Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jospeh  Wandega
ID:
PhotoVoice For PeaceBuilding Between Refugees and Hosting Communities.
REFNo: SS1702ES

Determine how photographs developed through the project can be brought into wider public and community spaces through exhibitions as a mechanism for wider social integration and peacebuilding,Distinguish the knowledges and practices that women and youth in Oruchinga and Kampala have that contributes to building peace within their communities. Compare these knowledges to evaluate how they might benefit other peacebuilding contexts,Observe and assess participant interactions across the two sites holistically over the course of the PhotoVoice process: research design, training and photograph-taking, sharing and selecting photographs and exhibition,Identify the main drivers of conflict and peace within refugee communities and between refugees and host communities in Oruchinga and Kampala,Main hypothesis: By bringing together refugee and hosting Ugandan communities to participate in a PhotoVoice process that explores issues of conflict and peace each group faces on a daily basis, that divides between groups can be bridged to enhance refugee-host peacebuilding efforts,
Uganda 2023-09-27 16:57:12 2026-09-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eve  Masawi
ID:
EXAMINING THE ADOPTION OF MOBILE JOURNALISM IN UGANDAN NEWSROOMS: A CASE OF NBS TV AND NTV
REFNo: SS1609ES

To examine the adoption of mobile journalism in newsrooms in Uganda using the case study of NBS TV and NTV newsrooms.,3. To explore the challenges and opportunities presented by adoption of MoJo in NBS TV and NTV newsrooms. ,2. To explore factors driving the adoption of MoJo or lack of it in NBS TV and NTV newsrooms.,1. To establish the stage of MoJo adoption in NBS TV and NTV newsrooms,
Uganda 2023-09-27 16:52:12 2026-09-27 Social Science and Humanities Non-Clinical Trial Degree Award
victoria nakibuuka
ID: UNCST-2020-R014741
The impact of oxygen management and ROP Screening on the prevention of Retinopathy of Prematurity (ROP) in Sub-Saharan Africa
REFNo: HS2674ES

To describe the characteristics of premature infants meeting the ROP screening criteria (July 2019 to July 2021) and (August 2022 to August 2024)

b)To describe the characteristics of premature infants referred for ROP follow-up during July 2019 to July 2021 period

c)To examine the relationship between infants’ prenatal, perinatal, and postnatal health characteristics and the onset and severity of ROP.

d) To examine the relationship between the receipt of blended and regulated oxygen regulation on the onset and severity of ROP development, oxygen-related comorbidities, and neonatal survival.

e)To examine the relationship between ROP screening, examinations, and treatment on the onset and severity of ROP.

Uganda 2023-09-27 16:50:50 2026-09-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
TUMUSHABE INNOCENT KAJUBA
ID:
DETERMINING SAFE WATER SUPPLY SOURCES AND RURAL COMMUNITIES ACCESS IN BWAMBARA SUB-COUNTY, RUKUNGIRI DISTRICT. A CASE STUDY OF KIKONGI PARISH
REFNo: SS1636ES

The general objective of this research is to determine the safe water supply sources and rural communities access in Bwambara Sub-County, Rukungiri District with a focus on Kikongi Parish.

This research is guided by the following objectives:
i. To map the spatial and temporal distribution of safe water supply sources in Kikongi Parish.
ii. To determine the number of households with access to safe water supply sources in Kikongi Parish.
iii. To determine the most feasible portable water supply system in the provision of safe water to the residents of Kikongi Parish.

Uganda 2023-09-27 16:45:18 2026-09-27 Social Science and Humanities Non-Clinical Trial Degree Award
Herbert Kamusiime
ID:
"Measures For Advancing Gender Equality (Magnet): Testing New Tools to Measure Women’s Agency in Uganda.”
REFNo: SS1998ES

MAGNET is seeking to test seven new agency measurement tools in Uganda as part of the MAGNET portfolio:
1. Administration of vignettes (stories depicting the extent to which husbands and wives engage in different modes of joint decision-making over large household purchases).
2. Administration of a few open-ended questions to capture women's decision-making should be recorded with high-quality audio.
3. Survey module to capture persuasion behaviours in the household.
4. Group-level module to capture women’s collective agency
5. Automatic cognition test on an electronic tablet to capture respondents' internalized beliefs about the suitability of women vs men engaging in certain occupations.
6. The critical consciousness scale captures respondents' critical reflection, critical action and motivation regarding household decision-making, work outside the household, and political participation.
7. Survey module to capture benefits from asset ownership.
These tools have been newly developed by MAGNET. In addition, we also plan to ask enumerators a series of questions on their background and attitudes before enumerator training to understand better how enumerator characteristics relate to measured outcomes.

