Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
JOAN KABAYAMBI PROSE
ID:
Exploring Implementation Experiences to Adapt Digitized Payment of Community Health Workers: A Case Study of Benin and Uganda
REFNo: HS2926ES

The general objective of the study is to document the experiences of using DFS, identify good practices for the planning and implementation of gender-sensitive, national and sustainable digital health payment (DHP) of CHWs. ,iii) Design, using the identified good practices, a prototype for effective, gender-sensitive, and sustainable digital payment systems for CHWs in resource-constrained settings such as Benin and Uganda,ii) Assess the level of readiness and requirements for DHP of CHWs based on the experiences of using digital payment systems of community health workers during vaccination campaigns in Benin and Uganda,i) Understand the experiences, challenges, and opportunities of digital health payment systems for community health workers in Sub-Saharan Africa in immunization campaigns taking into account gender aspects ii) Assess the level of readiness and requirements for DHP of CHWs based on the experiences of using digital payment systems of community health workers during vaccination campaigns in Benin and Uganda iii) Design, using the identified good practices, a prototype for effective, gender-sensitive, and sustainable digital payment systems for CHWs in resource-constrained settings such as Benin and Uganda,
Uganda 2023-07-11 11:25:02 2026-07-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
Forced Labor Measurement Study: Ugandan Labor Migrants in the Middle East
REFNo: SS1872ES

Overall objective
To provide representative estimates of experiences of forced labor indicators among Ugandan migrant workers in the Middle East based on The International Conference of Labour Statisticians’ (ICLS) Guidelines concerning the measurement of forced labour, 2018.

Specific objectives

I. Explore the best way to interpret and operationalize the definitions presented in the guidelines
II. Explore how the ways in which questions are asked affects responses
III.Provide recommendations to improve questionnaire design and ultimately data quality

Uganda 2023-07-11 11:22:59 2026-07-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
joseph  mwizerwa
ID:
Promoting Cultural Humility Through a Collaborative Online Transcultural Education and Leadership Development for Nurses in the Global Community
REFNo: HS2856ES

3. Conduct a posttest (endline) survey to evaluate the success of the training intervention in improving the participants’ leadership and collaborative competencies.,2. Design and implement appropriate/customized learning activities/course content informed by the baseline survey results.,1. Carry out a pretest to understand the participants’ baseline collaborative and leadership competencies prior to the intervention.,Develop an assessment process to determine whether students (graduates and/or undergraduates) are achieving the planned global learning and leadership development outcomes.,Design learning activities and course content that will allow students to demonstrate global learning and leadership development outcomes,Initiate a course syllabus or co-curriculum revision process to define global learning and leadership development outcomes for a course or academic program for graduates and undergraduate nursing students.,
Uganda 2023-07-10 17:48:52 2026-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clovice Kankya
ID: UNCST-2020-R010154
Taxonomic Assessment of Selected Angiosperm Families in East Africa
REFNo: A318ES

Broad Objective
To provide a comprehensive study on the taxonomic and phylogenetic analysis of the Hydnoraceae, Poaceae, Viburnaceae, Velloziaceae, and Rutaceae species in East Africa.

Specific Objectives
a. To explore the inter-species diversity in Hydnoraceae from East Africa.
b. To produce the first revision of tribe Cynodonteae in the Flora of Central Africa.
c. To assess the taxonomic status of Sambucus L., (Viburnaceae) in East Africa.
d. To understand the taxonomic update and revision of the family Velloziaceae.
e. To provide a taxonomic revision of the genus Zanthoxylum and Vepris in East Africa.

