Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Damari Atusasiire
ID: UNCST-2024-R002645
Evaluation of the One Acre Fund project - making 34,000 coffee farmers more resilient by 2027
REFNo: A560ES

To establish whether all household members are equally benefiting from the impacts of the project and how? ,To determine which pursued pathways of change are the main drivers in delivering outcome and impact? ,To establish the causal effects of the project for direct project participants? ,
Uganda 2025-02-07 18:04:15 2028-02-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Michelle Brown
ID: UNCST-2022-R009670
Describing the vocal repertoire of L’Hoest’s monkeys
REFNo: NS410ES

To test whether L’Hoest’s monkeys (Allochrocebus lhoesti) contradict the ‘social complexity hypothesis’ by determining whether they communicate in frequencies too low for human hearing.
USA 2025-02-07 18:02:59 2028-02-07 Natural Sciences Non-Clinical Trial Non-degree Award
Damari Atusasiire
ID: UNCST-2024-R002645
Incidence and economic impacts of bovine mastitis in smallholder dairy farms in Kenya and Uganda
REFNo: A564ES

To assess knowledge of bovine mastitis, its control and treatment among smallholder dairy farmers.
To assess the effectiveness of using cell phone technology as a method of disseminating information on udder health to farmers.
To estimate the incidence rate of clinical and subclinical mastitis among recently-calved dairy cows (≤4 weeks prior to baseline data collection).
To determine the drivers of bovine mastitis among sampled dairy cows.
To estimate the monthly and annual financial losses attributed to clinical and subclinical mastitis.
Uganda 2025-02-07 18:01:56 2028-02-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
Assessment of the functionality of health unit management committees in primary healthcare health facilities in Uganda: a case of health center IIIs
REFNo: HS5407ES

a) To determine the presence and functionality of HUMCs in HCIIIs
b) To determine the factors influencing the functionality status of HUMCs in HCIIIs
c) To identify any interventions needed to strengthen the performance of HUMCs in HCIIIs.

Uganda 2025-02-07 17:59:08 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
Factors influencing the Functionality of Medicines and Therapeutic Committees in Public Health Facilities in Uganda: A Longitudinal Assessment
REFNo: HS5391ES

a) Provide the current functionality of MTCs in public HFs
b) Determine the factors associated with the functionality of MTCs in public HFs

Uganda 2025-02-07 17:56:57 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve Nakabembe
ID: UNCST-2024-R015226
PReparing for OptimalPhase III/IV maTErnal Group B StreptococCal vaccine Trials in Africa
REFNo: HS5463ES

1. To generate longitudinal cohort data on pregnancies, deliveries and infant outcomes for maternal Group B Streptococcus vaccine safety assessment
2. To develop and strengthen capacities for Group B Streptococcus disease surveillance in infants less than 90 days old at Kawempe National Referral Hospital, using microbiological and molecular detection methods.
3. To explore the perceptions of pregnant women, health care providers, community members and other relevant stakeholders about the barriers and drivers for pregnant women to participate in Group B Streptococcus vaccine trials.
4. To co-create a communication/education toolkit to enhance understanding of the importance of maternal Group B Streptococcus vaccine trials and improve enrolment of pregnant women in vaccine trials in Uganda.

Uganda 2025-02-07 17:52:29 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tonny Okecha
ID: UNCST-2022-R011105
CLINICOPATHOLOGICAL AND MOLECULAR PROFILE OF MALE BREAST CANCER AT THE UGANDA CANCER INSTITUTE
REFNo: HS5435ES

2. To describe the mutational profile of male breast cancer at the Uganda Cancer Institute.,1. To describe the clinico-pathological features of male breast cancer at the Uganda Cancer Institute,To describe the clinicopathological and molecular profile of male breast cancer at the Uganda Cancer Institute.,
Uganda 2025-02-07 17:49:22 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrea Spray Lynn
ID: UNCST-2023-R007304
Maternal mental health and early childhood development in Kawempe
REFNo: HS5448ES

PRIMARY: To assess the associations between symptoms of common MMH conditions (depression and anxiety) and child care practices and outcomes (physical growth and ECD) in the Kawempe Division of Kampala, Uganda.
SECONDARY: To assess the associations between symptoms of common MMH conditions (depression and anxiety) and underlying individual, interpersonal, and household factors.
SECONDARY: To explore what "mental health" means to mothers of children under two years of age currently living in Kawempe, how their mental health effects their daily life; the activities they do that contribute to "good" and "bad" mental health.
TERTIARY / EXPLORATORY: To determine the prevalence of common MMH conditions (depression and anxiety) in the KYC catchment area.
TERTIARY / EXPLORATORY: To create Luganda versions of the CREDI, GSED, RSES, PSS, and CFAT.
TERTIARY / EXPLORATORY: To compare the CREDI and GSED tools for measuring ECD in this context.
USA 2025-02-07 17:47:50 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MIRIAH KEMIGISHA
ID: UNCST-2022-R009927
Evaluating Ventricle Size and Shunt Failure Rates in Ugandan Children Shunted Early in Life
REFNo: HS5382ES

General objective
To study proximal shunt obstruction and its predictors among patients with hydrocephalus secondary to myelomeningocele or encephalocele at CCHU from 2010 to 2023.

Specific Objectives.

1.To determine the rate of proximal obstruction among shunted patients with hydrocephalus secondary to myelomeningocele or encephalocele.
2.To determine the incidence of small ventricles among shunted patients with hydrocephalus following myelomeningocele or encephalocele closure.
3.To assess if ventricle size and catheter environment can predict proximal shunt failure in shunted patients with hydrocephalus secondary to myelomeningocele or encephalocele.

Uganda 2025-02-07 17:46:28 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOYCE NAMWASE
ID: UNCST-2024-R005002
ACCEPTABILITY, FEASIBILITY AND EFFECTIVENESS OF INVOLVING LAY HEALTH WORKERS IN RECOGNIZING AND LINKING PEOPLE WITH ALCOHOL USE DISORDER TO PRIMARY HEALTH CARE PROVIDERS
REFNo: HS5364ES

1.
To explore the perceived capability, opportunities, and motivation of LHWs to identify AUD in Ibanda district, southwestern Uganda.
2.
To implement a strategy of training lay health workers in the use of CAGE screening tool to identify AUD in Ibanda district, southwestern Uganda.
3.
To evaluate the acceptability, appropriateness, and feasibility of involving LHWs in screening for AUD in the community of Ibanda district, southwestern Uganda
Uganda 2025-02-07 17:44:48 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
UBUMWE 2.0 Integrating Arts for Education and Psychosocial Support with Children & Youth affected by Displacement in Uganda
REFNo: SS3567ES

1. To document how the Ubumwe curriculum influenced the roles and responsibilities of the teachers;
2. To identify additional teacher professional development opportunities that teachers feel are needed to be successful in teaching the Arts;
3. To explore the ways in which the art curriculum impacted Learners’ academic and psychosocial development;
4. To assess overall feasibility, acceptability, strengths and limitations of the Ubumwe curriculum for teachers.

Uganda 2025-02-07 17:43:07 2028-02-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
Factors influencing the availability and use of Electronic Medical Records Systems in Public Health Facilities in Uganda: A landscape assessment
REFNo: HS5379ES

i. Assess the extent of EMR adoption in public health facilities.
ii. Identify the types of EMR systems currently in use.
iii. Evaluate the functionality and integration of existing EMR systems.
iv. Understand the challenges and barriers to effective implementation of EMR integration.
v. Identify the factors influencing the use and adoption of EMR systems in public health facilities.
vi. Provide recommendations for enhancing EMR adoption and utilization.

Uganda 2025-02-07 17:42:08 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Prossy Bibangambah Kyasimire
ID: UNCST-2024-R002215
Pericoronary Adipose Tissue, Inflammation, and Subclinical Coronary Artery Disease in People with HIV in Uganda
REFNo: HS5418ES

Aim 1: Perform CCTA -based segmentation of PCAT (1a) and compare the density between PWH and PWOH (1b) in Uganda.
Aim 2: Extract PCAT radiomics features (2a) and compare differences in PCAT radiomics signatures between PWH and PWOH (2b) in Uganda.
Aim 3: Determine whether the PCAT density (from Aim 1) or radiomics signatures (from Aim 2) improve the performance of cardiovascular risk prediction in Uganda.
Uganda 2025-02-07 17:38:35 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
Bone Health in Older Ugandan Women with and without HIV
REFNo: HS5455ES

To examine bone mineral density (BMD) and body composition in older (peri-menopausal and postmenopausal) African women who are living with HIV and taking antiretroviral therapy (ART) drugs compared to women representing similar age and background characteristics who are HIV-negative.
Uganda 2025-02-07 17:30:13 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jennifer Serwanga
ID: UNCST-2024-R002056
Universal Protocol for Standardizing emerging Assays and Advancing vaccine Immunogenicity Assessments for Emerging and Re-emerging viral Threats through UVRI’S Partnership with the coalition for Epidemic Preparedness Innovations (CEPI)’s Centralized Clinical Laboratory Network (CLN).
REFNo: HS5330ES

To standardize and accelerate the evaluation of vaccine candidates against CEPI priority diseases, including Ebola, Marburg, Lassa, Nipah, Rift Valley Fever, SARS-CoV-2, MPOX and unidentified emerging threats, by leveraging UVRI's infrastructure and expertise.

