Hannah Kibuuka
ID: UNCST-2020-R014355
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Sub-Study D – Evaluation of Point-of-Care C-reactive Protein Assay Performed on the EnLiSense Rapid ElectroAnalytical Device (READ) Platform Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS5172ES
To validate the CRP assay performed on the READ platform by comparing it to a point-of-care conventional CRP assay previously cleared by the United States Food and Drug Administration (FDA). The results from this substudy are intended to be used for a FDA 510(k) submission for the EnLiSense READ device and CRP assay
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Uganda |
2025-01-10 11:49:48 |
2028-01-10 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Ferdinand Nduwayo
ID: UNCST-2024-R004506
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Development of Comprehensive Seismic Design Guidelines for Earthquake Resistant Design of Buildings in Uganda
REFNo: SIR390ES
(e) To develop comprehensive national structural design guidelines based on modern seismic design codes, aimed at providing engineering practitioners with practical seismic risk mitigation techniques; subsequently leading to sustainable growth and development,(d) To derive spectral displacement, elastic and design pseudo-acceleration spectra representing seismic action in the horizontal direction for key building typologies located in major cities in Uganda,(c) To develop reliable bespoke building exposure models for risk calculations by gathering data on building stock taxonomies and occupancy types,(b) To perform a stochastic event-based probabilistic seismic hazard analysis for Uganda which relies on the available data collected on the seismicity, geology and tectonics of the country,(a) To compile Uganda historical and instrumental earthquake catalogues required for homogenisation, removal of non-Poissonian events and completeness analyses,The main objective of this research proposal is to develop comprehensive earthquake-resistant building design guidelines specifically tailored for Uganda\'s unique geological, seismo-tectonic conditions and available construction materials. These guidelines will facilitate the construction of buildings that can withstand earthquakes, thereby reducing the potential for damage and casualties during seismic events.,
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Burundi |
2025-01-10 11:48:15 |
2028-01-10 |
Engineering and Technology |
Non-Clinical Trial |
Non-degree Award |
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Julius Okuni Boniface
ID: UNCST-2019-R000963
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A One Health Survey of AMR and farming practices that drive Antimicrobial Resistance at Selected Animal-Human-environment Interface in Uganda
REFNo: A539ES
General Objective: To build capacity for antimicrobial resistance (AMR) surveillance and AMR stewardship using a One Health approach.
Specific Objectives:
1. To isolate the AMR resistant E coli and Salmonella from slaughtered chicken, slaughtered cattle and the environment.
2. To determine the phenotypic and genotypic characteristics of Salmonella and pathogenic E. coli present in selected human-animal interfaces in Uganda.
3. To determine the changes in the antimicrobial use by farmers and Veterinarians during COVID19 pandemic.
4. To determine the roles played by different livestock management practices and animal health interventions in escalating AMR in Uganda.
5. To identify and evaluate community based hygienic and disinfection practices that can reduce antibiotic/biocide use.
6. To determine the levels of antimicrobials and biocide residues in slaughtered chicken and cattle cecal samples and abattoir/market wastewater from the selected districts in the country.
Secondary objectives:
To harness the functions of various policy makers in government institution and build capacity and partnerships for AMR reduction with different organisations within Uganda.
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Uganda |
2025-01-10 11:46:51 |
2028-01-10 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
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Ilemobayo Fasogbon Victor
ID: UNCST-2023-R008569
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DEVELOPMENT AND EVALUATION OF AN APTAMER-BASED LATERAL FLOW BIOSENSOR FOR RAPID DETECTION OF Mycoplasma bovis P48 PROTEIN
REFNo: HS4931ES
Evaluation of the aptamer-based biosensor using M. bovis infected milk samples,Construction of the aptamer-based biosensor after optimizing the inherent conditions and components,Characterization of the binding affinity and specificity of the aptamer-target interactions,Selection and optimization of the most sensitive aptamer for application in the lateral flow biosensor through molecular interaction studies on previously reported P48 protein aptamers.,he research aim to develop and evaluate an aptamer-based lateral flow biosensor for the rapid and accurate detection of the Mycoplasma bovis P48 protein in infected samples,
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Nigeria |
2024-12-23 12:36:24 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Paul Matovu
ID: UNCST-2024-R004929
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The Phylogeny of East African Chlorophytum Ker-Gawl. (Asparagaceae), Phylogeography and Conservation of species found in Uganda
REFNo: NS756ES
1. To establish the phylogeny of Chlorophytum species in the FTEA region and put them in a global context.
2. To unravel the phylogenetic and morphological delimitation of problematic taxa and species complexes within Chlorophytum.
3. To establish the spatial phylogeny of Chlorophytum species that occur in Uganda
4. To establish the conservation status of Chlorophytum species in Uganda
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Uganda |
2024-12-23 12:34:57 |
2027-12-23 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
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Francis Ssali
ID: UNCST-2021-R012134
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A5409: A Phase 2 Randomized, Adaptive, Dose-Ranging, Open-Label Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)
REFNo: HS4036ES
1.2 Primary Objectives
1.2.1 To compare MGIT liquid culture TTP slope over the first 6 weeks of treatment for each experimental treatment arm to the SOC arm.
