Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Helen Byakwaga
ID: UNCST-2019-R001168
A Phase III/IV factorial randomised double-blind trial to compare the addition of dapagliflozin versus placebo, and rosuvastatin/ezetimibe versus pitavastatin, in patients with HIV on integrase strand transfer inhibitor-based antiretroviral therapy with elevated metabolic risk (Optimising metabolic management on integrase-based antiretroviral therapy – the OPTIMAR Study)
REFNo: HS5819ES

To assess the impact of pitavastatin vs. rosuvastatin/ezetimibe from baseline to 48 weeks on: fasting lipids, cardiovascular disease risk assessment measures; inflammatory biomarkers; and safety and tolerability,To assess the impact of dapagliflozin vs. placebo from baseline to 48 weeks on: intermediate markers of cardiovascular disease risk; cardiovascular disease risk assessment measures; clinical consequences of increased body weight; and safety and tolerability of dapagliflozin,To assess the impact of pitavastatin vs. rosuvastatin/ezetimibe on LDL concentration change from baseline to week 24,To assess the impact of dapagliflozin vs. placebo on absolute weight change from baseline to week 24,The overall objective of the study is to examine the impact of dapagliflozin vs. placebo on metabolic parameters in PWH with high metabolic risk who are on INSTI-based ART.,
Uganda 2025-09-30 14:11:23 2028-09-30 Medical and Health Sciences Clinical Trial Non-degree Award
Melody Niwamanya
ID: UNCST-2019-R000928
Gender Equality and Empowerment of Women and Girls (GEEWG) Measurement Toolkit Pilot in Uganda
REFNo: SS4458ES

5. Produce a refined set of tools and practical implementation guidance to inform subsequent pilots and eventual scale-up.,4. Verify that safeguarding, consent/assent, referral pathways, and data protection procedures function effectively and safely in this setting.,3. Assess data quality and preliminary measurement performance of the toolkit to identify items and scales that need refinement for clarity and consistency.,2. Establish cultural and linguistic appropriateness of items across respondent groups and identify questions that require revision based on respondent understanding and contextual fit.,1. Determine feasibility and acceptability of administering the GEEWG toolkit to learners, caregivers, teachers, school committee members, and community leaders in Kyangwali (including length, language, flow, and field logistics).,To pilot and validate a flexible, context-sensitive Gender Equality and Empowerment of Women and Girls (GEEWG) Measurement Toolkit within Kyangwali Refugee Settlement to assess its relevance, accuracy, and usability for capturing gender-transformative outcomes in MYRP-supported education interventions.,
2025-09-29 16:30:10 2028-09-29 Social Science and Humanities Non-degree Award
Prudence Beinamaryo
ID: UNCST-2023-R007239
The feasibility, acceptability and health impact assessment of the co-administration of ivermectin and albendazole vs albendazole alone, in the frame of mass drug administration to school-aged children in Uganda: A large-scale distribution
REFNo: HS6511ES

To assess the health impact of both treatment schemes and compare prevalence reduction of soil-transmitted helminth infections at school level by treatment arm ,To document safety of routine ivermectin-albendazole administration,To document the performance (i.e., coverage and reach) of the two treatment arms,To collect data on implementation-related costs and assess the additional resource needs and costs for the co-administration of ivermectin and albendazole compared to albendazole alone ,To evaluate the acceptability of sensitization and distribution strategies informed by the pilot study of co-administered ivermectin and albendazole among receiving communities,To assess the feasibility (including aspects of training, materials and processes) of the co-administration of ivermectin and albendazole compared to albendazole alone at large-scale in the frame of school-based MDA in Uganda,To assess the feasibility and acceptability of the co-administration of ivermectin and albendazole compared to albendazole alone during school-based MDA in Uganda.,
Uganda 2025-09-29 16:25:20 2028-09-29 Medical and Health Sciences Non-degree Award
MARIA NAMULWANA LOUISE
ID: UNCST-2025-R019516
Evaluating the durability of the immune response to fractional and full dose Yellow Fever vaccination (YEFE/NIFTY Extension Study )
REFNo: HS6461ES

• To describe the current age-stratified seropositivity rates in YEFE and NIFTY participants at 2-8 years after initial vaccination by vaccine dose received, and to compare seropositivity rates across trials and groups including shared data from the MRCG trial.
Uganda 2025-09-26 18:39:14 2028-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catherine Orodriyo
ID: UNCST-2024-R002224
PROCUREMENT MONITROING PRACTICES AND ROAD TRANSPORT SERVICE DELIVERY IN LOCAL GOVERNMENTS IN UGANDA: A CASE STUDY OF ROAD CONSTRUCTION IN ARUA CITY.
REFNo: SS4296ES

1. To assess the impact of performance score cards on road transport service delivery in Arua city.
2. To evaluate the contribution of supervision reports towards road transport service delivery in Arua city.
3. To assess the effectiveness of capacity building on road transport service delivery in Arua city.
4. To examine the moderating effect of procurement monitoring practices on road transport service delivery in Arua city.
Uganda 2025-09-26 18:35:57 2028-09-26 Social Science and Humanities Non-Clinical Trial Degree Award
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