Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 6,466
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Fred Bulamba
ID: UNCST-2019-R000026
Non-Physician Anaesthetists’ training and roles in sub-Saharan Africa
REFNo: HS30ES

This study aims to 1) characterise the training programmes currently available for NPAs in sub-Saharan Africa (SSA), with respect to their structure, curricula and teaching methods, 2) characterise the output of NPA training programmes in terms of NPA roles and the proportion of total anaesthesia providers who are NPAs, and 3) explore the experience of key informants in selected locations with regard to NPA training and practice.\r\n
Uganda 2017-04-25 2020-04-25 Medical and Health Sciences Non-degree Award
Joshua Nfambi
ID:
Effect of Moringa oleifera extracts on the HIV model: A study of nutrient bioavailability and immunological responses
REFNo: HS46ES

1. To assess the presence and quantity of micronutrients in Moringa oleifera leaf extracts 2. To determine the bioavailability of the micronutrients in Moringa oleifera in a Murine model 3. To establish the effect of Moringa oleifera leaf extracts on HIV virus replication in T-lymphocytes and macrophages 4. To determine the effect of Moringa oleifera leaf extracts on secretion of chemokines, IL1, 12 TNF α and INF γ in HIV infected cells 5. To determine the effect of Moringa oleifera leaf extracts on the cell mediated immune system of a humanized HIV murine model
Uganda 2017-04-25 2020-04-25 Medical and Health Sciences Non-degree Award
Henry Kajumbula Mawerere
ID: UNCST-2019-R001531
Adaptation and Evaluation of a Direct PCR Based Method for the Diagnosis of Bacteremia among Critically Ill Patients in Uganda
REFNo: HS51ES

4.2.1. To introduce and optimize a broad range qPCR test for diagnosis of bacteremia at the MUCHS molecular biology laboratory 4.2.2. To evaluate the performance of the broad range qPCR among patients at the Mulago ICU and UCI against blood culture 4.2.3. To estimate the prevalence of various etiologic agents of bacteremia among UCI and Mulago ICU patients with sepsis 4.2.4. To determine the antimicrobial susceptibility profiles of the bacterial strains responsible for bacteremia at the UCI and the Mulago ICU
Uganda 2017-04-25 2020-04-25 Medical and Health Sciences Non-degree Award
Iain Darbyshire Andrew
ID:
Identifying Tropical Important Plant Areas in Uganda
REFNo: NS11ES

Tropical Important Plant Areas (TIPAs) are sites of global importance for conserving the world’s plant diversity, measured through three criteria: threatened species, threatened habitats and high botanical richness. This project will support the identification of TIPAs in the forests of west and central Uganda through conducting field surveys of key sites, selected through prior analysis of herbarium data for Uganda. For each site, we will assess its current status including how intact the forest habitats are, what management practices are in place and what threats are evident. Species of high conservation importance will be specifically targeted, and an assessment made of their abundance at each site. Rapid species inventories, including collection of herbarium specimens, will also be carried out particularly at lesser known forest sites. The field data accumulated will feed into the identification of TIPAs based on the presence of threatened species, threatened habitats and assemblages of important species including those of socio-economic value; these will be published online through the IPA database. The current proposed period of fieldwork is a pilot phase of a wider TIPAs project and will focus on selected sites in the southwest of Uganda. It is envisaged that this pilot will support the development and funding of a larger project on TIPAs in Uganda.
UK 2017-04-25 2020-04-25 Natural Sciences Non-degree Award
Isabel Larridon
ID:
C3 and C4 Cyperaceae of Uganda
REFNo: NS12ES

The fieldwork is organised in the context of a project looking at the differential impact of climate change of C3 and C4 plant lineages in Africa. C4 photosynthesis is an evolutionary response to climate change (including aridification). Multiple independent origins of the C4 pathway in Cyperaceae provide ideal opportunities to study the differential response of C3 and C4 lineages to climate change. The largest diversity of C4 Cyperaceae lineages occurs in Africa allowing us to investigate C4 evolution within the unique climatic and biogeographical history of the continent. Africa is undergoing aridification at a scale and level that is only comparable to Australia. Studying adaptation mechanisms in African flora may be key to decipher long-term evolutionary response to global warming in plants. In the overarching project, we aim to apply the novel HybSeq technique to acquire 350+ low-copy targets and high-copy genomic loci evolving across a range of rates, combined with access to newly available fossils providing further calibration dates, to obtain an accurately dated and robust Cyperaceae Tree-of-Life, resolve relationships in C4 Cyperaceae lineages and identify their closest sister C3 lineages. Together with model-based biogeographical methods and present-day and paleoclimatic ecological niche models informed by baseline data from Royal Botanic Gardens Kew’s vast collection of herbarium records, this data will provide key knowledge on how C3 and C4 Cyperaceae lineages have differentially responded to environmental pressures in Africa over the last c. 85 Ma. This will allow modelling how they will respond in future and inform conservation actions.
Belgium 2017-04-25 2020-04-25 Natural Sciences Degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."