To contribute to accelerated global vaccine development and licensure by ensuring rapid, accurate, and consistent data generation, while enhancing regional outbreak preparedness through technology transfer and capacity building.
Uganda 2025-02-04 8:15:09 2028-02-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald  Bahati
ID: UNCST-2023-R007024
NAVIGATING MENTAL HEALTH IN SCHOOLS PROJECT: EDUCATORS’ MENTAL HEALTH LITERACY CONCERNING ANXIETY, DEPRESSION AND NON-SUICIDAL SELF INJURY
REFNo: HS5381ES

To ascertain the educators’ confidence in providing help to affected school aged adolescents in selected schools in southwestern Uganda.,3. To assess educators’ level of mental health literacy about non-suicidal self-injury among school aged adolescents in selected schools in southwestern Uganda.,2. To assess educators’ level of mental health literacy about depression among school aged adolescents in selected schools in southwestern Uganda,1. To assess educators’ level of mental health literacy about anxiety among school aged adolescents in selected schools in southwestern Uganda,To assess educator’s mental health literacy about anxiety, depression and non-suicidal self-injury and their confidence in providing help to affected school aged adolescents in selected schools in southwestern Uganda.,
Uganda 2025-01-31 8:00:54 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Shevin  Jacob Thomas
ID: UNCST-2022-R010715
The Sub-Saharan Africa ConsorTium for the Advancement of Innovative Research and Care in Sepsis (STAIRS) Cohort Study: A prospective multi-country network cohort of hospitalized sepsis patients
REFNo: HS5205ES

1. Describe the cohort’s epidemiologic, sociodemographic, clinical and management characteristics and to identify risk factors for disease severity and outcomes. 2. Characterize etiologic (and antimicrobial resistance patterns when relevant) and host response profiles and to evaluate their potential associations with clinical presentation, disease severity and outcome. 3. Determine the performance characteristics of innovative sepsis diagnostic platforms for pathogen identification, host response profiling and risk stratification in comparison with diagnostic testing available for usual care (including blood culture and existing sepsis scores).
USA 2025-01-31 7:59:00 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sabiti Makara
ID: UNCST-2024-R003444
Crisis Emergencies, State Responses and ‘Windows’ of Corruption in Uganda
REFNo: SS3621ES

To implement bottom-up strategies for fighting corruption in emergency responses ,To examine the possibilities of grassroots actions and pressures that could have significant impacts on the fight against corruption,To establish the extent to which political considerations abate corruption with a focus on procurement and contracting during emergency crisis responses,To establish the gaps in regulatory frameworks that are opportunistically exploited by corrupt officials and their cronies to undermine anti-corruption efforts during emergency responses,Establish the actual costs of corruption and find out if the population is aware of its effects on public service delivery for the ordinary citizens,To examine the forms, practices, and patterns of corruption in emergency crisis responses in Uganda,Our main objective is to highlight and deepen our understanding of the extent which the risk of corruption intensifies during emergencies and to develop grassroots-based strategies to fight the vice.,
Uganda 2025-01-31 7:50:39 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Vincent Ferrer Bukenya
ID: UNCST-2024-R004868
Examination of the relationships between refugee settlements and wood energy consumption: A case study of Bidibidi refugee settlement in northwest Uganda
REFNo: A527ES

This research will examine the relationships between refugee settlements and household access to sustainable wood energy. 1. To establish what forms the bulk of wood energy used by refugees and host communities in Bidibidi Refugee Settlement in North-Western Uganda. 2. To assess wood energy consumption patterns in refugee and host communities in relation to the right to energy in Bidibidi Refugee Settlement in North-Western Uganda. 3. To examine how the refugee response framework provides for household access to wood energy by refugees and host communities in Bidibidi Refugee Settlement in North-Western Uganda. 4. To determine the contribution of the refuge-host community relationships to households’ ability to sustainably access wood energy.
Uganda 2025-01-31 7:43:24 2028-01-31 Agricultural Sciences Non-Clinical Trial Degree Award
Ikuomola  Orire Emmanuel
ID: UNCST-2024-R003700
EFFECT OF DIFFERENT FRACTIONS OF BRASSICA OLERACEA (COLLARD GREENS) ETHANOL EXTRACT ON CIMETIDINE INDUCED REPRODUCTIVE TOXICITY IN MALE WISTAR RATS.
REFNo: HS5192ES

i. Identify and quantify the constituents of crude aqueous leaf extract and fractions of Uganda collard green plant using gas chromatography mass spectrometry (GCMS);
ii. Evaluate the impact of crude aqueous leaf extract and fractions of Uganda collard greens on the relative weights of the testes, epididymis and anterior pituitary gland compared to body weight in male Wistar rats with cimetidine-induced reproductive toxicity by [specific date] male Wistar rats;
iii. Assess the effects of crude aqueous leaf extract and fractions of Uganda collard greens on sperm parameters, including motility, morphology, viability, agglutination, and total sperm count in Wistar rats with cimetidine-induced reproductive toxicity;
iv. Analyze the effect of crude aqueous leaf extract and fractions of Uganda collard greens on serum levels of steroid androgens (LH, FSH, Testosterone and antioxidant enzyme activities (catalase, Malondialdehyde, superoxide dismutase) in male Wistar rats with cimetidine-induced reproductive toxicity in male Wistar rats;
v. Examine the histological changes in the testes, epididymis, and anterior pituitary gland in male Wistar rats with cimetidine-induced reproductive toxicity following treatment with crude aqueous leaf extract and fractions of Uganda collard greens in male Wistar rats.

Nigeria 2025-01-31 7:40:27 2028-01-31 Medical and Health Sciences Non-Clinical Trial Degree Award
Miriam  Amutuheire
ID: UNCST-2024-R001859
Home-based tourism businesses and destinaion sustainability in Kabale Municiplaity, Kabale District, Uganda.
REFNo: SS3399ES

i.To assess the effect of the home-based tourism business operations on destination sustainability in Kabale municipality, Kabale District, Uganda.    
ii. To determine the influence of home-based tourism businesses competitiveness on destination sustainability in Kabale municipality, Kabale District, Uganda.  
iii. To establish the influence of government policies, impart on home-based tourism businesses that affect destination sustainability in Kabale municipality, Kabale District, Uganda.  
Uganda 2025-01-31 7:38:46 2028-01-31 Social Science and Humanities Non-Clinical Trial Degree Award
Karugahe Wilber
ID: UNCST-2023-R005686
Effectiveness of Cognitive behaviour therapy for mental health problems among adult patients with type-II diabetes mellitus: a controlled study
REFNo: SS3413ES

a. To assess the effectiveness of CBT in treating mental health problems (psychological distress, depression, anxiety, quality of life, treatment adherence, hopelessness, pessimism) among adult patients with T2DM
b. To assess whether CBT affords a better control of glycaemia and the metabolic disturbances associated with T2DM.

Uganda 2025-01-31 7:37:29 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
Maternal immunization readiness network for the introduction of potential new maternal vaccines to prevent early childhood infectious diseases in Uganda
REFNo: HS5271ES

General objective:

To identify, characterize and support the platform, policy, and preparedness requirements for the introduction of potential new maternal vaccines to prevent infectious diseases in Uganda


Specific objectives:

1. To identify and implement approaches to assess health systems, facilities, and community readiness to introduce new maternal vaccines in Uganda
a. Identify and implement approaches to assess MI readiness for respiratory syncytial virus / Group B streptococcus vaccinations across the health system, including mapping key regulatory and financing requirements.
b. Map professional societies within the country and initiate country-based communities of practice for MI.
2. Generate and synthesize health economic evidence, in the Ugandan context, to support decision-making of respiratory syncytial virus / Group B streptococcus vaccination program adoption in low- and middle-income countries (LMICs).
3. Prospectively develop nationally tailored maternal vaccine demand strategies to support the uptake and sustained demand for existing and new maternal vaccines in Uganda.
4. Identify and effectively engage with diverse stakeholders, in a harmonized manner, to incorporate their views and expertise in the study’s outputs, to advance the maternal immunization readiness agenda in Uganda.

Uganda 2025-01-31 7:35:56 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Rukundo NSHAKIRA
ID: UNCST-2021-R012277
Improving School Management in a Low-Income Country: Experimental Evidence from Uganda
REFNo: SS3462ES

To evaluate the impact of the Inspect and Improve (I&I) program on student outcomes (learning, safeguarding, and inclusion) and school quality, focusing on both short-term and long-term effects.
Uganda 2025-01-31 7:32:19 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moses Ochora
ID: UNCST-2021-R012659
RUNYA-PHIV: Rural Uganda Neurocognitive Youth Assessment with Perinatally acquired HIV
REFNo: HS5534ES

To explore the differences in NeuroScreen performance among adolescents aged 12-19 years with Perinatally acquired HIV in urban (Kampala) vs rural areas (Mbarara).,To adapt NeuroScreen to assess neurocognition among Runyankole-speaking adolescents aged 12-19 years with Perinatally Acquired HIV ,
Uganda 2025-01-31 7:31:16 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samuel Kyobe
ID: UNCST-2019-R000108
DSpace – Ethical Implications of Pediatric EHR Use in Medical Research in Uganda and Botswana
REFNo: HS5301ES

1. Analyze the ELP issues raised by the use of pediatric EHR in medical research in Uganda and Botswana
2. Determine/analyze the implications of data linkage on participant consent and privacy
Uganda 2025-01-31 7:27:19 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Maleka
ID: UNCST-2024-R015301
Sex differences in alcohol consumption and its impact on vulnerability and susceptibility to develop dementia in rural Uganda.
REFNo: SS3477ES

1. To determine the patterns of alcohol consumption among men and women aged 60 years and above in Ibanda and Lira districts.
2. To assess the association between alcohol consumption and cognitive impairment among men and women in rural Uganda
3. To determine the socio-cultural factors that contribute to gender differences in the vulnerability to alcohol-related cognitive impairment in Ibanda and Lira districts.

Uganda 2025-01-31 7:24:38 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
john semuwemba
ID: UNCST-2022-R015225
Association between prenatal alcohol exposure and Cognitive and Behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.
REFNo: HS5331ES

General Objective.
To determine the prevalence of prenatal alcohol exposure and the association between prenatal alcohol exposure and cognitive and behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.
Specific Objectives.
1 To determine the prevalence of prenatal alcohol exposure in rural Rwampara and Lira districts.
2 To determine the prevalence of cognitive and behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.
3 To determine the association between prenatal alcohol exposure and cognitive and behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.