1.2.2 To compare new Grade 3 or higher adverse events (AEs) (safety) over the first 8 weeks of treatment for each experimental treatment arm to the SOC arm.
1.3 Secondary Objectives
1.3.1 To compare time to stable culture conversion by MGIT liquid culture by week 8 for each experimental treatment arm to the SOC arm.
1.3.2 To compare MGIT liquid culture TTP slope over the first 8 weeks of treatment for each experimental treatment arm to the SOC arm.
1.3.3 To compare new Grade 3 or higher AEs (safety) over 26 weeks of treatment for each experimental treatment arm to the SOC arm.
1.3.4 To compare discontinuations of anti-TB drugs for any reason prior to 8 and 26 weeks of treatment for each experimental treatment arm to the SOC arm.
1.3.5 To determine the dose- and exposure-response relationships between experimental drug estimated pharmacokinetic (PK) parameters with safety and efficacy.
1.3.6 To compare a composite of efficacy and safety outcomes using a risk-benefit approach for each experimental treatment arm to the SOC arm.
1.3.7 To compare MGIT liquid culture TTP slope over the first 6 weeks of treatment for Arms 3A-3B and Arms 4A-4B compared to Arm 2.
1.3.8 To compare durable cure by 52 weeks after treatment initiation in each experimental treatment arm to the SOC arm.
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Uganda |
2024-12-23 12:34:14 |
2027-12-23 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Hakimu Sseviiri
ID: UNCST-2024-R004881
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Formalizing and Elevating Workforce Visibility for Marginalized Sanitation Workers in Kampala, Uganda: Unravelling the intended and Unintended Consequences.
REFNo: SS2816ES
4. To co-design multi-stakeholder pathways towards effective formalization, integration and recognition of sanitation workers. ,3. To analyze the multi-dimensional intended and unintended impacts of formalizing and increasing the visibility of the workforce for the most marginalized workers. ,2. To identify and characterize actors involved in the formalization and visibility raising processes in Kampala city. ,1.To determine the different sanitation workers’ formalization and visibility raising initiatives overtime. ,To unravel the intended and unintended consequences of sanitation workers formalization and visibility enrichment in Kampala city, Uganda. ,
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Uganda |
2024-12-23 12:29:36 |
2027-12-23 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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George Alaneme Uwadiegwu
ID: UNCST-2024-R003261
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ARTIFICIAL INTELLIGENCE PREDICTIVE MODELLING OF MECHANICAL AND RHEOLOGICAL PROPERTIES OF GEOPOLYMER-CONCRETE MADE FROM BLENDED BAGASSE AND BANANA-PEEL-ASH
REFNo: SIR365ES
i. To characterize Bagasse ash (BA) and Banana peel ash (BPA) as a geopolymer precursor
ii. To ascertain the optimal combination of the concrete mixture incorporating Bagasse ash (BA) and Banana peel ash (BPA) to replace ordinary Portland cement.
iii. To determine the mechanical and rheological properties of Bagasse ash (BA) and Banana peel ash (BPA) and blended geopolymer concrete matrix.
iv. To develop soft computing predictive models of ANN, GEP and ANFIS to explore the relationships between the Alkalis-activated binder blend and the rheological and mechanical strength response.
v. To compare and validate the models developed in (iv).
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Nigeria |
2024-12-23 12:28:18 |
2027-12-23 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
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Sarah Wambete Namee
ID: UNCST-2024-R003551
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Effectiveness Of A Health Belief Model (HBM)-Based Educational Intervention On Tuberculosis (TB) Treatment Adherence Among Tb Patients In Two Hospitals In Kampala, Uganda: A Randomized Control Trial
REFNo: HS4558ES
To assess the effectiveness of a Health Belief Model (HBM)-based educational intervention on TB treatment Adherence level among TB patients in two hospitals in Kampala, Uganda.
1.To assess the level of TB knowledge among TB patients in two hospitals in Kampala, Uganda.
2.To assess the health beliefs of TB patients towards tuberculosis in two hospitals in Kampala, Uganda
3.To assess the quality of life of TB patients in two hospitals in Kampala, Uganda.
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Uganda |
2024-12-23 12:26:18 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Christine Piloya Ruth
ID: UNCST-2024-R003592
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Patriarchy and Women Engagement in Environmental Conservation in Northern Uganda: A Case of Gulu District
REFNo: SS2986ES
4. To propose a framework or a model for effective engagement of women in environmental conservation in patriarchal societies.,3. To establish the effectiveness of the strategies used by stakeholders in fostering women’s engagement in environmental conservation within a patriarchal setting in Gulu district.,2. To investigate the extent to which the distinguishing features of patriarchy affect women’s engagement in environmental conservation in Gulu district.,1. To examine in context, the socio-cultural roles performed by women in environmental conservation within the patriarchal structure in Gulu district. ,To examine the extent to which patriarchy affects women\'s engagement in environmental conservation in Gulu district.,
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Uganda |
2024-12-23 12:24:42 |
2027-12-23 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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