Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Samalie Namukose
ID: UNCST-2022-R009222
Implementation of Multiple Micronutrient Supplementation for Pregnant Women in Uganda
REFNo: HS3070ES

3. To inform development of an implementation research study (e.g., define key research questions and inform implementation strategy development) that will inform effective introduction and scaling of MMS in Uganda,2. To assess the MMS demand drivers among pregnant women in Uganda,1. To map the context and extent of readiness for implementing an MMS intervention as part of antenatal care services in Uganda,
Uganda 2023-10-31 20:06:09 2026-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
Multi-level intervention for intersectional stigma reduction to improve HIV outcomes
REFNo: HS2977ES

Adapt the multilevel PRISM ISD-reduction intervention to address ISD for TGW in Uganda.

We will use the ADAPT-ITT model to adapt the multilevel PRISM intervention; specifically, the health facility TFA and individual-level ISD-reduction interventions (multilevel Ssinga nze intervention). Formative research (6 focus group discussions) with healthcare facility (HCF) staff and TGW at four health facilities ranked lowest on the PEPFAR Uganda stigma scorecard will explore ISD drivers and manifestations. We will use ADAPT-ITT to modify the multilevel Ssinga nze intervention comprising the HP+/HIVE3 interventions in consultation with community partners, peers, and providers. We will evaluate the feasibility and acceptability of the adapted Ssinga nze intervention using pre-post surveys, observation of trainings, and pre-post changes in mean scores on stigma scales.

Aim 2: Conduct a pilot hybrid type 1 effectiveness-implementation trial to test the preliminary effectiveness of the adapted multilevel Ssinga nze ISD-reduction intervention on (a) PrEP adherence or (b) viral suppression among TGW using a status-neutral approach.

Two of the health facilities in Aim 1 will be randomly assigned to Ssinga nze (the adapted HP+/HIVE3 intervention) with a 6-month wait-list control. TGW (N=120) will be randomly assigned to receive either Ssinga nze or wait-list control. All will enroll at study clinics, receive HIV testing, and be offered ART or PrEP depending on HIV status. TGW assigned to Ssinga nze will be followed at HIV clinics randomized to HP+; those assigned to wait-list control will attend control health facilities.

Aim 3: Evaluate implementation of Ssinga nze using qualitative methods.
Guided by the Intersectionality-Enhanced Consolidated Framework for Implementation Research [1], we will conduct in-depth interviews with purposively selected cadres of clinic staff trained in HP+ delivery (n=15) and TGW receiving HIVE3 (n=15), and 12 field observations (4 per clinic) to clarify how ISD-reduction intervention delivery may influence HIV prevention and treatment and to understand the actions and synergies of intervention components, assess health facility stigma reduction at HIV clinics for TGW, and interpret implementation data from Aim 2.

Uganda 2023-10-31 20:01:21 2026-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Adyanga Adyanga
ID:
Examining the relocation of the Batwa Indigenous people from the forests and its influence on their Indigenous Education, Customs and Cultures
REFNo: SS2097ES

Determine models for integrating indigenous education system and formal education system that built community/schools capacity to enhance the transmission of Batwa customs and cultures in their current setting,Establish how the integration of the Batwa into the dominant cultures influenced their customs and cultures in their current setting;,Examine the Batwa indigenous pedagogy and its effectiveness in inculcating Batwa custom and culture in their current setting,
Uganda 2023-10-31 20:00:15 2026-10-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
Peer Delivered HIV/Syphilis Self-Testing with Assisted Partner Notification Services for Men who Have Sex with Men (MSM) in Uganda
REFNo: HS3021ES

Estimate the cost-effectiveness of peer-delivered HIV/syphilis self-tests and partner services compared to facility-based testing.,Conduct a pilot randomized trial to pilot test the preliminary effectiveness of peer delivered HIV/syphilis self-tests and partner services versus facility-based testing., Conduct formative research to inform implementation of peer delivered self-tests for HIV and syphilis with partner services for Ugandan MSM. ,
Uganda 2023-10-31 19:59:00 2026-10-31 Medical and Health Sciences Clinical Trial Non-degree Award
Sharon Mutesasira
ID:
ASSOCIATION BETWEEN TIME OF DELIVERY AND IMMEDIATE ADVERSE PERINATAL OUTCOMES AMONG NEONATES DELIVERED AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS3072ES