Uganda 2025-01-31 7:22:50 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Mukunya
ID: UNCST-2022-R010707
A phase III, randomized, open-label, clinical trial to evaluate the safety and efficacy of emollient therapy for very low birthweight infants (<1500g) in Uganda in promoting survival, health, growth and development compared to no emollient treatment
REFNo: HS5338ES

To evaluate the efficacy of emollient therapy with SSO – compared to standard care without use of emollients – among hospitalised very low birth weight (VLBW, <1500g) infants in Uganda on: the rate of in-hospital mortality, serious infections, hypothermia, growth, intraventricular haemorrhage, and skin condition; maternal depression and anxiety; maternal and neonatal interaction; infant growth and neurodevelopment at 12 month corrected age (chronological age reduced by the number of weeks born before 40 weeks of gestation); and infant mortality.
Uganda 2025-01-31 7:21:53 2028-01-31 Medical and Health Sciences Clinical Trial Non-degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
Evidence based QUality Improvement for Prescribing Stewardship in ICU (EQUIPS-ICU): protocol for type III hybrid implementation-effectiveness study.
REFNo: HS5389ES

To evaluate the impact of a structured antimicrobial review on rates of antimicrobial density, redundancy and associated indicators of antimicrobial utilisation.,To determine whether a structured antimicrobial review can be implemented in LMIC ICUs,
UK 2025-01-31 7:20:18 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WAYENGERA Misaki
ID: UNCST-2024-R002503
DECIPHERING HOST GENETICS AND VIRAL DETERMINANTS OF MPOX PATHOGENESIS IN THE DEMOCRATIC REPUBLIC OF CONGO AND THE NEIGHBORING COUNTRIES (DECIPHER-MPOX)
REFNo: HS5409ES

The goal of the DECIPHER-MPOX project is to determine the host genetic and viral determinants of mpox in Uganda and in the Democratic Republic of Congo (DRC) among survivors of mpox and their house hold contacts ,
Uganda 2025-01-31 7:18:46 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jackson Tumwine Bwagiro
ID: UNCST-2024-R004504
Promotion of integrated and sustainable community interventions to prevent GBV and strengthen Adolescent Sexual Reproductive health and rights. A realistic evaluation protocal from Uganda
REFNo: SS3540ES

The overall objective is to promote integrated and sustainable community interventions to prevent GBV and Strengthen SRHR,
Uganda 2025-01-31 7:17:15 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Kanyike Marvin
ID: UNCST-2020-R014554
Optimizing Hypertension and Type 2 Diabetes Mellitus Management among People Living with HIV using a HEARTS-Based Strategy in Eastern Uganda: A Feasibility and Preliminary Effectiveness Study.
REFNo: HS5399ES

To identify the barriers and facilitators to the optimal management of HTN and T2DM among PLHIV at Mbale Regional Referral Hospital in Eastern Uganda.

To develop and implement a HEARTS-based strategy for optimized management of HTN and T2DM among PLHIV at Mbale Regional Referral Hospital in Eastern Uganda.

To determine the feasibility, acceptability, and preliminary effectiveness of the HEARTS-based strategy in optimizing the management of HTN and DM among PLHIV at the Mbale Regional Referral Hospital in Eastern Uganda.

To evaluate the reach, adoption, implementation, and maintenance of the HEARTS-based strategy for optimizing hypertension and diabetes mellitus management among PLHIV at Mbale Regional Referral Hospital.

Uganda 2025-01-31 7:16:22 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mordecai Tayebwa
ID: UNCST-2024-R002437
Expanded Strengthening of Makerere University's Research Administration Capacity Program (E-SMAC)
REFNo: HS5531ES

Test knowledge and skills change over time of faculty prior to and following the SOP trainings and implementation activities ,Test knowledge and skills change over time of participating RA staff prior to and following the SOP trainings and implementation activities ,Test knowledge and skills change over time of participating RA staff and faculty prior to and following the SOP trainings and implementation activities ,
Uganda 2025-01-30 18:30:42 2028-01-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
Evidence Synthesis To Inform Strengthening Medical Oxygen Systems in low- and middle-income countries”. (ESTISMOS)
REFNo: HS5437ES

10. To assess the implementation outcomes and impact of the Oxygen-as-a- service intervention in Uganda, Kenya, Tanzania, and Nigeria,9. To determine the health facility readiness, also known as “change valence”, to implement the Oxygen-as-a- service intervention in Uganda, Kenya, Tanzania, and Nigeria.,8. To assess the capability (real and perceived) of the selected health facilities, also known as, “change efficacy” to implement the Oxygen-as-a- service intervention in Uganda. ,7. To examine the coordination mechanisms at national, district, health facility levels that facilitate availability of medical oxygen at health facilities.,6. To examine the stakeholder positions, interests, and influences along the medical oxygen supply chain on access to medical oxygen at health facilities.,5. To characterize processes and tools for information flow and management for medical oxygen and oxygen related equipment.,4. To map the medical oxygen supply chain system and explore the nodes and links from the medical oxygen sources to health facilities where it is needed.,3. To synthesize the extent to which healthcare packages have incorporated oxygen therapy solutions to promote their adoption, scale up and sustainability. ,2. To summarize the implementation outcomes of oxygen therapy solutions from published intervention studies in LMICs. ,1. To synthesize determinants of implementation outcomes of oxygen therapy solutions in low- and middle-income countries.,
Uganda 2025-01-30 18:27:31 2028-01-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adityavarman Mehta Umesh
ID: UNCST-2024-R002841
The Role of Global Health Diplomacy in Achieving Peacebuilding in Post-Conflict Northern Uganda
REFNo: SS3590ES

In this context, the thesis will examine the use of global health diplomacy, which aims to bridge the disciplines of public health, international relations, and public policy, as a peacebuilding instrument in northern Uganda. With numerous health initiatives such as those that addressed the increasing incidence of HIV/AIDS and Ebola during the civil war between 1986 and 2006, and psychosocial programs following the conclusion of the war, there is scope to determine whether these health initiatives contributed to the cessation of violence and ultimately, peacebuilding. This thesis will arrive at this determination by assessing if health initiatives implemented in northern Uganda during and after the conflict fostered social cohesion and afforded Ugandans, particularly women, agency or the opportunities to follow through on their choices. The twenty-year conflict in northern Uganda provides an effective context for this thesis because the violence was largely a product of its political and social history (Kustenbauder, 2010). The violence had ethnic and religious dimensions as well, with academic literature on the subject suggesting that the largest rebel group fighting the national army, the Lord’s Resistance Army, viewed its struggle against the government of Uganda as a divine cause, which was guided by God through its leader, Joseph Kony (Van Acker, 2004). Against this political and historical backdrop, this thesis will aim to determine if global health diplomacy was able to, in whole or in parts, achieve peacebuilding objectives in northern Uganda.
Uganda 2025-01-30 18:24:54 2028-01-30 Social Science and Humanities Non-Clinical Trial Degree Award
Hilary Muheezangango
ID: UNCST-2024-R002492
GOVERNANCE PRACTICES AND ECONOMIC SECURITY IN PINEAPPLE VALUE CHAIN COMMUNITIES IN SELECTED DISTRICTS; CENTRAL UGANDA.
REFNo: SS3466ES

Main Objective: To examine the relationship between governance practices, and economic security of Pineapple Value Chain Communities in Central Uganda.

Specific objectives
i. To examine the contribution of shared goals among stakeholders on the economic security of Pineapple Value Chain Communities in the Districts of Luweero, Kayunga and Mukono; Central Uganda.
ii. To examine the relationship between shared roles and economic security of Pineapple Value Chain Communities of Luweero, Kayunga and Mukono Districts; Central Uganda.
iii. To analyze the relationship between shared knowledge and economic security of Pineapple Value Chain Communities of Luweero, Kayunga and Mukono Districts; Central Uganda.
iv. To assess the mediating effect of work environment on the relationship between governance practices and economic security in Pineapple Value Chain Communities of Luweero, Kayunga and Mukono Districts; Central Uganda.

Uganda 2025-01-24 14:40:20 2028-01-24 Social Science and Humanities Non-Clinical Trial Degree Award
Norah Babirye
ID: UNCST-2024-R015349
Optimising Indigenous Food Consumption for Improved Metabolic Health among Adults in Uganda.
REFNo: A549ES

1. To evaluate indigenous vegetable and fruit consumption patterns among adults in Wakiso district, Uganda.
2. To identify the sources of indigenous vegetable and fruit consumed among adults in Wakiso district, Uganda.
3. To document the cardiometabolic health profile of adults in Wakiso district, Uganda.

Uganda 2025-01-24 14:38:11 2028-01-24 Agricultural Sciences Non-Clinical Trial Degree Award
Laura Twubahe
ID: UNCST-2024-R002589
Nutritional, Physical-chemical, and Microbiological changes in the properties of cooking oil and street-vended deep-fried foods in Wakiso District, Central Uganda: A case study of Kira Municipality.
REFNo: HS5308ES

General objective
The general objective of this study is to evaluate the physical-chemical changes in cooking oil and the Microbiological safety of street vended deep fried foods in Kira Municipality, Wakiso District, Uganda.

Specific Objectives
The specific objectives of the study are to;
1. Assess the changes in the physical-chemical properties including trans fatty acids of cooking oil used by street vendors of Rolex and deep-fried chicken in Kira Municipality.
2. Assess the microbiological safety of street vended rolex and deep-fried chicken in Kira municipality.
3. Assess the knowledge, attitudes, and practices of street vendors of rolex and deep-fried chicken in Kira Municipality.

Uganda 2025-01-22 9:56:29 2028-01-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Robertson Turyamwijuka
ID: UNCST-2024-R015990
A sustainable Public procurement implementation framework for Public Sector Entities in Uganda.
REFNo: SS3597ES

3.1 PRIMARY OBJECTIVE The primary objective of this study seeks to develop and propose a sustainable public procurement implementation framework that will guide Ugandan public entities on how to enhance sustainable public procurement performance through the effective implementation of sustainable public procurement practices and approaches. This will enable these public entities to also address the unique challenges and opportunities they face, with the aim to enhance efficiency, accountability, and sustainability in public procurement processes. The accomplishment of the ensuing secondary objectives will enable this. 3.2 SECONDARY OBJECTIVES OF THE STUDY The following secondary objectives have been determined in order to fulfil the study's main goal: 3.2.1 To identify the drivers influencing the implementation of sustainable public procurement in public sector entities in Uganda. 3.2.2 To identify the sustainable public procurement practices currently implemented among Ugandan public sector entities. 3.2.3 To identify the challenges and their consequences faced by Ugandan public sector entities when implementing sustainable public procurement. 3.2.4 To identify sustainable public procurement approaches within public sector entities in Uganda. 3.2.5 To determine the influence of sustainable public procurement drivers on sustainable public procurement performance. 3.2.6 To determine the influence of the drivers of sustainable public procurement on sustainable public procurement approaches. 3.2.7 To assess the influence of sustainable public procurement drivers on the adoption of sustainable public procurement practices. 3.2.8 To assess the influence of sustainable public procurement approaches on sustainable public procurement practices. 3.2.9 To assess the influence of sustainable public procurement practices on sustainable public procurement performance. 3.2.10 To assess the influence of sustainable public procurement approaches on sustainable public procurement performance. 3.2.11 To assess how sustainable public procurement approaches, in Ugandan public sector organizations, mediate the relationship between sustainable public procurement drivers and sustainable public procurement performance. 3.2.12 To assess the mediating influence of sustainable public procurement practices on the association between sustainable public procurement drivers and sustainable public procurement performance in Ugandan government agencies. 3.2.13 To assess the mediating influence of sustainable public procurement practices on the association between sustainable public procurement approaches and sustainable public procurement performance within public sector entities in Uganda. 3.2.14 To provide a conceptual framework for Ugandan public sector entities to embrace sustainable public procurement.
Uganda 2025-01-22 17:09:13 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
Betty Adoch
ID: UNCST-2024-R003825
Land Conflicts and Livelihood Nexus in Gulu City, Northern Uganda
REFNo: SS3531ES

