and adherence.

Aim 4: Assess the cost and cost-effectiveness of the interventions.

Uganda 2025-06-20 7:41:25 2028-06-20 Social Science and Humanities Clinical Trial Non-degree Award
Dorothy Akongo
ID: UNCST-2023-R007564
 Pediatric Epilepsy in Busoga Region, Uganda – current management and factors associated with drug adherence and seizure control
REFNo: HS6004ES

The overall aim is to assess the current ability to diagnose and manage childhood epilepsy in
health facilities at different levels in Busoga region, Uganda and to describe pediatric epilepsy
patients followed at a Ugandan regional referral hospital to identify factors associated with
seizure control and epilepsy drug adherence.
 Uganda 2025-06-20 7:37:23 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jesca Audo Harriet
ID: UNCST-2019-R000209
 STUDENT LEARNING ACTIVITIES IN BIOLOGY LESSONS AS MEDIATORS OF SELF-EFFICACY AND GENERIC SKILLS IN UGANDA’S NEW LOWER SECONDARY CURRICULUM
REFNo: SS3915ES

The following objectives will serve as the study's direction. 1.To determine the level of student learning activities designed for students during Biology lessons in the lower secondary schools. 2.To determine the level of acquisition of generic skills among students during Biology lessons in the lower secondary schools. 3.To investigate the relationship between self-efficacy and student learning activities during Biology lessons in the lower secondary schools. 4.To examine the relationship between self-efficacy and generic skills acquisition among students during Biology lessons in the lower secondary school. 5.To examine the relationship between student learning activities and generic skills acquisition among students during Biology lessons in in the lower secondary schools. To investigate the mediating effect of student learning activities in relation to self-efficacy and generic skills acquisition among students during Biology lessons in the lower secondary schools.
 Uganda 2025-06-20 7:34:34 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 VAC52150EBL4006 entitled: “Prospective, Multi-country, Non-interventional, Case-control Study with Test-negative Controls to Estimate the Effectiveness of the Ad26.ZEBOV, MVA-BN-Filo Vaccine Regimen Against Ebola Virus Disease (EVD) in Real-world Setting
REFNo: HS6053ES

The primary objective of this trial is to estimate the vaccine effectiveness of the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen or a booster dose of Ad26.ZEBOV against polymerase chain reaction (PCR)-confirmed EVD in adults and children
 Uganda 2025-06-20 19:06:06 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Justus Turamyomwe
ID: UNCST-2025-R019115
 A Morphosyntactic Analysis of Runyankore-Rukiga Associative Nominals
REFNo: SS3955ES

1. To examine how associative nominals are marked in Runyankore-Rukiga
2. To Explicate how Runyankore-Rukiga nominals are derived.
3.To establish the specific functions of associative modifiers in Runyankore-Rukiga associative constructions.
 Uganda 2025-06-20 19:00:22 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
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