3. To determine the factors associated with immediate adverse perinatal outcomes among neonates delivered at Mbarara Regional Referral Hospital,2. To determine the association between the time of delivery and the immediate adverse perinatal outcomes among neonates delivered at Mbarara Regional Referral Hospital,1. To determine the proportion of neonates with immediate adverse perinatal outcomes during night time delivery and day time delivery at Mbarara Regional Referral Hospital,To determine the proportion of immediate adverse perinatal outcomes among neonates delivered at Mbarara Regional Referral Hospital by time of delivery, and the association between the time of delivery and the immediate adverse perinatal outcomes ,
Uganda 2023-10-31 19:57:54 2026-10-31 Medical and Health Sciences Non-Clinical Trial Degree Award
SAMUEL PULE
ID:
SUPPLY CHAIN INFORMATION MANAGEMENT AND SERVICE DELIVERY WITHIN GOVERNMENT HEALTH CENTRES IN KAMPALA METROPOLITAN AREA
REFNo: SS2094ES

To examine the moderating effect of the operating environment on the relationship between supply chain information management and service delivery within Government health centres in Kampala Metropolitan Area.,To evaluate the relationship between supply chain information flow and service delivery within Government health centres in Kampala Metropolitan Area.,To assess the relationship between supply chain information storage and service delivery within Government health centres in Kampala Metropolitan Area.,To examine the relationship between supply chain information processing and service delivery within Government health centres in Kampala Metropolitan Area.,To examine the relationship between supply chain information management and service delivery within Government health centres in Kampala Metropolitan Area.,
Uganda 2023-10-31 19:54:54 2026-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
WALTER ORECH
ID: UNCST-2023-R007668
FUNGAL AND AFLATOXIN CONTAMINATION LEVELS OF HERBAL MEDICINE SOLD IN LIRA AND GULU CITIES, NORTHERN UGANDA
REFNo: NS640ES

The study aims to assess the fungal and aflatoxin contamination levels of herbal medicine consumed in Northern Uganda. ,To identify the fungal species in the herbal medicine sold in Lira and Gulu cities.,To ascertain the health risk associated with the consumption of herbal products.,To determine the level of aflatoxin in herbal medicines sold in Lira and Gulu cities.,
Uganda 2023-10-31 19:51:22 2026-10-31 Natural Sciences Non-Clinical Trial Degree Award
ANNE KAPAATA
ID: UNCST-2023-R007133
HIV-1 Genetic Diversity and Drug Resistance Mutations among Pregnant Women and Breastfeeding Mothers in Uganda
REFNo: HS3118ES

Overall Objective:
To describe HIV-1 Genetic Diversity and Drug Resistance Mutations among Pregnant Women and Breastfeeding Mothers in Uganda
Specific Objectives
1. To estimate the prevalence of HIVDRM and antiretroviral drug resistance profiles among Pregnant women and breastfeeding mothers with viral load non-suppression
2. To describe the circulating HIV-1 subtypes among pregnant women and breastfeeding mothers
with viral load non-suppression

Uganda 2023-10-31 19:49:58 2026-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Ojulong
ID: UNCST-2020-R014956
FACILITATING ACCESS TO ONLINE CONTENT IN SELECTED HIGHER INSTITUTIONS OF LEARNING: THE ROLE OF RENU AND NITA-U
REFNo: SS1961ES

1. To establish services available for facilitating access to online content in selected Higher Institutions of Learning in Uganda. 2. To establish the nature of services and technologies for facilitating access to online content in selected Higher Institutions of Learning in Uganda. 3. To examine the role of RENU and NITA-U in facilitating the availability of recommended services and mitigating the digital divide challenge related to access to online content in selected Higher Institutions of Learning in Uganda.
Uganda 2023-10-31 19:48:00 2026-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
Arthur Tabula
ID:
NUTRITIONAL VALUE AND ANTI-DIABETIC PROPERTIES OF THE AFRICAN OLIVE (Canarium schweinfurthii Engl.) FRUIT PULP
REFNo: A347ES