Uganda 2023-07-10 17:24:14 2026-07-10 Agricultural Sciences Non-Clinical Trial Non-degree Award
Arthur  Mpimbaza
ID: UNCST-2022-R008866
Risk of contracting malaria among hospitalized patients at Jinja regional referral hospital, Uganda: a prospective cohort study.
REFNo: HS2918ES

The objective of this study is to determine the risk of hospitalized patients with non-malarial illnesses contracting malaria during their stay in hospital.
Uganda 2023-07-07 11:07:23 2026-07-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
A Phase 2/3, Open-Label Study of the Pharmacokinetics, Safety, and Antiviral Activity of the GS-9883/Emtricitabine/Tenofovir Alafenamide (GS9883/F/TAF) Fixed Dose Combination (FDC) in HIV-1 Infected Adolescents and Children.
REFNo: HS2931ES

The primary objective of this study is to confirm the dose of B/F/TAF FDC in HIV-1 infected pediatric participants, to confirm the dose of B/F/TAF TOS in HIV-1 infected pediatric participants and to evaluate the safety and tolerability these medications.
Uganda 2023-07-06 17:23:47 2026-07-06 Medical and Health Sciences Clinical Trial Non-degree Award
Mildred Nakanwagi Julian
ID: UNCST-2021-R013459
Relationship of Robusta coffee native diversity with the abiotic and biotic environment
REFNo: A290ES

i. To determine the level of diversity and patterns on the population structure of diverse coffee germplasm in Uganda
ii. To assess the degree of coherence between genetic and morphological variation across and within C. canephora populations in Uganda.
iii. To determine the influence of abiotic factors on adaptive genetic variation in wild C. canephora accessions across ecogeographic zones of Uganda.
iv. To determine the abundance of biotic resilience associated unique alleles among and within C. canephora populations from different natural forests in Uganda.

Uganda 2023-07-06 17:18:28 2026-07-06 Agricultural Sciences Non-Clinical Trial Degree Award
Christopher Daly
ID:
An Assessment of Maternal Recognition of Neonatal Sepsis following Implementation of Standardized Newborn Discharge Education in Western Uganda
REFNo: HS2902ES

The primary objective of this study is to identify whether implementing a newborn discharge education checklist and providing an educational module in the maternity ward setting will lead to improvement in mothers’ ability to identify the danger signs of neonatal illness. Secondary objectives will include identifying maternal barriers to education, identifying maternal opinions on educational needs, and identifying how mothers will seek care in case of neonatal sepsis concerns.
USA 2023-07-06 17:17:42 2026-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
EVALUATING THE EFFECT OF A LOW-COST FOETAL HEART RATE MONITOR AND EDUCATIONAL PACKAGE ON MONITORING INTERVALS AND NEWBORN OUTCOMES IN GULU DISTRICT.
REFNo: HS2868ES

1. To assess the effect of a low-cost Foetal Heart Rate Monitoring device (Moyo) on the Foetal Heart Rate monitoring intervals.
2. To assess the effect of a low-cost FHRM device (Moyo) on detection of fetal heart rate abnormalities
3. To evaluate the effect of the intervention package on immediate newborn outcomes
4. To explore health care providers experiences of Foetal Heart Rate Monitoring before and after the intervention.
Uganda 2023-07-06 17:16:36 2026-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nicholas Kilimani
ID: UNCST-2022-R010981
Supported childcare and women labor market participation in East Africa: Evidence from Uganda
REFNo: SS1689ES

Determine the impact of supported childcare programs on women labor market participation in Uganda.

Specific Objectives

a) Identify which childcare programs are better suited for workers across the different labour market segments.
b) Determine the extent to which supported childcare influences women labour market outcomes.
c) Identify whether supported childcare provides significant spillovers to other community members besides mothers’ participation in paid work.
d) Identify the sociocultural factors that influence women labour market participation.

Uganda 2023-07-06 17:15:03 2026-07-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID:
Manifestation of Cardiac & Kidney diseases among Adolescents and Young people living with HIV (MACK study).
REFNo: HS2907ES

General aim:
To assess Prevalence of Cardiac and kidney diseases among Adolescents and Young people living with HIV in Jinja Uganda and Dar Es Salaam Tanzania.
Primary objectives:
1. To determine the prevalence of Cardiac and Kidney diseases among Adolescents and Young people living with HIV attending ART clinics at TASO-Jinja Uganda and Mwananyamala referral Hospital -Dar es Salaam Tanzania
2. To describe the common manifestations of cardiac and kidney diseases among Adolescents and young people living with HIV attending ART clinics at TASO-Jinja Uganda and Mwananyamala referral Hospital -Dar es Salaam Tanzania
Secondary objectives
1. To determine behavioral risk factors associated with cardiovascular and renal diseases among adolescents and yound people living with HIV attending ART clinics at TASO-Jinja Uganda and Mwananyamala referral Hospital -Dar es Salaam Tanzania
2. To describe the effect of COVID-19 on the prevalence of Cardiac and renal diseases among Adolescents and young people living with HIV attending ART clinics at TASO-Jinja Uganda and Mwananyamala referral Hospital -Dar es Salaam Tanzania.

