Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jakyoung Lee
ID: UNCST-2024-R016191
The Evaluation of the Capacity Building for Community Health Workers (CHWs) in Central Region of Uganda
REFNo: HS5548ES

● Assess progress relative to the project plan and suggest improvements in project execution. ● Establish strategies to enhance the quality of health worker training, community health activities, and other related actions. ● Review and adjust performance indicators based on the Project Design Matrix (PDM) and develop new key performance indicators. ● Formulate an exit strategy from a health system strengthening perspective to enhance the project's sustainability and effectiveness
South Korea 2025-02-20 18:53:36 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
COBIHA- A COMMUNITY BASED INTERVENTION AGAINST HARMFUL USE OF ALCOHOL IN A RURAL SETTING: A pilot study around lake Bunyonyi in Kigezi, Uganda
REFNo: HS5521ES

2.To explore reasons for harmful use of alcohol, and perceptions on effective and acceptable ways of reducing this.,1.To conduct a pilot survey to establish the level of harmful use of alcohol and factors associated with the behaviour , to fill the evidence gap on effective community interventions, the current burden of harmful use of alcohol, and community perceptions of the burden of harmful alcohol use in rural Uganda,
Uganda 2025-02-20 18:51:21 2028-02-20 Medical and Health Sciences Clinical Trial Non-degree Award
Alfred Jatho
ID: UNCST-2021-R011710
A Focus on Breast Cancer: Decentralizing Breast Cancer Early Detection through addressing barriers to accessing timely and quality care in Uganda and Zambia
REFNo: HS5551ES

How effective is the developed generic breast cancer training package in equipping
Primary and Community Health Workers with knowledge and skills to train, handle and
refer cases of Breast cancer in Arua and Mbarara health regions?
2. How effective is support supervision and mentorship towards improving the quality of
breast cancer services at primary and community health level?
3. What is the level of awareness and practice of breast self-examination by women
attending HFs in Mbarara and Arua health regions?
4. What is the association between breast cancer screening knowledge and practices of
women attending health facilities ?
Uganda 2025-02-20 18:31:56 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charlotte Bednarski Marie
ID: UNCST-2024-R003417
Transnational networks of care: international NGO management in Iganga, Uganda
REFNo: SS3628ES

PhD pre-dissertation research
USA 2025-02-20 18:29:52 2028-02-20 Social Science and Humanities Non-Clinical Trial Degree Award
KOBUSIINGYE FLORAH
ID: UNCST-2024-R001996
A MOBILE TEACHING-LEARNING FRAMEWORK FOR BRIDGING THE AGRICULTURAL EXTENSION GAP IN RESOURCE CONSTRAINED AREAS. A CASE STUDY OF KIGEZI SUB-REGION
REFNo: SIR464ES

Main Objective -To produce a comprehensive teaching-learning framework aimed at reducing the agricultural extension gap in the Kigezi region.

specific objectives
1. To evaluate current agricultural extension frameworks, identifying their strengths and weaknesses.
2. To design a mobile application framework that facilitates access to information, skills, and technology for farmers, extension officers, and other value chain actors.
3. To assess the feasibility and acceptability of the developed mobile agricultural extension application among farmers, extension officers, and other value chain actors.
Uganda 2025-02-20 18:27:15 2028-02-20 Engineering and Technology Non-Clinical Trial Degree Award
LOIS BAYIGGA
ID: UNCST-2024-R004310
PRE-CLINICAL TESTING OF FORWARD-ORIENTED GLOBIN-EXPRESSING LENTIVIRAL VECTOR
REFNo: HS5513ES