To assess the attitude and perceptions of inhabitants on effectiveness of land conflict resolution mechanisms in Gulu city,To assess the effects of land conflicts on livelihood capitals of inhabitants in Gulu city,To examine the drivers of land conflict among inhabitants in Gulu city,To determine the nature of land conflicts among inhabitants in Gulu city,The study aims to examine the nature and extent of land conflicts, explore how these conflicts affect the livelihood assets of the local population, and assess the effectiveness of existing mechanisms for conflict resolution. This study seeks to provide insights that can inform policy, and interventions aimed at improving land management and enhancing the livelihoods of the affected communities.,
Uganda 2025-01-22 17:07:20 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
Evaluating the performance, feasibility, acceptability and impact of treatment-decision algorithms for pulmonary tuberculosis in children in Uganda and their unmet social needs;TDA4Child
REFNo: HS5390ES

(i) To compare the diagnostic accuracy of the study TDAs with the Uganda national algorithm for the diagnosis of TB in children
(ii) To compare adults and children TB notifications before and after study initiation;
(iii) To describe the caregiver’s (parents or guardians) acceptability in introducing TB treatment based on the TDA outcome
(iv) To describe healthcare workers’ (HCWs) experience, acceptability of and satisfaction with and feasibility of algorithm the TDAs’ implementation
(v) To describe the unmet social needs, social protection coverage, and dissaving among children under 10 years old being evaluated for pulmonary TB and their households in Uganda.
Uganda 2025-01-22 17:04:40 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
Validation of the Quality of Dying and Death-Revised Global Version scale in Uganda
REFNo: SS3429ES

3) To assess the relationship between quality of death and dying and grief and bereavement symptoms reported by caregivers,2) To determine the reliability of the QODD-RGV,1) To examine face and content validity of the QODD-RGV index.,The main objective of this study is to undertake a psychometric evaluation of the Quality of Death and Dying Index. ,
Uganda 2025-01-22 16:56:37 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Clinical Performance Evaluation of Kwiq-Test HIV-1/2 (Whole Blood/Serum/ Plasma): Diagnostic sensitivity & diagnostic specificity, specimen equivalence, Anticoagulant equivalence and qualification of usability
REFNo: HS5368ES

The objectives of this study are:
1. To establish the diagnostic sensitivity and diagnostic specificity of the Kwiq HIV-1/2 test (Serum/Plasma/wholeblood) in plasma samples according to the WHO TSS-1 Part 2.1
2. To demonstrate the equivalence of serum, plasma (EDTA-K2), venous whole blood (EDTA-K2) and fingerprick whole blood collected from HIV positive patients according to WHO TSS-1 Part 1: 1.1.1.
3. To demonstrate anticoagulant equivalence of serum, venous whole blood (EDTA-K2, EDTA-K3, sodium citrate, sodium heparin), plasma (EDTA-K2, EDTA-K3, sodium citrate, sodium heparin) and fingerprick whole blood
4. To demonstrate the usability of this rapid diagnostic test when performed by the intended users. It will be assessed whether the intended users comprehend all key messages from labelling and packaging (i.e. label comprehension study) and whether they can correctly interpret pre-determined test results (i.e. result interpretation study).
To meet all the requirements as set out in the WHO TSS-1study will be conducted in Uganda

Uganda 2025-01-22 16:53:12 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Olds
ID: UNCST-2023-R006240
Developing Better Control Together, a multi-faceted patient-support group for patients with hypertension in Uganda
REFNo: HS5309ES

We propose to develop a multi-faceted patient-support group for patients living with HTN in rural Uganda using an iterative approach that is tailored to the local context. We will adapt several evidence-based interventions for patient-support groups from the HIV experience to develop a comprehensive intervention for patients with HTN by including aspects of disease education, social support, financial activities, and bulk purchasing of HTN medications.
USA 2025-01-22 16:51:40 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Rwankangi
ID: UNCST-2024-R016056
Solar-Powered Irrigation Schemes for Smallholder Farmers in Uganda: Assessing Impact and Sustainability
REFNo: SIR452ES

1. To examine the impact of adopting solar-powered irrigation systems on crop
yields in horticulture among smallholder farmers in eastern Uganda.

2. To examine how farmers’ knowledge and skills in operating and maintaining
solar irrigation systems influence the adoption of solar-powered irrigation
technology among smallholder farmers.

3. To analyze the effect of stakeholder engagement on the adoption of solar-
powered irrigation technologies among smallholder farmers.

4.To assess how the Ugandan Government’s policy frameworks influence, the
adoption of solar-powered irrigation technology among smallholder farmers.

Uganda 2025-01-22 16:49:32 2028-01-22 Engineering and Technology Non-Clinical Trial Degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
Functional Role, Temporal Dynamics, and Protective Impact of IgA on Clinical Outcomes in Uncomplicated Plasmodium falciparum Malaria
REFNo: HS5353ES

General Objective
To investigate the functional role, temporal dynamics, and protective impact of IgA on clinical outcomes in adult patients with uncomplicated Plasmodium falciparum malaria in the greater Kampala region, Uganda.
Specific Objectives
1. To quantify the functional activity of serum IgA antibodies in adult patients with uncomplicated Plasmodium falciparum malaria in the greater Kampala region, Uganda, by measuring the percentage reduction in hepatocyte infection, the inhibition of merozoite invasion of erythrocytes, and the level of neutrophil activation through oxidative burst and cytokine release.
2. To characterize the temporal dynamics and persistence of IgA responses in adult patients with uncomplicated malaria in the greater Kampala region over a 42-day follow-up period, by measuring peak IgA levels (C_max), time to peak level (T_max), rate of decline (IgA half-life), and area under the curve (AUC).
3. To evaluate the association between serum IgA levels and clinical outcomes in adult patients with uncomplicated malaria in the greater Kampala region, by assessing symptom resolution time and parasite clearance time.
4. To determine the correlation between IgA levels and complement activation, as well as their association with pro-inflammatory or regulatory cytokines during and after Plasmodium falciparum infection in adult patients with uncomplicated malaria in the greater Kampala region, Uganda.

Uganda 2025-01-22 16:47:42 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dina Nabasumba
ID: UNCST-2023-R006504
Crop production dynamics and vulnerability to food insecurity in the face of climate variability: A case of smallholder farmers in south-western Uganda
REFNo: A524ES

4. To classify the extent and factors controlling the influence of climate variability on vulnerability to food insecurity among smallholder farmers in south-western Uganda,3. To determine the influence of spatial-temporal rainfall variability on adoption patterns of land-based climate smart agricultural practices in seasonal cropping systems of smallholder farmers in south-western Uganda ,2. To establish the relationship between smallholder farmers’ knowledge, attitudes and adoption of climate smart agricultural practices in south-western Uganda,1. To assess smallholder farmers’ perceptions of climate variability and the extent to which it has altered crop selection and cultivation patterns in south-western Uganda,To establish the influence of climate variability on the crop production systems and vulnerability to food insecurity among smallholder farmers in south-western Uganda,
Uganda 2025-01-22 16:46:28 2028-01-22 Agricultural Sciences Non-Clinical Trial Degree Award
Chikadibia Uche Kalu Awa
ID: UNCST-2024-R003818
OPTIMIZATION OF MIX DESIGN FOR STRUCTURAL LIGHTWEIGHT CONCRETE (SLWC) WITH ARTIFICIAL AGGREGATES USING RESPONSE SURFACE METHODOLOGY
REFNo: SIR344ES

1. To produce and characterize artificial aggregates from polyethylene terephthalate plastic waste.
2. To design experimental mixture proportions for S.L.W.C. using mathematically independent variable (factorial) approach.
3. To evaluate the performance of S.L.W.C. regarding density, splitting tensile strength, compressive strength, workability, and durability.
4. To apply response surface methodology for the analysis of the obtained results to derive model equations for each performance criteria.
5. To optimize (S.L.W.C.) using desirability function.
6. To carry out microstructural analysis of the specimens.

Nigeria 2025-01-22 16:45:23 2028-01-22 Engineering and Technology Non-Clinical Trial Degree Award
SIMON MUCHURO
ID: UNCST-2024-R003624
Estimation of TB notification rates among healthcare workers in 2023 and assessment of associated healthcare worker and health facility characteristics
REFNo: HS5200ES

Primary objective:
1. To establish the TB notification rates among healthcare workers
2. To establish the risk factors associated with TB disease
Secondary objectives:
3. To determine TB treatment outcomes among healthcare workers started on drug sensitive TB treatment from 1st January to 31st December 20
Uganda 2025-01-22 16:44:20 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Muwonge Ssajjabbi
ID: UNCST-2023-R007179
AN INVESTIGATION INTO THE IMPACT OF TELEMEDICINE ON PATIENT OUTCOMES IN KAMPALA DISTRICT. A CASE OF RUBAGA DIVISION
REFNo: HS4901ES

iii. To investigate the extent to which telemedicine improves patient satisfaction for patients in Lubaga division. ,ii. To assess the impact of telemedicine on accessibility of health care services for patients in Lubaga division. ,i. To identify the barriers and facilitators of telemedicine adoption and how they impact patient outcomes in Lubaga division. ,To investigate the impact of telemedicine on patient outcomes in Kampala district, with emphasis on Lubaga division so as to improve the quality of health-care service delivery.,
Uganda 2025-01-22 16:38:30 2028-01-22 Medical and Health Sciences Non-Clinical Trial Degree Award
ROSE AKULLO
ID: UNCST-2024-R005155
LEADERSHIP BEHAVIOR IN MANAGEMENT OF CURRICULUM CHANGES IN THE LOWER SECONDARY SCHOOLS IN KARAMOJA REGION, NORTH EASTERN UGANDA.
REFNo: SS3120ES

5. Determine the mediating effect of organizational climate on the relationship between leadership behaviours and curriculum change management in the lower secondary curriculum,4. To assess the impact of leadership behaviour on the level of teacher support for curriculum change management in lower secondary schools in the Karamoja Region, Uganda.,3. Establish the effect of change-oriented leadership behaviours on management of curriculum changes in secondary schools in Karamoja ,2. Assess the effect of task-oriented leadership behaviours on management of curriculum changes in lower secondary schools in the Karamoja Region, Uganda.,1.Examine the effect of relation-oriented leadership behaviours on management of curriculum changes in secondary schools in Karamoja,To investigate the effect of leadership behaviors on management of curriculum changes in secondary schools in Karamoja region, North Eastern Uganda.,
Uganda 2025-01-22 16:33:52 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
BONIFACE OJOK
ID: UNCST-2023-R006075
Lok Ber Bedo Study: Storytelling with young people affected by conflict in Acholi sub-region, northern Uganda
REFNo: SS3437ES

1. General objective: The proposed project seeks to engage groups of young people affected by conflict in Acholi sub-region to explore the extent to which storytelling can be harnessed to promote shared understanding of the wholesome character of ber bedo (Acholi meaning 'wellbeing) and collective action to advance ber bedo.