Uganda 2023-09-26 9:31:17 2026-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rogers Kajabwangu
ID: UNCST-2022-R010077
Cervical cancer and metabolic syndrome among women utilizing cervical cancer prevention and treatment services at Mbarara regional referral hospitals
REFNo: HS3053ES

To describe the disease burden and trends of cervical cancer, and its relationship with Metabolic syndrome among women at Mbarara regional referral hospital.
Uganda 2023-09-26 9:29:37 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
ULTRA Covi-Catch Ag. Laymen Study including Usability. "Clinical Performance Study Plan - CPSP nr. BSS-CPH 22-054"
REFNo: HS2933ES

Part 3: Observed untrained user study o Evaluation of test results and interpretations when performed by laymen in a self-testing environment while being observed by healthcare providers. These observations will be captured using a questionnaire-based survey.,art 2: Results interpretation study o Reading and interpretation of 6 contrived devices by a minimum of 100 laypersons while being supervised by a neutral healthcare provider. The contrived devices should reflect the different ranges of reactivity: − non-reactive (x 1) − reactive (x 1) − weak reactive (x 2) − invalid (x 2).,Part 1: Labelling comprehension study o Questionnaire-based-survey to assess whether the key messages and instructions from packaging and labelling are understandable and easy to follow.,The objective of this laymen study is to establish the usability of the ULTRA Covi-Catch Ag in a self-testing environment. More specifically, the study will assess whether the instructions for use and labels are clear and understandable and whether the test can be performed correctly by laypersons.,
Uganda 2023-09-26 12:24:11 2026-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phillip Ssekamatte
ID:
IMMUNOLOGICAL, METABOLIC AND GENE TRANSCRIPTIONAL CHANGES AMONG PATIENTS WITH TUBERCULOSIS AND TYPE 2 DIABETES MELLITUS IN UGANDA (IMG STUDY)
REFNo: HS2990ES

Sub-study 1: To evaluate the immunologic, metabolic, and genetic mechanisms of TB susceptibility in DM. Sub-study 2: To assess baseline differences in Mtb-specific CD4+ and CD8+ T cell functional phenotypes and memory frequencies among LTBI and ATB patients with and without T2DM. Sub-study 3: To determine the effect of TB preventive therapy using isoniazid therapy on the function and memory frequency of Mtb-specific CD4+ and CD8+ T cells among LTBI and ATB patients with and without T2DM. Sub-study 4: To profile baseline immune-metabolic changes among LTBI and ATB patients with and without T2DM. Sub-study 5: To investigate gene expression differences in the 6-gene transcriptome signature (TB RISK6; GBP2, SERPING1, FCGR1B, TRMT2A, SDR39U1, TUBGCP6) among LTBI and ATB patients with and without T2DM at baseline and 6 months of TB preventive therapy.
Uganda 2023-09-26 12:13:20 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Ambaru  Ojia Jacinta
ID:
PREVALENCE OF SEPSIS, 30 DAY CASE FATALITY RATIO, AND OPTIMAL MORTALITY RISK SCORES AMONG POST-CHEMOTHERAPY CANCER PATIENTS WITH INFECTION AT ONCOLOGY CLINIC MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS3111ES

Aim 3. To determine the optimal mortality risk score to predict 30-day mortality for post cancer-chemotherapy patients with infection at oncology clinic Mbarara regional referral hospital,Aim 2. To determine the 30-day case fatality ratio for post-cancer chemotherapy patients with infection at oncology clinic Mbarara regional referral hospital ,Aim 1: To determine the point prevalence of sepsis in post-cancer chemotherapy patients with infection, according to mortality risk scores (qSOFA, UVA, SIRS), at Mbarara regional referral hospital ,To determine the prevalence of sepsis, 30-day case fatality ratio and optimal mortality risk score, among patients with post-cancer chemotherapy infection at oncology clinic MRRH,
Uganda 2023-09-26 12:11:47 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
MARTIN CHEBET
ID: UNCST-2021-R013905
THE INCIDENCE AND AETIOLOGY OF STILLBIRTHS IN EASTERN UGANDA
REFNo: HS3112ES

