Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Betty Mwesigwa
ID: UNCST-2020-R014667
 Sabin 003: A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate Safety, Tolerability, and Immune Responses of an Investigational Monovalent Chimpanzee Adenoviral-Vectored Sudan Ebolavirus Vaccine in Healthy Adults
REFNo: HS3628ES

To evaluate the safety and tolerability of cAd3-EBO S vaccine
 Uganda 2024-02-13 17:35:43 2027-02-13 Medical and Health Sciences Clinical Trial Non-degree Award
Friday Christopher
ID: UNCST-2023-R007260
 SUSTAINABLE LAND MANAGEMENT PRACTICES AND ENVIRONMENTAL PROTECTION IN KABALE DISTRICT, UGANDA
REFNo: SS2370ES

i. To examine the effect of agroforestry on environmental protection in Kabale district, Uganda. ii. To determine the influence of crop rotation on environmental protection in Kabale district, Uganda. iii. To assess the effect of trenches and check dams on environmental protection in Kabale district, Uganda. iv. To establish the influence of mulching on environmental protection in Kabale district, Uganda. v. To evaluate the effectiveness of government policies in promoting environmental protection in Kabale district, Uganda.
Uganda 2024-02-09 23:38:35 2027-02-09 Social Science and Humanities Non-Clinical Trial Degree Award
Josephine Nayiga
ID: UNCST-2023-R005839
 Addressing bioethical challenges in HIV research to inform the development of a training program at Makerere University
REFNo: HS3771ES

3. Identify the preferences of trainees regarding future training in bioethics and ascertain their perceived knowledge gaps related to research bioethics,2. Investigate the perspectives of senior investigators at IDI and faculty members at Makerere University based on their experiences, focusing on the ethical dilemmas encountered by trainees engaged in HIV research,1. Evaluate the existing level of awareness and knowledge concerning bioethical challenges in HIV research among current and former trainees at IDI and the School of Medicine, Makerere University,To understand the training needs in research bioethics for trainees in the area of HIV and co-infections, in order to inform the development of a training program at Makerere University,
 Uganda 2024-02-09 23:36:15 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David  Ejalu Livingstone
ID:
ART Adherence among HIV-positive virally unsuppressed adolescents and young people: feasibility, acceptability, and effectiveness of a community-based implementation strategy to optimise compliance with intensive adherence counselling in East-Central Uganda.
REFNo: HS3807ES

1. To determine the level of compliance to IAC and the associated factors among virally unsuppressed Adolescents and Young People living with HIV in East Central Uganda.
2. To explore individual and system-level barriers to and facilitators of compliance to intensive adherence counselling protocol for enhancing ART adherence among unsuppressed Adolescents and Young People living with HIV in East-central Uganda.
3. To design a multifaceted theory-informed community-based IAC Implementation Strategy to optimize adherence for enhancing VLS among unsuppressed AYP in East-central Uganda.
4. To Evaluate the feasibility, acceptability, and effectiveness of a multifaceted theory-informed community-based IAC Implementation Strategy to optimize adherence among unsuppressed AYP in East-central Uganda.

 Uganda 2024-02-09 23:35:00 2027-02-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
 Closing TB Gaps using patient-centered approaches to improve TB Screening, Diagnosis and Prevention among people living with HIV
REFNo: HS3664ES

To assess the performance of novel TB screening algorithms among children,
adolescents, and adults living with HIV and presenting for routine care across a network
of family centered HIV clinics in Uganda and other four sub-Saharan African countries as
compared to the current WHO recommended symptom-based screening strategy.
To compare new diagnostic strategies leveraging the evaluation of multiple specimens
(stool and oral swab Xpert Ultra, early morning urine LF-LAM, point-of-care ultrasound
(POCUS), and a design locked Xpert Host Response Test against a reference standard
(Xpert Ultra on spot and early morning respiratory specimens) to improve diagnostic yield.
To compare the proportion of PLHIV who initiate and complete TPT with 3HP or 6H within
the context of a patient centered differentiated service delivery model allowing selection
of TPT regimen and randomly allocating enhanced adherence support versus the
standard of care for TPT and adherence support.
To evaluate the cost-effectiveness of screening and diagnostic strategies as well as
comparative TPT regimens for the prevention of TB disease among children, adolescents
and adults living with HIV
 Uganda 2024-02-09 23:32:58 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Birungi
ID: UNCST-2023-R005605
 A Family centred approach to enhance lifestyle change and behavioural modification for prevention of cardiovascular diseases among adolescents and their families in Uganda (FaCe-D) study
REFNo: HS3682ES

Main Objective
1. 1. We aim to explore the knowledge on cardiovascular health including CVD risk, perceptions and attitudes of participants, providers and other stakeholders towards the ihealth-T2D family-centered approach (FCA) as an intervention, obtain their input in the modification and design of the intervention to make it appropriate for Ugandan context
Specific Objectives
1. To explore the knowledge on cardiovascular health, perceptions, preferences and recommendations from potential participants on the proposed family-centered approach as an intervention for reducing and controlling common CVD risk factors among adolescents and their families.
2. To identify potential facilitators and barriers to adapting and implementing the FCA intervention in Uganda.
3. To use the data generated to design implementation strategies to promote the delivery, and uptake of the adapted FCA
 Uganda 2024-02-09 23:29:31 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nsobya  Samuel
ID: UNCST-2021-R012265
 Characterizing artemisinin resistance in severe malaria (CHARISMA): SMAART sub-study in Uganda
REFNo: HS3161ES