2. Specific objectives
(1) To explore conflict affected young people’s understanding of ber bedo and practice of storytelling in Acholi sub-region.
(2) To identify challenges to ber bedo among young people affected by conflict in Acholi sub-region and to explore existing and potential strategies to address these.
(3) To assess to what extent the 'lok ber bedo' (Acholi meaning 'let's talk well-being') storytelling approach can be transformational, in its various dimensions, for young people affected by conflict in Acholi sub-region.
Uganda 2025-01-22 16:24:55 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nabusige Gesa Jean Brenda
ID: UNCST-2024-R005397
Acaricide exposure and associated genotoxicity in farmers of the cattle corridor: a case study of Kiruhura district
REFNo: HS5250ES

To determine oxidative stress, inflammatory and genotoxicity outcomes among pesticide exposed farmers and establish their relationship with pesticide exposure.,To quantify residues of selected pesticides in raw cows milk and open well water, as well as human and animal serum and determine factors associated with these residue levels. ,To assess Knowledge, Attitudes, and Practices towards pesticide use and factors associated with variations therewith among farmers.,To investigate farmers Knowledge, Attitudes and Practices towards pesticide use, farm ecosystem exposure, associated outcomes to human health and genotoxicity among pesticide exposed farmers.,
Uganda 2025-01-22 15:51:36 2028-01-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Elly Atuhumuza
ID: UNCST-2024-R002706
Assessing Effectiveness of Interpersonal Group Therapy for Depression on Academic Performance in Ugandan Schools
REFNo: SS3249ES

To describe the feasibility and acceptability of implementing IPT-G within the school setting,To determine the effects of IPT-G on the academic performance of students by measuring improvements in grades, attendance, and overall academic engagement.,To determine the effects of Interpersonal Group Therapy (IPT-G) on reducing depressive symptoms among school-aged adolescents in Uganda. ,The general objective is to evaluate the effectiveness of Interpersonal Group Therapy (IPT-G) in improving the mental health and academic performance of students in Ugandan schools.,
Uganda 2025-01-22 15:47:24 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richardson Mafigiri
ID: UNCST-2024-R003907
HEALTH WORKERS PRACTICES AND PERFORMANCE OF HEALTHCARE PROJECTS IN KAYUNGA DISTRICT, UGANDA
REFNo: SS3194ES

iv. To examine the relationship between policy support and performance of health projects in Kayunga district,iii. To establish practical strategies to improve Performance of health projects in Kayunga District ,ii. To examine the effect of vaccine management by health workers on Performance of health projects in Kayunga District.,i. To determine the effect of surveillance practices by health workers on Performance of health projects in Kayunga District.,The purpose of the study will be to assess the effect of health workers’ practices on performance of health projects in Uganda,
Uganda 2025-01-22 15:42:36 2028-01-22 Social Science and Humanities Non-Clinical Trial Degree Award
Juma Said Tusubila
ID: UNCST-2024-R005319
Using Photovoice to examine the burden and experiences of refugee caretakers of children with special health care needs in Rhino Camp refugee settlement in West Nile, Uganda
REFNo: HS5441ES

● To explore the physical, emotional, and financial challenges (burden) faced by refugee caretakers of CSHCN in Rhino Camp Refugee Settlement, West Nile ● To understand the coping mechanisms and resilience of refugee caretakers in of CSHCN in a refugee settlement in Rhino Camp refugee settlement, West Nile. ● To generate insights on the support systems, barriers, and facilitators to improve the well-being of caretakers of CSHCN in a refugee settlement in Rhino Camp refugee settlement, West Nile.
Uganda 2025-01-22 15:08:17 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
‘5 Rs to Rescue’ A quality improvement initiative with a cluster trial evaluation and embedded process evaluation
REFNo: HS5020ES

To evaluate the effect of the QI intervention on: 1. 30 day in-hospital mortality. 2. Duration of hospital stay.,To evaluate whether implementation of the ‘5 Rs to Rescue’ quality improvement intervention increases surveillance for patients at risk of ‘failure to rescue’ after surgery in hospitals in Africa.,
UK 2025-01-22 12:30:25 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Immaculate  Nankya Lillian
ID: UNCST-2020-R014784
Interplay between Estrogen, immune activation and HIV persistence during pregnancy
REFNo: SS3319ES

To characterize the clonal dynamics and diversity within the circulating latent reservoir in pregnant women on ART who are experiencing low-level viremia, viral blips, and persistently non-suppressed virus. ,To measure fluctuations in inflammation and immune activation markers, estrogen, and reservoir dynamics in women during pregnancy. , The main goal of this protocol is to understand the interplay between estrogen, markers of immune activation and the reservoir dynamics among pregnant women.,
Uganda 2025-01-22 11:58:29 2028-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
JUDITH NASSAAZI
ID: UNCST-2023-R007664
Comparing in-person versus virtual postoperative review appointments for children following guided growth surgery at CORSU Hospital, Uganda
REFNo: HS5268ES

Study Objectives
Primary objectives
To compare the show-rates of in-person versus virtual/telehealth post-operative review appointments for children following guided growth surgery at CoRSU Hospital

Secondary objectives.
1.To compare parental satisfaction of in-person versus virtual appointments
2.To determine the factors that facilitate in-person and virtual appointments following guided growth surgery.
3.To compare the rate of post-operative complications following in-person follow-up versus virtual follow-up
Uganda 2025-01-22 10:12:27 2028-01-22 Medical and Health Sciences Clinical Trial Non-degree Award
SABRINA KITAKA BAKEERA
ID: UNCST-2020-R014290
GENERATING LOCAL DATA ON HPV VACCINATION IMPACT AND TRAINING NEEDS AT THE LEVEL OF VACCINE IMPLEMENTERS – A FEASIBILITY STUDY
REFNo: HS5219ES

1) generate local data on HPV vaccine induced immune response and HPV infection prevalence using first-void urine (FVU) in Uganda and assess feasibility of conducting such studies, 2) assess knowledge and training gaps among HCWs in Uganda and standardize HPV vaccine training barometer survey,
Uganda 2025-01-22 10:09:20 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MUSANA SAMSON ISRAEL
ID: UNCST-2024-R016481
RELIGIOUS MISSION FIELD RIVALRIES AND ITS IMPACT ON CHRISTIAN-MUSLIM PEACEFUL COEXISTENCE IN MBALE CITY, UGANDA
REFNo: SS3541ES

1) to investigate the root causes of religious mission field rivalries affecting Christian-Muslim peaceful coexistence. 2) to establish Christian and Muslim missionary methods being utilised in the
mission field; and 3) to ascertain the impact of Christian and Muslim missionary outreach
practices.
Uganda 2025-01-10 12:29:51 2028-01-10 Social Science and Humanities Non-Clinical Trial Degree Award
Venantius Bbaale Kirwana Bbaale
ID: UNCST-2024-R002370
Behind the Scenes: Young women and gender-based inequities in Africa’s Creative Sector -Uganda research project
REFNo: SS3483ES

iii. Provide evidence-based recommendations and best practices for key stakeholders that can support gender equity in Uganda\'s creative industries and workplaces.,ii. Map the Creative Sector in Uganda to understand its organization in terms of stakeholders, policies, potential, remuneration systems, accessibility to different categories of youth, challenges, conduct codes, job creation opportunities, funding, education, training, products, and services.,i. To generate and disseminate evidence on the nature, dynamics, and implications of gender-based inequities faced by young female creatives in Uganda and other countries in the project.,
Uganda 2025-01-10 12:12:15 2028-01-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Justine Namuli Diana
ID: UNCST-2021-R011844
ENHANCING COMPREHENSION OF INFORMED CONSENT IN RESEARCH INVOLVING PATIENTS WITH PSYCHOTIC DISORDERS USING AUDIO-VISUAL AIDS
REFNo: HS5358ES

To evaluate the comprehension of informed consent, identify key factors that are associated with comprehension of consent, determine the feasibility, acceptability, and preliminary effectiveness of audio-visual aids on enhancing the comprehension of consent information during the consenting process in research involving individuals with psychotic disorders
Uganda 2025-01-10 12:00:57 2028-01-10 Medical and Health Sciences Clinical Trial Degree Award
Baguma Deus Bagambana
ID: UNCST-2024-R002898
AGRONOMIC AND UTILIZATION POTENTIAL OF COCOYAM IN SOUTH WESTERN HIGHLANDS AGRO-ECOLOGICAL ZONE OF UGANDA
REFNo: NS888ES

1. To establish cocoyam production practices, constraints and trait preferences in the south western highlands agroecological zone of Uganda.
2. To establish the facilitators and barriers of cocoyam utilization by value chain end users in south western highlands agroecological zone of Uganda
3. To determine edaphoclimatic suitability of cocoyam production in the south western highlands agroecological zone of Uganda
4. To establish the feasibility of utilisation of cocoyam flour for production of cookies in south western highlands agroecological zone of Uganda

Uganda 2025-01-10 11:58:50 2028-01-10 Natural Sciences Non-Clinical Trial Degree Award
BAINA NAKANWAGI
ID: UNCST-2024-R002838
Financial Literacy and performance of Micro and small businesses owned by muslim women in Mbarara city,Uganda
REFNo: SS3493ES

i) To assess the effect of Islamic finance principles on performance of micro and small businesses owned by muslim women in Mbarara City
ii) To evaluate the impact of debt management on performance micro and small businesses owned by muslim women in Mbarara city
iii)To evaluate the impact of finance planning and budgeting on performance micro and small businesses owned by muslim women in Mbarara city
iv) To establish the moderating effect of access to finance on the relationship between financial literacy and performance of micro and small enterprise owned by muslim women in Mbarara city
1.5 Research Questions
i) What is the effect of Islamic finance principles on the performance of micro and small businesses owned by Muslim women in Mbarara City?
ii) What is the impact of debt management on the performance of micro and small businesses owned by Muslim women in Mbarara City?
iii) How does financial planning and budgeting affect the performance of micro and small businesses owned by Muslim women in Mbarara City?
iv) What is the moderating effect of access to finance on the relationship between financial literacy and the performance of micro and small enterprises owned by Muslim women in Mbarara City?

