Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Justine Nakintu
ID: UNCST-2019-R001223
Nutrient enrichment of Maize Flour for a Dietary Balanced Breakfast: Fortification with Jackfruit
REFNo: A747ES

i. To determine concentrations of proteins, vitamins, minerals and phytochemicals in the different varieties of jackfruit
ii. To fortify maize flour with different proportions of jackfruit and determine the concentrations of proteins, vitamins, mineral and other phytochemicals in un-fortified maize flour and jackfruit-fortified maize flour
iii. To establish the sensory acceptability of porridge made from jackfruit fortified maize flour

2026-04-02 18:00:32 2029-04-02 Agricultural Sciences Non-Clinical Trial Non-degree Award
Lynn Tar Janet Gutu
ID:
An AI system to assist the visually and auditory impaired by generating speech from text queries and vice versa for Uganda’s local languages
REFNo: SIR633ES

To pen source the collected linguistic datasets and baseline models to support future research, foster collaboration, and create a foundation for broader AI innovation in low-resource languages.,To develop and deploy a user-friendly platform that enables easy and inclusive access to the system for impaired and non-impaired users alike.,To build and train multilingual TTS and LLM models for at least five Ugandan languages. ,To develop and deploy a locally managed AI system with multilingual TTS and LLM capabilities that supports Uganda’s most widely spoken indigenous languages, with a particular focus on enhancing accessibility for visually and auditory impaired communities, while promoting inclusivity, education, and digital innovation.,
Uganda 2026-04-02 17:59:20 2029-04-02 Engineering and Technology Non-degree Award
Ekom Etukudo Monday
ID: UNCST-2025-R021054
Neuroprotective Potential of Syzygium aromaticum Against Mercuric Chloride-Induced Brain Toxicity in Mice
REFNo: HS7231ES

General Objective
To evaluate the neuroprotective potential of Syzygium aromaticum against mercuric chloride-induced brain toxicity in mice.

Specific Objectives
This study's specific objectives will be to:
(i) Phytochemically characterize Syzygium aromaticum and predict the pharmacokinetic and toxicological properties of its major metabolites using computational tools.
(ii) Determine molecular interactions between the key phytometabolites of Syzygium
aromaticum and neuronal receptors (NMDA and GABA-A) implicated in mercuric chloride-induced neurotoxicity through molecular docking.
(iii) Evaluate the neurobehavioral and biochemical effects of Syzygium aromaticum pretreated and mercuric chloride-exposed mice, focusing on motor coordination, memory performance, oxidative stress, and lipid peroxidation biomarkers.
(iv) Demonstrate histological alterations in the cerebellar cortex and hippocampus of Syzygium aromaticum pretreated and mercuric chloride-exposed mice, by assessing cellular forms.
(v) Demonstrate astroglial activation and neuronal injury in the cerebellar cortex and hippocampus of Syzygium aromaticum pretreated and mercuric chloride-exposed mice using immunohistochemical markers for Glial Fibrillary Acidic Protein (GFAP) and Neuronal Specific Enolase (NSE).
Uganda 2026-04-02 17:56:12 2029-04-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Joseph Mugisha Okello
ID: UNCST-2022-R009461
Feasibility of using telephone interviews for health surveillance in an open population cohort: A cluster randomised non-inferiority trial.
REFNo: HS7309ES

Study aim
To assess the feasibility of using telephone interviews in conducting survey data collection that includes the assessment of family planning needs in the Kyamulibwa General Population Cohort.

Specific objectives

To evaluate the acceptability of telephone interviews among GPC participants, including interview completion rates, and willingness to participate via phone.

To compare data quality and completeness between telephone interviews and face-to-face interviews, focusing on key demographic and health indicators.

To identify logistical and operational challenges associated with conducting telephone-based data collection, such as mobile phone access, network coverage, call success rates, and duration.
iv.
To explore the economic and financial cost of using telephone interviews for running health surveillance compared to traditional face-to-face interviews.

To understand demographic and socioeconomic factors influencing completion rates, such as age, gender, education level, or social economic status.
Uganda 2026-04-02 17:54:29 2029-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mohamed Sesay
ID:
Traditional authorities in contemporary governance systems in Africa: Uganda, Ghana, and Sierra Leone in comparative perspectives
REFNo: SS5086ES

The main purpose of this comparative study of Uganda, Sierra Leone, and Ghana is to compare and contrast how traditional rulers relate with the state in contemporary governance systems.
The specific objectives of this study include the following:
• Compare the nature and strength of traditional authority in Uganda, Sierra Leone, and Ghana so as to understand how they have evolved and adapted to changes in contemporary governance
• Examine how chiefs exercise their authority in relations to other powerholders in specific contexts taking into account changing political, socioeconomic, and cultural
circumstances
• Trace the evolution of chiefs' relations with other authorities in contemporary times both at the national and subnational levels of governance.
• Analyze the comparative effect of reform policies on chiefs, including initiatives intended to liberal-democratic standards of governance


Sierra Leone 2026-04-02 17:45:23 2029-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
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