1. To characterize and compare the ex vivo drug susceptibilities of P. falciparum isolates from patients with and without severe malaria.
2. To characterize and compare genomic features of P. falciparum isolates infecting patients with and without severe malaria.
3. To assess whether presence of artemisinin partial resistance is associated with poor clinical outcomes in severe malaria patients.
4. To assess whether prior receipt of antimalarials is associated with artemisinin partial resistance in severe malaria patients

 Uganda 2024-02-09 23:26:22 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Assessment of Feasibility, Acceptability and Effectiveness of Training Village Health teams On Household Air Pollution Using Teach BOX
REFNo: HS3723ES

1. To assess the feasibility and acceptability of training Village Health Teams on Household Air Pollution using TeachBox in Jinja district Uganda.
2. To assess the effectiveness of training Village Health Teams on Household Air Pollution using TeachBox in Jinja district Uganda
 Uganda 2024-02-09 23:25:22 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Olupot-Olupot Olupot
ID: UNCST-2020-R014798
 DEVELOPMENT OF GEOSPATIO-TEMPORAL SURVEILLANCE AND CHARACTERISATION OF MALARIA IN THE CHANGING CLIMATIC CONDITIONS IN EASTERN UGANDA STUDY (GTS-MACS)
REFNo: HS3725ES

To determine the day three-parasite clearance rates of AL in children treated for malaria in Eastern and Northeastern Uganda. ,To determine whether there are any antimalarial drug resistance markers in Eastern and Northeastern Uganda. ,To describe geospatial-temporal patterns, determinants, and distribution of malaria with temperature, rainfall, and humidity patterns. ,Through geospatial-temporal surveillance, molecular studies and malaria parasite clearance rates, we shall characterise the overall epidemiology of malaria, any emergence of drug resistance and tolerance to the current antimalarials, respectively, in the era of changing climatic conditions in Eastern and Northeastern Uganda.,
 Uganda 2024-02-07 15:13:15 2027-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tonny Muzaale
ID: UNCST-2023-R006443
 Tracer Study of Graduates with Disabilities: A Case of 2010-2020 PLE Candidates
REFNo: SS2196ES

iii. To establish the views of graduates with disability on the relevance of training, skills and competences for the type of work they are doing and corresponding gaps to be filled in future. ,ii. To find out whether the graduates of 2010 PLE and the proceeding years are gainfully employed indicating the location/organizations. ,i. To examine the retrospective views of the students with disabilities based on their career experiences ,
 Uganda 2024-02-06 16:52:25 2027-02-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Businge Alinaitwe
ID:
Effectiveness of a Family-Centered Support Intervention on Treatment Adherence Among Tuberculosis Patients in Jinja, Uganda
REFNo: HS3583ES

General Objective To determine the effectiveness of a family-centered support TB (FaCeTB) intervention in improving adherence to TB treatment among patients receiving care from treatment centers in Jinja district, Eastern Uganda., Specific objectives To explore perspectives of patients, family caregivers and health care providers regarding involvement of family members in TB treatment adherence To determine the level of family support received by TB patients in Jinja district, Eastern Uganda. To evaluate the effect of the FaCeTB intervention on the level of TB treatment adherence among patients in Jinja district, Eastern Uganda. To examine the level of treatment adherence among patients before the implementation of a family-centered support TB (FaCeTB) intervention in Jinja district, Eastern Uganda.
Uganda 2024-02-06 16:51:27 2027-02-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Daniel Hill
ID:
Inclusive Coffee Value Chains – understanding coffee grower preferences and participation in specialty and commodity coffee value chains in the Kapchorwa District, Uganda.
REFNo: SS2312ES

To identify and measure coffee farmer preferences and participation in specialty and commodity coffee value chain in the Kapchorwa District, Uganda, to identify whether value chains are inclusive, identify how to improve inclusion of these value chains, and identify how farmers can derive more value from inclusion.
Australia 2024-02-06 16:48:36 2027-02-06 Social Science and Humanities Non-Clinical Trial Degree Award
Jonathan Mayito
ID: UNCST-2019-R000490
 Combatting Antimicrobial Resistance in Uganda: A Data-Driven Approach to Optimize Antibiotic Use and Improve Patient Outcomes
REFNo: HS3690ES

To estimate the annual economic burden of AMR in Uganda using the cost-of-illness approach,To use Machine Learning Algorithms to develop predictive models for clinical outcomes of patients with infectious syndromes due to resistant pathogens,To evaluate the trends in antibiotic use using annual antibiotic and point prevalence survey data collected at nine RRHs over a five year period,To build a dynamic AMR/AMUC Data Warehouse to support research in AMR and AMUC to inform AMR related interventions and public health policy ,
 Uganda 2024-02-06 16:46:26 2027-02-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Judith Arinaitwe
ID:
Exploring the Impact of Practices in Human Resource Development and Information Technology Use on Academic Staff performance in Bishop Stuart University
REFNo: SS2296ES