Uganda 2025-01-10 11:57:43 2028-01-10 Social Science and Humanities Non-Clinical Trial Degree Award
Ali Ndiwalana
ID: UNCST-2024-R015333
Evaluation of UNICEF’s contribution towards addressing equitable access to quality, inclusive education for vulnerable children and adolescents in Uganda 2021-2024
REFNo: SS3478ES

The evaluation that will assess the relevance and effectiveness of UNICEF's contributions towards achieving the goals set for the BEAD
programme under the CPD 2021-2025. The evaluation's findings are expected to guide the design of UNICEF's future learning and skilling programs in Uganda
Uganda 2025-01-10 11:56:23 2028-01-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jackline  Akello
ID: UNCST-2023-R005827
Sickle cell disease in pregnancy: Experiences in provision and access to care and adverse pregnancy outcomes at Mbale and Kawempe Referral Hospitals
REFNo: HS5315ES

4.To explore health providers experiences in providing care to pregnant women with SCD at Mbale and Kawempe referral hospitals. ,To explore experiences of pregnant women with SCD in accessing health care at Kawempe and Mbale referral Hospitals. ,2.To determine risk factors for adverse fetal outcomes among pregnant women with SCD at Mbale and Kawempe Referral Hospitals,To determine risk factors for adverse maternal outcomes among pregnant women with SCD at Mbale and Kawempe Referral Hospitals ,The general objective is to determine the adverse maternal and fetal outcomes associated with pregnancies complicated by SCD and explore experiences in access and provision of care at Mbale and Kawempe Referral Hospitals. ,
Uganda 2025-01-10 11:54:49 2028-01-10 Medical and Health Sciences Non-Clinical Trial Degree Award
BABTUNDE SAMUEL ADEBAYO
ID: UNCST-2024-R002460
The Endline Evaluation of CorpsAfrica's Community Development Interventions in Uganda (FY23/24)
REFNo: SS3428ES

The objective of the Endline Evaluation of CorpsAfrica's Community Development Interventions in Uganda (FY23/24) is to assess the impact, effectiveness, and sustainability of interventions implemented by CorpsAfrica volunteers across four districts—Buikwe, Lyantonde, Mpigi, and Kabarole. The evaluation aims to measure changes in community development outcomes, assess improvements in livelihoods, and document the role of volunteers in addressing the needs of these communities. Furthermore, the evaluation will capture lessons learned, identify best practices, explore community acceptance, and assess stakeholder contributions, ultimately providing valuable insights for improving and scaling similar community-led development initiatives in Uganda and beyond.
Nigeria 2025-01-10 11:53:04 2028-01-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
JUDITH NASSAAZI
ID: UNCST-2023-R007664
HIP SURVEILLANCE IN PAEDIATRIC PATIENTS WITH CEREBRAL PALSY AT CoRSU REHABILITATION HOSPITAL
REFNo: HS5220ES

Primary objective
1. To assess the feasibility of implementing a hip surveillance program in detecting early signs of displacement among cerebral palsy patients attending CoRSU hospital in 2024-2025
2. To determine the incidence of hip dislocation in patients with cerebral palsy seen at CoRSU hospital in 2024-2025
Secondary objectives
1. To assess changes in the QOL of life of children after joining the hip surveillance program on hip displacement among children with cerebral palsy seen at CoRSU hospital in 2024-2025

2. To develop a standard for frequency of pelvic x-rays for children with cerebral palsy seen at CoRSU hospital in 2024-2025

3. To evaluate the benefits and complications of early intervention measures on reducing hip displacement cerebral palsy seen at CoRSU hospital in 2024-2025

Uganda 2025-01-10 11:51:15 2028-01-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
Sub-Study D – Evaluation of Point-of-Care C-reactive Protein Assay Performed on the EnLiSense Rapid ElectroAnalytical Device (READ) Platform Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS5172ES

To validate the CRP assay performed on the READ platform by comparing it to a point-of-care conventional CRP assay previously cleared by the United States Food and Drug Administration (FDA). The results from this substudy are intended to be used for a FDA 510(k) submission for the EnLiSense READ device and CRP assay
Uganda 2025-01-10 11:49:48 2028-01-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ferdinand Nduwayo
ID: UNCST-2024-R004506
Development of Comprehensive Seismic Design Guidelines for Earthquake Resistant Design of Buildings in Uganda
REFNo: SIR390ES

(e) To develop comprehensive national structural design guidelines based on modern seismic design codes, aimed at providing engineering practitioners with practical seismic risk mitigation techniques; subsequently leading to sustainable growth and development,(d) To derive spectral displacement, elastic and design pseudo-acceleration spectra representing seismic action in the horizontal direction for key building typologies located in major cities in Uganda,(c) To develop reliable bespoke building exposure models for risk calculations by gathering data on building stock taxonomies and occupancy types,(b) To perform a stochastic event-based probabilistic seismic hazard analysis for Uganda which relies on the available data collected on the seismicity, geology and tectonics of the country,(a) To compile Uganda historical and instrumental earthquake catalogues required for homogenisation, removal of non-Poissonian events and completeness analyses,The main objective of this research proposal is to develop comprehensive earthquake-resistant building design guidelines specifically tailored for Uganda\'s unique geological, seismo-tectonic conditions and available construction materials. These guidelines will facilitate the construction of buildings that can withstand earthquakes, thereby reducing the potential for damage and casualties during seismic events.,
Burundi 2025-01-10 11:48:15 2028-01-10 Engineering and Technology Non-Clinical Trial Non-degree Award
Julius Okuni Boniface
ID: UNCST-2019-R000963
A One Health Survey of AMR and farming practices that drive Antimicrobial Resistance at Selected Animal-Human-environment Interface in Uganda
REFNo: A539ES

General Objective: To build capacity for antimicrobial resistance (AMR) surveillance and AMR stewardship using a One Health approach.

Specific Objectives:
1. To isolate the AMR resistant E coli and Salmonella from slaughtered chicken, slaughtered cattle and the environment. 2. To determine the phenotypic and genotypic characteristics of Salmonella and pathogenic E. coli present in selected human-animal interfaces in Uganda. 3. To determine the changes in the antimicrobial use by farmers and Veterinarians during COVID19 pandemic.
4. To determine the roles played by different livestock management practices and animal health interventions in escalating AMR in Uganda. 5. To identify and evaluate community based hygienic and disinfection practices that can reduce antibiotic/biocide use. 6. To determine the levels of antimicrobials and biocide residues in slaughtered chicken and cattle cecal samples and abattoir/market wastewater from the selected districts in the country. Secondary objectives: To harness the functions of various policy makers in government institution and build capacity and partnerships for AMR reduction with different organisations within Uganda.
Uganda 2025-01-10 11:46:51 2028-01-10 Agricultural Sciences Non-Clinical Trial Non-degree Award
Ilemobayo  Fasogbon Victor
ID: UNCST-2023-R008569
DEVELOPMENT AND EVALUATION OF AN APTAMER-BASED LATERAL FLOW BIOSENSOR FOR RAPID DETECTION OF Mycoplasma bovis P48 PROTEIN
REFNo: HS4931ES

Evaluation of the aptamer-based biosensor using M. bovis infected milk samples,Construction of the aptamer-based biosensor after optimizing the inherent conditions and components,Characterization of the binding affinity and specificity of the aptamer-target interactions,Selection and optimization of the most sensitive aptamer for application in the lateral flow biosensor through molecular interaction studies on previously reported P48 protein aptamers.,he research aim to develop and evaluate an aptamer-based lateral flow biosensor for the rapid and accurate detection of the Mycoplasma bovis P48 protein in infected samples,
Nigeria 2024-12-23 12:36:24 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Paul Matovu
ID: UNCST-2024-R004929
The Phylogeny of East African Chlorophytum Ker-Gawl. (Asparagaceae), Phylogeography and Conservation of species found in Uganda
REFNo: NS756ES

1. To establish the phylogeny of Chlorophytum species in the FTEA region and put them in a global context.
2. To unravel the phylogenetic and morphological delimitation of problematic taxa and species complexes within Chlorophytum.
3. To establish the spatial phylogeny of Chlorophytum species that occur in Uganda
4. To establish the conservation status of Chlorophytum species in Uganda

Uganda 2024-12-23 12:34:57 2027-12-23 Natural Sciences Non-Clinical Trial Degree Award
Francis Ssali
ID: UNCST-2021-R012134
A5409: A Phase 2 Randomized, Adaptive, Dose-Ranging, Open-Label Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)
REFNo: HS4036ES

1.2 Primary Objectives

1.2.1 To compare MGIT liquid culture TTP slope over the first 6 weeks of treatment for each experimental treatment arm to the SOC arm.

1.2.2 To compare new Grade 3 or higher adverse events (AEs) (safety) over the first 8 weeks of treatment for each experimental treatment arm to the SOC arm.

1.3 Secondary Objectives

1.3.1 To compare time to stable culture conversion by MGIT liquid culture by week 8 for each experimental treatment arm to the SOC arm.

1.3.2 To compare MGIT liquid culture TTP slope over the first 8 weeks of treatment for each experimental treatment arm to the SOC arm.

1.3.3 To compare new Grade 3 or higher AEs (safety) over 26 weeks of treatment for each experimental treatment arm to the SOC arm.

1.3.4 To compare discontinuations of anti-TB drugs for any reason prior to 8 and 26 weeks of treatment for each experimental treatment arm to the SOC arm.

1.3.5 To determine the dose- and exposure-response relationships between experimental drug estimated pharmacokinetic (PK) parameters with safety and efficacy.

1.3.6 To compare a composite of efficacy and safety outcomes using a risk-benefit approach for each experimental treatment arm to the SOC arm.

1.3.7 To compare MGIT liquid culture TTP slope over the first 6 weeks of treatment for Arms 3A-3B and Arms 4A-4B compared to Arm 2.