Uganda 2023-07-06 17:13:53 2026-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gerald Businge Bright
ID:
Median time to death and factors associated with post-discharge mortality in children under 5 years admitted with severe acute malnutrition at Mulago Hospital: A retrospective cohort study
REFNo: HS2948ES

Describe the commonest events preceding post-discharge mortality in children under 5 years admitted with severe acute malnutrition at Mulago Hospital.,Identify the median time to post-discharge death in children under 5 years admitted with severe acute malnutrition at Mulago hospital.,Identify the factors associated with post-discharge mortality among children aged less than 5 years admitted with severe acute malnutrition at Mulago Hospital.,Identify the factors associated with post-discharge mortality and the median time to death in children under 5 years admitted with severe acute malnutrition at Mulago Hospital, as well as medical events preceding these deaths.,
Uganda 2023-07-06 17:12:42 2026-07-06 Medical and Health Sciences Non-Clinical Trial Degree Award
William Kollie Saygbah
ID:
AMELIORATION OF SOIL ACIDITY FOR SUSTAINABLE CROP PRODUCTION ON FERRASOLS OF CENTRAL UGANDA
REFNo: A272ES

1. To map, sample and evaluate the chemical properties of Ferrasols of Central Uganda.

2. To determine the lime requirements for Ferrasols of Central Uganda.


3. To evaluate the effect of liming and crop performance on Ferrasols of Central Uganda

Liberia 2023-07-06 17:10:38 2026-07-06 Agricultural Sciences Non-Clinical Trial Degree Award
Vincent Odeke -
ID:
Prevalence of and factors associated with inappropriate antibiotic prescription in children under the age of 13 years at primary healthcare facilities in Bukedea district
REFNo: HS2819ES

4. To determine the health facility and prescriber-related factors associated with inappropriate antibiotic prescription in children under the age of 13 years at primary healthcare facilities in Bukedea district,3. To identify the treatment-related factors associated with inappropriate antibiotic prescription in children under the age of 13 years at primary healthcare facilities in Bukedea district,2. To determine the patient-related factors associated with inappropriate antibiotic prescription in children under the age of 13 years at primary healthcare facilities in Bukedea district,1. To assess the prevalence of inappropriate antibiotic prescription in children under the age of 13 years at primary healthcare facilities in Bukedea district,To assess the prevalence of and factors associated with inappropriate antibiotic prescription in children under the age of 13 years at primary healthcare facilities in Bukedea district,
Uganda 2023-07-06 17:09:23 2026-07-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Alfred Jatho
ID: UNCST-2021-R011710
Applying Science to Strengthen and Improve Systems for Cachexia Care in Uganda (ASSIST-CC)
REFNo: HS2656ES

: i). Increase awareness and knowledge of cancer cachexia among healthcare professionals and multidisciplinary teams involved in the care of patients with cachexia together with cancer cachexia patients; ii). To improve treatment outcomes of cancer patients with cachexia through the application of ESMO and ASCO guidelines in early diagnosis and provision of physiological and psychological care; iii). To improve patient, caregiver and healthcare professional communication through the application of the Patient-Clinician Communication ASCO Consensus Guideline in order to improve the quality of life of patients with cancer cachexia at Mbarara Regional Cancer Center, Mbarara regional referral hospital, Uganda Cancer Institute, Mulago, and Kawempe National referral hospitals.
Uganda 2023-07-06 17:07:49 2026-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Monica Swahn H
ID: UNCST-2021-R012004
TOPOWA Cohort Study
REFNo: HS2959ES