To investigate the cytotoxicity of C.schweinfurthii fruit pulp extract and its efficacy against diabetes in an alloxan-induced diabetes rat model. ,To determine the effect of C.schweinfurthii Engl. fruit pulp extract on alpha amylase activity and GLUT 4 translocation assays. ,. To identify and quantify the different polyphenolic compounds present in the fruit pulp.,To determine the proximate-, mineral-, fatty acid-, amino acid- and vitamin composition of the C.schweinfurthii Engl. fruit pulp.,To document the indigenous knowledge and practices on the use of C.schweinfurthii Engl. plant,To evaluate the chemical composition and anti-diabetic properties of Canarium schweinfurthii Engl. fruit pulp.,
Uganda 2023-10-31 19:44:44 2026-10-31 Agricultural Sciences Non-Clinical Trial Degree Award
Henry Ddungu
ID: UNCST-2019-R000966
Study on the impact of molecular and pathological diagnostic testing in myeloid neoplasms and support of Uganda tumor board patient cancer care and management
REFNo: HS3142ES

To evaluate if pathologic intervention provided at the Uganda Cancer Institute lymphoma tumor board impacts patient care and management at the Uganda Cancer Institute by improving patient outcomes,
Uganda 2023-10-31 19:42:18 2026-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Denis TUSHABOMWE
ID:
The Impact Of Agricultural Markets Liberalisation On Gender Relations In Smallholder White Potato Value chains in Rubanda District, South-western Uganda. Ref. No.: MUSSS-2023-236
REFNo: SS1985ES

4. To explore the changes in financial benefits of males and females in White potato value chains. ,3. To examine the changes in gender power relations in the access to, control and management of productive resources between males and females in White potato value chains.,2. To analyse the changes in gender roles, patterns and degree of labour participation between males and females across various White Potato value chain nodes.,1. To determine the forms of value chains and practices that have emerged among White Potato farmers in Rubanda district. ,The principal objective of the study will be to investigate the impact of liberalisation of agricultural markets on gender relations in smallholder agricultural value chains in Uganda, focusing on White Potato value chains in Rubanda district. ,
Uganda 2023-10-31 19:37:29 2026-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
Hajira Birungi
ID:
ENTREPRENEURIAL ECOSYSTEM PILLARS AND PERFORMANCE OF SME’S IN THE MANUFACTURING SECTOR OF UGANDA
REFNo: SS1993ES

1 To investigate the relationship between institutional arrangements and performance of SMEs in the manufacturing sector of Uganda
2 To establish the relationship between resource endowments and performance of SMEs in the manufacturing sector of Uganda.
3 To find out the relationship between entrepreneurial ecosystem pillars and competitive advantage of SMEs in the manufacturing sector.
4 To examine the mediation effect of competitive advantage on entrepreneurial ecosystem pillars and performance of SMEs in the manufacturing sector of Uganda

Uganda 2023-10-31 19:35:59 2026-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
Helen   Mukakarisa Kataratambi
ID: UNCST-2022-R010556
Development and piloting of an intervention for teaching and learning of therapeutic communication among nursing students in Kampala, Uganda
REFNo: HS3180ES

4. To assess the effectiveness of the designed intervention for teaching and learning TC among diploma nursing students in Kampala ,3. To design and pilot an educational intervention for teaching and learning of TC among diploma nursing students in Kampala ,2. To determine factors associated with teaching and learning TC among diploma nursing students in Kampala ,1. To explore facilitators and barriers to teaching and learning TC among among diploma nursing students in Kampala ,
Uganda 2023-10-31 19:29:23 2026-10-31 Medical and Health Sciences Non-Clinical Trial Degree Award
Dorothy Massa
ID:
Understanding Congolese Refugee Women at Risk Experiences in Light of Social Protection Initiatives and Policy Interventions in Uganda
REFNo: SS2108ES

Research Objectives
Explore the lived experiences, perceptions, and needs of Congolese RWaR in Nakivale refugee settlement.

Specifically, the research seeks to:
i. Describe the types and sources of risks, including Gender-Based Violence experienced by RWaR in their everyday life.
ii. Identify the resilience strategies utilized by RWaR and measures needed to thrive through different adversities.
iii. Explain how social protection programs and policies by state and non-state actors are shaping the social welfare, dignity and quality of life of RWaR.
iv. Propose ways through which RWaR social welfare, dignity, and quality of life can be sustained amidst hardships by RWaR, state and non-state actors.