1.3.8 To compare durable cure by 52 weeks after treatment initiation in each experimental treatment arm to the SOC arm.


Uganda 2024-12-23 12:34:14 2027-12-23 Medical and Health Sciences Clinical Trial Non-degree Award
Hakimu Sseviiri
ID: UNCST-2024-R004881
Formalizing and Elevating Workforce Visibility for Marginalized Sanitation Workers in Kampala, Uganda: Unravelling the intended and Unintended Consequences.
REFNo: SS2816ES

4. To co-design multi-stakeholder pathways towards effective formalization, integration and recognition of sanitation workers. ,3. To analyze the multi-dimensional intended and unintended impacts of formalizing and increasing the visibility of the workforce for the most marginalized workers. ,2. To identify and characterize actors involved in the formalization and visibility raising processes in Kampala city. ,1.To determine the different sanitation workers’ formalization and visibility raising initiatives overtime. ,To unravel the intended and unintended consequences of sanitation workers formalization and visibility enrichment in Kampala city, Uganda. ,
Uganda 2024-12-23 12:29:36 2027-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
George Alaneme Uwadiegwu
ID: UNCST-2024-R003261
ARTIFICIAL INTELLIGENCE PREDICTIVE MODELLING OF MECHANICAL AND RHEOLOGICAL PROPERTIES OF GEOPOLYMER-CONCRETE MADE FROM BLENDED BAGASSE AND BANANA-PEEL-ASH
REFNo: SIR365ES

i. To characterize Bagasse ash (BA) and Banana peel ash (BPA) as a geopolymer precursor
ii. To ascertain the optimal combination of the concrete mixture incorporating Bagasse ash (BA) and Banana peel ash (BPA) to replace ordinary Portland cement.
iii. To determine the mechanical and rheological properties of Bagasse ash (BA) and Banana peel ash (BPA) and blended geopolymer concrete matrix.
iv. To develop soft computing predictive models of ANN, GEP and ANFIS to explore the relationships between the Alkalis-activated binder blend and the rheological and mechanical strength response.
v. To compare and validate the models developed in (iv).

Nigeria 2024-12-23 12:28:18 2027-12-23 Engineering and Technology Non-Clinical Trial Degree Award
Sarah Wambete Namee
ID: UNCST-2024-R003551
Effectiveness Of A Health Belief Model (HBM)-Based Educational Intervention On Tuberculosis (TB) Treatment Adherence Among Tb Patients In Two Hospitals In Kampala, Uganda: A Randomized Control Trial
REFNo: HS4558ES

To assess the effectiveness of a Health Belief Model (HBM)-based educational intervention on TB treatment Adherence level among TB patients in two hospitals in Kampala, Uganda. 1.To assess the level of TB knowledge among TB patients in two hospitals in Kampala, Uganda. 2.To assess the health beliefs of TB patients towards tuberculosis in two hospitals in Kampala, Uganda 3.To assess the quality of life of TB patients in two hospitals in Kampala, Uganda.
Uganda 2024-12-23 12:26:18 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Piloya Ruth
ID: UNCST-2024-R003592
Patriarchy and Women Engagement in Environmental Conservation in Northern Uganda: A Case of Gulu District
REFNo: SS2986ES

4. To propose a framework or a model for effective engagement of women in environmental conservation in patriarchal societies.,3. To establish the effectiveness of the strategies used by stakeholders in fostering women’s engagement in environmental conservation within a patriarchal setting in Gulu district.,2. To investigate the extent to which the distinguishing features of patriarchy affect women’s engagement in environmental conservation in Gulu district.,1. To examine in context, the socio-cultural roles performed by women in environmental conservation within the patriarchal structure in Gulu district. ,To examine the extent to which patriarchy affects women\'s engagement in environmental conservation in Gulu district.,
Uganda 2024-12-23 12:24:42 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
Henry Mugerwa
ID: UNCST-2019-R000420
A Phase 1b, Age De-Escalation/Dose Escalation Trial to Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in an African Population of Adults and Children in a Setting of Perennial Malaria Transmission
REFNo: HS5298ES

Primary Objective. To assess the safety and tolerability of MAM01. Secondary Objectives. To assess the safety of MAM01. To characterize the PK of MAM01 following SC, IV, and IM administration of MAM01. To assess the formation of anti-drug antibodies (ADAs) to MAM01. Exploratory Objectives. To assess the protective efficacy of a single dose of MAM01 over 182 days against Pf infection, as detected by blood smear microscopy compared to a placebo. To assess the protective efficacy of a single dose of MAM01 over 182 days against Pf infection, as detected by blood smear microscopy compared to placebo. To assess the protection of MAM01 against events of malaria illness (first/only and all episodes). To correlate MAM01 concentration with Pf infection risk. To assess the complexity of Pf infection following administration of MAM01 or placebo.
Uganda 2024-12-23 12:23:27 2027-12-23 Medical and Health Sciences Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
Outcome Evaluation of the Young People and Adolescent Peer Support (YAPS) program Implementation in Uganda
REFNo: HS4809ES

1. To assess fidelity of the YAPS program implementation by different stakeholders (MoH, Implementing Partners, Districts, Facilities, and YAPS personnel)
2. To establish the effect of the YAPS program on the clinical cascade for Adolescents and Young People Living with HIV.
3. To explore perspectives of YAPS and other stakeholders on the effectiveness of the YAPS program.
4. To estimate the incremental costs of implementing the YAPS model at the different levels of implementation (National, District and health facility)

Uganda 2024-12-23 12:17:40 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DANLADI MAKERI
ID: UNCST-2024-R005300
Characterization of Staphylococcus aureus Isolated from Foot Ulcers of Diabetic Patients Attending Kampala International University Teaching Hospital, Bushenyi District, Uganda
REFNo: HS4836ES

v. To determine the molecular phylogeny of Staphylococcus aureus isolated from foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda,iv. To determine the antibiogram profile of Staphylococcus aureus isolated from foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda,iii. To assess the phenotypic distribution of Staphylococcus aureus in foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda.,ii. To determine factors associated with diabetic foot infections among Diabetic patients with foot ulcers attending Kampala International University Teaching Hospital Bushenyi district, Uganda ,i. To determine the prevalence of diabetic foot infection among Diabetic patients with foot ulcers attending Kampala International University Teaching Hospital Bushenyi district, Uganda,To characterize Staphylococcus aureus isolated from foot ulcers of Diabetic patients attending Kampala International University Teaching Hospital Bushenyi district, Uganda ,
Nigeria 2024-12-23 12:15:59 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Omujal
ID: UNCST-2019-R000428
DOCUMENTATION OF BATWA INDIGENOUS PEOPLE AND LOCAL COMMUNITIES’ KNOWLEDGE FOR BIO-PROSPECTING FOR THERAPEUTICS PRODUCTS
REFNo: NS658ES

c) To identify priority natural medicinal resources that can be used by BIP for development of therapeutic products for specific diseases ,b) To assess the availability status of medicinal resources used for TMK by the BIP,a) To document the traditional medicine practices of the BIP,To document TMK of the Batwa indigenous people for the development of therapeutic products.,
Uganda 2024-12-23 12:14:59 2027-12-23 Natural Sciences Non-Clinical Trial Non-degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Epidemiology of pediatric severe malaria in the Kasese District of western Uganda
REFNo: HS5367ES

Study Objectives The overarching goal of this proposed project is to describe the epidemiology of severe malaria among children in the Kasese District of western Uganda. Our scientific objective is to determine if the demographic, clinical, and laboratory characteristics of children admitted to a more urban level IV health center are different from our previous findings at a rural level III health center. To test this hypothesis, we propose to: AIM 1: Describe the demographic characteristics of children admitted to SPHC with a diagnosis of malaria. We will conduct a prospective, observational study, enrolling children admitted to the IPD. Participating caregivers will complete a questionnaire documenting basic demographic factors as well as information about the household (e.g., location, LLIN access and use). We hypothesize that most children will be (i) <12 years of age, (ii) from areas within 20km of SPHC, and (iii) have previously sought care at lower-level facilities. AIM 2: Document the clinical and laboratory characteristics of children admitted to SPHC with a diagnosis of malaria: We will elicit a history of illness from the caregiver and record relevant information including vital signs, results of laboratory testing (e.g., malaria RDT, hemoglobin, etc.), along with treatments administered during the hospitalization. We hypothesize that nearly all children will receive ≥24 hours of intravenous artesunate, but there may be substantial variation in dosing. AIM 3: Estimate measures of severe malaria incidence and associated morbidity and mortality among children presenting to SPHC with malaria. We will record the results of laboratory testing for malaria in the OPD to determine the malaria positivity rate and incidence of SM (i.e., proportion with a positive RDT who are admitted). Among those who are admitted, we will document disposition (e.g., discharge, transfer, death) and complete follow up at 14, 30, 45, and 60 days post-discharge. We hypothesize that mortality will be greatest among children referred from lower-level facilities and those with delayed presentations
Uganda 2024-12-23 12:12:56 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Justus Asasira
ID: UNCST-2021-R012092
Socioeconomic and Environmental Impacts of Biomass Briquettes and Solar Cooking Technologies Acceptance by Households in Southwestern Uganda
REFNo: SS2319ES

1. To explore the stakeholders’ perceptions about adopting biomass briquettes for cooking in Southwestern Uganda.
2. To assess the influence of business models on the acceptance and economic feasibility of biomass briquettes and solar technologies for cooking in Southwestern Uganda.
3. To compare the environmental impacts and benefits of producing and using solar technologies with non-renewable sources of energy for cooking in Southwestern Uganda.
4. To identify the design attributes that make biomass briquettes and solar cooking technologies socially acceptable by households in Southwestern Uganda.

Uganda 2024-12-23 12:11:58 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
OSCAR AYUYA INGASIA
ID: UNCST-2024-R002553
Gender Analysis; Address gendered aspects of awareness of lower-risk plant protection products/technologies in Uganda
REFNo: A534ES

To explore the roles men and women play in pest management and the products used for pest management in potato farming,To assess the differences between men, women, and young people\'s, values, power dynamics and behaviors which shape their access to and use of digital tools.,To examine the traditional pest prevention technologies, and the gendered obstacles faced by men women and young people,To respond to the needs of farmers and the systems that support them, by helping countries predict, prevent, and prepare for plant health threats, thereby reducing crop losses. ,
Kenya 2024-12-23 12:09:26 2027-12-23 Agricultural Sciences Non-Clinical Trial Non-degree Award
Isaac Kitone
ID: UNCST-2024-R002847
Kabale University (KAB) Sustainable Energy Generation System (KSEG) Project
REFNo: SIR421ES

To test the automated non-fossil fuel driven power generator,To construct an automated non-fossil fuel driven power generator ,To design an automated non-fossil fuel driven power generator ,To collect data on existing generator power needs in three western Ugandan districts, Kabale, Mbarara and Ntungamo,To design and construct an automated non-fossil fuel driven power generator ,
Uganda 2024-12-23 12:07:01 2027-12-23 Engineering and Technology Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
UNMET ORAL HEALTH NEEDS AND BARRIERS TO ORAL HEALTH AND SEXUAL HEALTH SERVICE UTILISATION AMONG MEN WHO HAVE SEX WITH MEN AND TRANSGENDER PEOPLE IN UGANDA: A MIXED METHODS PILOT STUDY
REFNo: HS5226ES

Objective 1: Estimate the prevalence of oral diseases, HIV, OHPV,
and self-reported STIs and their impact on oral health conditions in
MSM/TGP.
Objective 2: Identify the key barriers to health service utilization
experienced by MSM/TGP.
Uganda 2024-12-23 12:05:34 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOYCE NAMWASE
ID: UNCST-2024-R005002
FEASIBILITY AND EFFECTIVENESS OF A TRAINING INTERVENTION FOR INFORMAL CAREGIVERS OF PEOPLE LIVING WITH DEMENTIA IN RURAL UGANDA (FETIC-DU)
REFNo: HS5165ES

3. To evaluate the feasibility and effectiveness of the training program in improving knowledge and skills of informal care givers for persons with dementia in rural Uganda. 1.4 Research questions
Uganda 2024-12-23 12:04:08 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Murokora Murokora
ID: UNCST-2024-R002689
Outcomes Evaluation of Reproductive, Maternal and Newborn Care Interventions Implemented by BAMA in Uganda
REFNo: HS5155ES

General Objective
To evaluate the outcomes of Reproductive, Maternal and Newborn Care interventions at BAMA Supported Sites in Uganda.