To examine how the interactions between practices in human resource development, information technology use, and academic staff performance at Bishop Stuart University shape overall performance outcomes.,To examine the utilization and integration of information technology (IT) tools and systems among academic staff at Bishop Stuart University.,To assess the current state of practices in human resource development (HRD) among academic staff at Bishop Stuart University.,The purpose of the study is to explore the impact of practices in human resource development and information technology use on academic staff performance at Bishop Stuart University.,
 Uganda 2024-02-06 16:45:37 2027-02-06 Social Science and Humanities Non-Clinical Trial Degree Award
Simon Peter Kibira
ID: UNCST-2020-R014668
 Advancing Understanding and Measurement of Infertility and Related Fear and Stigma in Uganda
REFNo: HS3624ES

Improve population-level infertility prevalence estimation by evaluating infertility measurement model assumptions in Uganda. (this was implemented as part of the PMA 2022 survey),Identify dimensions of infertility stigma and fear among women in Uganda.,Understand Ugandan women’s and men’s perceptions, fears, and experiences of infertility and its related stigma,to address these knowledge gaps by improving the field’s understanding of infertility levels, stigma, and fears in Uganda and sub Saharan Africa,
 Uganda 2024-02-06 16:44:24 2027-02-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MIRIA NYANGOMA
ID:
PROCUREMENT RISK MANAGEMENT AND LOCAL GOVERNMENT PERFORMANCE IN UGANDA:A CASE STUDY OF KANUNGU DISTRICT LOCAL GOVERNMENT
REFNo: SS2317ES

To establish the relationship between procurement risk treatment decision and performance of Kanungu District Local Government,To assess the relationship procurement risk monitoring and Performance of Kanungu District Local Government,To analyze the effect procurement risk assessment on Performance of Kanungu District Local Government,To examine the influence of procurement risk identification on performance of Kanungu District Local Government,To examine the relationship between procurement risk management and Local Government performance in Uganda,
 Uganda 2024-02-06 16:41:06 2027-02-06 Social Science and Humanities Non-Clinical Trial Degree Award
Tonny Muzaale
ID: UNCST-2023-R006443
 Psychometric properties analysis of UACE Biology 2022, 2020, 2018, 2015 and 2014: focus on item difficulty, distractor effectiveness and discrimination indices.
REFNo: SS2275ES

iii. To examine the difference between the distractor efficiency of the UACE Biology examination items of 2022, 2020, 2018, 2015 and 2014,ii. To examine the difference between the index of discriminating power of the UACE Biology examination items of 2022, 2020, 2018, 2015 and 2014,i. To examine the difference between the difficulty indices of the UACE Biology examination items of 2022, 2020, 2018, 2015 and 2014,
 Uganda 2024-02-06 16:39:21 2027-02-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Tonny Muzaale
ID: UNCST-2023-R006443
 Implementation of the New Competence-Based Curriculum in Lower Secondary School on Pre-Vocational Education in Uganda: Focus on School Readiness.
REFNo: SS2278ES

iii. To explore the challenges experienced in the implementation of the competency-based teaching and learning by both teachers and students. ,ii. To examine the assessment approaches under the competence-based teaching and learning of the new Lower Secondary Curriculum. ,i. To assess the understanding of competence-based teaching and learning of the new Lower Secondary Curriculum by teachers and students. ,
 Uganda 2024-02-06 16:34:04 2027-02-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Tonny Muzaale
ID: UNCST-2023-R006443
 Prevalence of Examination Malpractice at Uganda Certificate of Education: Challenges and Legal Implications
REFNo: SS2268ES

iii. To state the legal implications of examination malpractices and best practices for the enforcement of new UNEB Act 2021,ii. To examine the challenges faced by the examining body in curbing the vice in Uganda at UCE,i. To examine the extent to which examination malpractice prevails at UCE in Uganda,
 Uganda 2024-02-06 16:31:57 2027-02-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sandrine Perrot
ID: UNCST-2019-R001546
 The Bureaucratisation of Legal Identities in colonial and post-colonial Uganda: A Socio-History of State Registration and Documentation of Individuals
REFNo: SS2227ES

My main objective is to generate original insights on the construction of bureaucratic knowledge and techniques of identification and their impact on state construction and practices of citizenship in Uganda. Our goal is to
1. Identify the (un)favourable contexts for the introduction of identification policies
2. Map the players involved in identification over time
3. Highlight the changes in the instruments of identification
4. Examine the circulation of these practices
5. Observe the impact of state identification and registration on the practices of citizenship and the relation to the state
At this stage of my research, I would like to focus on three non-exclusive lines of enquiry: the debate surrounding the first identity cards during late colonialism; the documentation of non-indigenous people, and in particular the citizenship crisis of Asians in the 1960s and 1970s; and finally, the intense periods of identification during electoral periods, and more specifically the processes of voter registration.

France 2024-02-05 13:28:32 2027-02-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
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