Uganda 2023-10-31 19:25:40 2026-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
Mary Nabacwa Ssonko
ID: UNCST-2023-R007407
The National Roll-out of the Care Policy Score in Uganda: A Contextualised Analysis of Uganda's Investment and Policy Actions on Care and Domestic Work
REFNo: SS2018ES

Identify opportunities towards policy influencing and action towards inclusion of Unpaid Care and Domestic work into national programmes and policy actions. ,Provide policy makers with evidence and Information to make informed decisions on these policies. ,Measure and track government progress and commitments systematically and holistically across public policy areas for unpaid care and domestic work. ,Assess, quantify and track the extent to which government policies related to care are adopted, budgeted for and implemented, and the extent to which they have a transformative effect on care and domestic work,
Uganda 2023-10-30 21:20:45 2026-10-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
Rapid ethnographic assessment of study sites for a future trial of oral (on-demand and daily) and long-acting Pre-exposure prophylaxis for mobile men in South Africa and Uganda
REFNo: HS3099ES

a) Provide an overview for each site of the population characteristics, paying particular
attention to men who are mobile for work.
b) Describe the perceptions of sexual health risks for both men and women held by members
of the community.
c) Document the HIV prevention options available at each site and give some preliminary insights into men’s attitudes towards and use of those options.
d) Identify opportunities and settings to create demand and deliver biomedical HIV
prevention including PrEP (oral and injectable) for mobile men.
Uganda 2023-10-30 21:18:58 2026-10-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Henriettah Nakisozi
ID:
FUNCTIONAL CHARACTERISTICS OF BIOACTIVE COMPOUNDS FROM BYPRODUCTS OF MANGO (Mangifera Indica)
REFNo: A367ES

5. To determine the quality characteristics (lipid oxidation value, carbonyl content, thiol content, pH, cooking properties, color, total volatile nitrogen, moisture, protein, lipid, ash and carbohydrate contents) beef sausages containing mango peel, kernel and seed extracts.,4. To determine amounts of predominant bioactive compounds in pulp, peel, seed and kernel ripe mango varieties after solar drying, force air oven drying and freeze drying.,3. To quantify bioactive compounds (phenolic compounds, flavonoids, phenolic acids, carotenoids, anthocyanins, phytosterols, ascorbic acid, vitamin E) from fresh pulp, peel, kernel and seed of ripe mango varieties grown in Uganda.,2. To determine the physicochemical properties (moisture content, ash content, carbohydrate content, protein content, fibre content, fat content, mineral content, titratable acidity, pH, total soluble solids (TSS), tannins, oxalates) of pulp, peel, kernel and seed of ripe mango varieties.,1. To determine morphometric characteristics (fruit size, fruit weight, fruit colour, volume, pulp texture, pulp firmness, peel thickness) of mature mango varieties grown in Uganda,To evaluate the functional characteristics of bioactive compounds from byproducts of mango produced in Uganda.,
Uganda 2023-10-30 21:17:54 2026-10-30 Agricultural Sciences Non-Clinical Trial Degree Award
David Kyaddondo
ID: UNCST-2020-R014906
Factors Associated with Continuity of Care among Forcibly Displaced Persons with Hypertension and/or Type 2 Diabetes in Bidi Bidi Refugee Settlement in Uganda
REFNo: SS1959ES


Main objective

To investigate factors affecting access to and (dis)continuity of HTN and/or type 2 diabetes care among FDPs in the Bidibidi refugee settlement, Uganda

Specific Objectives

1.To determine the sociodemographic and health-related characteristics of FDPs with HTN and/or type 2 diabetes.

2.To estimate awareness, treatment, and attainment of HTN and/or type 2 diabetes control among FDPs.

3.To investigate the association between mobility-related factors and (dis)continuity of care among FDPs with HTN and/or type 2 diabetes.

4.To investigate the association between social factors and (dis)continuity of care among FDPs with HTN and/or type 2 diabetes.

5.To explore the effects and consequences of mobility on the control of HTN and/or type 2 diabetes in FDPs.

6.To explore stakeholders’ and FDPs’ perception of the (dis)continuity of care for HTN and/or type 2 diabetes.

Uganda 2023-10-30 21:16:31 2026-10-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
MUTEKANGA ANDREW
ID:
VITAMIN B12 DEFICIENCY AND ITS CORRELATION WITH PERIPHERAL NEUROPATHY AND COGNITIVE DYSFUNCTION IN DIABETES AT TWO PRIMARY HEALTHCARE LEVEL IN SOUTHWESTERN UGANDA
REFNo: HS3178ES

To determine the prevalence of vitamin B12 deficiency and its associations with peripheral neuropathy and impaired cognitive function, among people living diabetes in primary healthcare settings in southwest Uganda
Uganda 2023-10-30 21:14:05 2026-10-30 Medical and Health Sciences Non-Clinical Trial Degree Award
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