Specific Objectives
1. To evaluate the impact of NMH interventions on IMMR and IPMR since 2015
2. To explore factors influencing mortality trends since 2015
3. To document the optimum package of MNH interventions that impacted MMR and PMR
4. To assess the impact of BAMA interventions on HPV vaccination uptake for out-of-school girls as well general population (women aged 25-49) cervical cancer screening and linkage to appropriate services
5. To assess the effect of BAMA project interventions on infant development outcomes and adolescent mother’s physical, social, and mental wellbeing outcomes
6. To determine the feasibility and sustainability of MRP
7. To assess the impact of the implementation of MPS transport solution on MNH outcomes
8. To assess the design and impact of the mentor midwives model on MNH outcomes
9. To determine optimum mentorship package and its impact on quality of care and clinical outcomes

Uganda 2024-12-23 12:03:10 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Winnifred Kansiime Kimara
ID: UNCST-2021-R012131
Faecal exposure behaviours, risk profiles, and predicted efficacy of Water Sanitation and Hygiene interventions in Imvepi, Uganda and Cox’s Bazar, Bangladesh refugee settings
REFNo: HS5190ES

4. To predict the efficacy of suggested interventions on reducing faecal exposure in the private domain in Imvepi and Cox’s Bazar refugee settings (Study IV),3. To determine the factors associated with faecal exposure among children and adults in Imvepi and Cox’s Bazar refugee settings (Study III),2. To determine the faecal exposure risk profile of children and adults in the private and public domain of Imvepi and Cox’s Bazar refugee settings (Study II),1. To explore faecal exposure behaviours and pathways of children and adults in the private and public domain of Imvepi and Cox’s Bazar refugee settings (Study I),To establish the faecal exposure profiles and associated factors in the private and public domain and predict the efficacy of suggested interventions in Imvepi, Uganda and Cox’s Bazar, Bangladesh refugee settings so as to guide exposure reduction interventions.,
Uganda 2024-12-23 12:01:21 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
DANIEL BUGEMBE LULE
ID: UNCST-2024-R015332
DEVELOPMENT OF NOVEL APPROACHES FOR HIV DRUG RESISTANCE DETECTION USING NANOPORE SEQUENCING TECHNOLOGY
REFNo: HS5352ES

Objectives and Hypothesis
Primary Objective
To develop an end-to-end nanopore NGS workflow for the routine clinical detection of HIV drug
resistance (HIVDR).
Secondary Objective
To compare the HIVDR scoring between Sanger and Nanopore sequencing method of matched samples
to evaluate their concordance for detecting drug resistance mutations.
Exploratory Objectives
1. To develop a method for PCR amplification of low plasma viral load samples, genotype these
with the nanopore method and derive HIVDR mutations.
2. To identify improvements to the nanopore base-calling algorithms that may obviate high error
rates.
3. Provide an expeditious end-to-end analysis pipeline for analysis of HIVDR of Nanopore generated
sequences.
4. To establish if the various base-calling errors of the Nanopore sequencing are occurring in a
stochastic or non-stochastic manner.
Uganda 2024-12-23 11:59:00 2027-12-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Identifying Barriers to Infection Prevention & Control Guideline Adherence in Western Uganda.
REFNo: HS5360ES

Primary Objectives The primary objective of the proposed project is to demonstrate the effects of limited physical facility infrastructure, diminished supplies, and gaps in IPC knowledge amongst HCP and how they may relate to IPC practice implementation at the health facility level to inform efficient and effective future improvement efforts. Specific Aims AIM 1: Evaluate adherence to national IPC guidelines across a variety of healthcare facility levels in Western Uganda via a standardized observation protocol through facility-level evaluations. 1A. Guided by Uganda’s national IPC best practices for healthcare facilities and a standardized facility-level checklist adopted from the World Health Organization, we will perform observations of the facility’s physical characteristics, healthcare supplies, and healthcare personnel workflow, including observations of hand hygiene adherence with a standardized checklist. AIM 2: Assess IPC knowledge, attitudes, and practices of healthcare personnel at multiple levels of Uganda’s national healthcare system, identifying primary barriers to National IPC Guideline adherence. 2A. Healthcare Personnel Surveys: Surveys will consist of both qualitative and quantitative elements to ascertain information on their awareness of foundational IPC concepts within national guidelines, circumscribe a working understanding of the implementation of IPC measures across different healthcare facility settings before and after the COVID-19 pandemic, and determine health facility-level attributes that may prevent rigorous adherence to IPC guidelines. 2B. Healthcare Personnel Focus Group Discussions: Focus group discussions will be oriented in such a manner as to ascertain common themes and information on awareness of foundational IPC concepts, gain a perspective on the experience of IPC practices across a variety of facility levels and HCP roles, and understand what limitations are experienced by HCP during their daily patient care-oriented activities. Through these discussions, we hope to gain a working understanding of the implementation of IPC measures across different healthcare facility settings before and after the COVID-19 pandemic, and determine health facility-level attributes, gaps in IPC education and/or training, and HCP workflow concerns that may prevent rigorous adherence to IPC guidelines.
Uganda 2024-12-23 11:57:43 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
Stakeholder perspectives for the approach to treatment recommendations for kids presenting with advanced or incurable cancer
REFNo: HS5203ES

Using the instrument described in 1.1, identify personal, professional, and contextual factors influencing the perspectives and decision-making approaches of key non-physician stakeholders in Uganda in the upfront care of children diagnosed with advanced or incurable cancer through qualitative data collection and analysis.,To adapt an existing instrument for use in Uganda that helps explore the personal, professional, and contextual factors that influence the perspectives and decision-making approaches of key non-physician stakeholders (patients, families, multidisciplinary clinicians), specifically with respect to recommending upfront curative treatment versus non curative treatment (for example, with palliative-intent) in children diagnosed with advanced or incurable cancer in LMICs.,
Uganda 2024-12-23 11:55:35 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julius Duula Waiswa
ID: UNCST-2024-R015879
BURDEN AND SPATIAL DYNAMICS OF TICK SPECIES AMONG CATTLE GRAZING ALONG THE BUFFER ZONE OF LAKE NAKUWA IN KALIRO DISTRICT
REFNo: A529ES

1. Determine the burden of tick species infesting cattle grazing along the buffer zone of Lake Nakuwa.
2. Determine spatial dynamics of the different tick species infesting cattle grazing along the buffer zone of Lake Nakuwa
3. Identify factors promoting and maintaining high tick infestation burdens along the buffer zone of Lake Nakuwa.

Uganda 2024-12-23 11:54:12 2027-12-23 Agricultural Sciences Non-Clinical Trial Degree Award
Edith Namakula
ID: UNCST-2022-R006923
Pethidine versus Morphine use for management of postoperative pain in Mulago National Referral Hospital, Uganda
REFNo: HS5240ES

1. To determine the prevalence of pethidine versus morphine prescription for the management of postoperative pain in MNRH, Uganda.
2. To explore the side effects experienced during the use of pethidine versus morphine for the management of postoperative pain in MNRH, Uganda.
3. To determine the factors associated with pethidine prescription for the management of postoperative pain in MNRH, Uganda.
4. To explore barriers and facilitators of pethidine versus morphine prescription in the management of postoperative pain in MNRH, Uganda.

Uganda 2024-12-23 11:53:21 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Birungi
ID: UNCST-2024-R015642
Receiving cash amidst competing norms: the case of breastfeeding South Sudanese refugees in bidi-bidi settlement, uganda.
REFNo: SS3525ES

To explore how breastfeeding South Sudanese refugees navigate their cultural norms and cope with cash transfer project norms.

Specific objectives.
1. To establish the cultural norms that guide breastfeeding among South Sudanese refugees in bidi-bidi settlement.
2. To examine how beneficiaries relate with the official norms (project and state norms) in bidi-bidi settlement.
3.To assess the impact of cultural norms on the participation of south sudenese refugees in cash transfer interventions in bidi-bidi settlement.
Uganda 2024-12-23 11:52:27 2027-12-23 Social Science and Humanities Non-Clinical Trial Degree Award
JAMMY OMARA
ID: UNCST-2022-R009800
ASSESSING DIFFERENTIAL DIAGNOSES, ASSOCIATED FACTORS AND GEOSPATIAL DISTRIBUTION OF CHRONIC LOWER LIMB ULCERS AMONG ADULTS IN ZOMBO DISTRICT, UGANDA
REFNo: HS5272ES

General objective
To determine differential diagnoses and associated factors for chronic lower limb ulcers among adults in Zombo district.

specific objectives
1. To determine the differential diagnoses for chronic lower limb ulcers among adults in Zombo district
2. To describe the associated factors with chronic lower limb ulcers among adults in Zombo district
3. To describe the geospatial distribution of individuals with chronic lower limb ulcers in Zombo district
Uganda 2024-12-23 11:51:16 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Filippo Ferraro
ID: UNCST-2024-R016002
Key Performance Indicator Framework for refugees integration in Uganda
REFNo: SS3441ES

The main objectives of the study are to:
1. ldentify the specifics support needs of refugees in Uganda.
2. Explore the perception and understanding of refugee’s local people and stakeholders
on the concept of integration.
3. Explore the existing welfare and integration programme available in Uganda.
4. Determine the facilitators and the barriers to the integration of refugees in Uganda.
5. Develop a Key Performance Indicator framework for the integration of refugees in
Uganda.

Italy 2024-12-23 11:50:16 2027-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
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"A prosperous Science and Technology Led Ugandan Society."