Through a prospective cohort of AGYW, determine if SeSTT modifies the pathways between proximal social and environmental stressors and mental health outcomes, through the RDoC constructs of negative valence, sustained threat, and arousal and regulatory systems. We will measure threat reactivity in fear conditioning, ratio of salivary cortisol, dehydroepiandrosterone (DHEA) and α-amylase, validate drug and alcohol use through urinalysis, sleep quality and environmental stressors (Garmin Vivoactive 3 wearable sensors, 5 daily diaries).,
USA 2023-07-06 17:06:28 2026-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wanambwa Joseph
ID: UNCST-2020-R014175
AN INFORMATION AND COMMUNICATION TECHNOLOGY-ENABLED MODEL FOR INCREASED VACCINE UPTAKE DURING PANDEMICS: A CASE OF UGANDA
REFNo: SIR233ES

iii. To evaluate the extent to which designed ICT-Enabled model supports increase in vaccine uptake during pandemics in Uganda.,ii. To design an ICT-Enabled model that supports increase in vaccine uptake during pandemics in Uganda ,i. To determine factors and requirements that influence use of information technology to increase vaccine uptake during pandemics in Uganda ,Specific objectives,The main objective of this study is to develop an Information and Communication Technology (ICT)-Enabled Model to support Increase in Vaccine Uptake during Pandemics in Uganda.,
Uganda 2023-07-05 11:52:14 2026-07-05 Engineering and Technology Non-Clinical Trial Degree Award
Suzan Nakkazi
ID:
A comparative study of Rural and Semi-rural Women’s Communication, Information, and Participation Needs in East Africa
REFNo: SS1833ES

To recommend what supports young women in their participation and to show how their voices can be amplified.,To examine how young women assess their own influence and possibilities to shape public discourse and to lobby for their own interests and needs,To identify the possible barriers (societal, cultural, religious, gender, personal) that may hinder young women’s participation in public discourse or decision-making.,To understand young women’s participation in public discourses and decision-making (including where they feel free/safe to speak and where not),To distinguish and explain the challenges young women face in terms of media literacy,To identify young women’s barriers/ challenges to the access to and usage of media, including media literacy,To identify young women’s information (including topic) needs/ interest as well as their preferred media and/ or media content,To understand the sources of information (besides classical media) and identify the type and frequency of media usage among young women,The primary objective of the study is to identify the communication, information and participation needs of young women in rural and semi-rural areas. Subsequently, the study results will be used to form the basis of DW Akademie’s project design for the innovation process / idea competition.,
Uganda 2023-07-05 11:51:02 2026-07-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Simon Opolot Peter
ID: UNCST-2023-R007481
Land Tenure Systems and Agricultural Productivity in Ngora District, Uganda
REFNo: SS1809ES

The specific objectives of the study are to:
i. Examine the effects of customary, freehold, and leasehold land tenure systems on agricultural productivity in Ngora district.
ii. Determine which land tenure system or systems; customary, freehold, and leasehold; has the most impact on agricultural productivity in Ngora district.
iii. Investigate how the customary, freehold, and leasehold land tenure systems in Ngora district can be reformed to increase agricultural productivity.
iv. Identify initiatives that can be integrated with land tenure systems; customary, freehold, and leasehold; to increase agricultural productivity in Ngora district.

Uganda 2023-07-05 11:48:59 2026-07-05 Social Science and Humanities Non-Clinical Trial Degree Award
Thomas McHale
ID: UNCST-2022-R008812
Optimizing the Dose of Flucytosine for Cryptococcal Meningitis
REFNo: HS2940ES

Determine if 50 mg/kg/day of 5-FC has a similar mortality benefit compared to 100 mg/kg/day,Reduce the cost and supply burden of treating an individual with cryptococcal meningitis,Determine if 50 mg/kg/day of 5-FC is a safer dosage compared to 100 mg/kg/day of 5-FC,Determine if 50 mg/kg/day of 5-FC is has a similar rate of cryptococcal clearance from CSF compared to 100 mg/kg/day,Determine the optimal dose of 5-FC for for management of induction phase of therapy for cryptococcal meningitis,
USA 2023-07-05 11:41:24 2026-07-05 Medical and Health Sciences Clinical Trial Degree Award
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