3. To assess the acceptability of minimal invasive autopsy in Eastern Uganda,2. To determine the infections associated with stillbirths in a regional referral hospital in eastern Uganda,1. To determine the incidence of and risk factors for stillbirths in a cluster-randomised trial cohort of pregnant women (the BabyGel trial) ,
Uganda 2023-09-26 12:04:01 2026-09-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Hellen Tabea
ID:
THE EXPERIENCE OF CONSECRATED PERSONS ON GRIEF AND COPING UPON THE LOSS OF A /RELIGIOUS/FAMILY MEMBER- UGANDA
REFNo: SS1927ES

To assess the religious and cultural factors influencing consecrated persons when faced with loss.,To find out how consecrated persons manage socio and economic factors to handle medical, psychological and moral issues in grief and loss.,To examine how consecrated member grief and mechanics of coping with loss of a member/family,To asses the experience of the consecrated persons in Uganda upon the less of a religious or family member.,
Uganda 2023-09-26 11:59:11 2026-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Florence Asiimwe Munyonyo
ID:
A Phenomenological Study of Lived Experiences of Returnee Ugandan Migrant Domestic Workers from Saudi Arabia
REFNo: SS1905ES

4. To inform policy reforms for regulating the sector to maximize the benefits for the development of all stakeholders.,3. To examine how the lived experiences affected the realization of the goals for seeking employment in Saudi Arabia. ,2. To evaluate the lived experiences of returnee Ugandan migrant domestic workers before, during and when they return from Saudi Arabia. ,To examine the push and pull factors why returnee Ugandan migrant domestic workers seek employment in Saudi Arabia,
Uganda 2023-09-26 11:56:57 2026-09-26 Social Science and Humanities Non-Clinical Trial Degree Award
Adoke Yeka
ID: UNCST-2021-R004300
PLATINUM: A multi-part, multi-center PLATform study to assess the efficacy, safety, tolerability and pharmacokinetics of anti-malarial agents administered as monotherapy at multiple dose levels and/or combination therapy IN patients with Uncomplicated Plasmodium falciparum Malaria.
REFNo: HS2817ES

Part A: To assess the parasite clearance time (PCT) of oral doses of an anti- malarial agent administered as monotherapy in patients with uncomplicated
P. falciparum malaria
Part B: To assess the effect on adjusted 28-day cure rate of an anti-malarial agent administered orally as combination therapy versus the standard of care (SoC) in patients with uncomplicated P. falciparum malaria.
Part A: To assess the effect on adjusted 28-day cure rate of an anti-malarial agent administered orally as monotherapy in patients with uncomplicated
P. falciparum malaria
Part B: To assess the parasite clearance time (PCT) of oral combinations of anti-malarial agents versus SoC in patients with uncomplicated P. falciparum malaria
All parts:
To characterize PK of each anti-malarial agent administered orally as monotherapy [Part A] and/or as combination therapy [Part B] in patients with uncomplicated P. falciparum malaria
To assess the safety and tolerability of each anti-malarial agent administered orally as monotherapy [Part A] and/or as combination therapy versus SoC [Part B] in patients with uncomplicated P. falciparum malaria


Uganda 2023-09-26 11:55:15 2026-09-26 Medical and Health Sciences Clinical Trial Non-degree Award
Christine Kyarituha Arinaitwe
ID:
Determinants of nutrition outcomes of adolescent girls in Rukiga District.
REFNo: NS507ES

General Objective
To assess the determinants of nutrition outcomes of adolescent girls aged 10-14 years in Primary School in Rukiga district, Western Uganda.
Specific Objectives
1.To assess the nutritional status among adolescent girls aged 10-14 Years, Rukiga District.
2.To assess the diet quality with emphasis on Iron-rich foods consumed by adolescent girls aged 10-14 years in Rukiga district.
3.Assess the dietary knowledge among adolescent girls aged 10-14 years in Rukiga District.
4.Establish the relationship between the nutrition status and nutritional , morbidity ,lack of breakfast and snacking among adolescent girls aged 10-14 years in
Rukiga District
5.Assess the perceptions of community members regarding the diet of adolescent girls in Rukiga District.