e) To determine the efficiency of magnetically assisted transduction in gene modified CD34+ cells, isolated from individuals with sickle cell disease or trait, using flow cytometry and real-time polymerase chain reaction (RT-PCR),d) To compare the efficiency of standard transduction to magnetically assisted transduction in CD34+ cells, isolated from individuals with sickle cell disease or trait, using a forward-oriented globin-expressing lentiviral vector using flow cytometry and real-time polymerase chain reaction (RT-PCR),c) To determine the presence of HbS mutation in the CD34 negative cells isolated from cord blood and red blood cell exchange products using hemoglobin electrophoresis.,b) To determine the yield, purity, and viability of CD34+ cells isolated from cord blood and red blood cell exchange products using multicolor flow cytometry ,a) To isolate hematopoietic stem and progenitor cells (CD34+) from cord blood and red blood cell exchange products using immunomagnetic-based method,To determine the efficacy of the forward-oriented globin-expressing lentiviral vector in HSPCs isolated from individuals with sickle cell disease or trait in Uganda,
Uganda 2025-02-20 18:26:20 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
Effect of non-communicable disease multimorbidity on TB treatment outcomes amogn TBHIV co-infected patients in Uganda
REFNo: HS5506ES

a) To determine the prevalence of, and factors associated with multimorbidity among people with TB and HIV
b) To determine the effect of NCD Multimorbidity on TB treatment outcomes among persons co-infected with HIV.

Uganda 2025-02-20 17:58:06 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Okech Apio
ID: UNCST-2022-R011031
Epidemiology of Malaria Infection in Sub-Saharan African Countries
REFNo: HS5543ES

Primary Objective
1.To estimate the site-specific IR of
P. falciparum infection by rapid
diagnostic test (RDT) testing,
overall and by age group (5-11
years, 12-17 years, 18-60 years)
during the active detection of
infection period.
Secondary objectives
1.To evaluate the agreement
between RDT and thick blood
smear (TBS), and to evaluate the
sensitivity and specificity of RDT
and TBS using quantitative
polymerase chain reaction (qPCR)
as the gold standard for the
identification of P. falciparum
infection, at baseline and at two
and six months after enrolment.
2.To estimate the site-specific IR of
P. falciparum infections detected
by both active and passive
surveillance over the complete follow-up period (0-6 months),
overall and by age group (5-11
years, 12-17 years, 18-60 years).
Uganda 2025-02-20 17:55:11 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
RITAH KICONCO
ID: UNCST-2021-R013263
MOLECULAR CHARACTERIZATION OF ANGIOTENSIN CONVERTING ENZYME GENE POLYMORPHISMS AMONG TYPE 2 DIABETES MELLITUS NEPHROPATHY IN SOUTHWESTERN UGANDA
REFNo: HS5520ES

Objectives:

Main Objective
1. To characterize angiotensin-converting enzyme gene polymorphisms and determine their relationship with the biomarkers of nephropathy and metabolic indicators as well as explore the barriers and motivators to screening for nephropathy among individuals with type 2 diabetes mellitus living in southwestern Uganda.
Specific Objectives
1. To conduct a systematic review on the ACE I/D polymorphisms and the urine albumin-to-creatinine ratio as predictive markers of nephropathy among adult type 2 diabetes mellitus patients.
2. To establish the ACE alleles and genotypes present in the genome of patients with T2D at the MRRH in SW in Uganda.
3. To determine the association between ACE gene polymorphisms and nephropathy biomarkers among T2D patients at the MRRH in SW Uganda.
4. To determine the association between ACE gene polymorphisms and metabolic indicators among T2D patients at the MRRH in SW Uganda.
5. To explore the barriers and motivators to screening for nephropathy as a health-seeking behavior among T2D patients receiving healthcare at the DM clinic in MRRH in SW Uganda.
Uganda 2025-02-20 17:50:43 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
VINCENT MUBANGIZI
ID: UNCST-2024-R004232
RAMPS: REDUCING ALCOHOL PROBLEM DRINKING AND MALNUTRITION THROUGH INCOME-GENERATING PEER SUPPORT GROUPS
REFNo: HS5394ES

To document and evaluate the first peer support groups for men with alcohol problem drinking in Isingiro district
Uganda 2025-02-20 17:49:15 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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