Uganda 2023-09-26 11:06:52 2026-09-26 Natural Sciences Non-Clinical Trial Degree Award
Eve  Namisango
ID: UNCST-2021-R014038
Piloting a measure of gender competency among family planning providers
REFNo: SS1567ES

The overall goal of the study is to pilot test a survey instrument that measures gender competency among family planning providers. ,
Uganda 2023-09-26 10:58:18 2026-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Judith Nalukwago
ID:
Uganda Social and Behavior Change Project Assessment
REFNo: SS1350ES

General objective
The general objective of the assessment is to contribute to the ongoing update for the estimates of key programmatic and performance indicators so as to get an understanding of impact and sustainability of the SBCA intervention.
Specific objectives
To provide evidence to inform the design, implementation, and evaluation of project specific social and behaviour change (SBC) interventions.
To determine the status of key project indicators.

Uganda 2023-09-26 10:57:03 2026-09-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID:
ACE-Polymorphisms in COVID-19/Ma1aria and COVID19/TB Co-infections in Uganda: A substudy of the CCP project
REFNo: HS3026ES

General objective:

The aim of this study is to describe the role of ACE polymorphisms in SARS-CoV-2/ Malaria and SARS-CoV-2/TB co-infections in Uganda.
Specific objectives:

1. To determine the prevalence of Malaria/COVID-19 and TB/COVID-19 coinfections in Uganda.
2. Describe the immunological markers (cytokines) associated with TB/ COVID-19 and malaria/COVID-19 co-infections.
3. Describe the ACE 2 gene polymorphisms associated with TB/COVID-19 and
Malaria/COVID-19 in Uganda

Uganda 2023-09-26 10:55:09 2026-09-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lorenzo Casaburi
ID:
Land Usage, Land Markets and Economic Development: Evidence from Uganda
REFNo: SS1970ES

This research program that will shed light on the relationship among land markets, land usage, and economic development in Uganda. The research is based on a collaboration with the Ministry of Lands, Housing & Urban Development and analysis of land registry records of the National Land Information System (NLIC). The researchers will match these data with other data sources, including remote sensing images, to create a unique parcel level longitudinal database on ownership, market transactions, and land usage.
Italy 2023-09-25 15:44:10 2026-09-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
ESTHER IMEDE
ID: UNCST-2023-R007135
Understanding Immunity following Tdap vaccination in pregnant women living with HIV – B and T cell responses.
REFNo: HS2987ES

Primary Objective
To determine the B and T cell responses following Tdap vaccine given in pregnancy to women living with HIV.

Secondary Objective
1. To determine T and B cell responses at 28 days post-vaccination in TDaP-vaccinated vs TDaP -unvaccinated pregnant women and whether this differs by maternal HIV status.
2. To determine T and B cell responses in cord blood of TDaP -vaccinated vs TDaP -unvaccinated pregnant women and whether this differs by maternal HIV status.
3. To determine T and B cell responses in infants born to TDaP vaccinated vs TDaP -unvaccinated pregnant women 4 weeks after the completion of a series of primary vaccination with 3 doses of whole cell pertussis vaccine, and whether this differs by maternal HIV status.

Uganda 2023-09-25 15:41:44 2026-09-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Jonathan Mayito
ID: UNCST-2019-R000490
ANTIBIOTIC RESISTANCE RELATED MORTALITY AND DISABILITY-ADJUSTED LIFE YEARS AT SELECT UGANDA REGIONAL REFERRAL HOSPITALS
REFNo: HS3088ES

To determine the antibiotic-resistant infections-related disability-adjusted years among HIV-infected versus uninfected individuals in a one-year period at four Regional Referral Hospitals in Uganda.,To determine the antibiotic-resistant infections attributable mortality among HIV-infected versus uninfected individuals in a one-year period at four Regional Referral Hospitals in Uganda.,To determine the incidence of antibiotic-resistant infections among HIV-infected versus uninfected individuals in a one-year period at four Regional Referral Hospitals in Uganda.,
Uganda 2023-09-25 15:39:55 2026-09-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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